Compile Data Set for Download or QSAR
Report error Found 104 Enz. Inhib. hit(s) with Target = 'Non-receptor tyrosine-protein kinase TYK2 [888-1187]'
TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726096([3a(4)Z]-6,9,15,16-tetramethyl- 9,10,11,12-tetrahy...)
Affinity DataKd:  220nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726097([3a(4)Z]-6,9,15,16-tetramethyl- 10,11,13,15-tetrah...)
Affinity DataKd:  1.20nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726098([3a(4)Z,10R]-20-chloro-6,10,15- trimethyl-10,11,13...)
Affinity DataKd:  3nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726099([3a(4)Z,10R]-20-chloro-10,15-dimethyl- 10,11,13,15...)
Affinity DataKd:  1.90nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726100([3a(4)Z,10R]-20-chloro-6,9,10,15- tetramethyl-10,1...)
Affinity DataKd:  0.180nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726101([3a(4)Z,10S]-20-chloro-6,9,10,15- tetramethyl-10,1...)
Affinity DataKd:  2.5nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726102([3a(4)Z]-20-chloro-6,9,15-trimethyl- 10,11,13,15-t...)
Affinity DataKd:  0.510nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726103([3a(4)Z,10R]-20-chloro-6,9,10,15- tetramethyl-10,1...)
Affinity DataKd:  170nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726104([3a(4)Z,10R]-20-chloro-6,9,10,15- tetramethyl-10,1...)
Affinity DataKd:  1nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726105([3a(4)Z,10R]-6,9,10,15-tetramethyl-3,8- dioxo-3,5,...)
Affinity DataKd:  46nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726106([3a(4)Z,10R]-20-fluoro-6,9,10,15,16- pentamethyl-1...)
Affinity DataKd:  3.40nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726107([3a(4)Z,10R]-20-chloro-6,9,10,15,16- pentamethyl-1...)
Affinity DataKd:  1.30nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726108([3a(4)Z,10R]-20-fluoro-6,9,10,15- tetramethyl-10,1...)
Affinity DataKd:  1nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM755066(Synthesis of (7R,E)-31,7-Dimethyl-18-(methylamino)...)
Affinity DataKd:  5.50E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM755067(Synthesis of (7R,E)-7-(Hydroxymethyl)-31-methyl-18...)
Affinity DataKd: <3.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM755068(Synthesis of (7R,E)-3',7-Dimethyl-18-(methylamino)...)
Affinity DataKd: <3.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM755070(Synthesis of (R,13E,14E)-31,7-dimethyl-17-(methyla...)
Affinity DataKd: <3.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM755073((7R,E)-31,7-Dimethyl-18-(methylamino)-31H-5-oxa-2,...)
Affinity DataKd: <3.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM755076((15E,34E,7R)-32,7-dimethyl-18-(methylamino)-32H-5-...)
Affinity DataKd:  5.50E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM755078((7R,E)-3',7-Dimethyl-18-(methylamino)-31H-5-oxa-2,...)
Affinity DataKd:  5.50E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM755086((7R,E)-3',7-Dimethyl-18-(methylamino)-31H-5-oxa-2,...)
Affinity DataKd:  5.50E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM755087((R,13E,14E)-31,7-Dimethyl-17-(methylamino)-31H-5-o...)
Affinity DataKd: <3.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM755088((7R,E)-3',7-Dimethyl-18-(methylamino)-31H-5-oxa-2,...)
Affinity DataKd:  5.50E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM755089((R,13E,14E)-3',7-Dimethyl-17-(methylamino)-31H-5-o...)
Affinity DataKd:  2.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM755090((7R,E)-31,7-Dimethyl-18-(methylamino)-31H-5-oxa-2,...)
Affinity DataKd:  5.50E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM755091((R,13E,14E)-3',7-Dimethyl-17-(methylamino)-31H-5-o...)
Affinity DataKd:  5.50E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM755092((7R,E)-3',7-Dimethyl-18-(methylamino)-31H-5-oxa-2,...)
Affinity DataKd:  2.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM755093(US20250213571, Compound 15)
Affinity DataKd: <3.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM755094(US20250213571, Compound 16)
Affinity DataKd: <3.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM755095(US20250213571, Compound 33)
Affinity DataKd: <3.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM755096(US20250213571, Compound 34)
Affinity DataKd: <3.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM755100(US20250213571, Compound 35)
Affinity DataKd: <3.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM755102(US20250213571, Compound 36)
Affinity DataKd:  5.50E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM755106(US20250213571, Compound 37)
Affinity DataKd: <3.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM755107(US20250213571, Compound 38)
Affinity DataKd: <3.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM755108(US20250213571, Compound 52)
Affinity DataKd:  2.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM755109(US20250213571, Compound 53)
Affinity DataKd:  2.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM755116(US20250213571, Compound 60)
Affinity DataKd:  2.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM755135(US20250213571, Compound 79)
Affinity DataKd: <3.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM755136(US20250213571, Compound 80)
Affinity DataKd: <3.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM755137(US20250213571, Compound 81)
Affinity DataKd: <3.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM755138(US20250213571, Compound 90)
Affinity DataKd: <3.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM755139(US20250213571, Compound 91)
Affinity DataKd:  505nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM755140(US20250213571, Compound 92)
Affinity DataKd: <3.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM755141(US20250213571, Compound 93)
Affinity DataKd: <3.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM755142(US20250213571, Compound 94)
Affinity DataKd: <3.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM755143(US20250213571, Compound 95)
Affinity DataKd: <3.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM755144(US20250213571, Compound 96)
Affinity DataKd:  5.50E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM755145(US20250213571, Compound 97)
Affinity DataKd:  5.50E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM755146(US20250213571, Compound 98)
Affinity DataKd:  505nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent

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