BDBM91627 12t::alpha7 agonists 12t
SMILES CN1[C@H]2CC[C@@H]1C[C@H](C2)n1cc(CNC(=O)c2ccco2)nn1
InChI Key InChIKey=MKJMQJPHIUSFQY-BTTYYORXSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 91627
Affinity DataKi: 210nM ΔG°: -8.95kcal/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ?l of 0.2 mg/ml an...More data for this Ligand-Target Pair
Affinity DataKi: 1.40E+3nM ΔG°: -7.85kcal/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ?l of 0.2 mg/ml an...More data for this Ligand-Target Pair
Affinity DataKi: >5.00E+3nM ΔG°: >-7.11kcal/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ?l of 0.2 mg/ml an...More data for this Ligand-Target Pair
Affinity DataKi: >5.00E+3nM ΔG°: >-7.11kcal/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ?l of 0.2 mg/ml an...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
University of California San Diego
University of California San Diego
Affinity DataKi: 2.00E+4nM ΔG°: -6.66kcal/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ?l of 0.2 mg/ml an...More data for this Ligand-Target Pair
Affinity DataKi: >3.00E+4nM ΔG°: >-6.41kcal/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ?l of 0.2 mg/ml an...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California San Diego
University of California San Diego
Affinity DataEC50: >3.00E+4nMpH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ?l of 0.2 mg/ml an...More data for this Ligand-Target Pair