BDBM98181 US8486940, 13
SMILES CCCOc1ccc(cc1)[C@@H]1CNC(=O)N1c1ccc2nc[nH]c2c1
InChI Key InChIKey=XHIKZWOEFZENIX-SFHVURJKSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 98181
Affinity DataKi: 7.25E+3nM IC50: 3.02E+4nMAssay Description:Spectrophotometic Assay: This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spect...More data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Inhibition of human glutaminyl cyclase using L-glutamine-7-amido-4-methylcoumarin as substrate incubated for 10 mins in presence of pyroglutamyl pept...More data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged glutaminyl cyclase (Ala33 to Leu361 residues) expressed in baculovirus infected Sf21 insect ce...More data for this Ligand-Target Pair