Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with Target = 'Ribosomal protein S6 kinase beta-2'
TargetRibosomal protein S6 kinase beta-2(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 0.726nMAssay Description:Inhibition of human p70S6Kb using KKRNRTLTK as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-2(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM130909(US8822500, Stauro- sporine | US9920060, Staurospor...)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human p70S6Kb using KKRNRTLTK as substrate preincubated for 20 mins followed by [gamma-33P]-ATP addition and measured after 120 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetRibosomal protein S6 kinase beta-2(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human p70S6Kb using KKRNRTLTK as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-2(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50644192(CHEMBL5570033)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of human wild type S6K2 using RBER-CHKtide as substrate in presence of ATP by hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetRibosomal protein S6 kinase beta-2(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50644193(CHEMBL5571683)
Affinity DataIC50: 18nMAssay Description:Inhibition of human wild type S6K2 using RBER-CHKtide as substrate in presence of ATP by hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetRibosomal protein S6 kinase beta-2(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50168247(2,3-Di-thiophen-2-yl-benzo[g]quinoxaline-7-carboxy...)
Affinity DataIC50: 40nMAssay Description:In vitro inhibition of SR protein kinase 1 by compound dissolved in 100% DMSO using 5''-[gamma-33P]-triphosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-2(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50168248({5-[3-(4-Carboxymethyl-thiophen-2-yl)-benzo[g]quin...)
Affinity DataIC50: 640nMAssay Description:In vitro inhibition of SR protein kinase 1 by compound dissolved in 100% DMSO using 5''-[gamma-33P]-triphosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-2(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50168244(4-(5-{3-[5-(3-Carboxy-propyl)-thiophen-2-yl]-benzo...)
Affinity DataIC50: 820nMAssay Description:In vitro inhibition of SR protein kinase 1 by compound dissolved in 100% DMSO using 5''-[gamma-33P]-triphosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-2(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50168242(3-(5-{3-[5-(2-Carboxy-ethyl)-thiophen-2-yl]-benzo[...)
Affinity DataIC50: 870nMAssay Description:In vitro inhibition of SR protein kinase 1 by compound dissolved in 100% DMSO using 5''-[gamma-33P]-triphosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-2(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50168241(6,7-Di-thiophen-2-yl-2,3-dihydro-1,4-dioxa-5,8-dia...)
Affinity DataIC50: 950nMAssay Description:In vitro inhibition of SR protein kinase 1 by compound dissolved in 100% DMSO using 5''-[gamma-33P]-triphosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-2(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50168239(7,8-Dimethoxy-2,3-di-thiophen-2-yl-pyrazino[2,3-b]...)
Affinity DataIC50: 1.14E+3nMAssay Description:In vitro inhibition of SR protein kinase 1 by compound dissolved in 100% DMSO using 5''-[gamma-33P]-triphosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-2(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50168236({5-[3-(5-Carboxymethyl-thiophen-2-yl)-benzo[g]quin...)
Affinity DataIC50: 1.28E+3nMAssay Description:In vitro inhibition of SR protein kinase 1 by compound dissolved in 100% DMSO using 5''-[gamma-33P]-triphosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-2(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50168235(2,3-Di-thiophen-2-yl-benzo[g]quinoxaline | CHEMBL3...)
Affinity DataIC50: 1.36E+3nMAssay Description:In vitro inhibition of SR protein kinase 1 by compound dissolved in 100% DMSO using 5''-[gamma-33P]-triphosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-2(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50583520(CHEMBL5094006)
Affinity DataIC50: 1.65E+3nMAssay Description:Inhibition of human recombinant P70S6Kbeta expressed in Sf9 insect cells using [KKRNRTLTK] as substrate in presence of [33P]-ATP by radiometric hotsp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-2(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50168243(3-(5-{3-[5-(2-Methoxycarbonyl-ethyl)-thiophen-2-yl...)
Affinity DataIC50: 6.13E+3nMAssay Description:In vitro inhibition of SR protein kinase 1 by compound dissolved in 100% DMSO using 5''-[gamma-33P]-triphosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-2(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50168246(2,3-Di-thiophen-2-yl-quinoxaline-6,7-diol | CHEMBL...)
Affinity DataIC50: 9.61E+3nMAssay Description:In vitro inhibition of SR protein kinase 1 by compound dissolved in 100% DMSO using 5''-[gamma-33P]-triphosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-2(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50168249(5-[3-(5-carboxythien-2-yl)benzo[g]quinoxalin-2-yl]...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibition of SR protein kinase 1 by compound dissolved in 100% DMSO using 5''-[gamma-33P]-triphosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-2(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50135286(CHEMBL3745885)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human RPS6KB2 using [KKRNRTLTK] as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2017
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-2(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50168250({5-[3-(4-Methoxycarbonylmethyl-thiophen-2-yl)-benz...)
Affinity DataIC50: 1.18E+4nMAssay Description:In vitro inhibition of SR protein kinase 1 by compound dissolved in 100% DMSO using 5''-[gamma-33P]-triphosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-2(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50168238(6,7-Dimethoxy-2,3-di-thiophen-2-yl-quinoxaline | C...)
Affinity DataIC50: 1.63E+4nMAssay Description:In vitro inhibition of SR protein kinase 1 by compound dissolved in 100% DMSO using 5''-[gamma-33P]-triphosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-2(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50168237(6,7-Di-thiophen-2-yl-2,3-dihydro-1,4-dioxa-5,8-dia...)
Affinity DataIC50: 2.34E+4nMAssay Description:In vitro inhibition of SR protein kinase 1 by compound dissolved in 100% DMSO using 5''-[gamma-33P]-triphosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-2(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50168240(6,7-Di-thiophen-2-yl-[1,3]dioxolo[4,5-g]quinoxalin...)
Affinity DataIC50: 2.85E+4nMAssay Description:In vitro inhibition of SR protein kinase 1 by compound dissolved in 100% DMSO using 5''-[gamma-33P]-triphosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-2(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50337134(US9266890, IV-6 | Scaffold, B46 | CHEMBL1673046 | ...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of P70S6KB in human HeLa cells lysate pre incubated for 15 mins followed by ATP acyl phosphate probe addition and measured after 10 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed