BDBM92913 Aryl 1-indanylketone, 2

SMILES Nc1cc(F)cc(-c2ccc(O)c(c2)C(=O)C2CCc3ccccc23)c1O

InChI Key InChIKey=VSEVSZZZZPLJHX-UHFFFAOYSA-N

Data  6 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 92913   

TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Max Planck Research

LigandPNGBDBM92913(Aryl 1-indanylketone, 2)
Affinity DataKi:  300nM ΔG°:  -8.30kcal/molepH: 7.8 T: 2°CAssay Description:PPIase activity assay were performed at 283 K in quartz cuvettes with a path length of 1 cm under vigorous stirring with a Hewlett-Packard 8453A UV-v...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
Max Planck Research

LigandPNGBDBM92913(Aryl 1-indanylketone, 2)
Affinity DataKi:  6.28E+3nM ΔG°:  -6.62kcal/molepH: 7.8 T: 2°CAssay Description:PPIase activity assay were performed at 283 K in quartz cuvettes with a path length of 1 cm under vigorous stirring with a Hewlett-Packard 8453A UV-v...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase B(Homo sapiens (Human))
Max Planck Research

LigandPNGBDBM92913(Aryl 1-indanylketone, 2)
Affinity DataKi:  1.20E+4nM ΔG°:  -6.26kcal/molepH: 7.8 T: 2°CAssay Description:PPIase activity assay were performed at 283 K in quartz cuvettes with a path length of 1 cm under vigorous stirring with a Hewlett-Packard 8453A UV-v...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase-like 1(Homo sapiens (Human))
Max Planck Research

LigandPNGBDBM92913(Aryl 1-indanylketone, 2)
Affinity DataKi: >1.00E+5nM ΔG°: >-5.09kcal/molepH: 7.8 T: 2°CAssay Description:PPIase activity assay were performed at 283 K in quartz cuvettes with a path length of 1 cm under vigorous stirring with a Hewlett-Packard 8453A UV-v...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase C(Homo sapiens (Human))
Max Planck Research

LigandPNGBDBM92913(Aryl 1-indanylketone, 2)
Affinity DataKi: >1.00E+5nM ΔG°: >-5.09kcal/molepH: 7.8 T: 2°CAssay Description:PPIase activity assay were performed at 283 K in quartz cuvettes with a path length of 1 cm under vigorous stirring with a Hewlett-Packard 8453A UV-v...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase H(Homo sapiens (Human))
Max Planck Research

LigandPNGBDBM92913(Aryl 1-indanylketone, 2)
Affinity DataKi: >1.00E+5nM ΔG°: >-5.09kcal/molepH: 7.8 T: 2°CAssay Description:PPIase activity assay were performed at 283 K in quartz cuvettes with a path length of 1 cm under vigorous stirring with a Hewlett-Packard 8453A UV-v...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase-like 1(Homo sapiens (Human))
Max Planck Research

LigandPNGBDBM92913(Aryl 1-indanylketone, 2)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PPIL1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Max Planck Research

LigandPNGBDBM92913(Aryl 1-indanylketone, 2)
Affinity DataIC50:  300nMAssay Description:Inhibition of CypA (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPeptidyl-prolyl cis-trans isomerase B(Homo sapiens (Human))
Max Planck Research

LigandPNGBDBM92913(Aryl 1-indanylketone, 2)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of CypB (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPeptidyl-prolyl cis-trans isomerase C(Homo sapiens (Human))
Max Planck Research

LigandPNGBDBM92913(Aryl 1-indanylketone, 2)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CypC (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
Max Planck Research

LigandPNGBDBM92913(Aryl 1-indanylketone, 2)
Affinity DataIC50:  6.28E+3nMAssay Description:Inhibition of CypD (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM92913(Aryl 1-indanylketone, 2)
Affinity DataIC50:  400nMAssay Description:Inhibition of Pin1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed