BDBM8961 1,2,3,4-tetrahydro-9-acridinamine::1,2,3,4-tetrahydroacridin-9-amine::9-THA::9-amino-1,2,3,4-tetrahydroacridine (THA)::CHEMBL1337960::CHEMBL95::Cognex::Tacrine::Tracine::US8999994, Tacrine::cid_1935::tacrine.HCl
SMILES c1ccc2c(c1)c(c3c(n2)CCCC3)N
InChI Key InChIKey=YLJREFDVOIBQDA-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 845 hits for monomerid = 8961
Affinity DataIC50: 0.0244nMAssay Description:Enzyme activity using acetylcholinesterase (AChE) and butyrylcholinesterase (BChE).More data for this Ligand-Target Pair
Affinity DataIC50: 0.0267nMAssay Description:Inhibition of BChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of horse serum BuChE using butyrylthiocholine as substrate pretreated for 10 mins followed by substrate addition measured after 15 mins by...More data for this Ligand-Target Pair
Affinity DataKi: 0.150nMAssay Description:Inhibition constant determined against Acetylcholinesterase (AChE) receptor.More data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:In vitro inhibitory activity against Butyrylcholinesterase (BChE) in human serumMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate incubated for 15 mins followed by substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated with enzyme for 5 mins prior to substrate addition measured...More data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibition of electric eel AChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured eve...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine chloride as substrate preincubated for 5 mins followed by substrate addition measured after ...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured after 5...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of equine serum BuChE preincubated for 5 mins followed by butyrylthiocholine iodide substrate addition measured after 5 mins by Ellman's m...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of equine serum BuChE after 5 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of BuChE in horse serum pre-incubated for 5 mins before addition of butyrylthiocholine iodide substrate by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine chloride as substrate preincubated for 5 mins followed by substrate addition measured after ...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of equine serum BuChE using BTC as substrate preincubated with enzyme for 5 mins followed by substrate addition for 5 mins by Ellman's met...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human BChE using butyrylthiocholine iodide as substrate measured for 3 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3.16nMAssay Description:Inhibition of AChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured every mi...More data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Inhibition of horse AChE by colorimetric Ellman assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured every mi...More data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:Inhibition of BuChE in equine serum using butyrylthiocholine iodide as substrate preincubated with enzyme for 10 mins prior to substrate challenge me...More data for this Ligand-Target Pair
Affinity DataIC50: 3.70nMAssay Description:Inhibition of equine serum BChEMore data for this Ligand-Target Pair
Affinity DataIC50: 3.70nMAssay Description:Inhibition of equine serum BChEMore data for this Ligand-Target Pair
Affinity DataIC50: 3.80nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine chloride substrate incubated for 5 mins before substrate addition measured at 3 min interva...More data for this Ligand-Target Pair
Affinity DataIC50: 3.80nMAssay Description:Inhibition of equine serum butyrylcholine esterase using butyrylcholine chloride as substrate incubated for 5 mins prior to substrate addition measur...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of equine serum BuChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of horse serum butyrylcholine esterase in presence of acetylcholine substrate by chemiluminescent assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of BChE in horse serum using butyrylthiocholine iodide as substrate after 120 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of equine serum BuChE using S-butyrylthiocholine as substrate at by DTNB reagent based spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of horse serum BChE by spectrophotometry based Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 4.40nMAssay Description:Inhibition of BChE in equine serum using butyrylthiocholine iodide substrate by Ellman assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Inhibition of equine serum BChE using ATC iodide substrate by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.90nMAssay Description:Inhibition of horse serum BChE preincubated for 5 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of horse serum BChEMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of equine serum BChE by modified Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 5.10nMAssay Description:Inhibition of BuChE by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.10nMAssay Description:Inhibition of equine BChE by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.10nMAssay Description:Inhibition of horse serum BuChE pre-incubated for 10 mins before addition of butyrylthiocholine iodide substrate and further incubated for 15 mins by...More data for this Ligand-Target Pair
Affinity DataIC50: 5.10nMAssay Description:Inhibition of BuChE from equine serumMore data for this Ligand-Target Pair
Affinity DataIC50: 5.13nMAssay Description:Inhibition of horse AChE by colorimetric Ellman assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.13nMAssay Description:Inhibition of BChE from equine serum by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 5.20nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate incubated for 10 mins followed by substrate addition by DTNB-reagent ba...More data for this Ligand-Target Pair
Affinity DataIC50: 5.20nMAssay Description:Inhibition of equine serum BuChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 5.20nMAssay Description:Inhibition of horse serum BChE after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 5.20nMAssay Description:Inhibition of horse serum BChE using butrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured for 10 min...More data for this Ligand-Target Pair
Affinity DataIC50: 5.20nMAssay Description:Inhibition of Equus caballus BChE preincubated for 10 mins measured after 15 mins by Ellman's methodMore data for this Ligand-Target Pair

3D Structure (crystal)