BDBM8899 1-(6-Methoxy-3,4-dihydronaphthalen-2-yl)-1H-imidazole::Dihydronaphthalene 14::US9271963, 46

SMILES COc1ccc2C=C(CCc2c1)n1ccnc1

InChI Key InChIKey=MQEMKMXSOMLZBI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 8899   

TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8899(1-(6-Methoxy-3,4-dihydronaphthalen-2-yl)-1H-imidaz...)
Affinity DataIC50:  763nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8899(1-(6-Methoxy-3,4-dihydronaphthalen-2-yl)-1H-imidaz...)
Affinity DataIC50:  763nMT: 2°CAssay Description:V79 MZh11B1 and V79 MZh 11B2 cells (8˙10^5 cells per well) were grown to confluency on 24-well cell culture plates with 1.9 cm^2 culture area per...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8899(1-(6-Methoxy-3,4-dihydronaphthalen-2-yl)-1H-imidaz...)
Affinity DataIC50:  411nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed