Compile Data Set for Download or QSAR
Report error Found 126 Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor activator'
TargetHepatocyte growth factor activator(Human)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50512103(CHEMBL4464524)
Affinity DataKi:  3.70nMAssay Description:Inhibition of recombinant HGFA serine protease domain (unknown origin) preincubated for 30 mins followed by Boc-QLR-AMC substrate addition by fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHepatocyte growth factor activator(Human)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50639179(CHEMBL5560415)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of C-terminal 10-His tagged human recombinant HGFA (Gln36 to Ser655 residues) using Boc-QLR-AMC as substrate preincubated for 30 mins foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHepatocyte growth factor activator(Human)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50512105(CHEMBL4587327)
Affinity DataKi:  7.20nMAssay Description:Inhibition of recombinant HGFA serine protease domain (unknown origin) preincubated for 30 mins followed by Boc-QLR-AMC substrate addition by fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHepatocyte growth factor activator(Human)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50639177(CHEMBL5564865)
Affinity DataIC50: 12nMAssay Description:Inhibition of C-terminal 10-His tagged human recombinant HGFA (Gln36 to Ser655 residues) using Boc-QLR-AMC as substrate preincubated for 30 mins foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHepatocyte growth factor activator(Human)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50032991(CHEMBL3356596)
Affinity DataKi:  12nMAssay Description:Inhibition of recombinant HGFA (unknown origin) using Boc-QLR-AMC as substrate by chromogenic proteolytic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetHepatocyte growth factor activator(Human)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50032947(CHEMBL3356606)
Affinity DataKi:  17nMAssay Description:Inhibition of recombinant HGFA (unknown origin) using Boc-QLR-AMC as substrate by chromogenic proteolytic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetHepatocyte growth factor activator(Human)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50032999(CHEMBL3356597)
Affinity DataKi:  21nMAssay Description:Inhibition of recombinant HGFA (unknown origin) using Boc-QLR-AMC as substrate by chromogenic proteolytic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetHepatocyte growth factor activator(Human)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50032944(CHEMBL3356603)
Affinity DataKi:  24nMAssay Description:Inhibition of recombinant HGFA (unknown origin) using Boc-QLR-AMC as substrate by chromogenic proteolytic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetHepatocyte growth factor activator(Human)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50063698(4-Guanidino-benzoic acid 6-carbamimidoyl-naphthale...)
Affinity DataKi:  25nMAssay Description:Inhibition of recombinant N-terminal His-tagged HGFA (unknown origin) expressed in baculovirus-infected Sf9 cells using Boc-QLR-AMC as substrate incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2016
Entry Details Article
PubMed
TargetHepatocyte growth factor activator(Human)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50063698(4-Guanidino-benzoic acid 6-carbamimidoyl-naphthale...)
Affinity DataKi:  25nMAssay Description:Inhibition of recombinant HGFA (unknown origin) using Boc-QLR-AMC as substrate by chromogenic proteolytic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetHepatocyte growth factor activator(Human)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50580346(CHEMBL5074750)
Affinity DataIC50: 26nMAssay Description:Inhibition of recombinant human HGFA serine protease domain using Boc-QLR-AMC as substrate preincubated for 30 mins followed by substrate addition by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHepatocyte growth factor activator(Human)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50639175(CHEMBL5558547)
Affinity DataIC50: 26nMAssay Description:Inhibition of C-terminal 10-His tagged human recombinant HGFA (Gln36 to Ser655 residues) using Boc-QLR-AMC as substrate preincubated for 30 mins foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHepatocyte growth factor activator(Human)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50518599(CHEMBL4454016)
Affinity DataKi:  30nMAssay Description:Inhibition of HGFA catalytic domain (unknown origin) preincubated for 30 mins followed by Boc-QLR-AMC substrate addition and measured for 1 hr by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetHepatocyte growth factor activator(Human)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50518598(CHEMBL4540950)
Affinity DataKi:  33nMAssay Description:Inhibition of HGFA catalytic domain (unknown origin) preincubated for 30 mins followed by Boc-QLR-AMC substrate addition and measured for 1 hr by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetHepatocyte growth factor activator(Human)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50639180(CHEMBL5559738)
Affinity DataIC50: 33nMAssay Description:Inhibition of C-terminal 10-His tagged human recombinant HGFA (Gln36 to Ser655 residues) using Boc-QLR-AMC as substrate preincubated for 30 mins foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHepatocyte growth factor activator(Human)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50639176(CHEMBL5560759)
Affinity DataIC50: 40nMAssay Description:Inhibition of C-terminal 10-His tagged human recombinant HGFA (Gln36 to Ser655 residues) using Boc-QLR-AMC as substrate preincubated for 30 mins foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHepatocyte growth factor activator(Human)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50032936(CHEMBL3356589)
Affinity DataKi:  53nMAssay Description:Inhibition of recombinant HGFA (unknown origin) using Boc-QLR-AMC as substrate by chromogenic proteolytic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetHepatocyte growth factor activator(Human)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50032941(CHEMBL3356600)
Affinity DataKi:  56nMAssay Description:Inhibition of recombinant HGFA (unknown origin) using Boc-QLR-AMC as substrate by chromogenic proteolytic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetHepatocyte growth factor activator(Human)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50032942(CHEMBL3356601)
Affinity DataKi:  57nMAssay Description:Inhibition of recombinant HGFA (unknown origin) using Boc-QLR-AMC as substrate by chromogenic proteolytic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetHepatocyte growth factor activator(Human)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50032933(CHEMBL3356592)
Affinity DataKi:  58nMAssay Description:Inhibition of recombinant HGFA (unknown origin) using Boc-QLR-AMC as substrate by chromogenic proteolytic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetHepatocyte growth factor activator(Human)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50032931(CHEMBL3356594)
Affinity DataKi:  60nMAssay Description:Inhibition of recombinant HGFA (unknown origin) using Boc-QLR-AMC as substrate by chromogenic proteolytic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetHepatocyte growth factor activator(Human)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50639183(CHEMBL5568169)
Affinity DataIC50: 61nMAssay Description:Inhibition of C-terminal 10-His tagged human recombinant HGFA (Gln36 to Ser655 residues) using Boc-QLR-AMC as substrate preincubated for 30 mins foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHepatocyte growth factor activator(Human)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50032946(CHEMBL3356605)
Affinity DataKi:  63nMAssay Description:Inhibition of recombinant HGFA (unknown origin) using Boc-QLR-AMC as substrate by chromogenic proteolytic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetHepatocyte growth factor activator(Human)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50032934(CHEMBL3356591)
Affinity DataKi:  65nMAssay Description:Inhibition of recombinant HGFA (unknown origin) using Boc-QLR-AMC as substrate by chromogenic proteolytic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetHepatocyte growth factor activator(Human)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50032943(CHEMBL3356602)
Affinity DataKi:  79nMAssay Description:Inhibition of recombinant HGFA (unknown origin) using Boc-QLR-AMC as substrate by chromogenic proteolytic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetHepatocyte growth factor activator(Human)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50032932(CHEMBL3356593)
Affinity DataKi:  80nMAssay Description:Inhibition of recombinant HGFA (unknown origin) using Boc-QLR-AMC as substrate by chromogenic proteolytic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetHepatocyte growth factor activator(Human)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50032939(CHEMBL3356598)
Affinity DataKi:  81nMAssay Description:Inhibition of recombinant HGFA (unknown origin) using Boc-QLR-AMC as substrate by chromogenic proteolytic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetHepatocyte growth factor activator(Human)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50639178(CHEMBL5557087)
Affinity DataIC50: 85nMAssay Description:Inhibition of C-terminal 10-His tagged human recombinant HGFA (Gln36 to Ser655 residues) using Boc-QLR-AMC as substrate preincubated for 30 mins foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHepatocyte growth factor activator(Human)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50032935(CHEMBL3356590)
Affinity DataKi:  96nMAssay Description:Inhibition of recombinant HGFA (unknown origin) using Boc-QLR-AMC as substrate by chromogenic proteolytic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetHepatocyte growth factor activator(Human)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50032945(CHEMBL3356604)
Affinity DataKi:  103nMAssay Description:Inhibition of recombinant HGFA (unknown origin) using Boc-QLR-AMC as substrate by chromogenic proteolytic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetHepatocyte growth factor activator(Human)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50063698(4-Guanidino-benzoic acid 6-carbamimidoyl-naphthale...)
Affinity DataIC50: 150nMAssay Description:Inhibition of recombinant N-terminal His-tagged HGFA (unknown origin) expressed in baculovirus-infected Sf9 cells incubated for 30 mins prior to crom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2016
Entry Details Article
PubMed
TargetHepatocyte growth factor activator(Human)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50158157(CHEMBL3780434)
Affinity DataKi:  160nMAssay Description:Inhibition of human recombinant hepatocyte growth factor activator using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2017
Entry Details Article
PubMed
TargetHepatocyte growth factor activator(Human)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50033031(CHEMBL3356607)
Affinity DataEC50:  180nMAssay Description:Inhibition of HGFA in human MDA-MB-231 cells assessed as inhibition of c-MET phosphorylation after 15 mins by immunoblottingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetHepatocyte growth factor activator(Human)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50032930(CHEMBL3356595)
Affinity DataKi:  182nMAssay Description:Inhibition of recombinant HGFA (unknown origin) using Boc-QLR-AMC as substrate by chromogenic proteolytic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetHepatocyte growth factor activator(Human)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50286441(Ac-LLR-CHO | Ac-Leu-Leu-Arg-H | (S)-2-((S)-2-Acety...)
Affinity DataKi:  188nMAssay Description:Inhibition of recombinant HGFA (unknown origin) using Boc-QLR-AMC as substrate by chromogenic proteolytic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetHepatocyte growth factor activator(Human)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50158155(CHEMBL3781354)
Affinity DataKi:  230nMAssay Description:Inhibition of human recombinant hepatocyte growth factor activator using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2017
Entry Details Article
PubMed
TargetHepatocyte growth factor activator(Human)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50639184(CHEMBL5557551)
Affinity DataIC50: 250nMAssay Description:Inhibition of C-terminal 10-His tagged human recombinant HGFA (Gln36 to Ser655 residues) using Boc-QLR-AMC as substrate preincubated for 30 mins foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHepatocyte growth factor activator(Human)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50069128(CHEMBL3403524)
Affinity DataIC50: 300nMAssay Description:Inhibition of recombinant N-terminal His-tagged HGFA (unknown origin) expressed in baculovirus-infected Sf9 cells incubated for 30 mins prior to crom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2016
Entry Details Article
PubMed
TargetHepatocyte growth factor activator(Human)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50032940(CHEMBL3356599)
Affinity DataKi:  332nMAssay Description:Inhibition of recombinant HGFA (unknown origin) using Boc-QLR-AMC as substrate by chromogenic proteolytic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetHepatocyte growth factor activator(Human)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50158151(CHEMBL3780273)
Affinity DataKi:  350nMAssay Description:Inhibition of human recombinant hepatocyte growth factor activator using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2017
Entry Details Article
PubMed
TargetHepatocyte growth factor activator(Human)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50158153(CHEMBL3780548)
Affinity DataKi:  380nMAssay Description:Inhibition of human recombinant hepatocyte growth factor activator using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2017
Entry Details Article
PubMed
TargetHepatocyte growth factor activator(Human)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50158159(CHEMBL3780036)
Affinity DataKi:  430nMAssay Description:Inhibition of human recombinant hepatocyte growth factor activator using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2017
Entry Details Article
PubMed
TargetHepatocyte growth factor activator(Human)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50158101(CHEMBL3781673)
Affinity DataKi:  440nMAssay Description:Inhibition of human recombinant hepatocyte growth factor activator using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2017
Entry Details Article
PubMed
TargetHepatocyte growth factor activator(Human)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50518608(CHEMBL4561858)
Affinity DataKi:  468nMAssay Description:Inhibition of HGFA catalytic domain (unknown origin) preincubated for 30 mins followed by Boc-QLR-AMC substrate addition and measured for 1 hr by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetHepatocyte growth factor activator(Human)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50157632(CHEMBL3781349)
Affinity DataKi:  480nMAssay Description:Inhibition of human recombinant hepatocyte growth factor activator using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2017
Entry Details Article
PubMed
TargetHepatocyte growth factor activator(Human)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50063698(4-Guanidino-benzoic acid 6-carbamimidoyl-naphthale...)
Affinity DataEC50:  490nMAssay Description:Inhibition of HGFA in human MDA-MB-231 cells assessed as inhibition of c-MET phosphorylation after 15 mins by immunoblottingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetHepatocyte growth factor activator(Human)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50158150(CHEMBL3780005)
Affinity DataKi:  520nMAssay Description:Inhibition of human recombinant hepatocyte growth factor activator using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2017
Entry Details Article
PubMed
TargetHepatocyte growth factor activator(Human)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50069105(CHEMBL3403520)
Affinity DataKi:  590nMAssay Description:Inhibition of HGFA (unknown origin) after 40 mins by Eadie-Hofstee plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2016
Entry Details Article
PubMed
TargetHepatocyte growth factor activator(Human)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50069127(CHEMBL3403525)
Affinity DataIC50: 600nMAssay Description:Inhibition of recombinant N-terminal His-tagged HGFA (unknown origin) expressed in baculovirus-infected Sf9 cells incubated for 30 mins prior to crom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2016
Entry Details Article
PubMed
TargetHepatocyte growth factor activator(Human)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50069132(CHEMBL550687)
Affinity DataIC50: 820nMAssay Description:Inhibition of recombinant N-terminal His-tagged HGFA (unknown origin) expressed in baculovirus-infected Sf9 cells incubated for 30 mins prior to crom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2016
Entry Details Article
PubMed
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