Compile Data Set for Download or QSAR
Report error Found 39 Enz. Inhib. hit(s) with Target = 'Chromatin remodeling regulator CECR2 [424-538]'
TargetChromatin remodeling regulator CECR2 [424-538](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 321463BDBM321463(6-(but-3-en-1-yl)-4-(3-(difluoromethoxy)-5-(morpho...)
Affinity DataIC50: 10nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetChromatin remodeling regulator CECR2 [424-538](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 321470BDBM321470(6-but-3-enyl-4-[1-methyl-6-(morpholine-4-carbonyl)...)
Affinity DataIC50: 11nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetChromatin remodeling regulator CECR2 [424-538](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 321476BDBM321476(6-but-3-enyl-4-[4-fluoro-3-(morpholine-4-carbonyl)...)
Affinity DataIC50: 11nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetChromatin remodeling regulator CECR2 [424-538](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 321462BDBM321462(6-but-3-enyl-4-[4-fluoro-3-(morpholine-4-carbonyl)...)
Affinity DataIC50: 11nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetChromatin remodeling regulator CECR2 [424-538](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 321465BDBM321465(US10183009, Example 57 | 6-but-3-enyl-4-[3-methyl-...)
Affinity DataIC50: 11nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetChromatin remodeling regulator CECR2 [424-538](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 321465BDBM321465(US10183009, Example 57 | 6-but-3-enyl-4-[3-methyl-...)
Affinity DataIC50: 11nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetChromatin remodeling regulator CECR2 [424-538](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 321474BDBM321474(6-but-3-enyl-4-[4-chloro-3-(morpholine-4-carbonyl)...)
Affinity DataIC50: 12nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetChromatin remodeling regulator CECR2 [424-538](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 321468BDBM321468(6-but-3-enyl-4-[6-(morpholine-4-carbonyl)-1H-benzi...)
Affinity DataIC50: 12nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetChromatin remodeling regulator CECR2 [424-538](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 321475BDBM321475(6-but-3-enyl-4-[3-fluoro-5-(morpholine-4-carbonyl)...)
Affinity DataIC50: 14nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetChromatin remodeling regulator CECR2 [424-538](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 321467BDBM321467(6-but-3-enyl-4-[3-ethyl-7-(morpholine-4-carbonyl)b...)
Affinity DataIC50: 14nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetChromatin remodeling regulator CECR2 [424-538](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 321458BDBM321458(6-but-3-enyl-4-[3,4-difluoro-5-(morpholine-4-carbo...)
Affinity DataIC50: 17nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetChromatin remodeling regulator CECR2 [424-538](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 321459BDBM321459(6-but-3-enyl-4-[3-fluoro-5-(3-methylmorpholine-4-c...)
Affinity DataIC50: 19nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetChromatin remodeling regulator CECR2 [424-538](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 321469BDBM321469(4-(6-(but-3-en-1-yl)-7-oxo-6,7-dihydro-1H-pyrrolo[...)
Affinity DataIC50: 20nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetChromatin remodeling regulator CECR2 [424-538](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 321461BDBM321461(6-but-3-enyl-4-[3-fluoro-5-(morpholine-4-carbonyl)...)
Affinity DataIC50: 20nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetChromatin remodeling regulator CECR2 [424-538](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 321460BDBM321460(3-(6-but-3-enyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-y...)
Affinity DataIC50: 21nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetChromatin remodeling regulator CECR2 [424-538](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 321464BDBM321464(6-but-3-enyl-4-[7-(morpholine-4-carbonyl)-3H-benzi...)
Affinity DataIC50: 21nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetChromatin remodeling regulator CECR2 [424-538](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 310905BDBM310905(US10150767, Example 16 | 2-methyl-7-(6-methyl-7-ox...)
Affinity DataIC50: 36nMAssay Description:His/Flag epitope tagged CECR2424-538 was cloned, expressed, and purified to homogeneity. CECR2 binding and inhibition was assessed by monitoring the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetChromatin remodeling regulator CECR2 [424-538](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 310911BDBM310911(US10150767, Example 44 | 6-methyl-4-(2-methyl-3,4-...)
Affinity DataIC50: 54nMAssay Description:His/Flag epitope tagged CECR2424-538 was cloned, expressed, and purified to homogeneity. CECR2 binding and inhibition was assessed by monitoring the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetChromatin remodeling regulator CECR2 [424-538](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 310910BDBM310910(US10150767, Example 35 | 4-(6-methyl-7-oxo-1H-pyrr...)
Affinity DataIC50: 75nMAssay Description:His/Flag epitope tagged CECR2424-538 was cloned, expressed, and purified to homogeneity. CECR2 binding and inhibition was assessed by monitoring the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetChromatin remodeling regulator CECR2 [424-538](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 321452BDBM321452(6-but-3-enyl-4-[3-(5-methyl-1,3,4-oxadiazol-2-yl)p...)
Affinity DataIC50: 95nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetChromatin remodeling regulator CECR2 [424-538](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 321448BDBM321448(3-(6-but-3-enyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-y...)
Affinity DataIC50: 110nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetChromatin remodeling regulator CECR2 [424-538](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 310909BDBM310909(US10150767, Example 28 | 4-[4-(3,3-difluoroazetidi...)
Affinity DataIC50: 130nMAssay Description:His/Flag epitope tagged CECR2424-538 was cloned, expressed, and purified to homogeneity. CECR2 binding and inhibition was assessed by monitoring the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetChromatin remodeling regulator CECR2 [424-538](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 310912BDBM310912(US10150767, Example 47 | 3-(2,6-dimethyl-7-oxo-1H-...)
Affinity DataIC50: 130nMAssay Description:His/Flag epitope tagged CECR2424-538 was cloned, expressed, and purified to homogeneity. CECR2 binding and inhibition was assessed by monitoring the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetChromatin remodeling regulator CECR2 [424-538](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 310904BDBM310904(US10150767, Example 7 | 3-methoxy-N-[4-(6-methyl-7...)
Affinity DataIC50: 170nMAssay Description:His/Flag epitope tagged CECR2424-538 was cloned, expressed, and purified to homogeneity. CECR2 binding and inhibition was assessed by monitoring the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetChromatin remodeling regulator CECR2 [424-538](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 310908BDBM310908(US10150767, Example 26 | 6-methyl-4-(4-(4-methyl-3...)
Affinity DataIC50: 240nMAssay Description:His/Flag epitope tagged CECR2424-538 was cloned, expressed, and purified to homogeneity. CECR2 binding and inhibition was assessed by monitoring the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetChromatin remodeling regulator CECR2 [424-538](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 321473BDBM321473(3-(6-(2-cyclopropylethyl)-2-methyl-7-oxo-6,7-dihyd...)
Affinity DataIC50: 480nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetChromatin remodeling regulator CECR2 [424-538](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 321453BDBM321453(3-(6-but-2-enyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-y...)
Affinity DataIC50: 640nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetChromatin remodeling regulator CECR2 [424-538](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 310906BDBM310906(US10150767, Example 18 | N,N-dimethyl-4-(6-methyl-...)
Affinity DataIC50: 730nMAssay Description:His/Flag epitope tagged CECR2424-538 was cloned, expressed, and purified to homogeneity. CECR2 binding and inhibition was assessed by monitoring the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetChromatin remodeling regulator CECR2 [424-538](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 321472BDBM321472(4-[5-(6-acetyl-2,6-diazaspiro[3.3]heptane-2-carbon...)
Affinity DataIC50: 900nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetChromatin remodeling regulator CECR2 [424-538](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 310907BDBM310907(US10150767, Example 20 | 3-(6-ethyl-7-oxo-1H-pyrro...)
Affinity DataIC50: 1.30E+3nMAssay Description:His/Flag epitope tagged CECR2424-538 was cloned, expressed, and purified to homogeneity. CECR2 binding and inhibition was assessed by monitoring the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetChromatin remodeling regulator CECR2 [424-538](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 321456BDBM321456(4-[6-[(E)-but-2-enyl]-7-oxo-1H-pyrrolo[2,3-c]pyrid...)
Affinity DataIC50: 1.60E+3nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetChromatin remodeling regulator CECR2 [424-538](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 321471BDBM321471(4-[5-(azetidine-1-carbonyl)-2-methoxy-phenyl]-6-[(...)
Affinity DataIC50: 1.80E+3nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetChromatin remodeling regulator CECR2 [424-538](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 321455BDBM321455(4-[6-[(E)-but-2-enyl]-7-oxo-1H-pyrrolo[2,3-c]pyrid...)
Affinity DataIC50: 2.00E+3nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetChromatin remodeling regulator CECR2 [424-538](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 321449BDBM321449(3-[6-(2-methoxyethyl)-7-oxo-1H-pyrrolo[2,3-c]pyrid...)
Affinity DataIC50: 2.00E+3nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetChromatin remodeling regulator CECR2 [424-538](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 321457BDBM321457(3-[6-(2-cyclopropylethyl)-7-oxo-1H-pyrrolo[2,3-c]p...)
Affinity DataIC50: 3.40E+3nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetChromatin remodeling regulator CECR2 [424-538](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 321454BDBM321454(6-but-2-enyl-4-[4-(hydroxymethyl)phenyl]-1H-pyrrol...)
Affinity DataIC50: 4.50E+3nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetChromatin remodeling regulator CECR2 [424-538](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 321447BDBM321447(N,N-dimethyl-3-[6-(3-methylbut-2-enyl)-7-oxo-1H-py...)
Affinity DataIC50: 5.20E+3nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetChromatin remodeling regulator CECR2 [424-538](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 321451BDBM321451(3-[6-(cyclopropylmethyl)-7-oxo-1H-pyrrolo[2,3-c]py...)
Affinity DataIC50: 5.60E+3nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetChromatin remodeling regulator CECR2 [424-538](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 321450BDBM321450(3-[6-(3-methoxypropyl)-7-oxo-1H-pyrrolo[2,3-c]pyri...)
Affinity DataIC50: 9.30E+3nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent