Compile Data Set for Download or QSAR
Report error Found 585 Enz. Inhib. hit(s) with Target = 'Glycogen [starch] synthase, liver'
TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM50529620(CHEMBL4558600)
Affinity DataEC50:  4.10E+3nMAssay Description:Activation of insulin-stimulated glycogen synthase in human HepG2 cells using [U-14C]UDP glucose as substrate preincubated for 18 hrs followed by ins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM50529620(CHEMBL4558600)
Affinity DataEC50:  4.10E+3nMAssay Description:Activation of insulin-stimulated glycogen synthase in human HepG2 cells using [U-14C]UDP glucose as substrate preincubated for 18 hrs followed by ins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM635210(US11814367, Compound 659)
Affinity DataIC50: 1.75E+4nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634938(US11814367, Compound 387)
Affinity DataIC50: 3.62E+4nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM635119(US11814367, Compound 568 | US11814367, Compound 57...)
Affinity DataIC50: 4.12E+4nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM635029(US11814367, Compound 478)
Affinity DataIC50: 6.82E+4nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634926(US11814367, Compound 375)
Affinity DataIC50: 7.74E+4nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634965(US11814367, Compound 414)
Affinity DataIC50: 7.87E+4nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM635129(US11814367, Compound 578)
Affinity DataIC50: 7.93E+4nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634919(US11814367, Compound 368)
Affinity DataIC50: 8.23E+4nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634942(US11814367, Compound 391)
Affinity DataIC50: 8.93E+4nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634940(US11814367, Compound 389)
Affinity DataIC50: 9.03E+4nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM635135(US11814367, Compound 584)
Affinity DataIC50: 9.18E+4nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM635229(US11814367, Compound 678 | US11814367, Compound 68...)
Affinity DataIC50: 9.30E+4nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM635119(US11814367, Compound 568 | US11814367, Compound 57...)
Affinity DataIC50: 9.42E+4nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM635147(US11814367, Compound 596)
Affinity DataIC50: 9.67E+4nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634883(US11814367, Compound 332)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634884(US11814367, Compound 333)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634885(US11814367, Compound 334)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634886(US11814367, Compound 335)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634877(US11814367, Compound 326)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634879(US11814367, Compound 328)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634881(US11814367, Compound 330)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634882(US11814367, Compound 331)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634891(US11814367, Compound 340)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634893(US11814367, Compound 342)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634894(US11814367, Compound 343)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634895(US11814367, Compound 344)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634887(US11814367, Compound 336)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634888(US11814367, Compound 337)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634889(US11814367, Compound 338)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634890(US11814367, Compound 339)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634865(US11814367, Compound 314)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634866(US11814367, Compound 315)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634867(US11814367, Compound 316)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634868(US11814367, Compound 317)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634861(US11814367, Compound 310)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634862(US11814367, Compound 311)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634863(US11814367, Compound 312)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634864(US11814367, Compound 313)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634873(US11814367, Compound 322)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634874(US11814367, Compound 323)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634875(US11814367, Compound 324)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634876(US11814367, Compound 325)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634869(US11814367, Compound 318)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634870(US11814367, Compound 319)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634871(US11814367, Compound 320)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634872(US11814367, Compound 321)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634916(US11814367, Compound 365)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM634917(US11814367, Compound 366)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

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