Compile Data Set for Download or QSAR
Report error Found 141 Enz. Inhib. hit(s) with Target = 'Non-receptor tyrosine-protein kinase TYK2 [556-871]'
LigandPNGBDBM756288(US12351572, Example 23)
Affinity DataKd: <1nMAssay Description:Streptavidin-coated magnetic beads were treated with biotinylated small molecule ligands for 30 minutes at room temperature to generate affinity resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

LigandPNGBDBM756287(US12351572, Example 22)
Affinity DataKd: <1nMAssay Description:Streptavidin-coated magnetic beads were treated with biotinylated small molecule ligands for 30 minutes at room temperature to generate affinity resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

LigandPNGBDBM756286(US12351572, Example 21)
Affinity DataKd: <1nMAssay Description:Streptavidin-coated magnetic beads were treated with biotinylated small molecule ligands for 30 minutes at room temperature to generate affinity resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

LigandPNGBDBM756285(US12351572, Example 20)
Affinity DataKd: <1nMAssay Description:Streptavidin-coated magnetic beads were treated with biotinylated small molecule ligands for 30 minutes at room temperature to generate affinity resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

LigandPNGBDBM756284(US12351572, Example 19)
Affinity DataKd: <1nMAssay Description:Streptavidin-coated magnetic beads were treated with biotinylated small molecule ligands for 30 minutes at room temperature to generate affinity resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

LigandPNGBDBM756283(US12351572, Example 18)
Affinity DataKd: <1nMAssay Description:Streptavidin-coated magnetic beads were treated with biotinylated small molecule ligands for 30 minutes at room temperature to generate affinity resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

LigandPNGBDBM756282(US12351572, Example 17)
Affinity DataKd: <1nMAssay Description:Streptavidin-coated magnetic beads were treated with biotinylated small molecule ligands for 30 minutes at room temperature to generate affinity resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

LigandPNGBDBM515663(US11053219, Example 33 | US11731956, Example 33 | ...)
Affinity DataKd: <1nMAssay Description:Streptavidin-coated magnetic beads were treated with biotinylated small molecule ligands for 30 minutes at room temperature to generate affinity resi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

LigandPNGBDBM756296(US12351572, Example 32)
Affinity DataKd: <1nMAssay Description:Streptavidin-coated magnetic beads were treated with biotinylated small molecule ligands for 30 minutes at room temperature to generate affinity resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

LigandPNGBDBM515659(US11053219, Example 28 | BDBM515661 | US11053219, ...)
Affinity DataKd: <1nMAssay Description:Streptavidin-coated magnetic beads were treated with biotinylated small molecule ligands for 30 minutes at room temperature to generate affinity resi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

LigandPNGBDBM756294(US12351572, Example 29)
Affinity DataKd: <1nMAssay Description:Streptavidin-coated magnetic beads were treated with biotinylated small molecule ligands for 30 minutes at room temperature to generate affinity resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

LigandPNGBDBM756293(US12351572, Example 28)
Affinity DataKd: <1nMAssay Description:Streptavidin-coated magnetic beads were treated with biotinylated small molecule ligands for 30 minutes at room temperature to generate affinity resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

LigandPNGBDBM515664(US11053219, Example 127 | US11053219, Example 34 |...)
Affinity DataKd: <1nMAssay Description:Streptavidin-coated magnetic beads were treated with biotinylated small molecule ligands for 30 minutes at room temperature to generate affinity resi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

LigandPNGBDBM515657(US11053219, Example 26 | US11731956, Example 26 | ...)
Affinity DataKd: <1nMAssay Description:Streptavidin-coated magnetic beads were treated with biotinylated small molecule ligands for 30 minutes at room temperature to generate affinity resi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

LigandPNGBDBM515656(US11053219, Example 25 | US11731956, Example 25 | ...)
Affinity DataKd: <1nMAssay Description:Streptavidin-coated magnetic beads were treated with biotinylated small molecule ligands for 30 minutes at room temperature to generate affinity resi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

LigandPNGBDBM756273(US12351572, Example 8)
Affinity DataKd: <1nMAssay Description:Streptavidin-coated magnetic beads were treated with biotinylated small molecule ligands for 30 minutes at room temperature to generate affinity resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

