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Report error Found 351 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 13'
TargetMitogen-activated protein kinase 13(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222105(CHEMBL92814)
Affinity DataIC50: 0.600nMAssay Description:Inhibitory activity against mouse Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222094(CHEMBL96305)
Affinity DataIC50: 0.600nMAssay Description:Inhibitory activity against mouse Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50420761(CHEMBL2087507)
Affinity DataIC50: 0.640nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50420769(CHEMBL2087515)
Affinity DataIC50: 0.830nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222098(CHEMBL93161)
Affinity DataIC50: 1.10nMAssay Description:Inhibitory activity against mouse Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM130909(US8822500, Stauro- sporine | US9920060, Staurospor...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human P38d using myelin basic protein as substrate preincubated for 20 mins followed by [gamma-33P]-ATP addition and measured after 120...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 13(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50420767(CHEMBL2087513)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50420746(CHEMBL2087524)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50420763(CHEMBL2087509)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222109(CHEMBL93059)
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against mouse Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222107(CHEMBL93650)
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against mouse Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222101(CHEMBL329635)
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against mouse Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50420756(CHEMBL2087501)
Affinity DataIC50: 2nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222097(CHEMBL92851)
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against mouse Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50420758(CHEMBL2087503)
Affinity DataIC50: 3nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222096(CHEMBL92648)
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against mouse Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222084(CHEMBL327632)
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against mouse Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50420747(CHEMBL2087526)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222110(CHEMBL96629)
Affinity DataIC50: 4nMAssay Description:Inhibitory activity against mouse Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50473629(RPR-238677 | CHEMBL70053)
Affinity DataIC50: 4nMAssay Description:Inhibition of murine Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50473623(RPR-238778 | CHEMBL309802)
Affinity DataIC50: 4nMAssay Description:Inhibition of murine Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50296636(4-chloro-N-cyclopropyl-3-(1-(4-fluorophenyl)-7-met...)
Affinity DataIC50: 4nMAssay Description:Inhibition of p38deltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222100(CHEMBL329005)
Affinity DataIC50: 4.20nMAssay Description:Inhibitory activity against mouse Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50473632(RPR-239457 | CHEMBL71425)
Affinity DataIC50: 5nMAssay Description:Inhibition of murine Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50219254(CHEMBL347592)
Affinity DataIC50: 5nMAssay Description:Inhibition of murine Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222093(CHEMBL178031)
Affinity DataIC50: 5.30nMAssay Description:Inhibitory activity against mouse Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222095(CHEMBL91864)
Affinity DataIC50: 6nMAssay Description:Inhibitory activity against mouse Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM563647(US11407771, Compound 391 | N-(4-{4-[3-(5-tert-Buty...)
Affinity DataIC50: 6nMAssay Description:ach of these analogs were checked for physical chemical characteristics based on molecular weight, Lipinski's Rule of 5, partition coefficient (l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 13(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50473627(RPR-239939 | CHEMBL308203)
Affinity DataIC50: 6nMAssay Description:Inhibition of murine Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50473626(RPR-239938 | CHEMBL71572)
Affinity DataIC50: 6nMAssay Description:Inhibition of murine Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50473625(CHEMBL69319)
Affinity DataIC50: 6nMAssay Description:Inhibition of murine Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50420740(CHEMBL2087742)
Affinity DataIC50: 6.20nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50420766(CHEMBL2087512)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50420749(CHEMBL2087743)
Affinity DataIC50: 6.70nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50420773(CHEMBL2087505)
Affinity DataIC50: 6.70nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50219252(CHEMBL159932)
Affinity DataIC50: 7nMAssay Description:Inhibition of murine Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222099(CHEMBL93140)
Affinity DataIC50: 7nMAssay Description:Inhibitory activity against mouse Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM563618(US11407771, Compound 283 | N-[4-[2-[2-[[5-tert-but...)
Affinity DataIC50: 8nMAssay Description:ach of these analogs were checked for physical chemical characteristics based on molecular weight, Lipinski's Rule of 5, partition coefficient (l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 13(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM563649(US11407771, Compound 394 | N-(4-{4-[3-(5-tert-Buty...)
Affinity DataIC50: 9nMAssay Description:ach of these analogs were checked for physical chemical characteristics based on molecular weight, Lipinski's Rule of 5, partition coefficient (l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 13(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222108(CHEMBL93028)
Affinity DataIC50: 9nMAssay Description:Inhibitory activity against mouse Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM563619(US11407771, Compound 282 | N-[4-[2-[2-[[5-tert-but...)
Affinity DataIC50: 9nMAssay Description:ach of these analogs were checked for physical chemical characteristics based on molecular weight, Lipinski's Rule of 5, partition coefficient (l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 13(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50219253(CHEMBL161197)
Affinity DataIC50: 9nMAssay Description:Inhibition of murine Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50420744(CHEMBL2087522)
Affinity DataIC50: 9.40nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50420750(CHEMBL2087744)
Affinity DataIC50: 10nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50396845(CHEMBL2170294)
Affinity DataIC50: 11nMAssay Description:Inhibition of human MAPK p38alpha by Z'-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222103(CHEMBL329792)
Affinity DataIC50: 11nMAssay Description:Inhibitory activity against mouse Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM563612(US11407771, Compound 331 | Cyclopropanecarboxylic ...)
Affinity DataIC50: 11nMAssay Description:ach of these analogs were checked for physical chemical characteristics based on molecular weight, Lipinski's Rule of 5, partition coefficient (l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 13(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM563650(US11407771, Compound 395 | N-(4-{4-[3-(3-tert-Buty...)
Affinity DataIC50: 11nMAssay Description:ach of these analogs were checked for physical chemical characteristics based on molecular weight, Lipinski's Rule of 5, partition coefficient (l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 13(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50420760(CHEMBL2087506)
Affinity DataIC50: 12nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50473622(RPR-239497 | CHEMBL70705)
Affinity DataIC50: 12nMAssay Description:Inhibition of murine Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
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