BDBM9007 7-(1,2,3,4-Tetrahydro-acridin-9-ylamino)-heptanoic acid [2-(1H-indol-3-yl)-ethyl]-amide::N-[2-(1H-indol-3-yl)ethyl]-7-(1,2,3,4-tetrahydroacridin-9-ylamino)heptanamide::Tacrine-Melatonin Hybrid 3b
SMILES O=C(CCCCCCNc1c2CCCCc2nc2ccccc12)NCCc1c[nH]c2ccccc12
InChI Key InChIKey=XHISNFCRWZVULB-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 9007
Affinity DataIC50: 1nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.950nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Csir-Central Drug Research Institute
Curated by ChEMBL
Csir-Central Drug Research Institute
Curated by ChEMBL
Affinity DataIC50: 0nMAssay Description:Inhibition of human erythrocyte acetylcholinesterase using acetylthiocholine as substrate by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 6.80nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Csir-Central Drug Research Institute
Curated by ChEMBL
Csir-Central Drug Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair