Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with Target = 'Acetylcholine receptor subunit delta'
TargetAcetylcholine receptor subunit delta(Pacific electric ray)
Sibia Neurosciences

Curated by PDSP Ki Database
LigandPNGBDBM50369150(CHEMBL1788226)
Affinity DataEC50:  6.80E+4nMAssay Description:The compound was tested on recombinant human alpha3-beta4 cell lines of HUman embryonic kidney for nicotinic acetylcholine receptor agonist functiona...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit delta(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50211195(CHEMBL3944506)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at rat alpha1beta1deltaepsilon nAChR expressed in HEK293 cells for 2 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2018
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit delta(Pacific electric ray)
Sibia Neurosciences

Curated by PDSP Ki Database
LigandPNGBDBM50061562(CHEMBL335712 | Dihydro-Beta-erythroidine | (12R,13...)
Affinity DataEC50:  2.00E+6nMAssay Description:Compound was evaluated for functional potency and efficacy at human muscle type Nicotinic acetylcholine receptor in TE671 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit delta(Pacific electric ray)
Sibia Neurosciences

Curated by PDSP Ki Database
LigandPNGBDBM50056147(ABT-089 | 2-Methyl-3-((S)-1-pyrrolidin-2-ylmethoxy...)
Affinity DataEC50:  3.00E+4nMAssay Description:Compound was evaluated for functional potency and efficacy at human muscle type Nicotinic acetylcholine receptor in TE671 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit delta(Pacific electric ray)
Sibia Neurosciences

Curated by PDSP Ki Database
LigandPNGBDBM50143282((1R,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...)
Affinity DataEC50:  1.00E+4nMAssay Description:Compound was evaluated for functional potencies and efficacies at rat Nicotinic acetylcholine receptor subtype PC12 (ganglionic)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit delta(Pacific electric ray)
Sibia Neurosciences

Curated by PDSP Ki Database
LigandPNGBDBM50049756(A-84543 | 3-((S)-1-Methyl-pyrrolidin-2-ylmethoxy)-...)
Affinity DataEC50:  1.90E+4nMAssay Description:Compound was evaluated for functional potency and efficacy at human Nicotinic acetylcholine receptor ganglionic type on IMR-32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit delta(Pacific electric ray)
Sibia Neurosciences

Curated by PDSP Ki Database
LigandPNGBDBM50061563(4-Acetyl-1,1-dimethyl-1,2,3,6-tetrahydro-pyridiniu...)
Affinity DataEC50:  100nMAssay Description:Compound was evaluated for functional potency and efficacy at human muscle type Nicotinic acetylcholine receptor in TE671 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit delta(Pacific electric ray)
Sibia Neurosciences

Curated by PDSP Ki Database
LigandPNGBDBM10759(2-acetoxyethyl(trimethyl)ammonium;perchlorate | 2-...)
Affinity DataEC50:  4.00E+4nMAssay Description:Compound was evaluated for functional potencies and efficacies at rat Nicotinic acetylcholine receptor subtype PC12 (ganglionic)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit delta(Pacific electric ray)
Sibia Neurosciences

Curated by PDSP Ki Database
LigandPNGBDBM50035398(ABT-418 | (S)-1-Methyl-2-(3-methyl-isoxazol-5-yl)-...)
Affinity DataEC50:  4.11E+5nMAssay Description:Compound was evaluated for functional potency and efficacy at human muscle type Nicotinic acetylcholine receptor in TE671 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit delta(Pacific electric ray)
Sibia Neurosciences

Curated by PDSP Ki Database
LigandPNGBDBM50049757((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....)
Affinity DataEC50:  100nMAssay Description:Compound was evaluated for functional potencies and efficacies at rat Nicotinic acetylcholine receptor subtype PC12 (ganglionic)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit delta(Pacific electric ray)
Sibia Neurosciences

Curated by PDSP Ki Database
LigandPNGBDBM50061561(Methyl-((E)-4-pyridin-3-yl-but-3-enyl)-amine | N-m...)
Affinity DataEC50: >1.00E+6nMAssay Description:Compound was evaluated for functional potencies and efficacies at rat Nicotinic acetylcholine receptor subtype PC12 (ganglionic)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit delta(Pacific electric ray)
Sibia Neurosciences

Curated by PDSP Ki Database
LigandPNGBDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)
Affinity DataEC50:  2.00E+4nMAssay Description:Compound was evaluated for functional potencies and efficacies at rat Nicotinic acetylcholine receptor subtype PC12 (ganglionic)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit delta(Pacific electric ray)
Sibia Neurosciences

