BDBM9237 US8835444, 4.3::US8835444, 4.8

SMILES Cc1cc(C)n(C[C@H]2CC[C@@H](CC2)NC(=O)c2cc(Cl)cnc2C)n1

InChI Key InChIKey=FZPRQRQELHONGW-JCNLHEQBSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 9237   

TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM9237(US8835444, 4.3 | US8835444, 4.8)
Affinity DataIC50:  88nMAssay Description:Chinese hamster ovary (CHO) cells expressing either the human or rat recombinant CRF-1 or human CRF-2alpha (Chen et al, Proc Natl Acad Sci USA 90, 89...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM9237(US8835444, 4.3 | US8835444, 4.8)
Affinity DataIC50:  350nMAssay Description:Chinese hamster ovary (CHO) cells expressing either the human recombinant CRF-1 or CRF-2a receptors (Chen et al., Proc Natl Acad Sci USA 90, 8967-897...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM9237(US8835444, 4.3 | US8835444, 4.8)
Affinity DataIC50:  262nMAssay Description:Chinese hamster ovary (CHO) cells expressing either the human or rat recombinant CRF-1 or human CRF-2alpha (Chen et al, Proc Natl Acad Sci USA 90, 89...More data for this Ligand-Target Pair
In DepthDetails US Patent