BDBM92900 CHEMBL1835117::L-Arginine, 2::NMMA, 2

SMILES CN=C(N)NCCC[C@H](N)C(O)=O

InChI Key InChIKey=NTNWOCRCBQPEKQ-YFKPBYRVSA-N

Data  5 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 92900   

TargetNitric oxide synthase, brain(Homo sapiens (Human))
The University of Texas

LigandPNGBDBM92900(CHEMBL1835117 | L-Arginine, 2 | NMMA, 2)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition assay using DDAH-1 and nNOS.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
The University of Texas

LigandPNGBDBM92900(CHEMBL1835117 | L-Arginine, 2 | NMMA, 2)
Affinity DataKi:  1.31E+5nMAssay Description:Inhibition assay using DDAH-1 and nNOS.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
The University of Texas

LigandPNGBDBM92900(CHEMBL1835117 | L-Arginine, 2 | NMMA, 2)
Affinity DataKi:  2.90E+5nMAssay Description:Inhibition assay using DDAH-1 and nNOS.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
The University of Texas

LigandPNGBDBM92900(CHEMBL1835117 | L-Arginine, 2 | NMMA, 2)
Affinity DataKi:  1.20E+6nMAssay Description:Inhibition assay using DDAH-1 and nNOS.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
The University of Texas

LigandPNGBDBM92900(CHEMBL1835117 | L-Arginine, 2 | NMMA, 2)
Affinity DataKi:  1.40E+6nMAssay Description:Inhibition assay using DDAH-1 and nNOS.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
The University of Texas

LigandPNGBDBM92900(CHEMBL1835117 | L-Arginine, 2 | NMMA, 2)
Affinity DataAssay Description:Inhibition assay using DDAH-1 and nNOS.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
The University of Texas

LigandPNGBDBM92900(CHEMBL1835117 | L-Arginine, 2 | NMMA, 2)
Affinity DataAssay Description:Inhibition assay using DDAH-1 and nNOS.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
The University of Texas

LigandPNGBDBM92900(CHEMBL1835117 | L-Arginine, 2 | NMMA, 2)
Affinity DataIC50:  950nMAssay Description:Inhibition of human recombinant nNOS expressed in Sf9 cells assessed as inhibition of conversion of [3H]-L-arginine to [3H]-L-citrulline after 45 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Neuraxon

Curated by ChEMBL
LigandPNGBDBM92900(CHEMBL1835117 | L-Arginine, 2 | NMMA, 2)
Affinity DataIC50:  650nMAssay Description:Inhibition of human recombinant eNOS expressed in Sf9 cells assessed as inhibition of conversion of [3H]-L-arginine to [3H]-L-citrulline after 45 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Neuraxon

Curated by ChEMBL
LigandPNGBDBM92900(CHEMBL1835117 | L-Arginine, 2 | NMMA, 2)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of human recombinant iNOS expressed in Sf9 cells assessed as inhibition of conversion of [3H]-L-arginine to [3H]-L-citrulline after 45 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed