Compile Data Set for Download or QSAR
Report error Found 1365 Enz. Inhib. hit(s) with Target = 'Histone deacetylase 11'
TargetHistone deacetylase 11(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50105327(JNJ-26481585 | Quisinostat)
Affinity DataKi:  0.0700nMAssay Description:Inhibition of human HDAC11More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2016
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50101331(CHEMBL3329621)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of HDAC11 (unknown origin) incubated for 3 hrs in presence of BSA and DTT by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50101330(CHEMBL3329622)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of HDAC11 (unknown origin) incubated for 3 hrs in presence of BSA and DTT by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50354086(FK-228 | Istodax | ROMIDEPSIN)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of HDAC11 (unknown origin) incubated for 3 hrs in presence of BSA and DTT by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM19151(Depsipeptide | (1S,4S,7Z,10S,16E,21R)-7-ethylidene...)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of HDAC11 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 11(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50048864(CHEMBL3310505)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of HDAC11 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50105327(JNJ-26481585 | Quisinostat)
Affinity DataIC50: 0.370nMAssay Description:Inhibition of HDAC11 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 11(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50105327(JNJ-26481585 | Quisinostat)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human HDAC11 expressed in baculovirus infected sf9 cells using (Boc-Lys(trifluoroacetyl)-AMC) as substrate by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50649001(CHEMBL5618885)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of HDAC11 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 11(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50273535(CHEMBL4130288 | US11535607, Example 18-1)
Affinity DataIC50: 1nMAssay Description:Inhibition of full length recombinant human HDAC11 expressed in baculoviral expression system using FAM-RHKK as substrate by electrophoretic mobility...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2020
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50027494(CHEMBL3356916)
Affinity DataIC50: 1nMAssay Description:Inhibition of HDAC11 (unknown origin) using fluorogenic tetrapeptide RHKK(Ac) substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM29589(Panobinostat | Faridak | LBH-589B | LBH-589 | US10...)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of HDAC11 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50273525(CHEMBL4128972 | US11535607, Example 18-2)
Affinity DataIC50: 2nMAssay Description:Inhibition of full length recombinant human HDAC11 expressed in baculoviral expression system using FAM-RHKK as substrate by electrophoretic mobility...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2020
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50273553(CHEMBL4127020 | US10508088, ID HDTK028 | US1153560...)
Affinity DataIC50: 2nMAssay Description:Inhibition of full length recombinant human HDAC11 expressed in baculoviral expression system using FAM-RHKK as substrate by electrophoretic mobility...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2020
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50273522(CHEMBL4127743 | US11535607, Example 12-1)
Affinity DataIC50: 2nMAssay Description:Inhibition of full length recombinant human HDAC11 expressed in baculoviral expression system using FAM-RHKK as substrate by electrophoretic mobility...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2020
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50304782(N-hydroxy-2-(4-(naphthalen-2-ylsulfonyl)piperazin-...)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human HDAC11More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM29589(Panobinostat | Faridak | LBH-589B | LBH-589 | US10...)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of human recombinant HDAC11 using Boc-Lys(triflouroacetyI)-AMC substrate incubated for 2 hrs by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50273526(CHEMBL4126661 | US11535607, Example 22-8)
Affinity DataIC50: 3nMAssay Description:Inhibition of full length recombinant human HDAC11 expressed in baculoviral expression system using FAM-RHKK as substrate by electrophoretic mobility...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2020
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM29589(Panobinostat | Faridak | LBH-589B | LBH-589 | US10...)
Affinity DataIC50: 3nMAssay Description:Inhibition of HDAC11 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetHistone deacetylase 11(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50273520(CHEMBL4127735 | US11535607, Example 22-3)
Affinity DataIC50: 3nMAssay Description:Inhibition of full length recombinant human HDAC11 expressed in baculoviral expression system using FAM-RHKK as substrate by electrophoretic mobility...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2020
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50273553(CHEMBL4127020 | US10508088, ID HDTK028 | US1153560...)
Affinity DataIC50: 3nMAssay Description:This example describes in vitro inhibition properties of exemplary HDAC11 inhibitors for various HDACs. HDAC inhibition assays were performed using a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2020
Entry Details
US Patent

TargetHistone deacetylase 11(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM421500(US10538496, Compound 1-1 | US10508088, Example 1-1...)
Affinity DataIC50: 3nMAssay Description:This example describes in vitro inhibition properties of exemplary HDAC11 inhibitors for various HDACs. HDAC inhibition assays were performed using a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2020
Entry Details
US Patent

TargetHistone deacetylase 11(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50027495(CHEMBL3356917)
Affinity DataIC50: 3nMAssay Description:Inhibition of HDAC11 (unknown origin) using fluorogenic tetrapeptide RHKK(Ac) substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50020912(Largazole Thiol)
Affinity DataIC50: 3nMAssay Description:Inhibition of HDAC11 (unknown origin) incubated for 3 hrs in presence of BSA and in absence of DTT by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM29589(Panobinostat | Faridak | LBH-589B | LBH-589 | US10...)
Affinity DataKi:  3.5nMAssay Description:Competitive inhibition of HDAC11 using KI-104 as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50027521(CHEMBL3356925)
Affinity DataIC50: 4nMAssay Description:Inhibition of HDAC11 (unknown origin) using fluorogenic tetrapeptide RHKK(Ac) substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 4nMAssay Description:Inhibition of HDAC11 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 11(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50353234(CHEMBL1830537)
Affinity DataKi:  4.20nMAssay Description:Competitive inhibition of HDAC11 using KI-104 as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50188961(CHEMBL3622533)
Affinity DataIC50: 5nMAssay Description:Inhibition of HDAC11 (unknown origin) by color de Lys colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50027648(CHEMBL3356526)
Affinity DataIC50: 5nMAssay Description:Inhibition of HDAC11 (unknown origin) using fluorogenic tetrapeptide RHKK(Ac) substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50273538(CHEMBL4127894 | US11535607, Example 22-6)
Affinity DataIC50: 5nMAssay Description:Inhibition of full length recombinant human HDAC11 expressed in baculoviral expression system using FAM-RHKK as substrate by electrophoretic mobility...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2020
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50027501(CHEMBL3356923)
Affinity DataIC50: 5nMAssay Description:Inhibition of HDAC11 (unknown origin) using fluorogenic tetrapeptide RHKK(Ac) substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50188961(CHEMBL3622533)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of full length human recombinant HDAC11 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC as substrate assessed as r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2017
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50188961(CHEMBL3622533)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of HDAC11 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50188961(CHEMBL3622533)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of HDAC11 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 11(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50405632(CHEMBL5278968)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of human HDAC11 by fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetHistone deacetylase 11(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM19428(NVP-LAQ824 | (2E)-N-hydroxy-3-(4-{[(2-hydroxyethyl...)
Affinity DataIC50: 5.60nMAssay Description:Inhibition of human HDAC11 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50027602(CHEMBL3356523)
Affinity DataIC50: 6nMAssay Description:Inhibition of HDAC11 (unknown origin) using fluorogenic tetrapeptide RHKK(Ac) substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50273554(CHEMBL4129134 | US11535607, Example 22-2)
Affinity DataIC50: 6nMAssay Description:Inhibition of full length recombinant human HDAC11 expressed in baculoviral expression system using FAM-RHKK as substrate by electrophoretic mobility...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2020
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50273551(CHEMBL4129143 | US11535607, Example 45-1)
Affinity DataIC50: 7nMAssay Description:Inhibition of full length recombinant human HDAC11 expressed in baculoviral expression system using FAM-RHKK as substrate by electrophoretic mobility...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2020
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50273549(CHEMBL4129266 | US11535607, Example 15-1)
Affinity DataIC50: 7nMAssay Description:Inhibition of full length recombinant human HDAC11 expressed in baculoviral expression system using FAM-RHKK as substrate by electrophoretic mobility...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2020
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM29589(Panobinostat | Faridak | LBH-589B | LBH-589 | US10...)
Affinity DataIC50: 8nMAssay Description:Inhibition of human recombinant HDAC11 using fluorescent peptide p53 (379 to 382 residues) RHKK(Ac) as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 11(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50353233(CHEMBL1830536)
Affinity DataKi:  8.80nMAssay Description:Competitive inhibition of HDAC11 using KI-104 as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50027649(CHEMBL3356527)
Affinity DataIC50: 9nMAssay Description:Inhibition of HDAC11 (unknown origin) using fluorogenic tetrapeptide RHKK(Ac) substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50319209(6-[3-(4-Bromo-benzoyl)-ureido]-hexanoic acid hydro...)
Affinity DataKi:  9nMAssay Description:Inhibition of HDAC11More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50027589(CHEMBL3356929)
Affinity DataIC50: 10nMAssay Description:Inhibition of HDAC11 (unknown origin) using fluorogenic tetrapeptide RHKK(Ac) substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50027633(CHEMBL3356524)
Affinity DataIC50: 10nMAssay Description:Inhibition of HDAC11 (unknown origin) using fluorogenic tetrapeptide RHKK(Ac) substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant HDAC11 using fluorogenic class IIa (Bos-Lys(trifluoroacetyl)-AMC) as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetHistone deacetylase 11(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50005711(GNF-Pf-1011 | CHEBI:46024 | TRICHOSTATIN | Trichos...)
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant full-length human HDAC11 using RHKK(Ac) as substrate measured after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50353232(CHEMBL1830424)
Affinity DataKi:  11nMAssay Description:Competitive inhibition of HDAC11 using KI-104 as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
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