BDBM97233 CHEMBL9514::MLS001164242::N-[6-(2-thenoyl)-1H-benzimidazol-2-yl]carbamic acid methyl ester::N-[6-[oxo(thiophen-2-yl)methyl]-1H-benzimidazol-2-yl]carbamic acid methyl ester::Nocodazole::SMR000326904::cid_4122::methyl N-(6-thiophen-2-ylcarbonyl-1H-benzimidazol-2-yl)carbamate::methyl N-[6-(thiophene-2-carbonyl)-1H-benzimidazol-2-yl]carbamate::methyl [5-(2-thienylcarbonyl)-1H-benzimidazol-2-yl]carbamate

SMILES COC(=O)Nc1nc2ccc(cc2[nH]1)C(=O)c1cccs1

InChI Key InChIKey=KYRVNWMVYQXFEU-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 97233   

TargetTyrosine-protein kinase ABL1(Human)
Korea Institute of Science and Technology (Kaist)

Curated by ChEMBL
LigandPNGBDBM97233(cid_4122 | MLS001164242 | SMR000326904 | Nocodazol...)
Affinity DataIC50: 640nMAssay Description:Inhibition of breakpoint cluster region-Abelson tyrosine kinase T315I mutant (unknown origin) using [gamma-33P]ATP as substrate by radiometric kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetTubulin beta chain(Pig)
Westphalian Wilhelms-University

Curated by ChEMBL
LigandPNGBDBM97233(cid_4122 | MLS001164242 | SMR000326904 | Nocodazol...)
Affinity DataIC50: 760nMAssay Description:Inhibition of pig brain tubulin polymerization after 30 mins by turbidimetry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetTubulin beta chain(Pig)
Westphalian Wilhelms-University

Curated by ChEMBL
LigandPNGBDBM97233(cid_4122 | MLS001164242 | SMR000326904 | Nocodazol...)
Affinity DataIC50: 760nMAssay Description:In vitro inhibition of maximum porcine tubulin assembly rate after 20 min at 37 degrees CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetTubulin beta chain(Pig)
Westphalian Wilhelms-University

Curated by ChEMBL
LigandPNGBDBM97233(cid_4122 | MLS001164242 | SMR000326904 | Nocodazol...)
Affinity DataIC50: 760nMAssay Description:Inhibition of pig brain tubulin polymerization after 30 mins by turbidimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetTubulin beta chain(Pig)
Westphalian Wilhelms-University

Curated by ChEMBL
LigandPNGBDBM97233(cid_4122 | MLS001164242 | SMR000326904 | Nocodazol...)
Affinity DataIC50: 760nMAssay Description:Inhibition of porcine brain tubulin polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetTubulin beta chain(Pig)
Westphalian Wilhelms-University

Curated by ChEMBL
LigandPNGBDBM97233(cid_4122 | MLS001164242 | SMR000326904 | Nocodazol...)
Affinity DataIC50: 760nMAssay Description:Inhibition of pig brain tubulin polymerization after 30 mins by turbidimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetTubulin beta chain(Pig)
Westphalian Wilhelms-University

Curated by ChEMBL
LigandPNGBDBM97233(cid_4122 | MLS001164242 | SMR000326904 | Nocodazol...)
Affinity DataIC50: 760nMAssay Description:Inhibition of tubulin polymerization in porcine brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetTubulin beta chain(Pig)
Westphalian Wilhelms-University

Curated by ChEMBL
LigandPNGBDBM97233(cid_4122 | MLS001164242 | SMR000326904 | Nocodazol...)
Affinity DataIC50: 760nMAssay Description:Inhibition of pig tubulin polymerization determined after 45 mins at 37 degC by turbidimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetNuclear receptor subfamily 0 group B member 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM97233(cid_4122 | MLS001164242 | SMR000326904 | Nocodazol...)
Affinity DataIC50: 833nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay
TargetSimilar to alpha-tubulin isoform 1(Bovine)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM97233(cid_4122 | MLS001164242 | SMR000326904 | Nocodazol...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of bovine brain tubulin polymerization incubated for 90 mins by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetTubulin alpha-1A chain(Pig)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM97233(cid_4122 | MLS001164242 | SMR000326904 | Nocodazol...)
Affinity DataIC50: 5.70E+3nMAssay Description:Displacement of 5.8 uM [3H]-oncodazole from homogeneous tubulin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroidogenic factor 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM97233(cid_4122 | MLS001164242 | SMR000326904 | Nocodazol...)
Affinity DataIC50: 6.75E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay