Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with Target = 'Store-operated calcium entry-associated regulatory factor'
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  147nMAssay Description:Binding affinity to human SARAF incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM387313(US10292981, Example 15 | N-(5′- (5,5-dimeth...)
Affinity DataIC50: 1.00E+3nMAssay Description:Jurkat E6.1 cells were seeded at a density of 1-2×105 cells per well in calcium-4 dye prepared in calcium free HBSS (Sigma, USA). Test compounds from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent

LigandPNGBDBM387280(US10292981, Example 176 | N-(2,6- Difluorophenyl)-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Jurkat E6.1 cells were seeded at a density of 1-2×105 cells per well in calcium-4 dye prepared in calcium free HBSS (Sigma, USA). Test compounds from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent

LigandPNGBDBM387277(US10292981, Example 160 | N-(2,6- Difluorophenyl)-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Jurkat E6.1 cells were seeded at a density of 1-2×105 cells per well in calcium-4 dye prepared in calcium free HBSS (Sigma, USA). Test compounds from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent

LigandPNGBDBM387273(US10292981, Example 135)
Affinity DataIC50: 1.00E+3nMAssay Description:Jurkat E6.1 cells were seeded at a density of 1-2×105 cells per well in calcium-4 dye prepared in calcium free HBSS (Sigma, USA). Test compounds from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent

LigandPNGBDBM387314(US10292981, Example 41 | 2- Chloro-6-fluoro-N- (2&...)
Affinity DataIC50: 1.00E+3nMAssay Description:Jurkat E6.1 cells were seeded at a density of 1-2×105 cells per well in calcium-4 dye prepared in calcium free HBSS (Sigma, USA). Test compounds from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent