Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor [1-18,20-745,747-749,751-1210]'
LigandChemical structure of BindingDB Monomer ID 494877BDBM494877(US10994015, Example 11)
Affinity DataIC50: 0.140nMAssay Description:All compounds and PROTACs were serially diluted in three-fold increments using 100% DMSO, followed by an intermediate 10-fold dilution using Buffer A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 494873BDBM494873(US10994015, Example 7)
Affinity DataIC50: 1nMAssay Description:All compounds and PROTACs were serially diluted in three-fold increments using 100% DMSO, followed by an intermediate 10-fold dilution using Buffer A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 495019BDBM495019(US10994015, Example 319)
Affinity DataIC50: 1.30nMAssay Description:All compounds and PROTACs were serially diluted in three-fold increments using 100% DMSO, followed by an intermediate 10-fold dilution using Buffer A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 494874BDBM494874(US10994015, Example 8 | 4-((17-(4-(4-(4-((2-chloro...)
Affinity DataIC50: 1.70nMAssay Description:All compounds and PROTACs were serially diluted in three-fold increments using 100% DMSO, followed by an intermediate 10-fold dilution using Buffer A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 494875BDBM494875(US10994015, Example 9)
Affinity DataIC50: 1.90nMAssay Description:All compounds and PROTACs were serially diluted in three-fold increments using 100% DMSO, followed by an intermediate 10-fold dilution using Buffer A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 494867BDBM494867(US10994015, Example 1 | (2S,4R)-1-((S)-2-(tert-but...)
Affinity DataIC50: 2.10nMAssay Description:All compounds and PROTACs were serially diluted in three-fold increments using 100% DMSO, followed by an intermediate 10-fold dilution using Buffer A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 494872BDBM494872(US10994015, Example 6)
Affinity DataIC50: 2.90nMAssay Description:All compounds and PROTACs were serially diluted in three-fold increments using 100% DMSO, followed by an intermediate 10-fold dilution using Buffer A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 494868BDBM494868(US10994015, Example 2)
Affinity DataIC50: 4nMAssay Description:All compounds and PROTACs were serially diluted in three-fold increments using 100% DMSO, followed by an intermediate 10-fold dilution using Buffer A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 494871BDBM494871(US10994015, Example 5)
Affinity DataIC50: 4.10nMAssay Description:All compounds and PROTACs were serially diluted in three-fold increments using 100% DMSO, followed by an intermediate 10-fold dilution using Buffer A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 494870BDBM494870(US10994015, Example 4)
Affinity DataIC50: 4.20nMAssay Description:All compounds and PROTACs were serially diluted in three-fold increments using 100% DMSO, followed by an intermediate 10-fold dilution using Buffer A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 494869BDBM494869(US10994015, Example 3)
Affinity DataIC50: 5.5nMAssay Description:All compounds and PROTACs were serially diluted in three-fold increments using 100% DMSO, followed by an intermediate 10-fold dilution using Buffer A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 495017BDBM495017(US10994015, Example 313 | US10994015, Example 314)
Affinity DataIC50: 7.5nMAssay Description:All compounds and PROTACs were serially diluted in three-fold increments using 100% DMSO, followed by an intermediate 10-fold dilution using Buffer A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 494922BDBM494922(US10994015, Example 13)
Affinity DataIC50: 37nMAssay Description:All compounds and PROTACs were serially diluted in three-fold increments using 100% DMSO, followed by an intermediate 10-fold dilution using Buffer A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 495012BDBM495012(US10994015, Example 308)
Affinity DataIC50: 53nMAssay Description:All compounds and PROTACs were serially diluted in three-fold increments using 100% DMSO, followed by an intermediate 10-fold dilution using Buffer A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 494879BDBM494879(US10994015, Example 12)
Affinity DataIC50: 83nMAssay Description:All compounds and PROTACs were serially diluted in three-fold increments using 100% DMSO, followed by an intermediate 10-fold dilution using Buffer A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 494924BDBM494924(US10994015, Example 15)
Affinity DataIC50: 140nMAssay Description:All compounds and PROTACs were serially diluted in three-fold increments using 100% DMSO, followed by an intermediate 10-fold dilution using Buffer A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 495016BDBM495016(US10994015, Example 312)
Affinity DataIC50: 170nMAssay Description:All compounds and PROTACs were serially diluted in three-fold increments using 100% DMSO, followed by an intermediate 10-fold dilution using Buffer A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 494923BDBM494923(US10994015, Example 14 | (2S,4R)-1-((S)-2-(tert-bu...)
Affinity DataIC50: 200nMAssay Description:All compounds and PROTACs were serially diluted in three-fold increments using 100% DMSO, followed by an intermediate 10-fold dilution using Buffer A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 495010BDBM495010(US10994015, Example 306)
Affinity DataIC50: 380nMAssay Description:All compounds and PROTACs were serially diluted in three-fold increments using 100% DMSO, followed by an intermediate 10-fold dilution using Buffer A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 495005BDBM495005(US10994015, Example 301 | 2-(2,6-dioxopiperidin-3-...)
Affinity DataIC50: 1.60E+3nMAssay Description:All compounds and PROTACs were serially diluted in three-fold increments using 100% DMSO, followed by an intermediate 10-fold dilution using Buffer A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 495013BDBM495013(US10994015, Example 309)
Affinity DataIC50: 1.90E+3nMAssay Description:All compounds and PROTACs were serially diluted in three-fold increments using 100% DMSO, followed by an intermediate 10-fold dilution using Buffer A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 494876BDBM494876(US10994015, Example 10)
Affinity DataIC50: 3.70E+3nMAssay Description:All compounds and PROTACs were serially diluted in three-fold increments using 100% DMSO, followed by an intermediate 10-fold dilution using Buffer A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 495011BDBM495011(US10994015, Example 307 | 2-(7-((4-(3-(4-(4-(2-(2,...)
Affinity DataIC50: 3.80E+3nMAssay Description:All compounds and PROTACs were serially diluted in three-fold increments using 100% DMSO, followed by an intermediate 10-fold dilution using Buffer A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 495014BDBM495014(US10994015, Example 310)
Affinity DataIC50: 6.00E+3nMAssay Description:All compounds and PROTACs were serially diluted in three-fold increments using 100% DMSO, followed by an intermediate 10-fold dilution using Buffer A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 494931BDBM494931(US10994015, Example 73)
Affinity DataIC50: 8.10E+3nMAssay Description:All compounds and PROTACs were serially diluted in three-fold increments using 100% DMSO, followed by an intermediate 10-fold dilution using Buffer A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 495015BDBM495015(US10994015, Example 311)
Affinity DataIC50: 9.00E+3nMAssay Description:All compounds and PROTACs were serially diluted in three-fold increments using 100% DMSO, followed by an intermediate 10-fold dilution using Buffer A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 495017BDBM495017(US10994015, Example 313 | US10994015, Example 314)
Affinity DataIC50: 1.00E+4nMAssay Description:All compounds and PROTACs were serially diluted in three-fold increments using 100% DMSO, followed by an intermediate 10-fold dilution using Buffer A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 494928BDBM494928(US10994015, Example 70 | 2-(2,6-dioxopiperidin-3-y...)
Affinity DataIC50: 3.00E+4nMAssay Description:All compounds and PROTACs were serially diluted in three-fold increments using 100% DMSO, followed by an intermediate 10-fold dilution using Buffer A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 494929BDBM494929(US10994015, Example 71 | 2-(2,6-dioxopiperidin-3-y...)
Affinity DataIC50: 3.00E+4nMAssay Description:All compounds and PROTACs were serially diluted in three-fold increments using 100% DMSO, followed by an intermediate 10-fold dilution using Buffer A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2021
Entry Details
US Patent