BDBM98999 US8497265, 455

SMILES C1C(CN1c1ccc2ccccc2n1)Oc1nccnc1-c1cccnc1

InChI Key InChIKey=QPGDCWWRPYPOEH-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 98999   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM98999(US8497265, 455)Copy SMILESCopy InChI

Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of human PDE10A using FAM-cAMP substrate by TR-FRET progressive binding assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rattus norvegicus (rat))
Amgen

US Patent

LigandBDBM98999(US8497265, 455)Copy SMILESCopy InChI

Affinity DataIC50:  13.7nMAssay Description:Enzyme activity: An IMAP TR-FRET assay was used to analyze the enzyme activity (Molecular Devices Corp., Sunnyvale, Calif). More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails US Patent
Copy BDB DOI