BDBM97450 Aspartyl protease inhibitor, 16

SMILES COc1cc(Br)c(OC(=O)N(CC2C[NH2+]C[C@H]2CN(CCc2ccc(Cl)cc2Cl)C(=O)CCCc2ccccc2)Cc2ccccc2)cc1OC

InChI Key InChIKey=ZSKGVPQRVZKKRO-CYZZXXEPSA-O

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 97450   

TargetCathepsin D(Homo sapiens (Human))
Philipps-Universität Marburg

LigandPNGBDBM97450(Aspartyl protease inhibitor, 16)
Affinity DataIC50:  1.05E+3nMpH: 5.5Assay Description:Binding constants for inhibition of HIV protease were determined as previously described.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 (HIV-1))
Philipps-Universität Marburg

LigandPNGBDBM97450(Aspartyl protease inhibitor, 16)
Affinity DataIC50:  1.98E+4nMpH: 5.5Assay Description:Binding constants for inhibition of HIV protease were determined as previously described.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed