BDBM9041 2-(1H-indol-3-yl)ethyl N-{5-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]pentyl}carbamate::Indole-Tacrine Heterodimer 27::[5-(6-Chloro-1,2,3,4-tetrahydroacridin-9-ylamino)-pentyl]carbamic Acid 2-(1H-Indol-3-yl)ethyl Ester

SMILES Clc1ccc2c(NCCCCCNC(=O)OCCc3c[nH]c4ccccc34)c3CCCCc3nc2c1

InChI Key InChIKey=LYBXKEJTVIPNNF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 9041   

TargetCholinesterase(Homo sapiens (Human))
Neuropharma

LigandPNGBDBM9041(2-(1H-indol-3-yl)ethyl N-{5-[(6-chloro-1,2,3,4-tet...)
Affinity DataIC50:  136nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
Neuropharma

LigandPNGBDBM9041(2-(1H-indol-3-yl)ethyl N-{5-[(6-chloro-1,2,3,4-tet...)
Affinity DataIC50:  1.5nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed