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Found 12 Enz. Inhib. hit(s) with Target = 'Cholecystokinin receptor type A' and Ligand = 'BDBM50329178'
TargetCholecystokinin receptor type A(RAT)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50329178((S)-3-(3-(1-(2-(isopropyl(phenyl)amino)-2-oxoethyl...)
Affinity DataIC50:  52.6nMAssay Description:Displacement of [125I]CCK8 from rat CCK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50329178((S)-3-(3-(1-(2-(isopropyl(phenyl)amino)-2-oxoethyl...)
Affinity DataIC50:  105nMAssay Description:Displacement of [125I]CCK from CCK1R (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50329178((S)-3-(3-(1-(2-(isopropyl(phenyl)amino)-2-oxoethyl...)
Affinity DataIC50:  126nMAssay Description:Compound was tested in vitro for its ability to displace [125I]Bolton-Hunter CCK-8 from membrane preparation isolated from CHO-KI cells stably transf...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50329178((S)-3-(3-(1-(2-(isopropyl(phenyl)amino)-2-oxoethyl...)
Affinity DataIC50:  128nMAssay Description:Displacement of [125I]BDZ1 from CCK1R (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50329178((S)-3-(3-(1-(2-(isopropyl(phenyl)amino)-2-oxoethyl...)
Affinity DataIC50:  131nMAssay Description:Displacement of [125I]CCK8 from human CCK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50329178((S)-3-(3-(1-(2-(isopropyl(phenyl)amino)-2-oxoethyl...)
Affinity DataEC50:  63.8nMAssay Description:Agonist activity at rat CCK1 receptor expressed in CHO cells assessed as induction of calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50329178((S)-3-(3-(1-(2-(isopropyl(phenyl)amino)-2-oxoethyl...)
Affinity DataEC50:  283nMAssay Description:Agonist activity at human CCK1 receptor expressed in CHO cells assessed as induction of calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50329178((S)-3-(3-(1-(2-(isopropyl(phenyl)amino)-2-oxoethyl...)
Affinity DataEC50:  0.190nMAssay Description:Activity at CCK1R (unknown origin) expressed in CHO cells assessed as CCK EC50 measured as intracellular calcium responses at 1 nM (Rvb = 7 to 14 pM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50329178((S)-3-(3-(1-(2-(isopropyl(phenyl)amino)-2-oxoethyl...)
Affinity DataEC50:  0.00200nMAssay Description:Activity at CCK1R (unknown origin) expressed in CHO cells assessed as CCK EC50 measured as intracellular calcium responses at 0.316 nM (Rvb = 7 to 14...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50329178((S)-3-(3-(1-(2-(isopropyl(phenyl)amino)-2-oxoethyl...)
Affinity DataEC50:  0.0100nMAssay Description:Activity at CCK1R (unknown origin) expressed in CHO cells assessed as CCK EC50 measured as intracellular calcium responses at 0.1 nM (Rvb = 7 to 14 p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50329178((S)-3-(3-(1-(2-(isopropyl(phenyl)amino)-2-oxoethyl...)
Affinity DataEC50:  0.0130nMAssay Description:Activity at CCK1R (unknown origin) expressed in CHO cells assessed as CCK EC50 measured as intracellular calcium responses at 0.01 nM (Rvb = 7 to 14 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50329178((S)-3-(3-(1-(2-(isopropyl(phenyl)amino)-2-oxoethyl...)
Affinity DataEC50:  0.800nMAssay Description:Activity at CCK1R (unknown origin) expressed in CHO cells assessed as stimulation of intracellular calcium responsesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed