BDBM98186 US8486940, 73::US9650362, 73

SMILES CCCOc1ccc(cc1)[C@H]1COC(=O)N1c1ccc2nc[nH]c2c1

InChI Key InChIKey=QZFGQBUTFFRJKB-GOSISDBHSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 98186   

TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM98186(US8486940, 73 | US9650362, 73)
Affinity DataKi:  33.6nM IC50:  170nMAssay Description:Spectrophotometic Assay: This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spect...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM98186(US8486940, 73 | US9650362, 73)
Affinity DataKi:  33.6nMAssay Description:All measurements were performed with a BioAssay Reader HTS-7000Plus for microplates (Perkin Elmer) at 30° C. QC activity was evaluated fluorometrical...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM98186(US8486940, 73 | US9650362, 73)
Affinity DataIC50:  170nMAssay Description:All measurements were performed with a BioAssay Reader HTS-7000Plus for microplates (Perkin Elmer) at 30° C. QC activity was evaluated fluorometrical...More data for this Ligand-Target Pair
In DepthDetails US Patent