Compile Data Set for Download or QSAR
Report error Found 106 Enz. Inhib. hit(s) with Target = 'Cyclin-A2/Cyclin-dependent kinase 1'
TargetCyclin-A2/Cyclin-dependent kinase 1(Human)
Glaxosmithkline

LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataKi:  1nM ΔG°:  -50.9kJ/molepH: 7.4 T: 2°CAssay Description:In vitro CDK enzymatic assay using purified CDK mixed with cyclin A, was incubated with substrate, and test compounds in the presence of 1.4 uM ATP/ ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2007
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 1(Human)
Glaxosmithkline

LigandPNGBDBM50059889(3-methoxy-2-methyl-4-methylamino-(2S,3S,4S,6R)-29-...)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of CDK1/Cyclin A (unknown origin)-mediated phosphorylation of peptide substrate incubated for 15 mins prior to substrate addition measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 1(Human)
Glaxosmithkline

LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human CDK1/Cyclin-A using Histone H1 as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 1(Human)
Glaxosmithkline

LigandPNGBDBM50202432(CHEMBL410883)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of human CDK1/cyclinA expressed in Baculovirus infected Sf9 cells using Biotin-aminohexyl-Ala-Arg-Arg-Pro-Met-Ser-Pro-Lys-LysLys-Ala-CONH2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2018
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 1(Human)
Glaxosmithkline

LigandPNGBDBM50263013(CHEMBL4079206)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of CDK1/cyclin A (unknown origin) after 30 mins in presence of [33P]-gamma-ATP by filter binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2020
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 1(Human)
Glaxosmithkline

LigandPNGBDBM50433369(CHEMBL2377825)
Affinity DataIC50: 7.60nMAssay Description:Inhibition of CDK1/Cyclin A (unknown origin)-mediated phosphorylation of peptide substrate incubated for 15 mins prior to substrate addition measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 1(Human)
Glaxosmithkline

LigandPNGBDBM50202434(GW276655X)
Affinity DataIC50: 10nMAssay Description:Inhibition of human CDK1/cyclinA expressed in Baculovirus infected Sf9 cells using Biotin-aminohexyl-Ala-Arg-Arg-Pro-Met-Ser-Pro-Lys-LysLys-Ala-CONH2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2018
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 1(Human)
Glaxosmithkline

LigandPNGBDBM50202329(GW305178X)
Affinity DataIC50: 12nMAssay Description:Inhibition of human CDK1/cyclinA expressed in Baculovirus infected Sf9 cells using Biotin-aminohexyl-Ala-Arg-Arg-Pro-Met-Ser-Pro-Lys-LysLys-Ala-CONH2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2018
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 1(Human)
Glaxosmithkline

LigandPNGBDBM498187(US11014911, Example 15 | US11718603, Example 15)
Affinity DataKi:  16.4nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent

TargetCyclin-A2/Cyclin-dependent kinase 1(Human)
Glaxosmithkline

LigandPNGBDBM498187(US11014911, Example 15 | US11718603, Example 15)
Affinity DataKi:  16.4nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2023
Entry Details
US Patent

TargetCyclin-A2/Cyclin-dependent kinase 1(Human)
Glaxosmithkline

LigandPNGBDBM17140((15R,18R)-28-oxa-4,14,19-triazaoctacyclo[12.11.2.1...)
Affinity DataKi:  23nM ΔG°:  -43.2kJ/molepH: 7.4 T: 2°CAssay Description:In vitro CDK enzymatic assay using purified CDK mixed with cyclin A, was incubated with substrate, and test compounds in the presence of 1.4 uM ATP/ ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2007
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 1(Human)
Glaxosmithkline

LigandPNGBDBM50330290(Cyclohexyl-[4-(3-isopropyl-1H-pyrazol-4-yl)-pyrimi...)
Affinity DataKi:  24nMAssay Description:Inhibition of human recombinant full length GST-tagged CDK1/Cyclin A2 expressed in sf9 insect cells assessed as inhibition constant using Ulight-4E-B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 1(Human)
Glaxosmithkline

LigandPNGBDBM50464620(CHEMBL4284941 | US11091476, Example 15)
Affinity DataIC50: 27nMAssay Description:Inhibition of CDK1/Cyclin-A2 (unknown origin) using histone-H1 as substrate after 90 mins by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 1(Human)
Glaxosmithkline

LigandPNGBDBM50202433(CHEMBL411426)
Affinity DataIC50: 37nMAssay Description:Inhibition of human CDK1/cyclinA expressed in Baculovirus infected Sf9 cells using Biotin-aminohexyl-Ala-Arg-Arg-Pro-Met-Ser-Pro-Lys-LysLys-Ala-CONH2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2018
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 1(Human)
Glaxosmithkline

LigandPNGBDBM50202321(CHEMBL271160)
Affinity DataIC50: 41nMAssay Description:Inhibition of human CDK1/cyclinA expressed in Baculovirus infected Sf9 cells using Biotin-aminohexyl-Ala-Arg-Arg-Pro-Met-Ser-Pro-Lys-LysLys-Ala-CONH2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2018
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 1(Human)
Glaxosmithkline

LigandPNGBDBM50202378(CHEMBL407709)
Affinity DataIC50: 43nMAssay Description:Inhibition of human CDK1/cyclinA expressed in Baculovirus infected Sf9 cells using Biotin-aminohexyl-Ala-Arg-Arg-Pro-Met-Ser-Pro-Lys-LysLys-Ala-CONH2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2018
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 1(Human)
Glaxosmithkline

LigandPNGBDBM50464612(CHEMBL4279791 | US11091476, Example 23)
Affinity DataIC50: 50nMAssay Description:Inhibition of CDK1/Cyclin-A2 (unknown origin) using histone-H1 as substrate after 90 mins by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 1(Human)
Glaxosmithkline

LigandPNGBDBM50521937(CHEMBL4564687)
Affinity DataKi:  52nMAssay Description:Inhibition of human recombinant full length GST-tagged CDK1/Cyclin A2 expressed in sf9 insect cells assessed as inhibition constant using Ulight-4E-B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 1(Human)
Glaxosmithkline

LigandPNGBDBM50464610(CHEMBL4279275 | US11091476, Example 35)
Affinity DataIC50: 54nMAssay Description:Inhibition of CDK1/Cyclin-A2 (unknown origin) using histone-H1 as substrate after 90 mins by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 1(Human)
Glaxosmithkline

LigandPNGBDBM50110183(Abemaciclib | LY-2835219 | US10696678, Example LY2...)
Affinity DataIC50: 56nMAssay Description:In vitro inhibition of CDK (CDK1, CDK4, CDK6) activity by compounds of the present invention was tested by the following method.1. Preparation of kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetCyclin-A2/Cyclin-dependent kinase 1(Human)
Glaxosmithkline

LigandPNGBDBM50521935(CHEMBL4589135)
Affinity DataKi:  63nMAssay Description:Inhibition of human recombinant full length GST-tagged CDK1/Cyclin A2 expressed in sf9 insect cells assessed as inhibition constant using Ulight-4E-B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 1(Human)
Glaxosmithkline

LigandPNGBDBM448933(N-(5-(4-Aminopiperidine-1-yl)pyridin-2-yl)-5-fluor...)
Affinity DataIC50: 64nMAssay Description:In vitro inhibition of CDK (CDK1, CDK4, CDK6) activity by compounds of the present invention was tested by the following method.1. Preparation of kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetCyclin-A2/Cyclin-dependent kinase 1(Human)
Glaxosmithkline

LigandPNGBDBM50464608(CHEMBL4278904 | US11091476, Example 19)
Affinity DataIC50: 65nMAssay Description:Inhibition of CDK1/Cyclin-A2 (unknown origin) using histone-H1 as substrate after 90 mins by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 1(Human)
Glaxosmithkline

LigandPNGBDBM50521934(CHEMBL4546255)
Affinity DataKi:  70nMAssay Description:Inhibition of human recombinant full length GST-tagged CDK1/Cyclin A2 expressed in sf9 insect cells assessed as inhibition constant using Ulight-4E-B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 1(Human)
Glaxosmithkline

LigandPNGBDBM50521936(CHEMBL4560219)
Affinity DataKi:  77nMAssay Description:Inhibition of human recombinant full length GST-tagged CDK1/Cyclin A2 expressed in sf9 insect cells assessed as inhibition constant using Ulight-4E-B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 1(Human)
Glaxosmithkline

LigandPNGBDBM50521933(CHEMBL4440980)
Affinity DataKi:  78nMAssay Description:Inhibition of human recombinant full length GST-tagged CDK1/Cyclin A2 expressed in sf9 insect cells assessed as inhibition constant using Ulight-4E-B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 1(Human)
Glaxosmithkline

LigandPNGBDBM50464631(CHEMBL4288327 | US11091476, Example 29)
Affinity DataIC50: 82nMAssay Description:Inhibition of CDK1/Cyclin-A2 (unknown origin) using histone-H1 as substrate after 90 mins by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 1(Human)
Glaxosmithkline

LigandPNGBDBM50464622(CHEMBL4280423 | US11091476, Example 7)
Affinity DataIC50: 84nMAssay Description:Inhibition of CDK1/Cyclin-A2 (unknown origin) using histone-H1 as substrate after 90 mins by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 1(Human)
Glaxosmithkline

LigandPNGBDBM448924(5-Fluoro-4-(5-fluoro-1,1-dimethyl-2,3-dihydro-1H-b...)
Affinity DataIC50: 86.6nMAssay Description:In vitro inhibition of CDK (CDK1, CDK4, CDK6) activity by compounds of the present invention was tested by the following method.1. Preparation of kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetCyclin-A2/Cyclin-dependent kinase 1(Human)
Glaxosmithkline

LigandPNGBDBM448979(N-(5-(3,5-Dimethylpiperazin-1-yl)pyridin-2-yl)-5-f...)
Affinity DataIC50: 94.8nMAssay Description:In vitro inhibition of CDK (CDK1, CDK4, CDK6) activity by compounds of the present invention was tested by the following method.1. Preparation of kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetCyclin-A2/Cyclin-dependent kinase 1(Human)
Glaxosmithkline

LigandPNGBDBM17054((5S,6R,7R,9R,16R)-16-hydroxy-6-methoxy-5-methyl-7-...)
Affinity DataKi:  95nM ΔG°:  -39.7kJ/molepH: 7.4 T: 2°CAssay Description:In vitro CDK enzymatic assay using purified CDK mixed with cyclin A, was incubated with substrate, and test compounds in the presence of 1.4 uM ATP/ ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2007
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 1(Human)
Glaxosmithkline

LigandPNGBDBM50464619(CHEMBL4292139 | US11091476, Example 16)
Affinity DataIC50: 96nMAssay Description:Inhibition of CDK1/Cyclin-A2 (unknown origin) using histone-H1 as substrate after 90 mins by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 1(Human)
Glaxosmithkline

LigandPNGBDBM50464607(CHEMBL4293340 | US11091476, Example 36)
Affinity DataIC50: 101nMAssay Description:Inhibition of CDK1/Cyclin-A2 (unknown origin) using histone-H1 as substrate after 90 mins by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 1(Human)
Glaxosmithkline

LigandPNGBDBM448930(4-(1,1-Dimethyl-2,3-dihydro-1H-benzo[d]pyrrolo[1,2...)
Affinity DataIC50: 109nMAssay Description:In vitro inhibition of CDK (CDK1, CDK4, CDK6) activity by compounds of the present invention was tested by the following method.1. Preparation of kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetCyclin-A2/Cyclin-dependent kinase 1(Human)
Glaxosmithkline

LigandPNGBDBM50521938(CHEMBL4545456)
Affinity DataKi:  110nMAssay Description:Inhibition of human recombinant full length GST-tagged CDK1/Cyclin A2 expressed in sf9 insect cells assessed as inhibition constant using Ulight-4E-B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 1(Human)
Glaxosmithkline

LigandPNGBDBM498185(US11014911, Example 13 | US11718603, Example 13 | ...)
Affinity DataKi:  110nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2023
Entry Details
US Patent

TargetCyclin-A2/Cyclin-dependent kinase 1(Human)
Glaxosmithkline

LigandPNGBDBM50521925(CHEMBL4529532)
Affinity DataKi:  110nMAssay Description:Inhibition of human recombinant full length GST-tagged CDK1/Cyclin A2 expressed in sf9 insect cells assessed as inhibition constant using Ulight-4E-B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 1(Human)
Glaxosmithkline

LigandPNGBDBM50464603(CHEMBL4291541 | US11091476, Example 11)
Affinity DataIC50: 110nMAssay Description:Inhibition of CDK1/Cyclin-A2 (unknown origin) using histone-H1 as substrate after 90 mins by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 1(Human)
Glaxosmithkline

LigandPNGBDBM498185(US11014911, Example 13 | US11718603, Example 13 | ...)
Affinity DataKi:  110nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
US Patent

TargetCyclin-A2/Cyclin-dependent kinase 1(Human)
Glaxosmithkline

LigandPNGBDBM50464617(CHEMBL4284737 | US11091476, Example 34)
Affinity DataIC50: 112nMAssay Description:Inhibition of CDK1/Cyclin-A2 (unknown origin) using histone-H1 as substrate after 90 mins by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 1(Human)
Glaxosmithkline

LigandPNGBDBM50464605(CHEMBL4289967)
Affinity DataIC50: 125nMAssay Description:Inhibition of CDK1/Cyclin-A2 (unknown origin) using histone-H1 as substrate after 90 mins by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 1(Human)
Glaxosmithkline

LigandPNGBDBM50464628(CHEMBL4284301 | US11091476, Example 24)
Affinity DataIC50: 131nMAssay Description:Inhibition of CDK1/Cyclin-A2 (unknown origin) using histone-H1 as substrate after 90 mins by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 1(Human)
Glaxosmithkline

LigandPNGBDBM50464629(CHEMBL4286823 | US11091476, Example 21)
Affinity DataIC50: 135nMAssay Description:Inhibition of CDK1/Cyclin-A2 (unknown origin) using histone-H1 as substrate after 90 mins by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 1(Human)
Glaxosmithkline

LigandPNGBDBM50464626(CHEMBL4288134 | US11091476, Example 32)
Affinity DataIC50: 142nMAssay Description:Inhibition of CDK1/Cyclin-A2 (unknown origin) using histone-H1 as substrate after 90 mins by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 1(Human)
Glaxosmithkline

LigandPNGBDBM50464614(CHEMBL4277525 | US11091476, Example 6)
Affinity DataIC50: 152nMAssay Description:Inhibition of CDK1/Cyclin-A2 (unknown origin) using histone-H1 as substrate after 90 mins by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 1(Human)
Glaxosmithkline

LigandPNGBDBM50464630(CHEMBL4281514 | US11091476, Example 18)
Affinity DataIC50: 153nMAssay Description:Inhibition of CDK1/Cyclin-A2 (unknown origin) using histone-H1 as substrate after 90 mins by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 1(Human)
Glaxosmithkline

LigandPNGBDBM50464638(CHEMBL4292616 | US11091476, Example 33)
Affinity DataIC50: 166nMAssay Description:Inhibition of CDK1/Cyclin-A2 (unknown origin) using histone-H1 as substrate after 90 mins by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 1(Human)
Glaxosmithkline

LigandPNGBDBM50202312(CHEMBL272387)
Affinity DataIC50: 170nMAssay Description:Inhibition of human CDK1/cyclinA expressed in Baculovirus infected Sf9 cells using Biotin-aminohexyl-Ala-Arg-Arg-Pro-Met-Ser-Pro-Lys-LysLys-Ala-CONH2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2018
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 1(Human)
Glaxosmithkline

LigandPNGBDBM50464632(CHEMBL4279832 | US11091476, Example 30)
Affinity DataIC50: 176nMAssay Description:Inhibition of CDK1/Cyclin-A2 (unknown origin) using histone-H1 as substrate after 90 mins by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 1(Human)
Glaxosmithkline

LigandPNGBDBM50521940(CHEMBL4539133)
Affinity DataKi:  210nMAssay Description:Inhibition of human recombinant full length GST-tagged CDK1/Cyclin A2 expressed in sf9 insect cells assessed as inhibition constant using Ulight-4E-B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
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