Compile Data Set for Download or QSAR
Report error Found 73 Enz. Inhib. hit(s) with Target = 'Vasoactive intestinal polypeptide receptor 1'
LigandPNGBDBM50435130(CHEMBL1893324)
Affinity DataEC50:  0.0200nMAssay Description:Agonist activity at VPAC1 in human SH-SY5Y cells assessed as cAMP accumulation incubated for 60 mins by Eu-cAMP tracer based LANCE ultra cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50606527(CHEMBL5220770)
Affinity DataEC50:  0.0300nMAssay Description:Agonist activity at VPAC1 in human SH-SY5Y cells assessed as cAMP accumulation incubated for 60 mins by Eu-cAMP tracer based LANCE ultra cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50250019(PACAP | PACAP-38 | CHEMBL524658 | PACAP(1-38) | PA...)
Affinity DataIC50: 0.0400nMAssay Description:Displacement of [125I]PACAP1-27 from human recombinant PAC1 receptor expressed in CHO cells measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2018
Entry Details Article
PubMed
LigandPNGBDBM50250019(PACAP | PACAP-38 | CHEMBL524658 | PACAP(1-38) | PA...)
Affinity DataIC50: 0.0500nMAssay Description:Binding affinity to human VPAC1 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50435130(CHEMBL1893324)
Affinity DataKi:  0.0670nMAssay Description:Binding affinity to human VPAC1 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50435130(CHEMBL1893324)
Affinity DataIC50: 0.110nMAssay Description:Displacement of [125I]VIP from human recombinant VIP1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2017
Entry Details Article
PubMed
LigandPNGBDBM50208990(CHEMBL3884667)
Affinity DataIC50: 0.110nMAssay Description:Displacement of [125I]VIP from human recombinant VPAC1 receptor expressed in CHO cells measured after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2018
Entry Details Article
PubMed
LigandPNGBDBM50435130(CHEMBL1893324)
Affinity DataIC50: 0.120nMAssay Description:Binding affinity to human VPAC1 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50435130(CHEMBL1893324)
Affinity DataIC50: 0.120nMAssay Description:Binding affinity to human VPAC1 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM81828(CAS_37221-79-7 | VIP(4-28) | Vasoactive intestinal...)
Affinity DataKi:  0.200nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
LigandPNGBDBM392076(US10301272, Example 7/9)
Affinity DataIC50: 0.470nMAssay Description:Displacement of [125I]VIP from human recombinant VPAC1 receptor after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2020
Entry Details Article
PubMed
LigandPNGBDBM50200209(CHEMBL219499)
Affinity DataEC50:  0.600nMAssay Description:Activity at human VPAC1 receptor in CHO cells by measuring cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
LigandPNGBDBM81828(CAS_37221-79-7 | VIP(4-28) | Vasoactive intestinal...)
Affinity DataKi:  1.60nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
LigandPNGBDBM81828(CAS_37221-79-7 | VIP(4-28) | Vasoactive intestinal...)
Affinity DataKi:  1.70nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
LigandPNGBDBM86051(NSC_0 | CAS_0 | [Lys15, Arg16, Leu27]VIP(1-7)GRF(8...)
Affinity DataKi:  1.70nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50250018(PACAP27 | CHEMBL524852)
Affinity DataIC50: 5.90nMAssay Description:Displacement of Ac-[125I]-PACAP27 from recombinant human VPAC1 expressed in CHO cells after 90 mins by gamma counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
LigandPNGBDBM86051(NSC_0 | CAS_0 | [Lys15, Arg16, Leu27]VIP(1-7)GRF(8...)
Affinity DataKi:  7.70nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
LigandPNGBDBM86051(NSC_0 | CAS_0 | [Lys15, Arg16, Leu27]VIP(1-7)GRF(8...)
