Compile Data Set for Download or QSAR
Report error Found 3655 Enz. Inhib. hit(s) with Target = 'Cholecystokinin'
TargetCholecystokinin receptor type A(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50329178((S)-3-(3-(1-(2-(isopropyl(phenyl)amino)-2-oxoethyl...)
Affinity DataEC50:  0.00200nMAssay Description:Activity at CCK1R (unknown origin) expressed in CHO cells assessed as CCK EC50 measured as intracellular calcium responses at 0.316 nM (Rvb = 7 to 14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
LigandPNGBDBM21147((3S)-3-[(2S)-2-[(2S)-2-{2-[(2S)-2-[(2S)-2-[(3S)-3-...)
Affinity DataEC50:  0.00900nMAssay Description:Ability to stimulate intracellular calcium response was determined using CCK receptor-bearing chinese hamster ovary cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50245192(3-((S)-4-(1-(3-ethoxyphenyl)-2-(2-fluoro-4-methylp...)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of human CCK1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50329178((S)-3-(3-(1-(2-(isopropyl(phenyl)amino)-2-oxoethyl...)
Affinity DataEC50:  0.0100nMAssay Description:Activity at CCK1R (unknown origin) expressed in CHO cells assessed as CCK EC50 measured as intracellular calcium responses at 0.1 nM (Rvb = 7 to 14 p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50329178((S)-3-(3-(1-(2-(isopropyl(phenyl)amino)-2-oxoethyl...)
Affinity DataEC50:  0.0130nMAssay Description:Activity at CCK1R (unknown origin) expressed in CHO cells assessed as CCK EC50 measured as intracellular calcium responses at 0.01 nM (Rvb = 7 to 14 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50074832(CHEMBL156605)
Affinity DataEC50:  0.0140nMAssay Description:Activity at CCK1R (unknown origin) expressed in CHO cells assessed as CCK EC50 measured as intracellular calcium responses at 100 nM (Rvb = 7 to 14 p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50245186(3-((S)-4-(1-(3-ethoxyphenyl)-2-p-tolyl-1H-imidazol...)
Affinity DataIC50: 0.0160nMAssay Description:Inhibition of human CCK1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50245205(2-((S)-1-(1-(3-ethoxyphenyl)-2-p-tolyl-1H-imidazol...)
Affinity DataIC50: 0.0180nMAssay Description:Inhibition of human CCK1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50074832(CHEMBL156605)
Affinity DataEC50:  0.0190nMAssay Description:Activity at CCK1R (unknown origin) expressed in CHO cells assessed as CCK EC50 measured as intracellular calcium responses at 10 nM (Rvb = 7 to 14 pM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Rat)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50089269(N-(1-Carbamoyl-2-phenyl-ethyl)-3-{2-[3-(1H-indol-3...)
Affinity DataKi:  0.0200nMAssay Description:Inhibition of [125I]BH-CCK-8 binding to Cholecystokinin type A receptor of rat pancreatic tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50072419(2-[2,4-Dioxo-5-phenyl-3-(3-phenyl-ureido)-2,3,4,5-...)
Affinity DataEC50:  0.0200nMAssay Description:Activity at CCK1R (unknown origin) expressed in CHO cells assessed as CCK EC50 measured as intracellular calcium responses at 10 nM (Rvb = 7 to 14 pM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50061829((R)-N-((S)-1-Carbamoyl-2-phenyl-ethyl)-3-({(S)-2-[...)
Affinity DataEC50:  0.0251nMAssay Description:Agonist activity at human CCK1R expressed in human 1321N1 cells assessed as IP1 accumulation after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Rat)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50061828(N-(1-Carbamoyl-2-phenyl-ethyl)-3-({2-[3-(1H-indol-...)
Affinity DataKi:  0.0300nMAssay Description:Inhibition of [125I]BH-CCK-8 binding to Cholecystokinin type A receptor of rat pancreatic tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Rat)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50061829((R)-N-((S)-1-Carbamoyl-2-phenyl-ethyl)-3-({(S)-2-[...)
Affinity DataKi:  0.0300nMAssay Description:Binding affinity for Cholecystokinin type A receptor using [125I]BH-CCK-8 in rat pancreatic tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Rat)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50061828(N-(1-Carbamoyl-2-phenyl-ethyl)-3-({2-[3-(1H-indol-...)
Affinity DataKi:  0.0300nMAssay Description:Binding affinity for Cholecystokinin type A receptor using [125I]BH-CCK-8 in rat pancreatic tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50263229(CHEMBL505225 | CHEMBL505969 | 3-(4-(1-(2,3-dihydro...)
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of human CCK1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50263230(3-(4-(1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2-(2...)
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of human CCK1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50245189(3-((R)-3-(acetamidomethyl)-4-(1-(3-ethoxyphenyl)-2...)
Affinity DataEC50:  0.0330nMAssay Description:Agonist activity at human CCK1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50245188(3-((S)-3-((carboxymethoxy)methyl)-4-(1-(3-ethoxyph...)
Affinity DataEC50:  0.0340nMAssay Description:Agonist activity at human CCK1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50343722(3-(4-(5-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-4-(2...)
Affinity DataIC50: 0.0340nMAssay Description:Displacement of [I125]-CCK8 from human CCK1 receptor expressed in CHO Flip cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50245192(3-((S)-4-(1-(3-ethoxyphenyl)-2-(2-fluoro-4-methylp...)
Affinity DataEC50:  0.0340nMAssay Description:Agonist activity at mouse CCK1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50074832(CHEMBL156605)
Affinity DataEC50:  0.0390nMAssay Description:Activity at CCK1R (unknown origin) expressed in CHO cells assessed as CCK EC50 measured as intracellular calcium responses at 1000 nM (Rvb = 7 to 14 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50245195(2-(((R)-1-(1-(3-ethoxyphenyl)-2-p-tolyl-1H-imidazo...)
Affinity DataIC50: 0.0390nMAssay Description:Inhibition of human CCK1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50245187(CHEMBL504861 | CHEMBL446789 | 3-(4-(1-(3-ethoxyphe...)
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of human CCK1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50245182(3-((S)-3-(acetamidomethyl)-4-(1-(3-ethoxyphenyl)-2...)
Affinity DataEC50:  0.0400nMAssay Description:Agonist activity at human CCK1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50517344(CHEMBL4526455)
Affinity DataIC50: 0.0407nMAssay Description:Displacement of [125I]-CCK-8 from human CCK1R expressed in human 1321N1 cell membranes after 2 hrs by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50245188(3-((S)-3-((carboxymethoxy)methyl)-4-(1-(3-ethoxyph...)
Affinity DataIC50: 0.0410nMAssay Description:Inhibition of human CCK1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50517358(CHEMBL4585323)
Affinity DataIC50: 0.0427nMAssay Description:Displacement of [125I]-CCK-8 from human CCK1R expressed in human 1321N1 cell membranes after 2 hrs by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM21147((3S)-3-[(2S)-2-[(2S)-2-{2-[(2S)-2-[(2S)-2-[(3S)-3-...)
Affinity DataEC50:  0.0437nMAssay Description:Agonist activity at human CCK1R expressed in human 1321N1 cells assessed as IP1 accumulation after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50061829((R)-N-((S)-1-Carbamoyl-2-phenyl-ethyl)-3-({(S)-2-[...)
Affinity DataIC50: 0.0447nMAssay Description:Displacement of [125I]-CCK-8 from human CCK1R expressed in human 1321N1 cell membranes after 2 hrs by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50263226(CHEMBL506201 | CHEMBL498942 | 3-(4-(1-(3-ethoxyphe...)
Affinity DataEC50:  0.0480nMAssay Description:Agonist activity against human CCK1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Rat)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50003666(3-[2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Affinity DataIC50: 0.0500nMAssay Description:Inhibitory activity against cholecystokinin type A receptor from rat pancreas binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Rat)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50003669(CHEMBL411079 | Ac-Tyr(SO3H)-Met-Gly-Trp-Met-R-Dtc-...)
