BDBM86282 6-Chloro-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol; hydrobromide::CAS_1218::CHEMBL553503::NSC_1218::SKF 81297::cid_11957706

SMILES Oc1cc2C(CNCCc2c(Cl)c1O)c1ccccc1

InChI Key InChIKey=GHWJEDJMOVUXEC-UHFFFAOYSA-N

Data  9 KI  3 IC50  7 EC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 86282   

TargetD(1A) dopamine receptor(RAT)
Harvard University

Curated by PDSP Ki Database
LigandPNGBDBM86282(6-Chloro-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]az...)
Affinity DataKi:  1.90nMMore data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM86282(6-Chloro-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]az...)
Affinity DataKi:  7nMAssay Description:The compound was evaluated for the dissociation constant for inhibiting the binding of [3H]-SCH- 23390 at dopamine receptor D1More data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM86282(6-Chloro-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]az...)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]-SCH23390 from wild type human D1R expressed in HEK293 cell membranes incubated for 90 mins by scintillation counting based compe...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM86282(6-Chloro-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]az...)
Affinity DataKi:  310nMAssay Description:The compound was evaluated for the binding affinity towards dopamine receptor D2 at high affinity state.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(RAT)
Harvard University

Curated by PDSP Ki Database
LigandPNGBDBM86282(6-Chloro-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]az...)
Affinity DataKi:  509nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Harvard University

Curated by PDSP Ki Database
LigandPNGBDBM86282(6-Chloro-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]az...)
Affinity DataKi:  995nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Harvard University

Curated by PDSP Ki Database
LigandPNGBDBM86282(6-Chloro-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]az...)
Affinity DataKi:  1.27E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM86282(6-Chloro-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]az...)
Affinity DataKi:  8.00E+3nMAssay Description:The compound was evaluated for the binding affinity towards dopamine receptor D2 at low affinity state.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Harvard University

Curated by PDSP Ki Database
LigandPNGBDBM86282(6-Chloro-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]az...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed