BDBM8757 (4R)-4-benzyl-2-(thiophen-3-yl)-4,5-dihydro-1,3-oxazole::oxazoline 32

SMILES C([C@@H]1COC(=N1)c1ccsc1)c1ccccc1

InChI Key InChIKey=HUHVJSXYULHZJW-CYBMUJFWSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 8757   

TargetEnoyl-[acyl-carrier-protein] reductase [NADH] FabI(Escherichia coli)
Glaxosmithkline

LigandPNGBDBM8757((4R)-4-benzyl-2-(thiophen-3-yl)-4,5-dihydro-1,3-ox...)
Affinity DataIC50: >1.00E+5nMT: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus)
Glaxosmithkline

LigandPNGBDBM8757((4R)-4-benzyl-2-(thiophen-3-yl)-4,5-dihydro-1,3-ox...)
Affinity DataIC50: >1.00E+5nMpH: 6.5 T: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed