Report error Found 962 Enz. Inhib. hit(s) with Target = 'Breakpoint cluster region protein'
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataEC50: 3nMAssay Description:Inhibition of wild-type Bcr-Abl autophosphorylation (unknown origin) expressed in mouse BA/F3 cells for 3 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataEC50: 1nMAssay Description:Inhibition of wild-type Bcr-Abl autophosphorylation (unknown origin) expressed in mouse BA/F3 cells for 3 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataEC50: 20nMAssay Description:Inhibition of Bcr-Abl T315I mutant (unknown origin) autophosphorylation expressed in mouse BA/F3 cells for 3 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataEC50: 25nMAssay Description:Inhibition of Bcr-Abl T315I mutant (unknown origin) autophosphorylation expressed in mouse BA/F3 cells for 3 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataEC50: <10nMAssay Description:Inhibition of BCR/ABL T315I mutant (unknown origin) expressed in mouse BAF3 cells assessed as inhibition of STAT5 phosphorylation after 1 hr by immun...More data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataEC50: <10nMAssay Description:Inhibition of BCR/ABL in human K562 cells assessed as inhibition of BCR/ABL autophosphorylation at Y245 site after 1 hr by immunoblotting analysisMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataEC50: <30nMAssay Description:Inhibition of BCR/ABL in human KU812 cells assessed as inhibition of BCR/ABL autophosphorylation at Y245 site after 1 hr by immunoblotting analysisMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataEC50: <10nMAssay Description:Inhibition of BCR/ABL T315I mutant (unknown origin) expressed in mouse BAF3 cells assessed as inhibition of BCR/ABL T315I mutant autophosphorylation ...More data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataEC50: <10nMAssay Description:Inhibition of BCR/ABL T315I mutant (unknown origin) expressed in mouse BAF3 cells assessed as inhibition of ErK phosphorylation after 1 hr by immunob...More data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataEC50: <10nMAssay Description:Inhibition of BCR/ABL in human MEG01 cells assessed as inhibition of BCR/ABL autophosphorylation at Y245 site after 1 hr by immunoblotting analysisMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataEC50: <10nMAssay Description:Inhibition of BCR/ABL T315I mutant (unknown origin) expressed in mouse BAF3 cells assessed as inhibition of CrkL phosphorylation after 1 hr by immuno...More data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataKd: 0.450nMAssay Description:Binding affinity to BCR-ABL1 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataEC50: 400nMAssay Description:Inhibition of Bcr-Abl in mouse BA/F3 cellsMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataEC50: 7.15E+3nMAssay Description:Inhibition of Bcr-Abl in mouse BA/F3 cellsMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataEC50: 6.89E+3nMAssay Description:Inhibition of Bcr-Abl in mouse BA/F3 cellsMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataEC50: 690nMAssay Description:Inhibition of Bcr-Abl in mouse BA/F3 cellsMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataEC50: 160nMAssay Description:Inhibition of Bcr-Abl in mouse BA/F3 cellsMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataEC50: 2.96E+3nMAssay Description:Inhibition of Bcr-Abl in mouse BA/F3 cellsMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataEC50: 6.92E+3nMAssay Description:Inhibition of Bcr-Abl in mouse BA/F3 cellsMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataEC50: 1.30E+3nMAssay Description:Inhibition of Bcr-Abl in mouse BA/F3 cellsMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataEC50: 1.32E+3nMAssay Description:Inhibition of Bcr-Abl in mouse BA/F3 cellsMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataEC50: 1.20E+3nMAssay Description:Inhibition of Bcr-Abl in mouse BA/F3 cellsMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataEC50: 160nMAssay Description:Inhibition of Bcr-Abl in mouse BA/F3 cellsMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataEC50: 2.20E+3nMAssay Description:Inhibition of Bcr-Abl in mouse BA/F3 cellsMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataEC50: 4.34E+3nMAssay Description:Inhibition of Bcr-Abl in mouse BA/F3 cellsMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of Bcr-Abl in mouse BA/F3 cellsMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataEC50: 1.70E+3nMAssay Description:Inhibition of Bcr-Abl in mouse BA/F3 cellsMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataKd: 92nMAssay Description:Inhibition of Bcr-Abl in mouse BA/F3 cellsMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataKd: 114nMAssay Description:Inhibition of Bcr-Abl in mouse BA/F3 cellsMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataKd: 43nMAssay Description:Inhibition of Bcr-Abl in mouse BA/F3 cellsMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataKd: 57nMAssay Description:Inhibition of Bcr-Abl in mouse BA/F3 cellsMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataKd: 46nMAssay Description:Inhibition of Bcr-Abl in mouse BA/F3 cellsMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataKd: 598nMAssay Description:Inhibition of Bcr-Abl in mouse BA/F3 cellsMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataKd: 394nMAssay Description:Inhibition of Bcr-Abl in mouse BA/F3 cellsMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataKd: 526nMAssay Description:Inhibition of Bcr-Abl in mouse BA/F3 cellsMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataEC50: 720nMAssay Description:Inhibition of Bcr-Abl in mouse BA/F3 cellsMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataEC50: 4.47E+3nMAssay Description:Inhibition of Bcr-Abl in mouse BA/F3 cellsMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataEC50: 1.80E+3nMAssay Description:Inhibition of Bcr-Abl in mouse BA/F3 cellsMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataEC50: 1.66E+3nMAssay Description:Inhibition of Bcr-Abl in mouse BA/F3 cellsMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataEC50: 5.00E+3nMAssay Description:Inhibition of Bcr-Abl in mouse BA/F3 cellsMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataEC50: 2.92E+3nMAssay Description:Inhibition of Bcr-Abl in mouse BA/F3 cellsMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataEC50: 140nMAssay Description:Inhibition of Bcr-Abl in mouse BA/F3 cellsMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataEC50: 480nMAssay Description:Inhibition of Bcr-Abl in mouse BA/F3 cellsMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of Bcr-Abl in mouse BA/F3 cellsMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataEC50: 470nMAssay Description:Inhibition of Bcr-Abl in mouse BA/F3 cellsMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataEC50: 580nMAssay Description:Inhibition of Bcr-Abl in mouse BA/F3 cellsMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataEC50: 390nMAssay Description:Inhibition of Bcr-Abl in mouse BA/F3 cellsMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataEC50: 330nMAssay Description:Inhibition of Bcr-Abl in mouse BA/F3 cellsMore data for this Ligand-Target Pair





































