Report error Found 1283 Enz. Inhib. hit(s) with Target = 'Vasopressin V1b receptor'
TargetVasopressin V1b receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataEC50: 0.00350nMAssay Description:Agonist activity at recombinant human V1b receptor expressed in HEK293 cells assessed as increase in intracellular calcium level measured at 3 secs i...More data for this Ligand-Target Pair
TargetVasopressin V1b receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 0.0300nMAssay Description:Displacement of [3H]AVP from human vasopressin V1b receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
TargetVasopressin V1b receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 0.0300nMAssay Description:Displacement of [3H]AVP from human vasopressin V1b receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
TargetVasopressin V1b receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 0.0400nMAssay Description:Displacement of [3H]AVP from human vasopressin V1b receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.0400nMAssay Description:Displacement of [3H]AVP from rat vasopressin V1b receptor expressed in At-T20 cellsMore data for this Ligand-Target Pair
TargetVasopressin V1b receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 0.0800nMAssay Description:Displacement of [3H]AVP from human vasopressin V1b receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.130nMAssay Description:Displacement of [3H]AVP from rat vasopressin V1b receptor expressed in At-T20 cellsMore data for this Ligand-Target Pair
TargetVasopressin V1b receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataIC50: 0.160nMpH: 7.4 T: 2°CAssay Description:Human V1b receptor was transiently expressed in 293FT cells (Invitrogen). The cells were collected and then homogenated in a 15 mmol/L tris-hydrochlo...More data for this Ligand-Target Pair
TargetVasopressin V1b receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataIC50: 0.160nMpH: 7.4 T: 2°CAssay Description:Human V1b receptor was transiently expressed in 293FT cells (Invitrogen). The cells were collected and then homogenated in a 15 mmol/L tris-hydrochlo...More data for this Ligand-Target Pair
Affinity DataKi: 0.160nMAssay Description:Displacement of [3H]AVP from rat vasopressin V1b receptor expressed in At-T20 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.190nMAssay Description:Displacement of [3H]AVP from rat vasopressin V1b receptor expressed in At-T20 cellsMore data for this Ligand-Target Pair
TargetVasopressin V1b receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataEC50: 0.200nMAssay Description:Agonist activity at human V1B receptor expressed in HEK293 cells assessed as intracellular calcium level measured at 3 secs interval for 5 mins by fu...More data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]AVP from rat vasopressin V1b receptor expressed in At-T20 cellsMore data for this Ligand-Target Pair
TargetVasopressin V1b receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 0.230nMAssay Description:Binding affinity against human vasopressin V1b receptor was determined by using plasma membranes from CHO cells stably transfected with VP/OT recepto...More data for this Ligand-Target Pair
TargetVasopressin V1b receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataEC50: 0.240nMAssay Description:Agonist activity at recombinant human V1b receptor expressed in HEK293 cells assessed as increase in intracellular calcium level measured at 3 secs i...More data for this Ligand-Target Pair
Affinity DataKi: 0.25nMAssay Description:Displacement of [3H]AVP from rat vasopressin V1b receptor expressed in At-T20 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.25nMAssay Description:Displacement of [3H]AVP from rat vasopressin V1b receptor expressed in At-T20 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.260nMAssay Description:Displacement of [3H]AVP from rat vasopressin V1b receptor expressed in At-T20 cellsMore data for this Ligand-Target Pair
TargetVasopressin V1b receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 0.260nMAssay Description:Displacement of [3H]AVP from human vasopressin V1b receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
TargetVasopressin V1b receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 0.290nMAssay Description:Binding affinity against human vasopressin V1b receptor was determined by using plasma membranes from CHO cells stably transfected with VP/OT recepto...More data for this Ligand-Target Pair
TargetVasopressin V1b receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 0.370nMAssay Description:Binding affinity against human vasopressin V1b receptor was determined by using plasma membranes from CHO cells stably transfected with VP/OT recepto...More data for this Ligand-Target Pair
Affinity DataKi: 0.380nMAssay Description:Displacement of [3H]AVP from rat vasopressin V1b receptor expressed in At-T20 cellsMore data for this Ligand-Target Pair
TargetVasopressin V1b receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 0.420nMAssay Description:Binding affinity against human vasopressin V1b receptor was determined by using plasma membranes from CHO cells stably transfected with VP/OT recepto...More data for this Ligand-Target Pair
TargetVasopressin V1b receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataIC50: 0.430nMpH: 7.4 T: 2°CAssay Description:Human V1b receptor was transiently expressed in 293FT cells (Invitrogen). The cells were collected and then homogenated in a 15 mmol/L tris-hydrochlo...More data for this Ligand-Target Pair
TargetVasopressin V1b receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataIC50: 0.430nMpH: 7.4 T: 2°CAssay Description:Human V1b receptor was transiently expressed in 293FT cells (Invitrogen). The cells were collected and then homogenated in a 15 mmol/L tris-hydrochlo...More data for this Ligand-Target Pair
TargetVasopressin V1b receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 0.430nMAssay Description:Binding affinity against human vasopressin V1b receptor was determined by using plasma membranes from CHO cells stably transfected with VP/OT recepto...More data for this Ligand-Target Pair
Affinity DataKi: 0.450nMAssay Description:Displacement of [3H]AVP from rat vasopressin V1b receptor expressed in At-T20 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.450nMAssay Description:Displacement of [3H]AVP from rat vasopressin V1b receptor expressed in At-T20 cellsMore data for this Ligand-Target Pair
TargetVasopressin V1b receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 0.490nMAssay Description:Binding affinity against human vasopressin V1b receptor was determined by using plasma membranes from CHO cells stably transfected with VP/OT recepto...More data for this Ligand-Target Pair
TargetVasopressin V1b receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataIC50: 0.490nMpH: 7.4 T: 2°CAssay Description:Human V1b receptor was transiently expressed in 293FT cells (Invitrogen). The cells were collected and then homogenated in a 15 mmol/L tris-hydrochlo...More data for this Ligand-Target Pair
TargetVasopressin V1b receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataIC50: 0.490nMpH: 7.4 T: 2°CAssay Description:Human V1b receptor was transiently expressed in 293FT cells (Invitrogen). The cells were collected and then homogenated in a 15 mmol/L tris-hydrochlo...More data for this Ligand-Target Pair
TargetVasopressin V1b receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 0.490nMAssay Description:Displacement of [3H]-AVP from human vasopressin V1b receptor expressed in CHO cells after 30 minsMore data for this Ligand-Target Pair
TargetVasopressin V1b receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataEC50: 0.5nMAssay Description:Agonist activity at recombinant human V1b receptor expressed in HEK293 cells assessed as increase in intracellular calcium level measured at 3 secs i...More data for this Ligand-Target Pair
TargetVasopressin V1b receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 0.520nMAssay Description:Displacement of [3H]AVP from human vasopressin V1b receptor expressed CHO cells after 60 minsMore data for this Ligand-Target Pair
TargetVasopressin V1b receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 0.520nMAssay Description:Binding affinity against human vasopressin V1b receptor was determined by using plasma membranes from CHO cells stably transfected with VP/OT recepto...More data for this Ligand-Target Pair
TargetVasopressin V1b receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
TargetVasopressin V1b receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 0.600nMAssay Description:Displacement of [3H]Arg8-vasopressin from human vasopressin V1b receptor expressed in CHO-K1 cells by Packard Topcount scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Displacement of [3H]AVP from rat vasopressin V1b receptor expressed in At-T20 cellsMore data for this Ligand-Target Pair
TargetVasopressin V1b receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 0.600nMAssay Description:Displacement of [3H]AVP from human vasopressin V1b receptor expressed in CHO cells by whole cell binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Displacement of [3H]AVP from rat vasopressin V1b receptor expressed in At-T20 cellsMore data for this Ligand-Target Pair
TargetVasopressin V1b receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 0.610nMAssay Description:Displacement of [3H]AVP from human vasopressin V1b receptor expressed CHO cells after 60 minsMore data for this Ligand-Target Pair
TargetVasopressin V1b receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataIC50: 0.610nMpH: 7.4 T: 2°CAssay Description:Human V1b receptor was transiently expressed in 293FT cells (Invitrogen). The cells were collected and then homogenated in a 15 mmol/L tris-hydrochlo...More data for this Ligand-Target Pair
TargetVasopressin V1b receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataIC50: 0.610nMpH: 7.4 T: 2°CAssay Description:Human V1b receptor was transiently expressed in 293FT cells (Invitrogen). The cells were collected and then homogenated in a 15 mmol/L tris-hydrochlo...More data for this Ligand-Target Pair
TargetVasopressin V1b receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 0.650nMAssay Description:Displacement of [3H]AVP from human vasopressin V1b receptor expressed CHO cells after 60 minsMore data for this Ligand-Target Pair
TargetVasopressin V1b receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 0.740nMAssay Description:Test compounds were tested for binding to the V1b human vasopressin receptor using a human V1b (agonist radioligand) Receptor Binding Assay, with the...More data for this Ligand-Target Pair
TargetVasopressin V1b receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 0.780nMAssay Description:Binding affinity against human vasopressin V1b receptor was determined by using plasma membranes from CHO cells stably transfected with VP/OT recepto...More data for this Ligand-Target Pair
TargetVasopressin V1b receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataEC50: 0.800nMAssay Description:Agonist activity at recombinant human V1b receptor expressed in HEK293 cells assessed as increase in intracellular calcium level measured at 3 secs i...More data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Displacement of [3H]AVP from rat vasopressin V1b receptor expressed in At-T20 cellsMore data for this Ligand-Target Pair
TargetVasopressin V1b receptor(Human)
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Tohoku University and Department of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 0.810nMAssay Description:Displacement of [3H]AVP from human vasopressin V1b receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair








































