Compile Data Set for Download or QSAR
Report error Found 49 Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor [695-745,751-1022,T790M,C797S]'
TargetEpidermal growth factor receptor [695-745,751-1022,T790M,C797S](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 525541BDBM525541(US11174245, # I-219)
Affinity DataIC50: 0.100nMAssay Description:5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [695-745,751-1022,T790M,C797S](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 525546BDBM525546(US11174245, # I-224)
Affinity DataIC50: 0.200nMAssay Description:5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [695-745,751-1022,T790M,C797S](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 525486BDBM525486(US11174245, # I-138 | US11174245, # I-136)
Affinity DataIC50: 0.200nMAssay Description:5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [695-745,751-1022,T790M,C797S](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 525547BDBM525547(US11174245, # I-225)
Affinity DataIC50: 0.200nMAssay Description:5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [695-745,751-1022,T790M,C797S](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 525544BDBM525544(US11174245, # I-222)
Affinity DataIC50: 0.200nMAssay Description:5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [695-745,751-1022,T790M,C797S](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 525490BDBM525490(US11174245, # I-143)
Affinity DataIC50: 0.400nMAssay Description:5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [695-745,751-1022,T790M,C797S](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 525543BDBM525543(US11174245, # I-221)
Affinity DataIC50: 0.400nMAssay Description:5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [695-745,751-1022,T790M,C797S](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 525545BDBM525545(US11174245, # I-223)
Affinity DataIC50: 0.5nMAssay Description:5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [695-745,751-1022,T790M,C797S](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 525447BDBM525447(US11174245, # I-032)
Affinity DataIC50: 0.600nMAssay Description:5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [695-745,751-1022,T790M,C797S](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 525446BDBM525446(US11174245, # I-031)
Affinity DataIC50: 1.20nMAssay Description:5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [695-745,751-1022,T790M,C797S](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 525542BDBM525542(US11174245, # I-220)
Affinity DataIC50: 2nMAssay Description:5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [695-745,751-1022,T790M,C797S](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 525432BDBM525432(US11174245, # I-015)
Affinity DataIC50: 2nMAssay Description:5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [695-745,751-1022,T790M,C797S](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 525440BDBM525440(US11174245, # I-024)
Affinity DataIC50: 2.10nMAssay Description:5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [695-745,751-1022,T790M,C797S](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 525443BDBM525443(US11174245, # I-028)
Affinity DataIC50: 2.40nMAssay Description:5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [695-745,751-1022,T790M,C797S](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 525428BDBM525428(US11174245, # I-011)
Affinity DataIC50: 2.5nMAssay Description:5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [695-745,751-1022,T790M,C797S](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 525427BDBM525427(US11174245, # I-010)
Affinity DataIC50: 2.90nMAssay Description:5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [695-745,751-1022,T790M,C797S](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 525445BDBM525445(US11174245, # I-030)
Affinity DataIC50: 3.40nMAssay Description:5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [695-745,751-1022,T790M,C797S](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 525451BDBM525451(US11174245, # I-036)
Affinity DataIC50: 4nMAssay Description:5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [695-745,751-1022,T790M,C797S](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 525459BDBM525459(US11174245, # I-054)
Affinity DataIC50: 4.10nMAssay Description:5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [695-745,751-1022,T790M,C797S](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 525442BDBM525442(US11174245, # I-026)
Affinity DataIC50: 4.40nMAssay Description:5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [695-745,751-1022,T790M,C797S](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 525420BDBM525420(US11174245, # I-002)
Affinity DataIC50: 4.60nMAssay Description:5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [695-745,751-1022,T790M,C797S](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 525422BDBM525422(US11174245, # I-004)
Affinity DataIC50: 4.70nMAssay Description:5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [695-745,751-1022,T790M,C797S](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 525437BDBM525437(US11174245, # I-021)
Affinity DataIC50: 4.90nMAssay Description:5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [695-745,751-1022,T790M,C797S](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 525425BDBM525425(US11174245, # I-008)
Affinity DataIC50: 5nMAssay Description:5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [695-745,751-1022,T790M,C797S](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 525450BDBM525450(US11174245, # I-035)
Affinity DataIC50: 5.60nMAssay Description:5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [695-745,751-1022,T790M,C797S](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 525457BDBM525457(US11174245, # I-052)
Affinity DataIC50: 6.60nMAssay Description:5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [695-745,751-1022,T790M,C797S](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 525424BDBM525424(US11174245, # I-007)
Affinity DataIC50: 7.20nMAssay Description:5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [695-745,751-1022,T790M,C797S](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 525460BDBM525460(US11174245, # I-055)
Affinity DataIC50: 7.30nMAssay Description:5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [695-745,751-1022,T790M,C797S](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 525439BDBM525439(US11174245, # I-023)
Affinity DataIC50: 7.70nMAssay Description:5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [695-745,751-1022,T790M,C797S](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 525448BDBM525448(US11174245, # I-033)
Affinity DataIC50: 8.60nMAssay Description:5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [695-745,751-1022,T790M,C797S](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 525458BDBM525458(US11174245, # I-053)
Affinity DataIC50: 8.70nMAssay Description:5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [695-745,751-1022,T790M,C797S](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 525421BDBM525421(US11174245, # I-003)
Affinity DataIC50: 9.90nMAssay Description:5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [695-745,751-1022,T790M,C797S](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 525429BDBM525429(US11174245, # I-012)
Affinity DataIC50: 10.5nMAssay Description:5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [695-745,751-1022,T790M,C797S](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 525433BDBM525433(US11174245, # I-017)
Affinity DataIC50: 14.2nMAssay Description:5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [695-745,751-1022,T790M,C797S](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 525452BDBM525452(US11174245, # I-037)
Affinity DataIC50: 14.2nMAssay Description:5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [695-745,751-1022,T790M,C797S](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 525423BDBM525423(US11174245, # I-005)
Affinity DataIC50: 14.2nMAssay Description:5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [695-745,751-1022,T790M,C797S](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 525453BDBM525453(US11174245, # I-038)
Affinity DataIC50: 15.8nMAssay Description:5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [695-745,751-1022,T790M,C797S](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 525430BDBM525430(US11174245, # I-013)
Affinity DataIC50: 18.4nMAssay Description:5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [695-745,751-1022,T790M,C797S](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 525449BDBM525449(US11174245, # I-034)
Affinity DataIC50: 22.8nMAssay Description:5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [695-745,751-1022,T790M,C797S](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 525435BDBM525435(US11174245, # I-019)
Affinity DataIC50: 26.3nMAssay Description:5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [695-745,751-1022,T790M,C797S](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 525441BDBM525441(US11174245, # I-025)
Affinity DataIC50: 27.9nMAssay Description:5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [695-745,751-1022,T790M,C797S](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 525454BDBM525454(US11174245, # I-039)
Affinity DataIC50: 36nMAssay Description:5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [695-745,751-1022,T790M,C797S](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 525436BDBM525436(US11174245, # I-020)
Affinity DataIC50: 38.6nMAssay Description:5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [695-745,751-1022,T790M,C797S](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 525431BDBM525431(US11174245, # I-014)
Affinity DataIC50: 48.8nMAssay Description:5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [695-745,751-1022,T790M,C797S](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 525426BDBM525426(US11174245, # I-009)
Affinity DataIC50: 49nMAssay Description:5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [695-745,751-1022,T790M,C797S](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 50505843BDBM50505843(CHEMBL4449589 | US11174245, # I-235)
Affinity DataIC50: 57.2nMAssay Description:5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [695-745,751-1022,T790M,C797S](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 525438BDBM525438(US11174245, # I-022)
Affinity DataIC50: 61.8nMAssay Description:5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [695-745,751-1022,T790M,C797S](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 50505839BDBM50505839(CHEMBL4525935 | US11174245, # I-001)
Affinity DataIC50: 71.7nMAssay Description:5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [695-745,751-1022,T790M,C797S](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 525444BDBM525444(US11174245, # I-029)
Affinity DataIC50: 72.4nMAssay Description:5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent