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Report error Found 4017 Enz. Inhib. hit(s) with Target = 'Aurora kinase B'
TargetAurora kinase B(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50460772(CHEMBL4225923)
Affinity DataKd:  0.0100nMAssay Description:Binding affinity to Aurora B (unknown origin) after 45 mins by fluorescence-based thermal stability shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetAurora kinase B/Inner centromere protein(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM209861(TAK-901 | 5-(3-ethylsulfonylphenyl)-3,8-dimethyl-N...)
Affinity DataKi:  0.0200nMAssay Description:Inhibition of Aurora B/INCENP (unknown origin) assessed as affinity constant pre-incubated for 1 hr followed by FL-PKAtide substrate and ATP additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM116714(US8637532, 423)
Affinity DataIC50: 0.0420nMAssay Description:The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetAurora kinase B(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM116779(US8637532, 496)
Affinity DataIC50: 0.0450nMAssay Description:The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetAurora kinase B(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM116717(US8637532, 426)
Affinity DataIC50: 0.0460nMAssay Description:The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetAurora kinase B(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM116823(US8637532, 549)
Affinity DataIC50: 0.0600nMAssay Description:The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetAurora kinase B(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM116924(US8637532, 651)
Affinity DataIC50: 0.0610nMAssay Description:The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetAurora kinase B(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM116959(US8637532, 686)
Affinity DataIC50: 0.0890nMAssay Description:The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetAurora kinase B(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50460773(CHEMBL4227082)
Affinity DataKd:  0.100nMAssay Description:Binding affinity to Aurora B (unknown origin) after 45 mins by fluorescence-based thermal stability shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM116640(US8637532, 339)
Affinity DataIC50: 0.170nMAssay Description:The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetAurora kinase B(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM116944(US8637532, 671)
Affinity DataIC50: 0.180nMAssay Description:The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetAurora kinase B(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM116868(US8637532, 594)
Affinity DataIC50: 0.180nMAssay Description:The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetAurora kinase B(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM116931(US8637532, 658)
Affinity DataIC50: 0.200nMAssay Description:The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetAurora kinase B(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50362061(CHEMBL1940103)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of aurora-BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM116926(US8637532, 653)
Affinity DataIC50: 0.210nMAssay Description:The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetAurora kinase B(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM116988(US8637532, 715)
Affinity DataIC50: 0.220nMAssay Description:The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetAurora kinase B(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM116420(US8637532, 101)
Affinity DataIC50: 0.240nMAssay Description:The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetAurora kinase B(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM116553(US8637532, 244)
Affinity DataIC50: 0.25nMAssay Description:The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetAurora kinase B(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM116771(US8637532, 488)
Affinity DataIC50: 0.260nMAssay Description:The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetAurora kinase B(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM116690(US8637532, 394)
Affinity DataIC50: 0.270nMAssay Description:The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetAurora kinase B(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50503749(CHEMBL4455202)
Affinity DataIC50: 0.290nMAssay Description:Inhibition of Aurora B (unknown origin) using kemptide acetate salt as substrate after 30 mins by kinase-Glo luminescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50056188(CHEMBL3329654)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of Aurora B (unknown origin) using HLRRASLG substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM116825(US8637532, 551)
Affinity DataIC50: 0.300nMAssay Description:The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetAurora kinase B(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM116673(US8637532, 375)
Affinity DataIC50: 0.300nMAssay Description:The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetAurora kinase B(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM116939(US8637532, 666)
Affinity DataIC50: 0.310nMAssay Description:The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetAurora kinase B(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50565411(CHEMBL4799738)
Affinity DataIC50: 0.316nMAssay Description:Inhibition of recombinant human full-length His-tagged Aurora B expressed in baculovirus expression system using 5-FAM-LRRASLG-CONH2 as substrate pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM116615(US8637532, 309)
Affinity DataIC50: 0.320nMAssay Description:The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetAurora kinase B(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50466808(AZD-1152-HQPA | Barasertib)
Affinity DataIC50: 0.326nMAssay Description:Inhibition of recombinant human full-length His-tagged Aurora B expressed in baculovirus expression system using 5-FAM-LRRASLG-CONH2 as substrate pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM116918(US8637532, 645)
Affinity DataIC50: 0.330nMAssay Description:The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetAurora kinase B(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50565427(CHEMBL4784002)
Affinity DataIC50: 0.336nMAssay Description:Inhibition of recombinant human full-length His-tagged Aurora B expressed in baculovirus expression system using 5-FAM-LRRASLG-CONH2 as substrate pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50503741(CHEMBL4443125)
Affinity DataIC50: 0.340nMAssay Description:Inhibition of Aurora B (unknown origin) using kemptide acetate salt as substrate after 30 mins by kinase-Glo luminescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM116573(US8637532, 265)
Affinity DataIC50: 0.350nMAssay Description:The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetAurora kinase B(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM116559(US8637532, 250)
Affinity DataIC50: 0.350nMAssay Description:The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetAurora kinase B(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM116387(US8637532, 68)
Affinity DataIC50: 0.350nMAssay Description:The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetAurora kinase B(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50241089(CHEMBL415049 | AZD1152, 33 | 2-(ethyl(3-(4-(5-(2-(...)
Affinity DataKi:  0.359nMAssay Description:Inhibition of human aurora BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetAurora kinase B(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50241089(CHEMBL415049 | AZD1152, 33 | 2-(ethyl(3-(4-(5-(2-(...)
Affinity DataKi:  0.360nMAssay Description:Binding affinity to Aurora B (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetAurora kinase B(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50466808(AZD-1152-HQPA | Barasertib)
Affinity DataIC50: 0.370nMAssay Description:Inhibition of Aurora B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetAurora kinase B(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50241089(CHEMBL415049 | AZD1152, 33 | 2-(ethyl(3-(4-(5-(2-(...)
Affinity DataKi:  0.370nMAssay Description:Inhibition of aurora B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50241089(CHEMBL415049 | AZD1152, 33 | 2-(ethyl(3-(4-(5-(2-(...)
Affinity DataIC50: 0.370nMAssay Description:Inhibition of Aurora B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2017
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50543551(CHEMBL4633715)
Affinity DataIC50: 0.370nMAssay Description:Inhibition of Aurora B in human SW620 cells assessed as reduction in histone H3 phosphorylation on Ser10 by Alexafluor-488 goat anti-rabbit antibody/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50466808(AZD-1152-HQPA | Barasertib)
Affinity DataIC50: 0.370nMAssay Description:Inhibition of recombinant aurora B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50466808(AZD-1152-HQPA | Barasertib)
Affinity DataIC50: 0.370nMAssay Description:Inhibition of Aurora B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50466808(AZD-1152-HQPA | Barasertib)
Affinity DataIC50: 0.370nMAssay Description:Inhibition of Aurora B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50241089(CHEMBL415049 | AZD1152, 33 | 2-(ethyl(3-(4-(5-(2-(...)
Affinity DataIC50: 0.370nMAssay Description:Inhibition of Aurora B kinase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetAurora kinase B(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50315769(GSK-1070916 | 4-[3-(4-N,N-Dimethylcarbamylaminophe...)
Affinity DataKi:  0.380nMAssay Description:Competitive inhibition of Aurora B ATP binding siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50315769(GSK-1070916 | 4-[3-(4-N,N-Dimethylcarbamylaminophe...)
Affinity DataKi:  0.380nMAssay Description:Competitive inhibition of human Aurora B ATP binding site by rapid dilution methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetAurora kinase B/Inner centromere protein(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50315769(GSK-1070916 | 4-[3-(4-N,N-Dimethylcarbamylaminophe...)
Affinity DataKi:  0.380nMAssay Description:Inhibition of human Aurora B/INCENP pre-incubated for 30 mins before 5-FAM-PKAtide substrate addition and measured after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM116821(US8637532, 547)
Affinity DataIC50: 0.380nMAssay Description:The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetAurora kinase B(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM116934(US8637532, 661)
Affinity DataIC50: 0.380nMAssay Description:The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetAurora kinase B(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM116932(US8637532, 659)
Affinity DataIC50: 0.380nMAssay Description:The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

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