Affinity DataIC50: 0.0500nMAssay Description:Concentration inhibiting [3H]propionyl-CCK-8 binding to cholecystokinin type A receptor of rat pancreatic membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholecystokinin(Pig)
Merck Sharp & Dohme Research Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM81963(CHOLECYSTOKININ | CCK33 | CAS_9011-97-6 | CCK)
Affinity DataKi:  0.0500nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2011
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Rat)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50089268(N-(1-Carbamoyl-2-phenyl-ethyl)-3-{2-[2-(2-{2-[2-(4...)
Affinity DataKi:  0.0500nMAssay Description:Inhibition of [125I]BH-CCK-8 binding to Cholecystokinin type A receptor of rat pancreatic tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50517353(CHEMBL4525615)
Affinity DataIC50: 0.0501nMAssay Description:Displacement of [125I]-CCK-8 from human CCK1R expressed in human 1321N1 cell membranes after 2 hrs by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50072419(2-[2,4-Dioxo-5-phenyl-3-(3-phenyl-ureido)-2,3,4,5-...)
Affinity DataEC50:  0.0510nMAssay Description:Activity at CCK1R (unknown origin) expressed in CHO cells assessed as CCK EC50 measured as intracellular calcium responses at 100 nM (Rvb = 7 to 14 p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50245201(3-(((S)-1-(1-(3-ethoxyphenyl)-2-p-tolyl-1H-imidazo...)
Affinity DataIC50: 0.0520nMAssay Description:Inhibition of human CCK1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50517333(CHEMBL4440419)
Affinity DataIC50: 0.0525nMAssay Description:Displacement of [125I]-CCK-8 from human CCK1R expressed in human 1321N1 cell membranes after 2 hrs by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50263227(3-(4-(2-(2,4-difluorophenyl)-1-(3-ethoxyphenyl)-1H...)
Affinity DataEC50:  0.0530nMAssay Description:Agonist activity against human CCK1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50245186(3-((S)-4-(1-(3-ethoxyphenyl)-2-p-tolyl-1H-imidazol...)
Affinity DataEC50:  0.0530nMAssay Description:Agonist activity at human CCK1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50245187(CHEMBL504861 | CHEMBL446789 | 3-(4-(1-(3-ethoxyphe...)
Affinity DataEC50:  0.0550nMAssay Description:Agonist activity at human CCK1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50245187(CHEMBL504861 | CHEMBL446789 | 3-(4-(1-(3-ethoxyphe...)
Affinity DataEC50:  0.0560nMAssay Description:Agonist activity against human CCK1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50245189(3-((R)-3-(acetamidomethyl)-4-(1-(3-ethoxyphenyl)-2...)
Affinity DataIC50: 0.0580nMAssay Description:Inhibition of human CCK1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50245187(CHEMBL504861 | CHEMBL446789 | 3-(4-(1-(3-ethoxyphe...)
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of human CCK1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50517373(CHEMBL4514283)
Affinity DataIC50: 0.0603nMAssay Description:Displacement of [125I]-CCK-8 from human CCK1R expressed in human 1321N1 cell membranes after 2 hrs by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50517380(CHEMBL4464703)
Affinity DataEC50:  0.0603nMAssay Description:Agonist activity at human CCK1R expressed in human 1321N1 cells assessed as IP1 accumulation after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50343721(3-(4-(4-(2-fluoro-4-methylphenyl)-5-(4-methoxyphen...)
Affinity DataEC50:  0.0630nMAssay Description:Agonist activity at human CCK1 receptor expressed in CHO Flip cells assessed as increase of radio labeled inositol phosphate accumulation by Wallac m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50517378(CHEMBL4440303)
Affinity DataIC50: 0.0631nMAssay Description:Displacement of [125I]-CCK-8 from human CCK1R expressed in human 1321N1 cell membranes after 2 hrs by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50517375(CHEMBL4483457)
Affinity DataIC50: 0.0646nMAssay Description:Displacement of [125I]-CCK-8 from human CCK1R expressed in human 1321N1 cell membranes after 2 hrs by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
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