Affinity DataKi:  8.90nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50498951(CHEMBL3736134)
Affinity DataIC50: 9nMAssay Description:Displacement of Ac-[125I]-PACAP27 from recombinant human VPAC1 expressed in CHO cells after 90 mins by gamma counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
LigandPNGBDBM50498951(CHEMBL3736134)
Affinity DataIC50: 9.30nMAssay Description:Displacement of Ac-[125I]-PACAP27 from recombinant human VPAC1 expressed in CHO cells after 90 mins by gamma counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
LigandPNGBDBM50498950(CHEMBL3736230)
Affinity DataIC50: 11nMAssay Description:Displacement of Ac-[125I]-PACAP27 from recombinant human VPAC1 expressed in CHO cells after 90 mins by gamma counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
LigandPNGBDBM50200209(CHEMBL219499)
Affinity DataIC50: 12nMAssay Description:Displacement of [125I]PACAP27 from human VPAC1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
LigandPNGBDBM50498950(CHEMBL3736230)
Affinity DataIC50: 12nMAssay Description:Displacement of Ac-[125I]-PACAP27 from recombinant human VPAC1 expressed in CHO cells after 90 mins by gamma counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
LigandPNGBDBM50250074([Bip6]PACAP27 | CHEMBL507480)
Affinity DataIC50: 14nMAssay Description:Displacement of Ac-[125I]-PACAP27 from recombinant human VPAC1 expressed in CHO cells after 90 mins by gamma counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetVasoactive intestinal polypeptide receptor 1(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50365986(CHEMBL1956427)
Affinity DataIC50: 81nMAssay Description:Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetVasoactive intestinal polypeptide receptor 1(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50365985(CHEMBL1956426)
Affinity DataIC50: 100nMAssay Description:Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50606528(CHEMBL5219662)
Affinity DataIC50: 118nMAssay Description:Antagonist activity at VPAC1 in human SH-SY5Y cells assessed as inhibition of PACAP38-induced cAMP accumulation pre-incubated for 30 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetVasoactive intestinal polypeptide receptor 1(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50366026(CHEMBL1956425)
Affinity DataIC50: 120nMAssay Description:Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetVasoactive intestinal polypeptide receptor 1(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50366024(CHEMBL1956413)
Affinity DataIC50: 170nMAssay Description:Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetVasoactive intestinal polypeptide receptor 1(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50366025(CHEMBL1956424)
Affinity DataIC50: 180nMAssay Description:Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetVasoactive intestinal polypeptide receptor 1(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50366023(CHEMBL1956412)
Affinity DataIC50: 200nMAssay Description:Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetVasoactive intestinal polypeptide receptor 1(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50366022(CHEMBL1956423)
Affinity DataIC50: 210nMAssay Description:Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetVasoactive intestinal polypeptide receptor 1(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50366021(CHEMBL1956422)
Affinity DataIC50: 240nMAssay Description:Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetVasoactive intestinal polypeptide receptor 1(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50366020(CHEMBL1956421)
Affinity DataIC50: 290nMAssay Description:Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetVasoactive intestinal polypeptide receptor 1(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50365996(CHEMBL1956433)
Affinity DataIC50: 290nMAssay Description:Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetVasoactive intestinal polypeptide receptor 1(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50366019(CHEMBL1956420)
Affinity DataIC50: 300nMAssay Description:Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetVasoactive intestinal polypeptide receptor 1(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50366018(CHEMBL1956419)
Affinity DataIC50: 310nMAssay Description:Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetVasoactive intestinal polypeptide receptor 1(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50366017(CHEMBL1956418)
Affinity DataIC50: 390nMAssay Description:Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetVasoactive intestinal polypeptide receptor 1(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50366001(CHEMBL1956438)
Affinity DataIC50: 410nMAssay Description:Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetVasoactive intestinal polypeptide receptor 1(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50365994(CHEMBL396627)
Affinity DataIC50: 470nMAssay Description:Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetVasoactive intestinal polypeptide receptor 1(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50365993(CHEMBL1956432)
Affinity DataIC50: 470nMAssay Description:Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetVasoactive intestinal polypeptide receptor 1(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50365999(CHEMBL1956436)
Affinity DataIC50: 480nMAssay Description:Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetVasoactive intestinal polypeptide receptor 1(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50366000(CHEMBL1956437)
Affinity DataIC50: 610nMAssay Description:Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetVasoactive intestinal polypeptide receptor 1(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50366016(CHEMBL1956417)
Affinity DataIC50: 680nMAssay Description:Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetVasoactive intestinal polypeptide receptor 1(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50366015(CHEMBL1956416)
Affinity DataIC50: 740nMAssay Description:Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetVasoactive intestinal polypeptide receptor 1(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50365998(CHEMBL1956435)
Affinity DataIC50: 750nMAssay Description:Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetVasoactive intestinal polypeptide receptor 1(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50366014(CHEMBL1956415)
Affinity DataIC50: 820nMAssay Description:Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandPNGBDBM86050(Ac-L-His-L-Ser-L-Asp-L-Ala-L-Val-L-Phe-L-Thr-L-Glu...)
Affinity DataKi:  1.02E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
TargetVasoactive intestinal polypeptide receptor 1(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50366002(CHEMBL1956439)
Affinity DataIC50: 1.20E+3nMAssay Description:Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandPNGBDBM86050(Ac-L-His-L-Ser-L-Asp-L-Ala-L-Val-L-Phe-L-Thr-L-Glu...)
Affinity DataKi:  1.20E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
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