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Report error Found 125 Enz. Inhib. hit(s) with Target = 'Pantothenate kinase 3'
TargetPantothenate kinase 3(Human)TBA
LigandPNGBDBM50586918(CHEMBL5082138)
Affinity DataIC50: 0.220nMAssay Description:Inhibition of PANK3 (unknown origin) using D-[1-14C]pantothenate as substrate incubated for 10 mins in presence of ATP by scintillation counting anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPantothenate kinase 3(Human)TBA
LigandPNGBDBM50586918(CHEMBL5082138)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human recombinant N-terminal His6-fusion tagged PanK3 expressed in Escherichia coli BL21 (DE3) measured after 10 mins in presence of AT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetPantothenate kinase 3(Human)TBA
LigandPNGBDBM50646166(CHEMBL5591518)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of PANK3 (unknown origin) using D-[1-14C]pantothenate as substrate incubated for 10 mins in presence of ATP by scintillation counting anal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPantothenate kinase 3(Human)TBA
LigandPNGBDBM50155166(4-(6-Chloro-pyridazin-3-yl)-piperazine-1-carboxyli...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human recombinant N-terminal His6-fusion tagged PanK3 expressed in Escherichia coli BL21 (DE3) measured after 10 mins in presence of AT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetPantothenate kinase 3(Human)TBA
LigandPNGBDBM50586917(CHEMBL5077276)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant N-terminal His6-fusion tagged PanK3 expressed in Escherichia coli BL21 (DE3) measured after 10 mins in presence of AT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPantothenate kinase 3(Human)TBA
LigandPNGBDBM50646167(CHEMBL5593149)
Affinity DataIC50: 1nMAssay Description:Inhibition of PANK3 (unknown origin) using D-[1-14C]pantothenate as substrate incubated for 10 mins in presence of ATP by scintillation counting anal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPantothenate kinase 3(Human)TBA
LigandPNGBDBM50646165(CHEMBL5579772)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of PANK3 (unknown origin) using D-[1-14C]pantothenate as substrate incubated for 10 mins in presence of ATP by scintillation counting anal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPantothenate kinase 3(Human)TBA
LigandPNGBDBM50586917(CHEMBL5077276)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of PANK3 (unknown origin) using D-[1-14C]pantothenate as substrate incubated for 10 mins in presence of ATP by scintillation counting anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPantothenate kinase 3(Human)TBA
LigandPNGBDBM649472(US11891378, Example 2)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of PANK3 (unknown origin) using D-[1-14C]pantothenate as substrate incubated for 10 mins in presence of ATP by scintillation counting anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPantothenate kinase 3(Human)TBA
LigandPNGBDBM50646152(CHEMBL5595577)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of PANK3 (unknown origin) using D-[1-14C]pantothenate as substrate incubated for 10 mins in presence of ATP by scintillation counting anal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPantothenate kinase 3(Human)TBA
LigandPNGBDBM50646168(CHEMBL5583598)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of PANK3 (unknown origin) using D-[1-14C]pantothenate as substrate incubated for 10 mins in presence of ATP by scintillation counting anal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPantothenate kinase 3(Human)TBA
LigandPNGBDBM50646153(CHEMBL5591881)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of PANK3 (unknown origin) using D-[1-14C]pantothenate as substrate incubated for 10 mins in presence of ATP by scintillation counting anal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPantothenate kinase 3(Human)TBA
LigandPNGBDBM50586915(CHEMBL5094733)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human recombinant N-terminal His6-fusion tagged PanK3 expressed in Escherichia coli BL21 (DE3) measured after 10 mins in presence of AT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPantothenate kinase 3(Human)TBA
LigandPNGBDBM649476(US11891378, Example 6)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of PANK3 (unknown origin) using D-[1-14C]pantothenate as substrate incubated for 10 mins in presence of ATP by scintillation counting anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPantothenate kinase 3(Human)TBA
LigandPNGBDBM649476(US11891378, Example 6)
Affinity DataIC50: 2.20nMAssay Description:The assay is not clearly defined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2024
Entry Details
US Patent

TargetPantothenate kinase 3(Human)TBA
LigandPNGBDBM649472(US11891378, Example 2)
Affinity DataIC50: 2.90nMAssay Description:The assay is not clearly defined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2024
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetPantothenate kinase 3(Human)TBA
LigandPNGBDBM50646171(CHEMBL5593336)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of PANK3 (unknown origin) using D-[1-14C]pantothenate as substrate incubated for 10 mins in presence of ATP by scintillation counting anal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPantothenate kinase 3(Human)TBA
LigandPNGBDBM649480(US11891378, Example 10)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of PANK3 (unknown origin) using D-[1-14C]pantothenate as substrate incubated for 10 mins in presence of ATP by scintillation counting anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPantothenate kinase 3(Human)TBA
LigandPNGBDBM649480(US11891378, Example 10)
Affinity DataIC50: 3.80nMAssay Description:The assay is not clearly defined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2024
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetPantothenate kinase 3(Human)TBA
LigandPNGBDBM50586916(CHEMBL5078496)
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant N-terminal His6-fusion tagged PanK3 expressed in Escherichia coli BL21 (DE3) measured after 10 mins in presence of AT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetPantothenate kinase 3(Human)TBA
LigandPNGBDBM649479(US11891378, Example 9)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of PANK3 (unknown origin) using D-[1-14C]pantothenate as substrate incubated for 10 mins in presence of ATP by scintillation counting anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPantothenate kinase 3(Human)TBA
LigandPNGBDBM649479(US11891378, Example 9)
Affinity DataIC50: 5.20nMAssay Description:The assay is not clearly defined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2024
Entry Details
US Patent

TargetPantothenate kinase 3(Human)TBA
LigandPNGBDBM50646150(CHEMBL5583913)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of PANK3 (unknown origin) using D-[1-14C]pantothenate as substrate incubated for 10 mins in presence of ATP by scintillation counting anal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPantothenate kinase 3(Human)TBA
LigandPNGBDBM50646170(CHEMBL5595772)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of PANK3 (unknown origin) using D-[1-14C]pantothenate as substrate incubated for 10 mins in presence of ATP by scintillation counting anal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPantothenate kinase 3(Human)TBA
LigandPNGBDBM649477(US11891378, Example 7)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of PANK3 (unknown origin) using D-[1-14C]pantothenate as substrate incubated for 10 mins in presence of ATP by scintillation counting anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPantothenate kinase 3(Human)TBA
LigandPNGBDBM649477(US11891378, Example 7)
Affinity DataIC50: 5.80nMAssay Description:The assay is not clearly defined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2024
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetPantothenate kinase 3(Human)TBA
LigandPNGBDBM649473(US11891378, Example 3)
Affinity DataIC50: 6.5nMAssay Description:The assay is not clearly defined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2024
Entry Details
US Patent

TargetPantothenate kinase 3(Human)TBA
LigandPNGBDBM649473(US11891378, Example 3)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of PANK3 (unknown origin) using D-[1-14C]pantothenate as substrate incubated for 10 mins in presence of ATP by scintillation counting anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPantothenate kinase 3(Human)TBA
LigandPNGBDBM649475(US11891378, Example 5)
Affinity DataIC50: 6.90nMAssay Description:Inhibition of PANK3 (unknown origin) using D-[1-14C]pantothenate as substrate incubated for 10 mins in presence of ATP by scintillation counting anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPantothenate kinase 3(Human)TBA
LigandPNGBDBM649475(US11891378, Example 5)
Affinity DataIC50: 6.90nMAssay Description:The assay is not clearly defined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2024
Entry Details
US Patent

TargetPantothenate kinase 3(Human)TBA
LigandPNGBDBM50646151(CHEMBL5591337)
Affinity DataIC50: 7.5nMAssay Description:Inhibition of PANK3 (unknown origin) using D-[1-14C]pantothenate as substrate incubated for 10 mins in presence of ATP by scintillation counting anal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPantothenate kinase 3(Human)TBA
LigandPNGBDBM649471(US11891378, Example 1)
Affinity DataIC50: 8.90nMAssay Description:The assay is not clearly defined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2024
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetPantothenate kinase 3(Human)TBA
LigandPNGBDBM649471(US11891378, Example 1)
Affinity DataIC50: 8.90nMAssay Description:Inhibition of PANK3 (unknown origin) using D-[1-14C]pantothenate as substrate incubated for 10 mins in presence of ATP by scintillation counting anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPantothenate kinase 3(Human)TBA
LigandPNGBDBM50646155(CHEMBL5590407)
Affinity DataIC50: 8.90nMAssay Description:Inhibition of PANK3 (unknown origin) using D-[1-14C]pantothenate as substrate incubated for 10 mins in presence of ATP by scintillation counting anal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPantothenate kinase 3(Human)TBA
LigandPNGBDBM50646163(CHEMBL5589594)
Affinity DataIC50: 9nMAssay Description:Inhibition of PANK3 (unknown origin) using D-[1-14C]pantothenate as substrate incubated for 10 mins in presence of ATP by scintillation counting anal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPantothenate kinase 3(Human)TBA
LigandPNGBDBM50646158(CHEMBL5595986)
Affinity DataIC50: 9.70nMAssay Description:Inhibition of PANK3 (unknown origin) using D-[1-14C]pantothenate as substrate incubated for 10 mins in presence of ATP by scintillation counting anal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPantothenate kinase 3(Human)TBA
LigandPNGBDBM50586913(CHEMBL5085732)
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant N-terminal His6-fusion tagged PanK3 expressed in Escherichia coli BL21 (DE3) measured after 10 mins in presence of AT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetPantothenate kinase 3(Human)TBA
LigandPNGBDBM50586920(CHEMBL5082695)
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant N-terminal His6-fusion tagged PanK3 expressed in Escherichia coli BL21 (DE3) measured after 10 mins in presence of AT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetPantothenate kinase 3(Human)TBA
LigandPNGBDBM649474(US11891378, Example 4)
Affinity DataIC50: 12.5nMAssay Description:The assay is not clearly defined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2024
Entry Details
US Patent

TargetPantothenate kinase 3(Human)TBA
LigandPNGBDBM649478(US11891378, Example 8)
Affinity DataIC50: 12.9nMAssay Description:The assay is not clearly defined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2024
Entry Details
US Patent

TargetPantothenate kinase 3(Human)TBA
LigandPNGBDBM649478(US11891378, Example 8)
Affinity DataIC50: 13nMAssay Description:Inhibition of PANK3 (unknown origin) using D-[1-14C]pantothenate as substrate incubated for 10 mins in presence of ATP by scintillation counting anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPantothenate kinase 3(Human)TBA
LigandPNGBDBM649474(US11891378, Example 4)
Affinity DataIC50: 13nMAssay Description:Inhibition of PANK3 (unknown origin) using D-[1-14C]pantothenate as substrate incubated for 10 mins in presence of ATP by scintillation counting anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPantothenate kinase 3(Human)TBA
LigandPNGBDBM50646160(CHEMBL5593897)
Affinity DataIC50: 17nMAssay Description:Inhibition of PANK3 (unknown origin) using D-[1-14C]pantothenate as substrate incubated for 10 mins in presence of ATP by scintillation counting anal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPantothenate kinase 3(Human)TBA
LigandPNGBDBM50646162(CHEMBL5592747)
Affinity DataIC50: 18nMAssay Description:Inhibition of PANK3 (unknown origin) using D-[1-14C]pantothenate as substrate incubated for 10 mins in presence of ATP by scintillation counting anal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPantothenate kinase 3(Human)TBA
LigandPNGBDBM50646169(CHEMBL5593435)
Affinity DataIC50: 19nMAssay Description:Inhibition of PANK3 (unknown origin) using D-[1-14C]pantothenate as substrate incubated for 10 mins in presence of ATP by scintillation counting anal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPantothenate kinase 3(Human)TBA
LigandPNGBDBM50586901(CHEMBL5093027)
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant N-terminal His6-fusion tagged PanK3 expressed in Escherichia coli BL21 (DE3) measured after 10 mins in presence of AT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetPantothenate kinase 3(Human)TBA
LigandPNGBDBM50646164(CHEMBL5591781)
Affinity DataIC50: 20nMAssay Description:Inhibition of PANK3 (unknown origin) using D-[1-14C]pantothenate as substrate incubated for 10 mins in presence of ATP by scintillation counting anal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPantothenate kinase 3(Human)TBA
LigandPNGBDBM50071456(CHEMBL3410246)
Affinity DataIC50: 25nMAssay Description:Inhibition of purified human Pank3 using d-[1-14C]pantothenate as substrate after 10 mins by radiochemical enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2016
Entry Details Article
PubMed
TargetPantothenate kinase 3(Human)TBA
LigandPNGBDBM50586914(CHEMBL5075383)
Affinity DataIC50: 29nMAssay Description:Inhibition of human recombinant N-terminal His6-fusion tagged PanK3 expressed in Escherichia coli BL21 (DE3) measured after 10 mins in presence of AT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetPantothenate kinase 3(Human)TBA
LigandPNGBDBM50646154(CHEMBL5583789)
Affinity DataIC50: 35nMAssay Description:Inhibition of PANK3 (unknown origin) using D-[1-14C]pantothenate as substrate incubated for 10 mins in presence of ATP by scintillation counting anal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
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