Compile Data Set for Download or QSAR
Report error Found 182 Enz. Inhib. hit(s) with Target = 'Dual specificity mitogen-activated protein kinase kinase 7'
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Sabila Biosciences

US Patent
LigandPNGBDBM473175(US10844038, Example 46 A. | (3S,4S)-3-((4-amino-3-...)
Affinity DataKd:  5.50E+3nMAssay Description:Kd: For most assays, kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phase an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
US Patent

TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Sabila Biosciences

US Patent
LigandPNGBDBM473172(US10844038, Example 46 B. | (3R,4R)-3-((4-amino-3-...)
Affinity DataKd:  5.50E+3nMAssay Description:Kd: For most assays, kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phase an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
US Patent

TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Sabila Biosciences

US Patent
LigandPNGBDBM50504346(CHEBI:64215 | CHEMBL402468)
Affinity DataKd:  2.70E+4nMAssay Description:Binding affinity to MKK7 (unknown origin) expressed in HEK293 cells assessed as dissociation constant by kinomescan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Sabila Biosciences

US Patent
LigandPNGBDBM50504348(CHEMBL189010)
Affinity DataKd:  1.40E+3nMAssay Description:Binding affinity to MKK7 (unknown origin) expressed in HEK293 cells assessed as dissociation constant by kinomescan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Sabila Biosciences

US Patent
LigandPNGBDBM50012070(CHEMBL295316 | plumbagin | 5-hydroxy-2-methylnapht...)
Affinity DataKd:  1.40E+4nMAssay Description:Binding affinity to MKK7 (unknown origin) expressed in HEK293 cells assessed as dissociation constant by kinomescan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Sabila Biosciences

US Patent
LigandPNGBDBM50504351(CHEMBL100206)
Affinity DataKd:  230nMAssay Description:Binding affinity to MKK7 (unknown origin) expressed in HEK293 cells assessed as dissociation constant by kinomescan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Sabila Biosciences

US Patent
LigandPNGBDBM50264040(3-[(3-Methyl-1,4-dioxo-1,4-dihydronaphthalen-2-yl)...)
Affinity DataKd:  1.50E+4nMAssay Description:Binding affinity to MKK7 (unknown origin) expressed in HEK293 cells assessed as dissociation constant by kinomescan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Sabila Biosciences

US Patent
LigandPNGBDBM50504352(CHEMBL4450909)
Affinity DataKd:  1.30E+4nMAssay Description:Binding affinity to MKK7 (unknown origin) expressed in HEK293 cells assessed as dissociation constant by kinomescan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Sabila Biosciences

US Patent
LigandPNGBDBM50504353(CHEMBL4450216)
Affinity DataKd:  1.40E+4nMAssay Description:Binding affinity to MKK7 (unknown origin) expressed in HEK293 cells assessed as dissociation constant by kinomescan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Sabila Biosciences

US Patent
LigandPNGBDBM50543(SMR000312850 | 3-[[3-chloranyl-1,4-bis(oxidanylide...)
Affinity DataKd:  1.90E+3nMAssay Description:Binding affinity to MKK7 (unknown origin) expressed in HEK293 cells assessed as dissociation constant by kinomescan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Sabila Biosciences

US Patent
LigandPNGBDBM50504347(CHEMBL365781)
Affinity DataKd:  2.10E+3nMAssay Description:Binding affinity to MKK7 (unknown origin) expressed in HEK293 cells assessed as dissociation constant by kinomescan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Sabila Biosciences

US Patent
LigandPNGBDBM50504360(CHEMBL4559690)
Affinity DataKd:  1.30E+4nMAssay Description:Binding affinity to MKK7 (unknown origin) expressed in HEK293 cells assessed as dissociation constant by kinomescan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Sabila Biosciences

US Patent
LigandPNGBDBM50208827(NSC-95397 | cid_262093 | N1786 (NSC95397) | CHEMBL...)
Affinity DataKd:  1.10E+3nMAssay Description:Binding affinity to MKK7 (unknown origin) expressed in HEK293 cells assessed as dissociation constant by kinomescan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Sabila Biosciences

US Patent
LigandPNGBDBM50504361(CHEMBL4452484)
Affinity DataKd:  4.60E+3nMAssay Description:Binding affinity to MKK7 (unknown origin) expressed in HEK293 cells assessed as dissociation constant by kinomescan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Sabila Biosciences

US Patent
LigandPNGBDBM50505541(CHEMBL4465866)
Affinity DataKd:  293nMAssay Description:Binding affinity to recombinant human full-length N-terminal GST-tagged MAP2K7 (1 to 419 residues) expressed in baculovirus expression system using J...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Sabila Biosciences

US Patent
LigandPNGBDBM50567686(CHEMBL4798975)
Affinity DataKd:  5.00E+3nMAssay Description:Binding affinity to wild-type human full length MKK7 (M1 to R419 residues) expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Sabila Biosciences

US Patent
LigandPNGBDBM50567687(CHEMBL4865410)
Affinity DataKd:  5.00E+3nMAssay Description:Binding affinity to wild-type human full length MKK7 (M1 to R419 residues) expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Sabila Biosciences

US Patent
LigandPNGBDBM50258966(CHEMBL4071151)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of N-terminal 6XHis-tagged recombinant MKK7 (117 to 423 residues) in human U2OS assessed as reduction in c-Jun phosphorylation level incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Sabila Biosciences

US Patent
LigandPNGBDBM50594447(CHEMBL5178181)
Affinity DataEC50: >900nMAssay Description:Inhibition of N-terminal 6XHis-tagged recombinant MKK7 (117 to 423 residues) in human U2OS assessed as reduction in c-Jun phosphorylation level incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Sabila Biosciences

US Patent
LigandPNGBDBM50594444(CHEMBL5174214)
Affinity DataEC50:  380nMAssay Description:Inhibition of N-terminal 6XHis-tagged recombinant MKK7 (117 to 423 residues) in human U2OS assessed as reduction in c-Jun phosphorylation level incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Sabila Biosciences

US Patent
LigandPNGBDBM50594448(CHEMBL5203494)
Affinity DataEC50:  1.09E+3nMAssay Description:Inhibition of N-terminal 6XHis-tagged recombinant MKK7 (117 to 423 residues) in human U2OS assessed as reduction in c-Jun phosphorylation level incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Sabila Biosciences

US Patent
LigandPNGBDBM50594449(CHEMBL5200766)
Affinity DataEC50: >500nMAssay Description:Inhibition of N-terminal 6XHis-tagged recombinant MKK7 (117 to 423 residues) in human U2OS assessed as reduction in c-Jun phosphorylation level incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Sabila Biosciences

US Patent
LigandPNGBDBM50594445(CHEMBL5195838)
Affinity DataEC50:  265nMAssay Description:Inhibition of N-terminal 6XHis-tagged recombinant MKK7 (117 to 423 residues) in human U2OS assessed as reduction in c-Jun phosphorylation level incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Sabila Biosciences

US Patent
LigandPNGBDBM50594446(CHEMBL5169325)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of N-terminal 6XHis-tagged recombinant MKK7 (117 to 423 residues) in human U2OS assessed as reduction in c-Jun phosphorylation level incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Sabila Biosciences

US Patent
LigandPNGBDBM50594450(CHEMBL5184750)
Affinity DataEC50: <3.00E+3nMAssay Description:Inhibition of N-terminal 6XHis-tagged recombinant MKK7 (117 to 423 residues) in human U2OS assessed as reduction in c-Jun phosphorylation level incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Sabila Biosciences

US Patent
LigandPNGBDBM50594451(CHEMBL5181040)
Affinity DataEC50: >5.00E+3nMAssay Description:Inhibition of N-terminal 6XHis-tagged recombinant MKK7 (117 to 423 residues) in human U2OS assessed as reduction in c-Jun phosphorylation level incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Sabila Biosciences

US Patent
LigandPNGBDBM50553869(CHEMBL4764965)
Affinity DataEC50: <100nMAssay Description:Inhibition of N-terminal 6XHis-tagged recombinant MKK7 (117 to 423 residues) in human U2OS assessed as reduction in c-Jun phosphorylation level incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Sabila Biosciences

US Patent
LigandPNGBDBM50308060(CEP-701 | 16-hydroxy-16-(hydroxymethyl)-15-methyl-...)
Affinity DataKd:  80nMAssay Description:Binding constant for MKK7 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Sabila Biosciences

US Patent
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataKd:  30nMAssay Description:Binding constant for MKK7 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Sabila Biosciences

US Patent
LigandPNGBDBM50326053(PKC-412 | CHEMBL608533 | US20240132489, Compound S...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for MKK7 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Sabila Biosciences

US Patent
LigandPNGBDBM50026612(BIBF-1120 | Nintedanib | Vargatef | US10981896, Co...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for MKK7 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Sabila Biosciences

US Patent
LigandPNGBDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for MKK7 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Sabila Biosciences

US Patent
LigandPNGBDBM50331096(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-6-methoxy-7...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for MKK7 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Sabila Biosciences

US Patent
LigandPNGBDBM31095(5-[(Z)-(5-fluoranyl-2-oxidanylidene-1H-indol-3-yli...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for MKK7 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Sabila Biosciences

US Patent
LigandPNGBDBM25121(4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for MKK7 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Sabila Biosciences

US Patent
LigandPNGBDBM50128285(3-(1-Methyl-1H-indol-3-yl)-4-[1-(1-pyridin-2-ylmet...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for MKK7 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Sabila Biosciences

US Patent
LigandPNGBDBM13533(1-[5-tert-butyl-2-(p-tolyl)pyrazol-3-yl]-3-[4-(2-m...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for MKK7 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Sabila Biosciences

US Patent
LigandPNGBDBM50193995(CP-690550 | 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrro...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for MKK7 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Sabila Biosciences

US Patent
LigandPNGBDBM17055((9S)-9-[(dimethylamino)methyl]-6,7,10,11-tetrahydr...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for MKK7 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Sabila Biosciences

US Patent
LigandPNGBDBM27817(2-{[2-({1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for MKK7 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Sabila Biosciences

US Patent
LigandPNGBDBM50332294(N-tert-butyl-3-(5-methyl-2-(4-(2-(pyrrolidin-1-yl)...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for MKK7 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Sabila Biosciences

US Patent
LigandPNGBDBM16673(Xarelto | BAY439006 | CHEMBL1336 | BAY 43-9006 | 4...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for MKK7 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Sabila Biosciences

US Patent
LigandPNGBDBM482158(TAE684 | BDBM50242742)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for MKK7 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Sabila Biosciences

US Patent
LigandPNGBDBM50355501(RUXOLITINIB PHOSPHATE | INCB-018424 | RUXOLITINIB ...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for MKK7 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Sabila Biosciences

US Patent
LigandPNGBDBM15138(Biochemistry 469551 Compound 11 | 5-indazolyl pyri...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for MKK7 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Sabila Biosciences

US Patent
LigandPNGBDBM12621(2,4-Diamino-5-ketopyrimidine 39 | 5-[(2,3-difluoro...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for MKK7 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Sabila Biosciences

US Patent
LigandPNGBDBM50184807((R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-me...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for MKK7 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Sabila Biosciences

US Patent
LigandPNGBDBM50355499(CHEMBL1908395 | CHEMBL1908842 | US20250129067, Com...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for MKK7 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Sabila Biosciences

US Patent
LigandPNGBDBM25045(CHEMBL538346 | mTOR Inhibitor, PI103 | PI-103 | 3-...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for MKK7 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Sabila Biosciences

US Patent
LigandPNGBDBM13336(4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for MKK7 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
Displayed 1 to 50 (of 182 total ) | Next | Last >>
Jump to: