Compile Data Set for Download or QSAR
Report error Found 102 Enz. Inhib. hit(s) with Target = 'Protein AF-9'
TargetProtein AF-9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50459727(CHEMBL4206834)
Affinity DataKi:  9nMAssay Description:Displacement of N-Flu-DOT1L from MBP-tagged AF9 (unknown origin) (487 to 568 residues) expressed in Escherichia coli BL21(DE3) measured after 3 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProtein AF-9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50606139(CHEMBL5198951)
Affinity DataKi:  9nMAssay Description:Binding affinity to MBP-tagged human recombinant AF9 (487 to 568 residues) incubated for 40 mins by measuring fluorescence polarization by microplate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetProtein AF-9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50606141(CHEMBL5187149)
Affinity DataKi:  9nMAssay Description:Binding affinity to MBP-tagged human recombinant AF9 (487 to 568 residues) incubated for 40 mins by measuring fluorescence polarization by microplate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetProtein AF-9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50459744(CHEMBL4204744)
Affinity DataKi:  10nMAssay Description:Displacement of N-Flu-DOT1L from MBP-tagged AF9 (unknown origin) (487 to 568 residues) expressed in Escherichia coli BL21(DE3) measured after 3 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProtein AF-9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50459737(CHEMBL4211204)
Affinity DataKi:  13nMAssay Description:Displacement of N-Flu-DOT1L from MBP-tagged AF9 (unknown origin) (487 to 568 residues) expressed in Escherichia coli BL21(DE3) measured after 3 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProtein AF-9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50606142(CHEMBL5197715)
Affinity DataKi:  13nMAssay Description:Binding affinity to MBP-tagged human recombinant AF9 (487 to 568 residues) incubated for 40 mins by measuring fluorescence polarization by microplate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetProtein AF-9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50606140(CHEMBL5184570)
Affinity DataKi:  15nMAssay Description:Binding affinity to MBP-tagged human recombinant AF9 (487 to 568 residues) incubated for 40 mins by measuring fluorescence polarization by microplate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetProtein AF-9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50459744(CHEMBL4204744)
Affinity DataKd:  15nMAssay Description:Binding affinity to MBP-tagged AF9 (unknown origin) (487 to 568 residues) expressed in Escherichia coli BL21(DE3) by Bio-layer interferometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProtein AF-9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50606146(CHEMBL5206253)
Affinity DataKi:  17nMAssay Description:Binding affinity to MBP-tagged human recombinant AF9 (487 to 568 residues) incubated for 40 mins by measuring fluorescence polarization by microplate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetProtein AF-9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50606144(CHEMBL5199592)
Affinity DataKi:  19nMAssay Description:Binding affinity to MBP-tagged human recombinant AF9 (487 to 568 residues) incubated for 40 mins by measuring fluorescence polarization by microplate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetProtein AF-9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50459731(CHEMBL4216416)
Affinity DataKi:  20nMAssay Description:Displacement of N-Flu-DOT1L from MBP-tagged AF9 (unknown origin) (487 to 568 residues) expressed in Escherichia coli BL21(DE3) measured after 3 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProtein AF-9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50459738(CHEMBL4209820)
Affinity DataKi:  20nMAssay Description:Displacement of N-Flu-DOT1L from MBP-tagged AF9 (unknown origin) (487 to 568 residues) expressed in Escherichia coli BL21(DE3) measured after 3 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProtein AF-9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50606147(CHEMBL5203898)
Affinity DataKi:  22nMAssay Description:Binding affinity to MBP-tagged human recombinant AF9 (487 to 568 residues) incubated for 40 mins by measuring fluorescence polarization by microplate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetProtein AF-9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50459730(CHEMBL4211714)
Affinity DataKi:  23nMAssay Description:Binding affinity to MBP-tagged human recombinant AF9 (487 to 568 residues) incubated for 40 mins by measuring fluorescence polarization by microplate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetProtein AF-9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50459730(CHEMBL4211714)
Affinity DataKi:  23nMAssay Description:Displacement of N-Flu-DOT1L from MBP-tagged AF9 (unknown origin) (487 to 568 residues) expressed in Escherichia coli BL21(DE3) measured after 3 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProtein AF-9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50606143(CHEMBL5208460)
Affinity DataKi:  23nMAssay Description:Binding affinity to MBP-tagged human recombinant AF9 (487 to 568 residues) incubated for 40 mins by measuring fluorescence polarization by microplate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetProtein AF-9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50606145(CHEMBL5190103)
Affinity DataKi:  29nMAssay Description:Binding affinity to MBP-tagged human recombinant AF9 (487 to 568 residues) incubated for 40 mins by measuring fluorescence polarization by microplate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetProtein AF-9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50606138(CHEMBL5207031)
Affinity DataKi:  32nMAssay Description:Binding affinity to MBP-tagged human recombinant AF9 (487 to 568 residues) incubated for 40 mins by measuring fluorescence polarization by microplate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetProtein AF-9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50459747(CHEMBL4216933)
Affinity DataKi:  50nMAssay Description:Displacement of N-Flu-DOT1L from MBP-tagged AF9 (unknown origin) (487 to 568 residues) expressed in Escherichia coli BL21(DE3) measured after 3 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProtein AF-9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50459726(CHEMBL4211962)
Affinity DataKi:  57nMAssay Description:Displacement of N-Flu-DOT1L from MBP-tagged AF9 (unknown origin) (487 to 568 residues) expressed in Escherichia coli BL21(DE3) measured after 3 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProtein AF-9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50459727(CHEMBL4206834)
Affinity DataIC50: 57nMAssay Description:Displacement of N-Flu-DOT1L from MBP-tagged AF9 (unknown origin) (487 to 568 residues) expressed in Escherichia coli BL21(DE3) measured after 3 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProtein AF-9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50459735(CHEMBL4216170)
Affinity DataKi:  57nMAssay Description:Displacement of N-Flu-DOT1L from MBP-tagged AF9 (unknown origin) (487 to 568 residues) expressed in Escherichia coli BL21(DE3) measured after 3 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProtein AF-9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50625619(CHEMBL4752253)
Affinity DataKd:  76nMAssay Description:Binding affinity to MLLT3 YD domain (unknown origin) assessed as dissociation constant by isothermal calorimetry assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetProtein AF-9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50459737(CHEMBL4211204)
Affinity DataIC50: 82nMAssay Description:Displacement of N-Flu-DOT1L from MBP-tagged AF9 (unknown origin) (487 to 568 residues) expressed in Escherichia coli BL21(DE3) measured after 3 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProtein AF-9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50625619(CHEMBL4752253)
Affinity DataKd:  110nMAssay Description:Binding affinity to MLLT3 YD domain (unknown origin) assessed as dissociation constant by biolayer interferometry assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetProtein AF-9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50625618(CHEMBL5429859)
Affinity DataIC50: 120nMAssay Description:Inhibition of MLLT3 YD domain (unknown origin) assessed as disruption of histone peptide binding using histone peptide as substrate by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetProtein AF-9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50459731(CHEMBL4216416)
Affinity DataIC50: 120nMAssay Description:Displacement of N-Flu-DOT1L from MBP-tagged AF9 (unknown origin) (487 to 568 residues) expressed in Escherichia coli BL21(DE3) measured after 3 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProtein AF-9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50459733(CHEMBL4209508)
Affinity DataKi:  130nMAssay Description:Displacement of N-Flu-DOT1L from MBP-tagged AF9 (unknown origin) (487 to 568 residues) expressed in Escherichia coli BL21(DE3) measured after 3 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProtein AF-9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50459738(CHEMBL4209820)
Affinity DataIC50: 140nMAssay Description:Displacement of N-Flu-DOT1L from MBP-tagged AF9 (unknown origin) (487 to 568 residues) expressed in Escherichia coli BL21(DE3) measured after 3 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProtein AF-9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50459730(CHEMBL4211714)
Affinity DataIC50: 149nMAssay Description:Displacement of N-Flu-DOT1L from MBP-tagged AF9 (unknown origin) (487 to 568 residues) expressed in Escherichia coli BL21(DE3) measured after 3 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProtein AF-9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50459745(CHEMBL4210431)
Affinity DataKi:  160nMAssay Description:Binding affinity to MBP-tagged human recombinant AF9 (487 to 568 residues) incubated for 40 mins by measuring fluorescence polarization by microplate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetProtein AF-9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50625619(CHEMBL4752253)
Affinity DataIC50: 160nMAssay Description:Inhibition of MLLT3 YD domain (unknown origin) assessed as disruption of histone peptide binding using histone peptide as substrate by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetProtein AF-9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50459739(CHEMBL4204942)
Affinity DataKi:  160nMAssay Description:Displacement of N-Flu-DOT1L from MBP-tagged AF9 (unknown origin) (487 to 568 residues) expressed in Escherichia coli BL21(DE3) measured after 3 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProtein AF-9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50606137(CHEMBL5187921)
Affinity DataKi:  160nMAssay Description:Binding affinity to MBP-tagged human recombinant AF9 (487 to 568 residues) incubated for 40 mins by measuring fluorescence polarization by microplate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetProtein AF-9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50459722(CHEMBL4204545)
Affinity DataKi:  160nMAssay Description:Displacement of N-Flu-DOT1L from MBP-tagged AF9 (unknown origin) (487 to 568 residues) expressed in Escherichia coli BL21(DE3) measured after 3 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProtein AF-9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50459745(CHEMBL4210431)
Affinity DataKi:  170nMAssay Description:Displacement of N-Flu-DOT1L from MBP-tagged AF9 (unknown origin) (487 to 568 residues) expressed in Escherichia coli BL21(DE3) measured after 3 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProtein AF-9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50459742(CHEMBL4204647)
Affinity DataKi:  180nMAssay Description:Displacement of N-Flu-DOT1L from MBP-tagged AF9 (unknown origin) (487 to 568 residues) expressed in Escherichia coli BL21(DE3) measured after 3 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProtein AF-9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50459743(CHEMBL4209087)
Affinity DataKi:  190nMAssay Description:Displacement of N-Flu-DOT1L from MBP-tagged AF9 (unknown origin) (487 to 568 residues) expressed in Escherichia coli BL21(DE3) measured after 3 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProtein AF-9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50625617(CHEMBL5421606)
Affinity DataIC50: 200nMAssay Description:Inhibition of MLLT3 YD domain (unknown origin) assessed as disruption of histone peptide binding using histone peptide as substrate by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetProtein AF-9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50459748(CHEMBL4213382)
Affinity DataKi:  250nMAssay Description:Displacement of N-Flu-DOT1L from MBP-tagged AF9 (unknown origin) (487 to 568 residues) expressed in Escherichia coli BL21(DE3) measured after 3 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProtein AF-9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50459746(CHEMBL4212941)
Affinity DataKi:  280nMAssay Description:Displacement of N-Flu-DOT1L from MBP-tagged AF9 (unknown origin) (487 to 568 residues) expressed in Escherichia coli BL21(DE3) measured after 3 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProtein AF-9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50459736(CHEMBL4216206)
Affinity DataKi:  300nMAssay Description:Displacement of N-Flu-DOT1L from MBP-tagged AF9 (unknown origin) (487 to 568 residues) expressed in Escherichia coli BL21(DE3) measured after 3 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProtein AF-9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50459747(CHEMBL4216933)
Affinity DataIC50: 341nMAssay Description:Displacement of N-Flu-DOT1L from MBP-tagged AF9 (unknown origin) (487 to 568 residues) expressed in Escherichia coli BL21(DE3) measured after 3 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProtein AF-9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50459735(CHEMBL4216170)
Affinity DataIC50: 369nMAssay Description:Displacement of N-Flu-DOT1L from MBP-tagged AF9 (unknown origin) (487 to 568 residues) expressed in Escherichia coli BL21(DE3) measured after 3 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProtein AF-9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50576674(CHEMBL4850575)
Affinity DataKd:  370nMAssay Description:Binding affinity to AF9 YEATS domain (1 to 138 residues) (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetProtein AF-9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50459726(CHEMBL4211962)
Affinity DataIC50: 372nMAssay Description:Displacement of N-Flu-DOT1L from MBP-tagged AF9 (unknown origin) (487 to 568 residues) expressed in Escherichia coli BL21(DE3) measured after 3 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProtein AF-9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50459729(CHEMBL4217882)
Affinity DataKi:  410nMAssay Description:Displacement of N-Flu-DOT1L from MBP-tagged AF9 (unknown origin) (487 to 568 residues) expressed in Escherichia coli BL21(DE3) measured after 3 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProtein AF-9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50576674(CHEMBL4850575)
Affinity DataIC50: 410nMAssay Description:Inhibition of AF9 YEATS domain (1 to 138 residues) (unknown origin) assessed as inhibition of probe-1 induced AF9 YEATS domain labelling incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetProtein AF-9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50625616(CHEMBL5398308)
Affinity DataIC50: 500nMAssay Description:Inhibition of MLLT3 YD domain (unknown origin) assessed as disruption of histone peptide binding using histone peptide as substrate by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetProtein AF-9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50625612(CHEMBL5416331)
Affinity DataIC50: 500nMAssay Description:Inhibition of MLLT3 YD domain (unknown origin) assessed as disruption of histone peptide binding using histone peptide as substrate by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
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