Compile Data Set for Download or QSAR
Report error Found 682 Enz. Inhib. hit(s) with Target = 'Fatty acid-binding protein 5'
TargetFatty acid-binding protein 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50212876(2,3-bis[(2,4-dichlorobenzyl)oxy]benzoic acid | CHE...)
Affinity DataKi:  2nMAssay Description:Displacement of 1,8-ANS from eFABP by fluorescence based-assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFatty acid-binding protein 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50192463(2-(2,3-bis(2-chlorobenzyloxy)phenyl)acetic acid | ...)
Affinity DataKi:  3nMAssay Description:Binding affinity to human kFABPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFatty acid-binding protein 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50192465(2-(2,3-bis(2-chlorobenzyloxy)phenyl)-2-methoxyacet...)
Affinity DataKi:  9nMAssay Description:Binding affinity to human kFABPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFatty acid-binding protein 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM312447(US9604977, Example 193 | 2-[6-Ethyl-3-(4-methyl-th...)
Affinity DataIC50: 10nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent

TargetFatty acid-binding protein 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM312347(US9604977, Example 93 | 3-[3-(3-Cyclopropyl-[1,2,4...)
Affinity DataIC50: 10nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent

TargetFatty acid-binding protein 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM489718(US10968163, Compound 3l-D)
Affinity DataKi:  10nMAssay Description:FABP5 was purified and delipidated as described previously (Kaczocha, M. et al. 2012). FABP5 (30 μg), NBD-stearate (1 μM), and a competitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2021
Entry Details
US Patent

TargetFatty acid-binding protein 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM312356(US9604977, Example 102 | 2-[3-(3-Cyclopropyl-[1,2,...)
Affinity DataIC50: 10nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent

TargetFatty acid-binding protein 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM312342(US9604977, Example 88 | 2-[3-(3-Cyclopropyl-[1,2,4...)
Affinity DataIC50: 10nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent

TargetFatty acid-binding protein 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM312420(US9604977, Example 166 | 2-[3-(3-Cyclopropyl-[1,2,...)
Affinity DataIC50: 13nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent

TargetFatty acid-binding protein 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM312421(US9604977, Example 167 | 2-[(S)-3-(3-Cyclopropyl-[...)
Affinity DataIC50: 13nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent

TargetFatty acid-binding protein 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM234709(US9353102, 4.15)
Affinity DataIC50: 16nMpH: 7.5Assay Description:Stock DMSO solutions (1.8 mM) of compounds were serially diluted 3-fold for ten concentrations with 100% DMSO (50 μM to 0.003 μM final comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details
US Patent

TargetFatty acid-binding protein 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM312422(US9604977, Example 168 | 2-[(R)-3-(3-Cyclopropyl-[...)
Affinity DataIC50: 18nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent

TargetFatty acid-binding protein 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM312472(US9604977, Example 218 | 2-[3-(3-Cyclopropyl-[1,2,...)
Affinity DataIC50: 19nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent

TargetFatty acid-binding protein 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM312401(US9604977, Example 147 | 2-[6,6-Difluoro-3-(3-trif...)
Affinity DataIC50: 20nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent

TargetFatty acid-binding protein 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM312346(US9604977, Example 92 | 2-[3-(3-Cyclopropyl-[1,2,4...)
Affinity DataIC50: 20nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent

TargetFatty acid-binding protein 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM312330(US9604977, Example 77 | 2-[4,4-Dimethyl-3-(3-methy...)
Affinity DataIC50: 20nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent

TargetFatty acid-binding protein 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM312338(US9604977, Example 85 | 2-[3-(4-Trifluoromethyl-th...)
Affinity DataIC50: 20nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent

TargetFatty acid-binding protein 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM312363(US9604977, Example 109 | (−)-2-[3-(3-Cyclopr...)
Affinity DataIC50: 20nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent

TargetFatty acid-binding protein 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM312313(US9604977, Example 61 | 2-[3-(3-Trifluoromethyl-[1...)
Affinity DataIC50: 20nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent

TargetFatty acid-binding protein 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM489717(US10968163, Compound 3l-C)
Affinity DataKi:  20nMAssay Description:FABP5 was purified and delipidated as described previously (Kaczocha, M. et al. 2012). FABP5 (30 μg), NBD-stearate (1 μM), and a competitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2021
Entry Details
US Patent

TargetFatty acid-binding protein 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM312340(US9604977, Example 86 | 2-[3-(4-Trifluoromethyl-th...)
Affinity DataIC50: 20nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent

TargetFatty acid-binding protein 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50615292(CHEMBL5278217)
Affinity DataIC50: 20nMAssay Description:Inhibition of human FABP5More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetFatty acid-binding protein 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM312405(US9604977, Example 151 | 2-[6,6-Difluoro-3-(4-meth...)
Affinity DataIC50: 20nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent

TargetFatty acid-binding protein 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM489714(US10968163, Compound 3l)
Affinity DataKi:  20nMAssay Description:FABP5 was purified and delipidated as described previously (Kaczocha, M. et al. 2012). FABP5 (30 μg), NBD-stearate (1 μM), and a competitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2021
Entry Details
US Patent

TargetFatty acid-binding protein 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM312442(US9604977, Example 188 | 2-[3-(4-Methyl-thiazol-2-...)
Affinity DataIC50: 22nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent

TargetFatty acid-binding protein 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM234707(US9353102, 4.13)
Affinity DataIC50: 22nMpH: 7.5Assay Description:Stock DMSO solutions (1.8 mM) of compounds were serially diluted 3-fold for ten concentrations with 100% DMSO (50 μM to 0.003 μM final comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details
US Patent

TargetFatty acid-binding protein 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM234703(US9353102, 4.9)
Affinity DataIC50: 22nMpH: 7.5Assay Description:Stock DMSO solutions (1.8 mM) of compounds were serially diluted 3-fold for ten concentrations with 100% DMSO (50 μM to 0.003 μM final comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details
US Patent

TargetFatty acid-binding protein 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM234682(US9353102, 5)
Affinity DataIC50: 30nMpH: 7.5Assay Description:Stock DMSO solutions (1.8 mM) of compounds were serially diluted 3-fold for ten concentrations with 100% DMSO (50 μM to 0.003 μM final comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details
US Patent

TargetFatty acid-binding protein 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM312378(US9604977, Example 124 | 2-[3-(3-Cyclopropyl-[1,2,...)
Affinity DataIC50: 30nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent

TargetFatty acid-binding protein 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM312372(US9604977, Example 118 | 2-[5-(3-Cyclopropyl-[1,2,...)
Affinity DataIC50: 30nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent

TargetFatty acid-binding protein 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM312404(US9604977, Example 150 | 2-[6,6-Difluoro-3-(4-meth...)
Affinity DataIC50: 30nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent

TargetFatty acid-binding protein 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM312341(US9604977, Example 87 | 3-[3-(4-Trifluoromethyl-th...)
Affinity DataIC50: 30nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent

TargetFatty acid-binding protein 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM312357(US9604977, Example 103 | 3-[3-(3-Cyclopropyl-[1,2,...)
Affinity DataIC50: 30nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent

TargetFatty acid-binding protein 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM312485(US9604977, Example 231 | 2-[6,6-Difluoro-3-(4-isop...)
Affinity DataIC50: 30nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent

TargetFatty acid-binding protein 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM234681(US9353102, 4.5)
Affinity DataIC50: 30nMpH: 7.5Assay Description:Stock DMSO solutions (1.8 mM) of compounds were serially diluted 3-fold for ten concentrations with 100% DMSO (50 μM to 0.003 μM final comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details
US Patent

TargetFatty acid-binding protein 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM234678(US9353102, 4.2)
Affinity DataIC50: 30nMpH: 7.5Assay Description:Stock DMSO solutions (1.8 mM) of compounds were serially diluted 3-fold for ten concentrations with 100% DMSO (50 μM to 0.003 μM final comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details
US Patent

TargetFatty acid-binding protein 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM234674(US9353102, 3.3)
Affinity DataIC50: 30nMpH: 7.5Assay Description:Stock DMSO solutions (1.8 mM) of compounds were serially diluted 3-fold for ten concentrations with 100% DMSO (50 μM to 0.003 μM final comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details
US Patent

TargetFatty acid-binding protein 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM312386(US9604977, Example 132 | 2-[3-(3-Cyclopropyl-[1,2,...)
Affinity DataIC50: 30nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent

TargetFatty acid-binding protein 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM234704(US9353102, 4.10)
Affinity DataIC50: 30nMpH: 7.5Assay Description:Stock DMSO solutions (1.8 mM) of compounds were serially diluted 3-fold for ten concentrations with 100% DMSO (50 μM to 0.003 μM final comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details
US Patent

TargetFatty acid-binding protein 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50615291(CHEMBL5287082)
Affinity DataIC50: 30nMAssay Description:Inhibition of human FABP5More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetFatty acid-binding protein 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM312380(US9604977, Example 126 | 2-[3-(3-Trifluoromethyl-[...)
Affinity DataIC50: 30nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent

TargetFatty acid-binding protein 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM312460(US9604977, Example 206 | 2-[3-(3-Cyclopropyl-[1,2,...)
Affinity DataIC50: 30nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent

TargetFatty acid-binding protein 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM489716(US10968163, Compound 3l-B)
Affinity DataKi:  30nMAssay Description:FABP5 was purified and delipidated as described previously (Kaczocha, M. et al. 2012). FABP5 (30 μg), NBD-stearate (1 μM), and a competitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2021
Entry Details
US Patent

TargetFatty acid-binding protein 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM312314(US9604977, Example 62 | 3-[3-(3-Trifluoromethyl-[1...)
Affinity DataIC50: 30nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent

TargetFatty acid-binding protein 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50468465(CHEMBL4288603 | US10968163, Compound 3l-A)
Affinity DataKi:  30nMAssay Description:FABP5 was purified and delipidated as described previously (Kaczocha, M. et al. 2012). FABP5 (30 μg), NBD-stearate (1 μM), and a competitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2021
Entry Details
US Patent

TargetFatty acid-binding protein 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM312333(US9604977, Example 80 | 3-[3-(3-Cyclopropyl-[1,2,4...)
Affinity DataIC50: 30nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent

TargetFatty acid-binding protein 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM312382(US9604977, Example 128 | 3-[3-(3-Trifluoromethyl-[...)
Affinity DataIC50: 30nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent

TargetFatty acid-binding protein 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM312398(US9604977, Example 144 | 2-[3-(3-Cyclopropyl-[1,2,...)
Affinity DataIC50: 30nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent

TargetFatty acid-binding protein 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM234710(US9353102, 4.16)
Affinity DataIC50: 31nMpH: 7.5Assay Description:Stock DMSO solutions (1.8 mM) of compounds were serially diluted 3-fold for ten concentrations with 100% DMSO (50 μM to 0.003 μM final comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details
US Patent

TargetFatty acid-binding protein 5(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM234706(US9353102, 4.12)
Affinity DataIC50: 31nMpH: 7.5Assay Description:Stock DMSO solutions (1.8 mM) of compounds were serially diluted 3-fold for ten concentrations with 100% DMSO (50 μM to 0.003 μM final comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details
US Patent

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