Report error Found 791 Enz. Inhib. hit(s) with Target = 'Interleukin-2'
Affinity DataKd: 0.0290nMAssay Description:Binding affinity to IL-2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:IL-21 levels in cell supernatants and cell-free control samples were measured using the ALPHALISA assay kit from Perkin Elmer, following the manufact...More data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:IL-21 levels in cell supernatants and cell-free control samples were measured using the ALPHALISA assay kit from Perkin Elmer, following the manufact...More data for this Ligand-Target Pair
Affinity DataEC50: 0.609nMAssay Description:Induction of stability of human recombinant interleukin 2 assessed as increase in mouse CTLL-2 cell proliferation measured after 48 hrs by WST-1 assa...More data for this Ligand-Target Pair
Affinity DataIC50: 0.630nMAssay Description:A 384-well plate was coated with 50 pl/well of human IL-23 at a final concentration of 1 pg/ml and incubated overnight at 4°C. The wells were washed ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.690nMAssay Description:A 384-well plate was coated with 50 pl/well of human IL-23 at a final concentration of 1 pg/ml and incubated overnight at 4°C. The wells were washed ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.780nMAssay Description:A 384-well plate was coated with 50 pl/well of human IL-23 at a final concentration of 1 pg/ml and incubated overnight at 4°C. The wells were washed ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:IL-21 levels in cell supernatants and cell-free control samples were measured using the ALPHALISA assay kit from Perkin Elmer, following the manufact...More data for this Ligand-Target Pair
Affinity DataIC50: 0.960nMAssay Description:A 384-well plate was coated with 50 pl/well of human IL-23 at a final concentration of 1 pg/ml and incubated overnight at 4°C. The wells were washed ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.04nMAssay Description:A 384-well plate was coated with 50 pl/well of human IL-23 at a final concentration of 1 pg/ml and incubated overnight at 4°C. The wells were washed ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.21nMAssay Description:A 384-well plate was coated with 50 pl/well of human IL-23 at a final concentration of 1 pg/ml and incubated overnight at 4°C. The wells were washed ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.34nMAssay Description:A 384-well plate was coated with 50 pl/well of human IL-23 at a final concentration of 1 pg/ml and incubated overnight at 4°C. The wells were washed ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.38nMAssay Description:A 384-well plate was coated with 50 pl/well of human IL-23 at a final concentration of 1 pg/ml and incubated overnight at 4°C. The wells were washed ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.44nMAssay Description:A 384-well plate was coated with 50 pl/well of human IL-23 at a final concentration of 1 pg/ml and incubated overnight at 4°C. The wells were washed ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.46nMAssay Description:A 384-well plate was coated with 50 pl/well of human IL-23 at a final concentration of 1 pg/ml and incubated overnight at 4°C. The wells were washed ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.47nMAssay Description:A 384-well plate was coated with 50 pl/well of human IL-23 at a final concentration of 1 pg/ml and incubated overnight at 4°C. The wells were washed ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.55nMAssay Description:A 384-well plate was coated with 50 pl/well of human IL-23 at a final concentration of 1 pg/ml and incubated overnight at 4°C. The wells were washed ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.59nMAssay Description:A 384-well plate was coated with 50 pl/well of human IL-23 at a final concentration of 1 pg/ml and incubated overnight at 4°C. The wells were washed ...More data for this Ligand-Target Pair
Affinity DataKd: 1.81nMAssay Description:Binding affinity to recombinant human flag/His-tagged IL-23R (1 to 353 residues) expressed in HEK293F cells measured over 90 secs by surface plasmon ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.95nMAssay Description:A 384-well plate was coated with 50 pl/well of human IL-23 at a final concentration of 1 pg/ml and incubated overnight at 4°C. The wells were washed ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.96nMAssay Description:A 384-well plate was coated with 50 pl/well of human IL-23 at a final concentration of 1 pg/ml and incubated overnight at 4°C. The wells were washed ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.06nMAssay Description:A 384-well plate was coated with 50 pl/well of human IL-23 at a final concentration of 1 pg/ml and incubated overnight at 4°C. The wells were washed ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.16nMAssay Description:A 384-well plate was coated with 50 pl/well of human IL-23 at a final concentration of 1 pg/ml and incubated overnight at 4°C. The wells were washed ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.47nMAssay Description:A 384-well plate was coated with 50 pl/well of human IL-23 at a final concentration of 1 pg/ml and incubated overnight at 4°C. The wells were washed ...More data for this Ligand-Target Pair
Affinity DataKd: 2.59nMAssay Description:Binding affinity to IL-2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.68nMAssay Description:A 384-well plate was coated with 50 pl/well of human IL-23 at a final concentration of 1 pg/ml and incubated overnight at 4°C. The wells were washed ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:Binding affinity to recombinant human flag/His-tagged IL-23R (1 to 353 residues) expressed in HEK293F cells assessed as disruption of biotinylated IL...More data for this Ligand-Target Pair
Affinity DataIC50: 2.74nMAssay Description:A 384-well plate was coated with 50 pl/well of human IL-23 at a final concentration of 1 pg/ml and incubated overnight at 4°C. The wells were washed ...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Jurkat cells were placed in a 96 well plate (0.5 million cells per well in 1% FBS medium) then a test compound of this invention was added at differe...More data for this Ligand-Target Pair
Affinity DataEC50: 3nMAssay Description:Effective concentration required against phosphorylation of Mammary gland factor/STAT5More data for this Ligand-Target Pair
Affinity DataIC50: 3.11nMAssay Description:A 384-well plate was coated with 50 pl/well of human IL-23 at a final concentration of 1 pg/ml and incubated overnight at 4°C. The wells were washed ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.13nMAssay Description:A 384-well plate was coated with 50 pl/well of human IL-23 at a final concentration of 1 pg/ml and incubated overnight at 4°C. The wells were washed ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.36nMAssay Description:A 384-well plate was coated with 50 pl/well of human IL-23 at a final concentration of 1 pg/ml and incubated overnight at 4°C. The wells were washed ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.55nMAssay Description:A 384-well plate was coated with 50 pl/well of human IL-23 at a final concentration of 1 pg/ml and incubated overnight at 4°C. The wells were washed ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.57nMAssay Description:A 384-well plate was coated with 50 pl/well of human IL-23 at a final concentration of 1 pg/ml and incubated overnight at 4°C. The wells were washed ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.60nMAssay Description:A 384-well plate was coated with 50 pl/well of human IL-23 at a final concentration of 1 pg/ml and incubated overnight at 4°C. The wells were washed ...More data for this Ligand-Target Pair
Affinity DataIC50: 4.55nMAssay Description:A 384-well plate was coated with 50 pl/well of human IL-23 at a final concentration of 1 pg/ml and incubated overnight at 4°C. The wells were washed ...More data for this Ligand-Target Pair
Affinity DataIC50: 4.66nMAssay Description:A 384-well plate was coated with 50 pl/well of human IL-23 at a final concentration of 1 pg/ml and incubated overnight at 4°C. The wells were washed ...More data for this Ligand-Target Pair
Affinity DataIC50: 4.90nMAssay Description:IL-21 levels in cell supernatants and cell-free control samples were measured using the ALPHALISA assay kit from Perkin Elmer, following the manufact...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:The compound was evaluated in vitro for the immunosuppressive activity in interleukin-2 by interleukin-2 reporter gene assay (IL2-RGA)More data for this Ligand-Target Pair
Affinity DataIC50: 5.10nMAssay Description:Binding affinity to recombinant human flag/His-tagged IL-23R (1 to 353 residues) expressed in HEK293F cells assessed as disruption of biotinylated IL...More data for this Ligand-Target Pair
Affinity DataIC50: 5.42nMAssay Description:A 384-well plate was coated with 50 pl/well of human IL-23 at a final concentration of 1 pg/ml and incubated overnight at 4°C. The wells were washed ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.63nMAssay Description:A 384-well plate was coated with 50 pl/well of human IL-23 at a final concentration of 1 pg/ml and incubated overnight at 4°C. The wells were washed ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.74nMAssay Description:A 384-well plate was coated with 50 pl/well of human IL-23 at a final concentration of 1 pg/ml and incubated overnight at 4°C. The wells were washed ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.90nMAssay Description:IL-21 levels in cell supernatants and cell-free control samples were measured using the ALPHALISA assay kit from Perkin Elmer, following the manufact...More data for this Ligand-Target Pair
Affinity DataIC50: 6.24nMAssay Description:A 384-well plate was coated with 50 pl/well of human IL-23 at a final concentration of 1 pg/ml and incubated overnight at 4°C. The wells were washed ...More data for this Ligand-Target Pair
Affinity DataIC50: 6.30nMAssay Description:IL-21 levels in cell supernatants and cell-free control samples were measured using the ALPHALISA assay kit from Perkin Elmer, following the manufact...More data for this Ligand-Target Pair
Affinity DataIC50: 6.40nMAssay Description:Jurkat cells were placed in a 96 well plate (0.5 million cells per well in 1% FBS medium) then a test compound of this invention was added at differe...More data for this Ligand-Target Pair
Affinity DataIC50: 7.87nMAssay Description:A 384-well plate was coated with 50 pl/well of human IL-23 at a final concentration of 1 pg/ml and incubated overnight at 4°C. The wells were washed ...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...More data for this Ligand-Target Pair
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