LigandPNGBDBM756272(US12351572, Example 7)
Affinity DataKd: <1nMAssay Description:Streptavidin-coated magnetic beads were treated with biotinylated small molecule ligands for 30 minutes at room temperature to generate affinity resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

LigandPNGBDBM756271(US12351572, Example 6)
Affinity DataKd: <1nMAssay Description:Streptavidin-coated magnetic beads were treated with biotinylated small molecule ligands for 30 minutes at room temperature to generate affinity resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

LigandPNGBDBM756270(US12351572, Example 5)
Affinity DataKd: <1nMAssay Description:Streptavidin-coated magnetic beads were treated with biotinylated small molecule ligands for 30 minutes at room temperature to generate affinity resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

LigandPNGBDBM756269(US12351572, Example 4)
Affinity DataKd: <1nMAssay Description:Streptavidin-coated magnetic beads were treated with biotinylated small molecule ligands for 30 minutes at room temperature to generate affinity resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

LigandPNGBDBM756267(US12351572, Example 2)
Affinity DataKd: <1nMAssay Description:Streptavidin-coated magnetic beads were treated with biotinylated small molecule ligands for 30 minutes at room temperature to generate affinity resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

LigandPNGBDBM756266(US12351572, Example 1)
Affinity DataKd: <1nMAssay Description:Streptavidin-coated magnetic beads were treated with biotinylated small molecule ligands for 30 minutes at room temperature to generate affinity resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

LigandPNGBDBM756281(US12351572, Example 16)
Affinity DataKd: <1nMAssay Description:Streptavidin-coated magnetic beads were treated with biotinylated small molecule ligands for 30 minutes at room temperature to generate affinity resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

LigandPNGBDBM756280(US12351572, Example 15)
Affinity DataKd: <1nMAssay Description:Streptavidin-coated magnetic beads were treated with biotinylated small molecule ligands for 30 minutes at room temperature to generate affinity resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

LigandPNGBDBM576244(WO2022109580, Example 3)
Affinity DataIC50: 1nMAssay Description:The probe displacement assay is conducted as follows: In a 384-well plate, test compound along with recombinantly expressed His-tagged protein corres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2022
Entry Details
WIPO WO2022109580

LigandPNGBDBM756279(US12351572, Example 14)
Affinity DataKd: <1nMAssay Description:Streptavidin-coated magnetic beads were treated with biotinylated small molecule ligands for 30 minutes at room temperature to generate affinity resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

LigandPNGBDBM756278(US12351572, Example 13)
Affinity DataKd: <1nMAssay Description:Streptavidin-coated magnetic beads were treated with biotinylated small molecule ligands for 30 minutes at room temperature to generate affinity resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

LigandPNGBDBM756277(US12351572, Example 12)
Affinity DataKd: <1nMAssay Description:Streptavidin-coated magnetic beads were treated with biotinylated small molecule ligands for 30 minutes at room temperature to generate affinity resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

LigandPNGBDBM756276(US12351572, Example 11)
Affinity DataKd: <1nMAssay Description:Streptavidin-coated magnetic beads were treated with biotinylated small molecule ligands for 30 minutes at room temperature to generate affinity resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

LigandPNGBDBM756275(US12351572, Example 10)
Affinity DataKd: <1nMAssay Description:Streptavidin-coated magnetic beads were treated with biotinylated small molecule ligands for 30 minutes at room temperature to generate affinity resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

LigandPNGBDBM756274(US12351572, Example 9)
Affinity DataKd: <1nMAssay Description:Streptavidin-coated magnetic beads were treated with biotinylated small molecule ligands for 30 minutes at room temperature to generate affinity resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

LigandPNGBDBM756318(US12351572, Example 54)
Affinity DataKd: <1nMAssay Description:Streptavidin-coated magnetic beads were treated with biotinylated small molecule ligands for 30 minutes at room temperature to generate affinity resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

LigandPNGBDBM756317(US12351572, Example 53)
Affinity DataKd: <1nMAssay Description:Streptavidin-coated magnetic beads were treated with biotinylated small molecule ligands for 30 minutes at room temperature to generate affinity resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

LigandPNGBDBM515682(US11053219, Example 52 | US11731956, Example 52 | ...)
Affinity DataKd: <1nMAssay Description:Streptavidin-coated magnetic beads were treated with biotinylated small molecule ligands for 30 minutes at room temperature to generate affinity resi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

LigandPNGBDBM515681(US11053219, Example 51 | US11731956, Example 51 | ...)
Affinity DataKd: <1nMAssay Description:Streptavidin-coated magnetic beads were treated with biotinylated small molecule ligands for 30 minutes at room temperature to generate affinity resi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

LigandPNGBDBM756314(US12351572, Example 50)
Affinity DataKd: <1nMAssay Description:Streptavidin-coated magnetic beads were treated with biotinylated small molecule ligands for 30 minutes at room temperature to generate affinity resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

LigandPNGBDBM756328(US12351572, Example 64)
Affinity DataKd: <1nMAssay Description:Streptavidin-coated magnetic beads were treated with biotinylated small molecule ligands for 30 minutes at room temperature to generate affinity resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

LigandPNGBDBM756327(US12351572, Example 63)
Affinity DataKd: <1nMAssay Description:Streptavidin-coated magnetic beads were treated with biotinylated small molecule ligands for 30 minutes at room temperature to generate affinity resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

LigandPNGBDBM756304(US12351572, Example 40)
Affinity DataKd: <1nMAssay Description:Streptavidin-coated magnetic beads were treated with biotinylated small molecule ligands for 30 minutes at room temperature to generate affinity resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

LigandPNGBDBM756302(US12351572, Example 38)
Affinity DataKd: <1nMAssay Description:Streptavidin-coated magnetic beads were treated with biotinylated small molecule ligands for 30 minutes at room temperature to generate affinity resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

LigandPNGBDBM515667(US11053219, Example 37 | US11731956, Example 37 | ...)
Affinity DataKd: <1nMAssay Description:Streptavidin-coated magnetic beads were treated with biotinylated small molecule ligands for 30 minutes at room temperature to generate affinity resi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

LigandPNGBDBM515666(US11053219, Example 36 | US11731956, Example 36 | ...)
Affinity DataKd: <1nMAssay Description:Streptavidin-coated magnetic beads were treated with biotinylated small molecule ligands for 30 minutes at room temperature to generate affinity resi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

LigandPNGBDBM515665(US11053219, Example 35 | US11731956, Example 35 | ...)
Affinity DataKd: <1nMAssay Description:Streptavidin-coated magnetic beads were treated with biotinylated small molecule ligands for 30 minutes at room temperature to generate affinity resi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

LigandPNGBDBM756298(US12351572, Example 34)
Affinity DataKd: <1nMAssay Description:Streptavidin-coated magnetic beads were treated with biotinylated small molecule ligands for 30 minutes at room temperature to generate affinity resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

LigandPNGBDBM756313(US12351572, Example 49)
Affinity DataKd: <1nMAssay Description:Streptavidin-coated magnetic beads were treated with biotinylated small molecule ligands for 30 minutes at room temperature to generate affinity resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

LigandPNGBDBM756312(US12351572, Example 48)
Affinity DataKd: <1nMAssay Description:Streptavidin-coated magnetic beads were treated with biotinylated small molecule ligands for 30 minutes at room temperature to generate affinity resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

LigandPNGBDBM515677(US11053219, Example 47 | US11731956, Example 47 | ...)
Affinity DataKd: <1nMAssay Description:Streptavidin-coated magnetic beads were treated with biotinylated small molecule ligands for 30 minutes at room temperature to generate affinity resi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

LigandPNGBDBM515676(US11053219, Example 46 | US11731956, Example 46 | ...)
Affinity DataKd: <1nMAssay Description:Streptavidin-coated magnetic beads were treated with biotinylated small molecule ligands for 30 minutes at room temperature to generate affinity resi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

LigandPNGBDBM756309(US12351572, Example 45)
Affinity DataKd: <1nMAssay Description:Streptavidin-coated magnetic beads were treated with biotinylated small molecule ligands for 30 minutes at room temperature to generate affinity resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

LigandPNGBDBM756353(US12351572, Example 89)
Affinity DataKd: <1nMAssay Description:Streptavidin-coated magnetic beads were treated with biotinylated small molecule ligands for 30 minutes at room temperature to generate affinity resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

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