BDBM9030 (2E)-N-{6-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]hexyl}-3-(1H-indol-3-yl)prop-2-enamide::Indole-Tacrine Heterodimer 13::N-[6-(6-Chloro-1,2,3,4-tetrahydroacridin-9-ylamino)-hexyl]-3-(1H-indol-3-yl)acrylamide

SMILES Clc1ccc2c(NCCCCCCNC(=O)\C=C\c3c[nH]c4ccccc34)c3CCCCc3nc2c1

InChI Key InChIKey=GFHYZPMZHCOIER-DTQAZKPQSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 9030   

TargetAcetylcholinesterase(Bos taurus (bovine))
Neuropharma

LigandPNGBDBM9030((2E)-N-{6-[(6-chloro-1,2,3,4-tetrahydroacridin-9-y...)
Affinity DataIC50:  18nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM9030((2E)-N-{6-[(6-chloro-1,2,3,4-tetrahydroacridin-9-y...)
Affinity DataIC50:  18nMAssay Description:Inhibition of AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Neuropharma

LigandPNGBDBM9030((2E)-N-{6-[(6-chloro-1,2,3,4-tetrahydroacridin-9-y...)
Affinity DataIC50:  77nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed