Compile Data Set for Download or QSAR
Report error Found 5409 Enz. Inhib. hit(s) with Target = 'Cyclin-dependent kinase 1'
TargetCyclin-dependent kinase 14(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM710562(US12187701, Compound FMF-03-200-1)
Affinity DataIC50: 0.100nMAssay Description:Lanthascreen Eu kinase binding assays were conducted for Cdk14/CycY largely as performed in the commercial assay service by Life Technologies, but in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/22/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 14(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM710562(US12187701, Compound FMF-03-200-1)
Affinity DataIC50: 0.100nMAssay Description:Lanthascreen Eu kinase binding assays were conducted for Cdk14/CycY largely as performed in the commercial assay service by Life Technologies, but in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/22/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 14(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM710563(US12187701, Compound FMF-03-200-2)
Affinity DataIC50: 0.100nMAssay Description:Lanthascreen Eu kinase binding assays were conducted for Cdk14/CycY largely as performed in the commercial assay service by Life Technologies, but in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/22/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 1(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50164702(4-[4-(3H-Benzoimidazol-5-ylamino)-5-trifluoromethy...)
Affinity DataIC50: 0.100nMAssay Description:Inhibitory concentration against Cyclin dependent kinase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM84533(BDBM50375663 | Alsterpaullone derivative, 7)
Affinity DataIC50: 0.230nMpH: 7.5 T: 2°CAssay Description:Kinase activity assay using GSK-3beta, CDK1/cyclin B and CDK5/p25.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1/G1/S-specific cyclin-D3(Human)
Gan & Lee Pharmaceuticals

US Patent
LigandPNGBDBM50464609(CHEMBL4289226 | US11091476, Example 20)
Affinity DataIC50: 0.240nMAssay Description: 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/μl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 1(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50594620(CHEMBL5176826)
Affinity DataKi:  0.350nMAssay Description:Inhibition of CDK1 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 14(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM710623(US12187701, Compound FMF-04-184-1)
Affinity DataIC50: 0.400nMAssay Description:Lanthascreen Eu kinase binding assays were conducted for Cdk14/CycY largely as performed in the commercial assay service by Life Technologies, but in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/22/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 1/G1/S-specific cyclin-D3(Human)
Gan & Lee Pharmaceuticals

US Patent
LigandPNGBDBM50464614(CHEMBL4277525 | US11091476, Example 6)
Affinity DataIC50: 0.420nMAssay Description: 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/μl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 1/G1/S-specific cyclin-D3(Human)
Gan & Lee Pharmaceuticals

US Patent
LigandPNGBDBM50464614(CHEMBL4277525 | US11091476, Example 6)
Affinity DataIC50: 0.420nMAssay Description: 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/μl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 1/G1/S-specific cyclin-D3(Human)
Gan & Lee Pharmaceuticals

US Patent
LigandPNGBDBM50464614(CHEMBL4277525 | US11091476, Example 6)
Affinity DataIC50: 0.420nMAssay Description: 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/μl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 1/G1/S-specific cyclin-D3(Human)
Gan & Lee Pharmaceuticals

US Patent
LigandPNGBDBM50464632(CHEMBL4279832 | US11091476, Example 30)
Affinity DataIC50: 0.430nMAssay Description: 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/μl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 1/G1/S-specific cyclin-D3(Human)
Gan & Lee Pharmaceuticals

US Patent
LigandPNGBDBM50464636(CHEMBL4287693 | US11091476, Example 22)
Affinity DataIC50: 0.5nMAssay Description: 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/μl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 16(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM12621(2,4-Diamino-5-ketopyrimidine 39 | 5-[(2,3-difluoro...)
Affinity DataKd:  0.540nMAssay Description:Binding constant for PCTK1 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50613673(CHEMBL1964259)
Affinity DataIC50: 0.540nMAssay Description:Inhibition of human CDK1 using Biotinaminohexyl-Ala-Arg-Arg-Pro-Met-Ser-Pro-Lys-LysLys-Ala-CONH2 peptide as substrate incubated for 20 to 30 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
LigandPNGBDBM50191929(2-(4-(4-(1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of CDK1/cyclinB by Flashplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50191913(N-(2-methyl-4-(2-(pyrrolidin-1-yl)ethyl)phenyl)-4-...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of CDK1/cyclinB by Flashplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50214095(CHEMBL248713 | CHEMBL511394 | N-((5-(3-(5-fluoro-1...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50214095(CHEMBL248713 | CHEMBL511394 | N-((5-(3-(5-fluoro-1...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of CDK1/cyclinBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 14(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM710629(US12187701, Compound FMF-05-033-1)
Affinity DataIC50: 0.800nMAssay Description:Lanthascreen Eu kinase binding assays were conducted for Cdk14/CycY largely as performed in the commercial assay service by Life Technologies, but in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/22/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 1(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50297122((R)-10-Methyl-9,10,11,12-tetrahydro-7-thia-4,9,12-...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50214115(N-((5-(3-(5-methoxy-1H-benzo[d]imidazol-2-yl)-1H-p...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 14(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM710564(US12187701, Compound FMF-04-172-2)
Affinity DataIC50: 0.800nMAssay Description:Lanthascreen Eu kinase binding assays were conducted for Cdk14/CycY largely as performed in the commercial assay service by Life Technologies, but in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/22/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 17(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM12621(2,4-Diamino-5-ketopyrimidine 39 | 5-[(2,3-difluoro...)
Affinity DataKd:  0.860nMAssay Description:Binding constant for PCTK2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 13(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM478951(2-(6-(1-acryloyl-2,5-dihydro-1H-pyrrol-3-yl)pyridi...)
Affinity DataIC50: 0.900nMAssay Description:LanthaScreen Eu Kinase Binding Assays are based on the binding and displacement of Alexa Fluor 647-labeled, ATP-competitive kinase inhibitor scaffold...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetCyclin-dependent kinase 16(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM710570(US12187701, Compound FMF-03-198-2)
Affinity DataIC50: 0.900nMAssay Description:Lanthascreen Eu kinase binding assays were conducted for Cdk14/CycY largely as performed in the commercial assay service by Life Technologies, but in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/22/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 14(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM710569(US12187701, Compound FMF-03-198-1)
Affinity DataIC50: 0.900nMAssay Description:Lanthascreen Eu kinase binding assays were conducted for Cdk14/CycY largely as performed in the commercial assay service by Life Technologies, but in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/22/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 16(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM710570(US12187701, Compound FMF-03-198-2)
Affinity DataIC50: 0.900nMAssay Description:Lanthascreen Eu kinase binding assays were conducted for Cdk14/CycY largely as performed in the commercial assay service by Life Technologies, but in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/22/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 14(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM710569(US12187701, Compound FMF-03-198-1)
Affinity DataIC50: 0.900nMAssay Description:Lanthascreen Eu kinase binding assays were conducted for Cdk14/CycY largely as performed in the commercial assay service by Life Technologies, but in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/22/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 14(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM710569(US12187701, Compound FMF-03-198-1)
Affinity DataIC50: 0.900nMAssay Description:Lanthascreen Eu kinase binding assays were conducted for Cdk14/CycY largely as performed in the commercial assay service by Life Technologies, but in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/22/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 1(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50164693(N*2*-(3H-Benzoimidazol-5-yl)-N*4*-(2-chloro-phenyl...)
Affinity DataIC50: 0.900nMAssay Description:Inhibitory concentration against Cyclin dependent kinase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 16(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM710570(US12187701, Compound FMF-03-198-2)
Affinity DataIC50: 0.900nMAssay Description:Lanthascreen Eu kinase binding assays were conducted for Cdk14/CycY largely as performed in the commercial assay service by Life Technologies, but in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/22/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 13(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM31085(cid_11409972 | 1-[4-[(4-ethylpiperazin-1-yl)methyl...)
Affinity DataKd:  0.940nMAssay Description:Binding constant for CDC2L5 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 17(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM24654(pyrazole diamide, 33 | 4-N-(2,6-dichlorobenzene)-3...)
Affinity DataKd:  0.950nMAssay Description:Binding constant for PCTK2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1/G1/S-specific cyclin-D3(Human)
Gan & Lee Pharmaceuticals

US Patent
LigandPNGBDBM50464623(CHEMBL4287743 | US11091476, Example 28)
Affinity DataIC50: 0.960nMAssay Description: 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/μl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 1(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50192071((13R,15S)-13-methyl-16-oxa-8,9,12,22,24-pentaazahe...)
Affinity DataIC50: 1nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139171(Dinaciclib | MK-7965 | SCH-727965 | US11643396, Ex...)
Affinity DataIC50: 1nMAssay Description:Inhibition of CDK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
LigandPNGBDBM50191918(N-(2-methyl-4-(2-(piperidin-1-yl)ethyl)phenyl)-4-(...)
Affinity DataIC50: 1nMAssay Description:Inhibition of CDK1/cyclinB by Flashplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50297120((R)-9-Methyl-8,9,10,11-tetrahydro-3-oxa-6-thia-8,1...)
Affinity DataIC50: 1nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50400801(CHEMBL215803)
Affinity DataIC50: 1nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50400801(CHEMBL215803)
Affinity DataIC50: 1nMAssay Description:Inhibition of CDK6More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCyclin-dependent kinase 12(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50642414(CHEMBL5573550)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human CDK12/Cyclin K using RNA Pol II-CTD as substrate preincubated for ~20 mins followed by 33P-ATP addition measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 1(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50400801(CHEMBL215803)
Affinity DataIC50: 1nMAssay Description:Inhibition of CDK4More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50164693(N*2*-(3H-Benzoimidazol-5-yl)-N*4*-(2-chloro-phenyl...)
Affinity DataIC50: 1nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetCyclin-dependent kinase 12(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50642423(CHEMBL5567321)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human CDK12/Cyclin K using RNA Pol II-CTD as substrate preincubated for ~20 mins followed by 33P-ATP addition measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 1(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139171(Dinaciclib | MK-7965 | SCH-727965 | US11643396, Ex...)
Affinity DataIC50: 1nMAssay Description:Inhibition of CDK1 (unknown origin) expressed in Sf9 insect cells using biotinylated peptide derived Histone H1 as substrate incubated for 1 hr in pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 12(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50652792(CHEMBL3752910)
Affinity DataKd:  1nMAssay Description:Binding affinity to human CDK12 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 1/G1/S-specific cyclin-D3(Human)
Gan & Lee Pharmaceuticals

US Patent
LigandPNGBDBM50464630(CHEMBL4281514 | US11091476, Example 18)
Affinity DataIC50: 1nMAssay Description: 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/μl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 14(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM710563(US12187701, Compound FMF-03-200-2)
Affinity DataIC50: 1nMAssay Description:Lanthascreen Eu kinase binding assays were conducted for Cdk14/CycY largely as performed in the commercial assay service by Life Technologies, but in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/22/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 1/G1/S-specific cyclin-D3(Human)
Gan & Lee Pharmaceuticals

US Patent
LigandPNGBDBM50464618(CHEMBL4294940 | US11091476, Example 25)
Affinity DataIC50: 1.09nMAssay Description: 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/μl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

Displayed 1 to 50 (of 5409 total ) | Next | Last >>
Jump to: