Compile Data Set for Download or QSAR
Report error Found 272 Enz. Inhib. hit(s) with Target = 'Lysophosphatidic acid receptor 3'
TargetLysophosphatidic acid receptor 3(Human)
The University of Utah

Curated by ChEMBL
LigandPNGBDBM50430007(CHEMBL2335051)
Affinity DataEC50:  0.210nMAssay Description:Agonist activity at human LPA3 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 3(Human)
The University of Utah

Curated by ChEMBL
LigandPNGBDBM50430006(CHEMBL2335048)
Affinity DataEC50:  0.230nMAssay Description:Agonist activity at human LPA3 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 3(Human)
The University of Utah

Curated by ChEMBL
LigandPNGBDBM50430012(CHEMBL357053)
Affinity DataEC50:  0.270nMAssay Description:Agonist activity at human LPA3 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 3(Human)
The University of Utah

Curated by ChEMBL
LigandPNGBDBM50381022(CHEMBL2017139)
Affinity DataEC50:  0.280nMAssay Description:Agonist activity at human LPA3 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 3(Human)
The University of Utah

Curated by ChEMBL
LigandPNGBDBM50430009(CHEMBL2335049)
Affinity DataEC50:  0.360nMAssay Description:Agonist activity at human LPA3 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 3(Human)
The University of Utah

Curated by ChEMBL
LigandPNGBDBM50430010(CHEMBL2335047)
Affinity DataEC50:  0.370nMAssay Description:Agonist activity at human LPA3 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 3(Human)
The University of Utah

Curated by ChEMBL
LigandPNGBDBM50430008(CHEMBL2335050)
Affinity DataEC50:  0.390nMAssay Description:Agonist activity at human LPA3 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 3(Human)
The University of Utah

Curated by ChEMBL
LigandPNGBDBM50430011(CHEMBL153043)
Affinity DataEC50:  0.440nMAssay Description:Agonist activity at human LPA3 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 3(Human)
The University of Utah

Curated by ChEMBL
LigandPNGBDBM50430006(CHEMBL2335048)
Affinity DataEC50:  1.10nMAssay Description:Agonist activity at human LPA3 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 3(Human)
The University of Utah

Curated by ChEMBL
LigandPNGBDBM50176390((R)-O-2,3-bis(octyloxy)propyl O,O-dihydrogen phosp...)
Affinity DataEC50:  3nMAssay Description:Activity at LPA3 receptor transfected RH7777 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 3(Human)
The University of Utah

Curated by ChEMBL
LigandPNGBDBM50176394(octanoic acid (R)-2-octanoyloxy-3-thiophosphonooxy...)
Affinity DataKi:  5nMAssay Description:Activity at LPA3 receptor transfected RH7777 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 3(Human)
The University of Utah

Curated by ChEMBL
LigandPNGBDBM50176394(octanoic acid (R)-2-octanoyloxy-3-thiophosphonooxy...)
Affinity DataIC50: 11nMAssay Description:Activity at LPA3 receptor transfected RH7777 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 3(Human)
The University of Utah

Curated by ChEMBL
LigandPNGBDBM50170852(Thiophosphoric acid (E)-tetradec-9-enyl ester | CH...)
Affinity DataKi:  14nMAssay Description:Binding affinity for Lysophosphatidic acid receptor 3 expressed in RH7777 rat hepatoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 3(Human)
The University of Utah

Curated by ChEMBL
LigandPNGBDBM50170860(Thiophosphoric acid dodecyl ester | CHEMBL191365)
Affinity DataKi:  14nMAssay Description:Binding affinity for Lysophosphatidic acid receptor 3 expressed in RH7777 rat hepatoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 3(Human)
The University of Utah

Curated by ChEMBL
LigandPNGBDBM50170847(Thiophosphoric acid (E)-dodec-9-enyl ester | CHEMB...)
Affinity DataKi:  14nMAssay Description:Binding affinity for Lysophosphatidic acid receptor 3 expressed in RH7777 rat hepatoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 3(Human)
The University of Utah

Curated by ChEMBL
LigandPNGBDBM50271625(2-(2-(2-aminoacetamido)-3-(2,4-dinitrophenylthio)p...)
Affinity DataIC50: 24nMAssay Description:Antagonist activity at LPA3 receptor expressed in rat RH7777 cells assessed as inhibition of LPA-induced intracellular calcium concentrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 3(Human)
The University of Utah

Curated by ChEMBL
LigandPNGBDBM50271625(2-(2-(2-aminoacetamido)-3-(2,4-dinitrophenylthio)p...)
Affinity DataIC50: 24nMAssay Description:Antagonist activity at LPA3 receptor expressed in rat RH7777 cells assessed as inhibition of LPA-induced intracellular calcium responseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 3(Human)
The University of Utah

Curated by ChEMBL
LigandPNGBDBM50170858(Phosphoric acid mono-((E)-dodec-9-enyl) ester | CH...)
Affinity DataKi:  27nMAssay Description:Binding affinity for Lysophosphatidic acid receptor 3 expressed in RH7777 rat hepatoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 3(Human)
The University of Utah

Curated by ChEMBL
LigandPNGBDBM50170847(Thiophosphoric acid (E)-dodec-9-enyl ester | CHEMB...)
Affinity DataIC50: 27nMAssay Description:Inhibition of LPA-induced calcium transients in RH7777 rat hepatoma cells expressing LPA3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 3(Human)
The University of Utah

Curated by ChEMBL
LigandPNGBDBM50170860(Thiophosphoric acid dodecyl ester | CHEMBL191365)
Affinity DataIC50: 28nMAssay Description:Inhibition of LPA-induced calcium transients in RH7777 rat hepatoma cells expressing LPA3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 3(Human)
The University of Utah

Curated by ChEMBL
LigandPNGBDBM50170852(Thiophosphoric acid (E)-tetradec-9-enyl ester | CH...)
Affinity DataIC50: 28nMAssay Description:Inhibition of LPA-induced calcium transients in RH7777 rat hepatoma cells expressing LPA3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 3(Human)
The University of Utah

Curated by ChEMBL
LigandPNGBDBM50271701(2,6-bis(3-carboxyacrylamido)benzoic acid | 4,4'-(2...)
Affinity DataIC50: 30nMAssay Description:Antagonist activity at LPA3 receptor expressed in rat RH7777 cells assessed as inhibition of LPA-induced intracellular calcium responseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 3(Human)
The University of Utah

Curated by ChEMBL
LigandPNGBDBM50271701(2,6-bis(3-carboxyacrylamido)benzoic acid | 4,4'-(2...)
Affinity DataIC50: 30nMAssay Description:Antagonist activity at LPA3 receptor expressed in rat RH7777 cells assessed as inhibition of LPA-induced intracellular calcium concentrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 3(Human)
The University of Utah

Curated by ChEMBL
LigandPNGBDBM50170858(Phosphoric acid mono-((E)-dodec-9-enyl) ester | CH...)
Affinity DataIC50: 32nMAssay Description:Inhibition of LPA-induced calcium transients in RH7777 rat hepatoma cells expressing LPA3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 3(Human)
The University of Utah

Curated by ChEMBL
LigandPNGBDBM50146240(Phosphoric acid mono-[(R)-3-[4-(3-methoxy-benzylox...)
Affinity DataIC50: 36nMAssay Description:In vitro antagonism of LPA-evoked [35S]GTP-gamma-S binding to lysophosphatidic acid receptor 3 in HEK293T cell linesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 3(Human)
The University of Utah

Curated by ChEMBL
LigandPNGBDBM50149996(Phosphoric acid mono-[3-[4-(4-ethoxy-pyridin-2-ylm...)
Affinity DataKi:  39nMAssay Description:Binding affinity towards Lysophosphatidic acid 3 (LPA3) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 3(Human)
The University of Utah

Curated by ChEMBL
LigandPNGBDBM50176391(octanoic acid (R)-2-octanoyloxy-3-phosphonooxy-pro...)
Affinity DataKi:  39nMAssay Description:Activity at LPA3 receptor transfected RH7777 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 3(Human)
The University of Utah

Curated by ChEMBL
LigandPNGBDBM50149997(Phosphoric acid mono-[3-[4-(4-methoxy-3,5-dimethyl...)
Affinity DataKi:  39nMAssay Description:Binding affinity towards Lysophosphatidic acid 3 (LPA3) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 3(Human)
The University of Utah

Curated by ChEMBL
LigandPNGBDBM50373831(CHEMBL272087)
Affinity DataIC50: 40nMAssay Description:Antagonist activity at LPA3 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 3(Human)
The University of Utah

Curated by ChEMBL
LigandPNGBDBM50170851(Phosphoric acid mono-((E)-tetradec-11-enyl) ester ...)
Affinity DataKi:  40nMAssay Description:Binding affinity for Lysophosphatidic acid receptor 3 expressed in RH7777 rat hepatoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 3(Human)
The University of Utah

Curated by ChEMBL
LigandPNGBDBM50150007(Phosphoric acid mono-((R)-2-((Z)-octadec-9-enoylam...)
Affinity DataKi:  48nMAssay Description:Binding affinity towards Lysophosphatidic acid 3 (LPA3) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 3(Human)
The University of Utah

Curated by ChEMBL
LigandPNGBDBM50496698(CHEMBL3218459)
Affinity DataKi:  48nMAssay Description:Competitive antagonist activity at N-terminal 3XHA-tagged human LPA3 receptor overexpressed in CHO cells assessed as inhibition of LPA-induced [35S]G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 3(Human)
The University of Utah

Curated by ChEMBL
LigandPNGBDBM50170857(Thiophosphoric acid decyl ester | CHEMBL187795)
Affinity DataKi:  49nMAssay Description:Binding affinity for Lysophosphatidic acid receptor 3 expressed in RH7777 rat hepatoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 3(Human)
The University of Utah

Curated by ChEMBL
LigandPNGBDBM557823(US11365185, Example 5B | 1-[4-[6-[5-[[6-(3,3-diflu...)
Affinity DataIC50: 49.6nMAssay Description:A cDNA encoding the human LPAR3 receptor is synthesized and cloned into pDNA3 expression plasmid. The plasmid is transfected in U2OS cells using Lipo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetLysophosphatidic acid receptor 3(Human)
The University of Utah

Curated by ChEMBL
LigandPNGBDBM50610651(CHEMBL5277897)
Affinity DataEC50: <50nMAssay Description:Antagonist activity at human LPA3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetLysophosphatidic acid receptor 3(Human)
The University of Utah

Curated by ChEMBL
LigandPNGBDBM50610652(CHEMBL5281669)
Affinity DataEC50: <50nMAssay Description:Antagonist activity at human LPA3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetLysophosphatidic acid receptor 3(Human)
The University of Utah

Curated by ChEMBL
LigandPNGBDBM50610650(CHEMBL5285905)
Affinity DataEC50: <50nMAssay Description:Antagonist activity at human LPA3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetLysophosphatidic acid receptor 3(Human)
The University of Utah

Curated by ChEMBL
LigandPNGBDBM50176397(nonanoic acid (S)-2-nonanoyloxy-3-phosphonooxy-pro...)
Affinity DataKi:  50nMAssay Description:Activity at LPA3 receptor transfected RH7777 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 3(Human)
The University of Utah

Curated by ChEMBL
LigandPNGBDBM50170843(Phosphoric acid mono-((E)-tetradec-9-enyl) ester |...)
Affinity DataKi:  58nMAssay Description:Binding affinity for Lysophosphatidic acid receptor 3 expressed in RH7777 rat hepatoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 3(Human)
The University of Utah

Curated by ChEMBL
LigandPNGBDBM50398090(CHEMBL2182050 | US9321738, 13)
Affinity DataIC50: 65nMAssay Description:Antagonist activity at human recombinant LPA3 expressed in chem-1 cells assessed as inhibition of LPA-induced intracellular calcium mobilization incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 3(Human)
The University of Utah

Curated by ChEMBL
LigandPNGBDBM50398090(CHEMBL2182050 | US9321738, 13)
Affinity DataIC50: 65.7nMT: 2°CAssay Description:Test compounds were prepared by adding 90 μL of HBSS/20 mM HEPES/0.1% BSA buffer to 2 μL of serially diluted compounds. To prepare serial dilut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
US Patent

TargetLysophosphatidic acid receptor 3(Human)
The University of Utah

Curated by ChEMBL
LigandPNGBDBM50170849(Thiophosphoric acid tetradecyl ester | CHEMBL18929...)
Affinity DataKi:  76nMAssay Description:Binding affinity for Lysophosphatidic acid receptor 3 expressed in RH7777 rat hepatoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 3(Human)
The University of Utah

Curated by ChEMBL
LigandPNGBDBM50148348(lysophosphatidic acid | 1-oleoyl lysophosphatidic ...)
Affinity DataEC50:  77nMAssay Description:Agonist activity at human LPA3 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 3(Rat)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50177339(potassium ((2R,4R)-2-(heptadec-9-enyl)-1,3-dioxola...)
Affinity DataKi:  83nMAssay Description:Activity at LPA3 receptor in RH7777 rat hepatoma cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 3(Human)
The University of Utah

Curated by ChEMBL
LigandPNGBDBM50176391(octanoic acid (R)-2-octanoyloxy-3-phosphonooxy-pro...)
Affinity DataIC50: 85nMAssay Description:Activity at LPA3 receptor transfected RH7777 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 3(Human)
The University of Utah

Curated by ChEMBL
LigandPNGBDBM50170843(Phosphoric acid mono-((E)-tetradec-9-enyl) ester |...)
Affinity DataIC50: 96nMAssay Description:Inhibition of LPA-induced calcium transients in RH7777 rat hepatoma cells expressing LPA3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 3(Human)
The University of Utah

Curated by ChEMBL
LigandPNGBDBM50150010(Phosphoric acid mono-[(R)-3-[4-(4-methoxy-pyridin-...)
Affinity DataKi:  102nMAssay Description:Binding affinity towards Lysophosphatidic acid 3 (LPA3) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 3(Human)
The University of Utah

Curated by ChEMBL
LigandPNGBDBM50170851(Phosphoric acid mono-((E)-tetradec-11-enyl) ester ...)
Affinity DataIC50: 103nMAssay Description:Inhibition of LPA-induced calcium transients in RH7777 rat hepatoma cells expressing LPA3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 3(Human)
The University of Utah

Curated by ChEMBL
LigandPNGBDBM50176399(octanoic acid (S)-2-octanoyloxy-3-thiophosphonooxy...)
Affinity DataEC50:  115nMAssay Description:Activity at LPA3 receptor transfected RH7777 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 3(Human)
The University of Utah

Curated by ChEMBL
LigandPNGBDBM50176392(thiophosphoric acid (R)-2-octanoylamino-2-octylcar...)
Affinity DataKi:  118nMAssay Description:Activity at LPA3 receptor transfected RH7777 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Displayed 1 to 50 (of 272 total ) | Next | Last >>
Jump to: