Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with Target = 'Dihydropyrimidine dehydrogenase [NADP(+)]'
TargetDihydropyrimidine dehydrogenase [NADP(+)](Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50124202(5-Ethynyl-1H-pyrimidine-2,4-dione | CHEMBL355200)
Affinity DataIC50: 14nMAssay Description:Inhibitory activity against dihydropyrimidine dehydrogenase (DPD)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDihydropyrimidine dehydrogenase [NADP(+)](Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50124200(5-((E)-Styryl)-1H-pyrimidine-2,4-dione | CHEMBL352...)
Affinity DataIC50: 43nMAssay Description:Inhibitory activity against dihydropyrimidine dehydrogenase (DPD)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydropyrimidine dehydrogenase [NADP(+)](Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50124204(5-Vinyl-1H-pyrimidine-2,4-dione | CHEMBL170188)
Affinity DataIC50: 89nMAssay Description:Inhibitory activity against dihydropyrimidine dehydrogenase (DPD)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydropyrimidine dehydrogenase [NADP(+)](Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50124201(5-(3-Benzyloxy-benzyl)-1H-pyrimidine-2,4-dione | C...)
Affinity DataIC50: 97nMAssay Description:Inhibitory activity against dihydropyrimidine dehydrogenase (DPD)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydropyrimidine dehydrogenase [NADP(+)](Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50124205(2,4-Dioxo-1,2,3,4-tetrahydro-pyrimidine-5-carbonit...)
Affinity DataIC50: 200nMAssay Description:Inhibitory activity against dihydropyrimidine dehydrogenase (DPD)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydropyrimidine dehydrogenase [NADP(+)](Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50124203(5-Iodo-1H-pyrimidine-2,4-dione | 5-IODOURACIL | CH...)
Affinity DataIC50: 220nMAssay Description:Inhibitory activity against dihydropyrimidine dehydrogenase (DPD)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)