Compile Data Set for Download or QSAR
Report error Found 1876 Enz. Inhib. hit(s) with Target = 'Proteinase-activated receptor 4'
TargetProteinase-activated receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM175970(US9688695, 3 | US10047103, 3 | US9605024, Example ...)
Affinity DataIC50: 0.00400nMAssay Description:Antagonist activity at PAR4 (unknown origin) assessed as inhibition of activating peptide-induced receptor activationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2018
Entry Details Article
PubMed
TargetProteinase-activated receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM175970(US9688695, 3 | US10047103, 3 | US9605024, Example ...)
Affinity DataIC50: 0.0230nMAssay Description:Antagonist activity at PAR4 (unknown origin) assessed as inhibition of gamma-thrombin-induced receptor activationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2018
Entry Details Article
PubMed
TargetProteinase-activated receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM176061(US9688695, 94 | US10047103, 94)
Affinity DataKd:  0.0700nMAssay Description:Binding affinity to PAR4 (unknown origin) assessed as association constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetProteinase-activated receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM176003(US9688695, 36 | US10047103, 36)
Affinity DataKd:  0.0860nMAssay Description:Binding affinity to PAR4 (unknown origin) assessed as association constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetProteinase-activated receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM176061(US9688695, 94 | US10047103, 94)
Affinity DataKd:  0.0980nMAssay Description:Binding affinity to PAR4 (unknown origin) assessed as saturation bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetProteinase-activated receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM176003(US9688695, 36 | US10047103, 36)
Affinity DataKd:  0.100nMAssay Description:Binding affinity to PAR4 (unknown origin) assessed as saturation bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetProteinase-activated receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM176195(US9688695, 228 | US10047103, 228)
Affinity DataEC50:  0.180nMT: 2°CAssay Description:The activity of the PAR4 antagonists of the present invention were tested in PAR4 expressing cells by monitoring H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2018
Entry Details
US Patent

TargetProteinase-activated receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM176195(US9688695, 228 | US10047103, 228)
Affinity DataEC50:  0.180nMT: 2°CAssay Description:Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetProteinase-activated receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM176023(US9688695, 56 | US10047103, 56)
Affinity DataIC50: 0.200nMAssay Description:Antagonist activity at full length human PAR4 expressed in HEK293 cells assessed as reduction in H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-Lys-Asn-Gly-NH2 i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetProteinase-activated receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM176017(US9688695, 50 | US10047103, 50)
Affinity DataEC50:  0.210nMT: 2°CAssay Description:The activity of the PAR4 antagonists of the present invention were tested in PAR4 expressing cells by monitoring H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2018
Entry Details
US Patent

TargetProteinase-activated receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM176017(US9688695, 50 | US10047103, 50)
Affinity DataEC50:  0.210nMT: 2°CAssay Description:Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetProteinase-activated receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM176036(US9688695, 69 | US10047103, 69)
Affinity DataEC50:  0.230nMT: 2°CAssay Description:The activity of the PAR4 antagonists of the present invention were tested in PAR4 expressing cells by monitoring H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2018
Entry Details
US Patent

TargetProteinase-activated receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM286492(2-Methoxy-6-(6-methoxy-4-((6-(4-methoxytetrahydro-...)
Affinity DataIC50: 0.230nMT: 2°CAssay Description:The activity of the PAR4 antagonists of the present invention were tested in PAR4 expressing cells by monitoring H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent

TargetProteinase-activated receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM286477(4-(6-(((6-Methoxy-2-(2-methoxyimidazo[2,1-b][1,3,4...)
Affinity DataIC50: 0.230nMT: 2°CAssay Description:The activity of the PAR4 antagonists of the present invention were tested in PAR4 expressing cells by monitoring H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent

TargetProteinase-activated receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM176036(US9688695, 69 | US10047103, 69)
Affinity DataEC50:  0.230nMT: 2°CAssay Description:Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetProteinase-activated receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM176023(US9688695, 56 | US10047103, 56)
Affinity DataEC50:  0.240nMT: 2°CAssay Description:Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetProteinase-activated receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM176023(US9688695, 56 | US10047103, 56)
Affinity DataEC50:  0.240nMT: 2°CAssay Description:The activity of the PAR4 antagonists of the present invention were tested in PAR4 expressing cells by monitoring H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2018
Entry Details
US Patent

TargetProteinase-activated receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM176067(US9688695, 100 | US10047103, 100)
Affinity DataEC50:  0.25nMT: 2°CAssay Description:The activity of the PAR4 antagonists of the present invention were tested in PAR4 expressing cells by monitoring H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2018
Entry Details
US Patent

TargetProteinase-activated receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM176067(US9688695, 100 | US10047103, 100)
Affinity DataEC50:  0.25nMT: 2°CAssay Description:Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetProteinase-activated receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM176111(US9688695, 144 | US10047103, 144)
Affinity DataEC50:  0.260nMT: 2°CAssay Description:Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetProteinase-activated receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM176018(US9688695, 51 | US10047103, 51)
Affinity DataEC50:  0.260nMT: 2°CAssay Description:The activity of the PAR4 antagonists of the present invention were tested in PAR4 expressing cells by monitoring H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2018
Entry Details
US Patent

TargetProteinase-activated receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM176111(US9688695, 144 | US10047103, 144)
Affinity DataEC50:  0.260nMT: 2°CAssay Description:The activity of the PAR4 antagonists of the present invention were tested in PAR4 expressing cells by monitoring H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2018
Entry Details
US Patent

TargetProteinase-activated receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM176007(US9688695, 40 | US10047103, 40)
Affinity DataEC50:  0.260nMT: 2°CAssay Description:Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetProteinase-activated receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM176039(US9688695, 72 | US10047103, 72)
Affinity DataEC50:  0.260nMT: 2°CAssay Description:Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetProteinase-activated receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM176134(US9688695, 167 | US10047103, 167)
Affinity DataEC50:  0.260nMT: 2°CAssay Description:Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetProteinase-activated receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM176007(US9688695, 40 | US10047103, 40)
Affinity DataEC50:  0.260nMT: 2°CAssay Description:The activity of the PAR4 antagonists of the present invention were tested in PAR4 expressing cells by monitoring H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2018
Entry Details
US Patent

TargetProteinase-activated receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM176039(US9688695, 72 | US10047103, 72)
Affinity DataEC50:  0.260nMT: 2°CAssay Description:The activity of the PAR4 antagonists of the present invention were tested in PAR4 expressing cells by monitoring H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2018
Entry Details
US Patent

TargetProteinase-activated receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM176018(US9688695, 51 | US10047103, 51)
Affinity DataEC50:  0.260nMT: 2°CAssay Description:Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetProteinase-activated receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM176134(US9688695, 167 | US10047103, 167)
Affinity DataEC50:  0.260nMT: 2°CAssay Description:The activity of the PAR4 antagonists of the present invention were tested in PAR4 expressing cells by monitoring H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2018
Entry Details
US Patent

TargetProteinase-activated receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM176259(US9688695, 292 | US10047103, 292)
Affinity DataEC50:  0.270nMT: 2°CAssay Description:The activity of the PAR4 antagonists of the present invention were tested in PAR4 expressing cells by monitoring H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2018
Entry Details
US Patent

TargetProteinase-activated receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM176058(US9688695, 91 | US10047103, 91)
Affinity DataEC50:  0.270nMT: 2°CAssay Description:Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetProteinase-activated receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM176138(US9688695, 171 | US10047103, 171)
Affinity DataEC50:  0.270nMT: 2°CAssay Description:Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetProteinase-activated receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM176088(US9688695, 121 | US10047103, 121)
Affinity DataEC50:  0.270nMT: 2°CAssay Description:Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetProteinase-activated receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM176058(US9688695, 91 | US10047103, 91)
Affinity DataEC50:  0.270nMT: 2°CAssay Description:The activity of the PAR4 antagonists of the present invention were tested in PAR4 expressing cells by monitoring H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2018
Entry Details
US Patent

TargetProteinase-activated receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM176138(US9688695, 171 | US10047103, 171)
Affinity DataEC50:  0.270nMT: 2°CAssay Description:The activity of the PAR4 antagonists of the present invention were tested in PAR4 expressing cells by monitoring H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2018
Entry Details
US Patent

TargetProteinase-activated receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM176088(US9688695, 121 | US10047103, 121)
Affinity DataEC50:  0.270nMT: 2°CAssay Description:The activity of the PAR4 antagonists of the present invention were tested in PAR4 expressing cells by monitoring H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2018
Entry Details
US Patent

TargetProteinase-activated receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM176259(US9688695, 292 | US10047103, 292)
Affinity DataEC50:  0.270nMT: 2°CAssay Description:Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetProteinase-activated receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM176135(US9688695, 168 | US10047103, 168)
Affinity DataEC50:  0.280nMT: 2°CAssay Description:Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetProteinase-activated receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM176135(US9688695, 168 | US10047103, 168)
Affinity DataEC50:  0.280nMT: 2°CAssay Description:The activity of the PAR4 antagonists of the present invention were tested in PAR4 expressing cells by monitoring H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2018
Entry Details
US Patent

TargetProteinase-activated receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM176179(US9688695, 212 | US10047103, 212)
Affinity DataEC50:  0.290nMT: 2°CAssay Description:The activity of the PAR4 antagonists of the present invention were tested in PAR4 expressing cells by monitoring H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2018
Entry Details
US Patent

TargetProteinase-activated receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM176091(US9688695, 124 | US10047103, 124)
Affinity DataEC50:  0.290nMT: 2°CAssay Description:Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetProteinase-activated receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM176091(US9688695, 124 | US10047103, 124)
Affinity DataEC50:  0.290nMT: 2°CAssay Description:The activity of the PAR4 antagonists of the present invention were tested in PAR4 expressing cells by monitoring H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2018
Entry Details
US Patent

TargetProteinase-activated receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM286479(US9518064, Example 98)
Affinity DataIC50: 0.290nMT: 2°CAssay Description:The activity of the PAR4 antagonists of the present invention were tested in PAR4 expressing cells by monitoring H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent

TargetProteinase-activated receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM176179(US9688695, 212 | US10047103, 212)
Affinity DataEC50:  0.290nMT: 2°CAssay Description:Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetProteinase-activated receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM176149(US9688695, 182 | US10047103, 182)
Affinity DataEC50:  0.300nMT: 2°CAssay Description:The activity of the PAR4 antagonists of the present invention were tested in PAR4 expressing cells by monitoring H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2018
Entry Details
US Patent

TargetProteinase-activated receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM176053(US9688695, 86 | US10047103, 86)
Affinity DataIC50: 0.300nMAssay Description:Antagonist activity at full length human PAR4 expressed in HEK293 cells assessed as reduction in H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-Lys-Asn-Gly-NH2 i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetProteinase-activated receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM176039(US9688695, 72 | US10047103, 72)
Affinity DataIC50: 0.300nMAssay Description:Antagonist activity at full length human PAR4 expressed in HEK293 cells assessed as reduction in H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-Lys-Asn-Gly-NH2 i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetProteinase-activated receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM176053(US9688695, 86 | US10047103, 86)
Affinity DataEC50:  0.300nMT: 2°CAssay Description:Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

TargetProteinase-activated receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM176082(US9688695, 115 | US10047103, 115)
Affinity DataIC50: 0.300nMAssay Description:Antagonist activity at full length human PAR4 expressed in HEK293 cells assessed as reduction in H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-Lys-Asn-Gly-NH2 i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetProteinase-activated receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM176149(US9688695, 182 | US10047103, 182)
Affinity DataEC50:  0.300nMT: 2°CAssay Description:Briefly, HEK293 EBNA PAR4 clone 20664.1J cells were plated 24 hrs. prior to experiment in 384 well, Poly-D-Lysine coated, black, clear bottom plates ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent

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