Compile Data Set for Download or QSAR
Report error Found 3639 Enz. Inhib. hit(s) with Target = 'Progesterone receptor'
TargetProgesterone receptor(Human)
Schering

Curated by ChEMBL
LigandPNGBDBM50409115(LONAPRISAN)
Affinity DataIC50: 0.00250nMAssay Description:In vitro antagonist potency in transactivation assay in neuroblastoma cells expressing human PR-B progesterone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Schering

Curated by ChEMBL
LigandPNGBDBM50409115(LONAPRISAN)
Affinity DataIC50: 0.00360nMAssay Description:In vitro antagonist potency in transactivation assay in neuroblastoma cells expressing human PR-A progesterone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Schering

Curated by ChEMBL
LigandPNGBDBM50294714(4-((2-chlorobenzyl)(1-(4-methyl-4H-1,2,4-triazol-3...)
Affinity DataEC50:  0.0200nMAssay Description:Agonist activity at progesterone receptor in human T47D cells by alkaline phosphatase release based reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Schering

Curated by ChEMBL
LigandPNGBDBM50294702(4-((2-chlorobenzyl)(1-(1-methyl-1H-tetrazol-5-yl)e...)
Affinity DataEC50:  0.0200nMAssay Description:Agonist activity at progesterone receptor in human T47D cells by alkaline phosphatase release based reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Schering

Curated by ChEMBL
LigandPNGBDBM18627(Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...)
Affinity DataIC50: 0.0210nMAssay Description:Antagonist activity at progesterone receptor in human T47D-C124 cells transfected with luciferase gene linked to MMTV promoter assessed as inhibition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Schering

Curated by ChEMBL
LigandPNGBDBM18627(Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...)
Affinity DataIC50: 0.0250nMAssay Description:In vitro antagonist potency in transactivation assay in neuroblastoma cells expressing human PR-B progesterone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Schering

Curated by ChEMBL
LigandPNGBDBM50292753(17beta-Hydroxy-11beta-[4-(N-methylpropylamino)-phe...)
Affinity DataIC50: 0.0250nMAssay Description:Antagonist activity at progesterone receptor in human T47D-C124 cells transfected with luciferase gene linked to MMTV promoter assessed as inhibition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Schering

Curated by ChEMBL
LigandPNGBDBM18627(Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...)
Affinity DataIC50: 0.0280nMAssay Description:In vitro antagonist potency in transactivation assay in neuroblastoma cells expressing human PR-A progesterone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Schering

Curated by ChEMBL
LigandPNGBDBM50294705(4-((2-chlorobenzyl)(1-(1-methyl-1H-tetrazol-5-yl)p...)
Affinity DataEC50:  0.0400nMAssay Description:Agonist activity at progesterone receptor in human T47D cells by alkaline phosphatase release based reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Schering

Curated by ChEMBL
LigandPNGBDBM18627(Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...)
Affinity DataIC50: 0.0450nMAssay Description:Antagonist activity at progesterone receptor in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity after 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Schering

Curated by ChEMBL
LigandPNGBDBM50294715(4-((2-chlorobenzyl)(1-(4-methyl-4H-1,2,4-triazol-3...)
Affinity DataEC50:  0.0500nMAssay Description:Agonist activity at progesterone receptor in human T47D cells by alkaline phosphatase release based reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Schering

Curated by ChEMBL
LigandPNGBDBM18627(Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...)
Affinity DataIC50: 0.0500nMAssay Description:Antiprogestagenic activity at progesterone receptor in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Schering

Curated by ChEMBL
LigandPNGBDBM18627(Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...)
Affinity DataIC50: 0.0540nMAssay Description:Antagonist activity at progesterone receptor expressed in human T47D cells assessed as inhibition of promegestone-induced alkaline phosphatase activi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Schering

Curated by ChEMBL
LigandPNGBDBM50292757(17beta-Hydroxy-11beta-[4-(6-hydroxy-N-methylhexyla...)
Affinity DataIC50: 0.0600nMAssay Description:Antagonist activity at progesterone receptor in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity after 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Schering

Curated by ChEMBL
LigandPNGBDBM50292757(17beta-Hydroxy-11beta-[4-(6-hydroxy-N-methylhexyla...)
Affinity DataIC50: 0.0710nMAssay Description:Antagonist activity at progesterone receptor in human T47D-C124 cells transfected with luciferase gene linked to MMTV promoter assessed as inhibition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Schering

Curated by ChEMBL
LigandPNGBDBM50292758(17beta-Hydroxy-11beta-{4-[5-(1,3-dioxol-2-yl)-N-me...)
Affinity DataIC50: 0.0730nMAssay Description:Antagonist activity at progesterone receptor in human T47D-C124 cells transfected with luciferase gene linked to MMTV promoter assessed as inhibition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Schering

Curated by ChEMBL
LigandPNGBDBM50292750(17beta-Hydroxy-11beta-[4-(methylamino)-phenyl]-17a...)
Affinity DataIC50: 0.0730nMAssay Description:Antagonist activity at progesterone receptor in human T47D-C124 cells transfected with luciferase gene linked to MMTV promoter assessed as inhibition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Schering

Curated by ChEMBL
LigandPNGBDBM18627(Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...)
Affinity DataIC50: 0.0730nMAssay Description:Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Schering

Curated by ChEMBL
LigandPNGBDBM50148733(9,21-dichloro-11beta-hydroxy-16alpha-methyl-3,20-d...)
Affinity DataKd:  0.0800nMAssay Description:Dissociation constant for progesterone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Schering

Curated by ChEMBL
LigandPNGBDBM50195153((8S,11R,13S,14S,17S)-17-hydroxy-11-(4-methoxy-phen...)
Affinity DataIC50: 0.0950nMAssay Description:Antagonist activity at progesterone receptor in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity after 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Schering

Curated by ChEMBL
LigandPNGBDBM50304978((S)-methyl 3-((3-chloro-4-cyanophenyl)(2-chloroben...)
Affinity DataEC50:  0.100nMAssay Description:Agonist activity at PR in human T47D cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Schering

Curated by ChEMBL
LigandPNGBDBM50219260(5-(3-cyclopentyl-2-thioxo-2,3-dihydro-1H-benzimida...)
Affinity DataEC50:  0.100nMAssay Description:Agonist activity at progesterone receptor expressed in T47D cells by alkaline phosphatase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Schering

Curated by ChEMBL
LigandPNGBDBM18627(Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of 3 nM [3H]R5020 binding to progesterone receptor of human T47D cell cytosolMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Schering

Curated by ChEMBL
LigandPNGBDBM50067678(17-Acetoxy-6alpha-methylprogesterone | 17alpha-Hyd...)
Affinity DataEC50:  0.100nMAssay Description:Effective concentration on alkaline phosphatase activity in human T47D breast carcinoma cell line.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Schering

Curated by ChEMBL
LigandPNGBDBM8903(CHEMBL103 | (1S,2R,10S,11S,14S,15S)-14-acetyl-2,15...)
Affinity DataEC50:  0.100nMAssay Description:Activation of progesterone receptor in human T47D cells after 20 hrs by PRE-tagged luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Schering

Curated by ChEMBL
LigandPNGBDBM50292756(17beta-Hydroxy-11beta-[4-(3-hydroxy-N-methypropyla...)
Affinity DataIC50: 0.105nMAssay Description:Antagonist activity at progesterone receptor in human T47D-C124 cells transfected with luciferase gene linked to MMTV promoter assessed as inhibition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Schering

Curated by ChEMBL
LigandPNGBDBM50375436(CHEMBL260869)
Affinity DataEC50:  0.120nMAssay Description:Agonist activity at human PRB expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Schering

Curated by ChEMBL
LigandPNGBDBM50067678(17-Acetoxy-6alpha-methylprogesterone | 17alpha-Hyd...)
Affinity DataEC50:  0.120nMAssay Description:Agonistic activity against progesterone receptor in alkaline phosphatase assay using human T47D breast carcinoma cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Schering

Curated by ChEMBL
LigandPNGBDBM50292756(17beta-Hydroxy-11beta-[4-(3-hydroxy-N-methypropyla...)
Affinity DataIC50: 0.120nMAssay Description:Antagonist activity at progesterone receptor in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity after 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Schering

Curated by ChEMBL
LigandPNGBDBM50067678(17-Acetoxy-6alpha-methylprogesterone | 17alpha-Hyd...)
Affinity DataEC50:  0.120nMAssay Description:Effective concentration against PR (progesterone receptor)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Schering

Curated by ChEMBL
LigandPNGBDBM18627(Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...)
Affinity DataIC50: 0.130nMAssay Description:Antagonist activity against progesterone receptor (PR) in an alkaline phosphatase assay in the T47D human breast carcinoma cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Schering

Curated by ChEMBL
LigandPNGBDBM50375439(CHEMBL410304)
Affinity DataIC50: 0.130nMAssay Description:Antagonist activity at human PRB expressed in CHO cells assessed as inhibition of Org 2058 induced-transactivationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Schering

Curated by ChEMBL
LigandPNGBDBM50375821(TANAPROGET)
Affinity DataEC50:  0.150nMAssay Description:Agonist activity at human PR expressed in human T47D cells assessed as stimulation of alkaline phosphataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Schering

Curated by ChEMBL
LigandPNGBDBM50067678(17-Acetoxy-6alpha-methylprogesterone | 17alpha-Hyd...)
Affinity DataEC50:  0.150nMAssay Description:Agonistic activity against human progesterone receptor expressed in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Schering

Curated by ChEMBL
LigandPNGBDBM50067678(17-Acetoxy-6alpha-methylprogesterone | 17alpha-Hyd...)
Affinity DataEC50:  0.150nMAssay Description:Agonist activity was determined against hPR (human progesterone receptor) compared to that of progesterone (100%)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Schering

Curated by ChEMBL
LigandPNGBDBM50375441(CHEMBL260330)
Affinity DataEC50:  0.150nMAssay Description:Agonist activity at human PRB expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Schering

Curated by ChEMBL
LigandPNGBDBM50067678(17-Acetoxy-6alpha-methylprogesterone | 17alpha-Hyd...)
Affinity DataEC50:  0.150nMAssay Description:Effective concentration (EC50) against human progesterone receptor expressed in CV-1 cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Schering

Curated by ChEMBL
LigandPNGBDBM50067678(17-Acetoxy-6alpha-methylprogesterone | 17alpha-Hyd...)
Affinity DataEC50:  0.150nMAssay Description:Agonistic activity was measured for modulation of hPR-B (human progesterone receptor) in co-transfected CV-1 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Schering

Curated by ChEMBL
LigandPNGBDBM50129152((6S,8S,10R,14S,15S)-17-Acetyl-6,10-dimethyl-13-(R)...)
Affinity DataEC50:  0.150nMAssay Description:Effective concentration for agonist activity towards human progesterone receptor (hPR) using the cotransfection assay in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Schering

Curated by ChEMBL
LigandPNGBDBM50067678(17-Acetoxy-6alpha-methylprogesterone | 17alpha-Hyd...)
Affinity DataEC50:  0.150nMAssay Description:Agonistic activity to the human progesterone receptor (hPR)assayed in CV-1 cells in cotransfection assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Schering

Curated by ChEMBL
LigandPNGBDBM50292759(17beta-Hydroxy-11beta-[4-(5-formyl-N-methylpentyla...)
Affinity DataIC50: 0.150nMAssay Description:Antagonist activity at progesterone receptor in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity after 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Schering

Curated by ChEMBL
LigandPNGBDBM50067678(17-Acetoxy-6alpha-methylprogesterone | 17alpha-Hyd...)
Affinity DataEC50:  0.150nMAssay Description:Compound was tested for agonistic activity by cotransfection assay against human Progesterone receptor in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Schering

Curated by ChEMBL
LigandPNGBDBM50292778(17beta-Hydroxy-11beta-{4-[methyl-3-(4-chlorphenyl)...)
Affinity DataIC50: 0.160nMAssay Description:Antagonist activity at progesterone receptor in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity after 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Schering

Curated by ChEMBL
LigandPNGBDBM50292764(17beta-Hydroxy-11beta-[4-(2-methoxycarbonyl-N-meth...)
Affinity DataIC50: 0.160nMAssay Description:Antagonist activity at progesterone receptor in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity after 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Schering

Curated by ChEMBL
LigandPNGBDBM50292750(17beta-Hydroxy-11beta-[4-(methylamino)-phenyl]-17a...)
Affinity DataIC50: 0.170nMAssay Description:Antagonist activity at progesterone receptor in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity after 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Schering

Curated by ChEMBL
LigandPNGBDBM50292788(17beta-Hydroxy-11beta-[4-(1-methyl-9,12-dioxo-1-az...)
Affinity DataIC50: 0.170nMAssay Description:Antagonist activity at progesterone receptor in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity after 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Schering

Curated by ChEMBL
LigandPNGBDBM50292750(17beta-Hydroxy-11beta-[4-(methylamino)-phenyl]-17a...)
Affinity DataIC50: 0.170nMAssay Description:Antiprogestagenic activity at progesterone receptor in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Schering

Curated by ChEMBL
LigandPNGBDBM50292758(17beta-Hydroxy-11beta-{4-[5-(1,3-dioxol-2-yl)-N-me...)
Affinity DataIC50: 0.170nMAssay Description:Antagonist activity at progesterone receptor in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity after 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Schering

Curated by ChEMBL
LigandPNGBDBM18627(Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...)
Affinity DataIC50: 0.180nMAssay Description:Concentration required to give half-maximal inhibition against human Progesterone receptor B isoform in co-transfected CV-1 cell lines.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Schering

Curated by ChEMBL
LigandPNGBDBM18627(Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...)
Affinity DataIC50: 0.180nMAssay Description:Antagonistic activity against human progesterone receptor B (hPR-B) in co-transfected CV-1 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed
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