Curated by PDSP Ki Database
LigandPNGBDBM50369150(CHEMBL1788226)
Affinity DataEC50:  3.10E+4nMAssay Description:The compound was tested on recombinant human alpha4-beta4 cell lines of HUman embryonic kidney for nicotinic acetylcholine receptor agonist functiona...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit delta(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50547502(CHEMBL4793300)
Affinity DataIC50: 0.184nMAssay Description:Inhibition of rat alpha1beta1epsilondelta expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced channel current respons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit delta(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50111638(N-[(S)-1-(11-Amino-undecylcarbamoyl)-2-(4-hydroxy-...)
Affinity DataIC50: 460nMAssay Description:Compound was evaluated for inhibitory activity against human embryonic muscle type Nicotinic acetylcholine receptor specifically delta-subunit expres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit delta(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50111638(N-[(S)-1-(11-Amino-undecylcarbamoyl)-2-(4-hydroxy-...)
Affinity DataIC50: 580nMAssay Description:Compound was evaluated for inhibitory activity against human embryonic muscle type Nicotinic acetylcholine receptor specifically delta-subunit expres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit delta(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50094299(N-[(S)-1-(12-Amino-dodecylcarbamoyl)-2-(4-hydroxy-...)
Affinity DataIC50: 930nMAssay Description:Compound was evaluated for inhibitory activity against human embryonic muscle type Nicotinic acetylcholine receptor specifically delta-subunit expres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit delta(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50094299(N-[(S)-1-(12-Amino-dodecylcarbamoyl)-2-(4-hydroxy-...)
Affinity DataIC50: 1.53E+3nMAssay Description:Compound was evaluated for inhibitory activity against human embryonic muscle type Nicotinic acetylcholine receptor specifically delta-subunit expres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit delta(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50111636(N-[(S)-1-(8-Amino-octylcarbamoyl)-2-(4-hydroxy-phe...)
Affinity DataIC50: 5.03E+3nMAssay Description:Compound was evaluated for inhibitory activity against human embryonic muscle type Nicotinic acetylcholine receptor specifically delta-subunit expres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit delta(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50111639(N-[(S)-1-(7-Amino-heptylcarbamoyl)-2-(4-hydroxy-ph...)
Affinity DataIC50: 5.44E+3nMAssay Description:Compound was evaluated for inhibitory activity against human embryonic muscle type Nicotinic acetylcholine receptor specifically delta-subunit expres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit delta(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50111640(N-[(S)-1-(10-Amino-decylcarbamoyl)-2-(4-hydroxy-ph...)
Affinity DataIC50: 8.66E+3nMAssay Description:Compound was evaluated for inhibitory activity against human embryonic muscle type Nicotinic acetylcholine receptor specifically delta-subunit expres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit delta(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50111636(N-[(S)-1-(8-Amino-octylcarbamoyl)-2-(4-hydroxy-phe...)
Affinity DataIC50: 9.76E+3nMAssay Description:Compound was evaluated for inhibitory activity against human embryonic muscle type Nicotinic acetylcholine receptor specifically delta-subunit expres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit delta(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50111639(N-[(S)-1-(7-Amino-heptylcarbamoyl)-2-(4-hydroxy-ph...)
Affinity DataIC50: 1.05E+4nMAssay Description:Compound was evaluated for inhibitory activity against human embryonic muscle type Nicotinic acetylcholine receptor specifically delta-subunit expres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit delta(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50111637(N-[(S)-1-(9-Amino-nonylcarbamoyl)-2-(4-hydroxy-phe...)
Affinity DataIC50: 1.33E+4nMAssay Description:Compound was evaluated for inhibitory activity against human embryonic muscle type Nicotinic acetylcholine receptor specifically delta-subunit expres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit delta(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50111637(N-[(S)-1-(9-Amino-nonylcarbamoyl)-2-(4-hydroxy-phe...)
Affinity DataIC50: 1.51E+4nMAssay Description:Compound was evaluated for inhibitory activity against human embryonic muscle type Nicotinic acetylcholine receptor specifically delta-subunit expres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit delta(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50094298(N-[1-{3-[4-(3-Amino-propylamino)-butylamino]-propy...)
Affinity DataIC50: 7.50E+4nMAssay Description:Compound was evaluated for inhibitory activity against human embryonic muscle type Nicotinic acetylcholine receptor specifically delta-subunit expres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit delta(Pacific electric ray)
Sibia Neurosciences

Curated by PDSP Ki Database
LigandPNGBDBM50049757((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....)
Affinity DataKi:  0.100nMAssay Description:Agonist activity against Nicotinic acetylcholine receptor (nAchR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed