Compile Data Set for Download or QSAR
Report error Found 558 Enz. Inhib. hit(s) with Target = 'Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)'
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50511825(CHEMBL4444219)
Affinity DataIC50: 0.173nMAssay Description:Inhibition of recombinant human C-terminal GST/His-tagged HDAC3 (1 to 428 residues) co-expressed with human N-terminal GST-tagged NCOR2 (395 to 489 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50511825(CHEMBL4444219)
Affinity DataIC50: 0.255nMAssay Description:Inhibition of recombinant human C-terminal GST/His-tagged HDAC3 (1 to 428 residues) co-expressed with human N-terminal GST-tagged NCOR2 (395 to 489 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM19130(CHEMBL99 | (2E,4E,6R)-7-[4-(dimethylamino)phenyl]-...)
Affinity DataKi:  0.260nMAssay Description:Displacement of fluorescent 5-(3-(3-(4-((4-((7-(hydroxyamino)-7-oxoheptyl)carbamoyl)phenylamino)methyl)-1H-1,2,3-triazol-1-yl)propyl)thioureido)-2-(3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50511825(CHEMBL4444219)
Affinity DataIC50: 0.280nMAssay Description:Inhibition of recombinant human C-terminal GST/His-tagged HDAC3 (1 to 428 residues) co-expressed with human N-terminal GST-tagged NCOR2 (395 to 489 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50511825(CHEMBL4444219)
Affinity DataIC50: 0.316nMAssay Description:Inhibition of recombinant human C-terminal GST/His-tagged HDAC3 (1 to 428 residues) co-expressed with human N-terminal GST-tagged NCOR2 (395 to 489 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50511825(CHEMBL4444219)
Affinity DataIC50: 0.534nMAssay Description:Inhibition of recombinant human C-terminal GST/His-tagged HDAC3 (1 to 428 residues) co-expressed with human N-terminal GST-tagged NCOR2 (395 to 489 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50555464(CHEMBL4744689)
Affinity DataIC50: 0.660nMAssay Description:Inhibition of recombinant human C-terminal His-tagged HDAC3 (1 to 428 end residues)/N-terminal GST-tagged recombinant human NCoR2 (395 to 489 residue...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50098414(CHEMBL3593247)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of full length human C-terminal His-tagged HDAC3/N-terminal GST-tagged NCOR2 (395 to 489 residues) expressed in baculovirus infected Sf9 i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2019
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50005711(GNF-Pf-1011 | CHEBI:46024 | TRICHOSTATIN | Trichos...)
Affinity DataKi:  0.840nMAssay Description:Inhibition of full length recombinant human C-terminal His-tagged HDAC3/N-terminal GST-tagged recombinant human NCOR2 (395 to 489 residues) expressed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50555461(CHEMBL4749655)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of recombinant human C-terminal His-tagged HDAC3 (1 to 428 end residues)/N-terminal GST-tagged recombinant human NCoR2 (395 to 489 residue...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50244779(CHEMBL4063938)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of full length recombinant human C-terminal His-tagged HDAC3/N-terminal GST-tagged NCOR2 co-expressed in baculovirus expression system usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2019
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50238632((6S,9S,12S,14aR)-6-((S)-sec-Butyl)-9-(1-methoxy-1H...)
Affinity DataKi:  1.5nMAssay Description:Displacement of fluorescent 5-(3-(3-(4-((4-((7-(hydroxyamino)-7-oxoheptyl)carbamoyl)phenylamino)methyl)-1H-1,2,3-triazol-1-yl)propyl)thioureido)-2-(3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM29589(Panobinostat | Faridak | LBH-589B | LBH-589 | US10...)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of recombinant human C-terminal GST/His-tagged HDAC3 (1 to 428 residues) co-expressed with human N-terminal GST-tagged NCOR2 (395 to 489 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50188961(CHEMBL3622533)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of full length C-terminal His-tagged human recombinant HDAC3/NCOR2 (395 to 489 residues) expressed in baculovirus infected insect Sf9 cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2017
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM29589(Panobinostat | Faridak | LBH-589B | LBH-589 | US10...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of recombinant human C-terminal GST/His-tagged HDAC3 (1 to 428 residues) co-expressed with human N-terminal GST-tagged NCOR2 (395 to 489 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50555460(CHEMBL4785064)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human C-terminal His-tagged HDAC3 (1 to 428 end residues)/N-terminal GST-tagged recombinant human NCoR2 (395 to 489 residue...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataKi:  2nMAssay Description:Displacement of fluorescent 5-(3-(3-(4-((4-((7-(hydroxyamino)-7-oxoheptyl)carbamoyl)phenylamino)methyl)-1H-1,2,3-triazol-1-yl)propyl)thioureido)-2-(3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50042847(CHEMBL3098602)
Affinity DataIC50: 2nMAssay Description:Inhibition of human HDAC3/NCOR2 using RHKK(Ac) as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50377687(CHEMBL255686)
Affinity DataKd:  2nMAssay Description:Displacement of fluorescent 5-(3-(3-(4-((4-((7-(hydroxyamino)-7-oxoheptyl)carbamoyl)phenylamino)methyl)-1H-1,2,3-triazol-1-yl)propyl)thioureido)-2-(3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM29589(Panobinostat | Faridak | LBH-589B | LBH-589 | US10...)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of recombinant human C-terminal GST/His-tagged HDAC3 (1 to 428 residues) co-expressed with human N-terminal GST-tagged NCOR2 (395 to 489 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM29589(Panobinostat | Faridak | LBH-589B | LBH-589 | US10...)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of recombinant human C-terminal GST/His-tagged HDAC3 (1 to 428 residues) co-expressed with human N-terminal GST-tagged NCOR2 (395 to 489 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM29589(Panobinostat | Faridak | LBH-589B | LBH-589 | US10...)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of recombinant human C-terminal GST/His-tagged HDAC3 (1 to 428 residues) co-expressed with human N-terminal GST-tagged NCOR2 (395 to 489 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50105327(JNJ-26481585 | Quisinostat)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human C-terminal His-tagged HDAC3/N-terminal GST-tagged NCOR2 expressed in baculovirus infected Sf9 cells using Ac-peptide as substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM29589(Panobinostat | Faridak | LBH-589B | LBH-589 | US10...)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of full length C-terminal His-tagged human recombinant HDAC3/NCOR2 (395 to 489 residues) expressed in baculovirus infected insect Sf9 cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2017
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50188891(CHEMBL3828518)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of full length C-terminal His-tagged human recombinant HDAC3/NCOR2 (395 to 489 residues) expressed in baculovirus infected insect Sf9 cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2017
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50188899(CHEMBL3827517)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of full length C-terminal His-tagged human recombinant HDAC3/NCOR2 (395 to 489 residues) expressed in baculovirus infected insect Sf9 cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2017
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50244785(CHEMBL4069908)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of full length recombinant human C-terminal His-tagged HDAC3/N-terminal GST-tagged NCOR2 co-expressed in baculovirus expression system usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2019
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50557369(CHEMBL4763061)
Affinity DataIC50: 3nMAssay Description:Inhibition of human C-terminal His-tagged HDAC3/N-terminal GST-tagged NCOR2 expressed in baculovirus infected Sf9 cells using Ac-peptide as substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50516203(CHEMBL4517151)
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant full length C-terminal His-tagged HDAC3 (1 to 428 residues)/N-terminal GST-tagged NCOR2 (395 to 489 residues) express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM19151(Depsipeptide | (1S,4S,7Z,10S,16E,21R)-7-ethylidene...)
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant HDAC3/NCoR2 using Ac-Lys(Ac)-AMC as substrate after 30 mins by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50342750(N,8-dihydroxy-8-(2-(4-(prop-2-ynyloxy)benzylidene)...)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of full length HDAC3/NCoR2 assessed as 7-amino-4-methylcoumarin release from fluorophore conjugated substrate after 5 mins by fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50515971(CHEMBL4441774)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human recombinant full length C-terminal His-tagged HDAC3 (1 to 428 residues)/N-terminal GST-tagged NCOR2 (395 to 489 residues) express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50188961(CHEMBL3622533)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of recombinant human C-terminal His-tagged HDAC3 (1 to 428 end residues)/N-terminal GST-tagged recombinant human NCoR2 (395 to 489 residue...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50188959(CHEMBL3827894)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of full length C-terminal His-tagged human recombinant HDAC3/NCOR2 (395 to 489 residues) expressed in baculovirus infected insect Sf9 cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2017
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50188637(CHEMBL3827814)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of full length C-terminal His-tagged human recombinant HDAC3/NCOR2 (395 to 489 residues) expressed in baculovirus infected insect Sf9 cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2017
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50250135(CHEMBL4060201)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human recombinant HDAC3 (1 to 428 residues)/N-terminal GST-tagged NCOR2 (395 to 489 residues) expressed in Baculovirus infected insect ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2019
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50188897(CHEMBL3827281)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of full length C-terminal His-tagged human recombinant HDAC3/NCOR2 (395 to 489 residues) expressed in baculovirus infected insect Sf9 cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2017
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50354089(CHEMBL1836144)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of recombinant human HDAC3/NCOR2 using Boc-L-Lys(epsilon-trifluoroacetyl)-AMC as substrate by two-step fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50105327(JNJ-26481585 | Quisinostat)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of C-terminal His-tagged recombinant human HDAC3 (1 to 428 residues)/N-terminal GST-tagged recombinant human NCoR2 (395 to 489 residues) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50105327(JNJ-26481585 | Quisinostat)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of full length recombinant human HDAC3/NCOR2 expressed in baculovirus infected Sf9 cells using RHKK-Ac as substrate by fluorescence analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2018
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50105327(JNJ-26481585 | Quisinostat)
Affinity DataIC50: 5nMAssay Description:Inhibition of human HDAC3/NcoR2 expressed in sf9 cells using p53 residues 379-382 (RHKKAc) as substrate by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50510962(CHEMBL4454646)
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human C-terminal GST/His-tagged HDAC3 (1 to 428 residues) co-expressed with human N-terminal GST-tagged NCOR2 (395 to 489 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50575609(CHEMBL4852593)
Affinity DataIC50: 5nMAssay Description:Inhibition of full length human C-terminal His-tagged HDAC3/human N-terminal GST-agged NCOR2 using fluorogenic acetylated peptide as substrate incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM207629(US9265734, R01 | US9796664, Compound R01)
Affinity DataKi:  5nMAssay Description:Inhibition of recombinant HDAC3 (unknown origin)/NCOR2 (unknown origin) using acetyl-Lys(Ac)-AMC as substrate preincubated for up to 3 hrs followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50510962(CHEMBL4454646)
Affinity DataIC50: 5nMAssay Description:Inhibition of C-terminal His-tagged human HDAC3 (1 to 428 residues)/N-terminal GST tagged human NCOR2 (395 to 489) expressed in baculovirus expressio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50244820(CHEMBL4097567)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of full length recombinant human C-terminal His-tagged HDAC3/N-terminal GST-tagged NCOR2 co-expressed in baculovirus expression system usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2019
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50354087(CHEMBL1836143)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of recombinant human HDAC3/NCOR2 using Boc-L-Lys(epsilon-trifluoroacetyl)-AMC as substrate by two-step fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50244778(CHEMBL4086442)
Affinity DataIC50: 5.60nMAssay Description:Inhibition of full length recombinant human C-terminal His-tagged HDAC3/N-terminal GST-tagged NCOR2 co-expressed in baculovirus expression system usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2019
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50244778(CHEMBL4086442)
Affinity DataIC50: 5.70nMAssay Description:Inhibition of full length recombinant human C-terminal His-tagged HDAC3/N-terminal GST-tagged NCOR2 co-expressed in baculovirus expression system usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2019
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM476626(N-(4-(2-propylhydrazine-1- carbonyl)benzyl)cinnama...)
Affinity DataIC50: 6nMAssay Description:Inhibition of full length C-terminal His-tagged HDAC3 (unknown origin)/N-terminal GST-tagged NCoR2 (unknown origin) using (Ac-Leu-Gly-Lys(Ac)-AMC as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
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