BDBM8740 1-[(3-nitrophenyl)methyl]-4-(thiophen-3-yl)-1H-imidazole::Disubstituted imidazole 8

SMILES O=N(=O)c1cccc(Cn2cnc(c2)-c2ccsc2)c1

InChI Key InChIKey=UNSOKCLOXGBFRH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 8740   

TargetEnoyl-[acyl-carrier-protein] reductase [NADH] FabI(Escherichia coli)
Glaxosmithkline

LigandPNGBDBM8740(1-[(3-nitrophenyl)methyl]-4-(thiophen-3-yl)-1H-imi...)
Affinity DataIC50:  2.69E+4nMT: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus)
Glaxosmithkline

LigandPNGBDBM8740(1-[(3-nitrophenyl)methyl]-4-(thiophen-3-yl)-1H-imi...)
Affinity DataIC50:  1.47E+4nMpH: 6.5 T: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed