BDBM92403 PDK1 inhibitor, 4

SMILES COc1ccc(cc1)C#Cc1ccc2ncc3ncn(-c4ccc(CCN)cc4)c3c2c1

InChI Key InChIKey=YKDDVFSLJZJKFP-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 92403   

Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM92403(PDK1 inhibitor, 4)
Affinity DataEC50:  200nMAssay Description:Enzyme potency (PDK1 EC50)was determined using recombinant, purified full-length human PDK1 enzyme and AKT-Thr-308-tide as substrate.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed