Compile Data Set for Download or QSAR
Report error Found 722 Enz. Inhib. hit(s) with Target = 'cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B'
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM677013(US11993596, Compound WX024 | US20240294526, Compou...)
Affinity DataIC50: 0.0400nMAssay Description:Experimental objective: to determine the AMP/GMP expression based on fluorescence polarization, i.e., to trace binding of AMP/GMP to antibody so as t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2024
Entry Details
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B [387-1112](Human)
Merck Research Laboratories

LigandPNGBDBM15311((5R)-5-methyl-6-{4-[(2-{[3-(3-nitrophenyl)phenyl]m...)
Affinity DataIC50: 0.0490nMpH: 7.5 T: 2°CAssay Description:PDE activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using scintillation proximity assay (SPA). [3H]-AMP was captured by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM677020(US11993596, Compound WX049 | US20240294526, Compou...)
Affinity DataIC50: 0.0500nMAssay Description:Experimental objective: to determine the AMP/GMP expression based on fluorescence polarization, i.e., to trace binding of AMP/GMP to antibody so as t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2024
Entry Details
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM677009(US11993596, Compound WX018 | US20240294526, Compou...)
Affinity DataIC50: 0.0500nMAssay Description:Experimental objective: to determine the AMP/GMP expression based on fluorescence polarization, i.e., to trace binding of AMP/GMP to antibody so as t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2024
Entry Details
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B [387-1112](Human)
Merck Research Laboratories

LigandPNGBDBM15310((5R)-5-methyl-6-{4-[(3-oxo-2-{[3-(thiophen-3-yl)ph...)
Affinity DataIC50: 0.0680nMpH: 7.5 T: 2°CAssay Description:PDE activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using scintillation proximity assay (SPA). [3H]-AMP was captured by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B [387-1112](Human)
Merck Research Laboratories

LigandPNGBDBM15337(dihydropyridazinone 14e | (5R)-6-[4-({2-[(3-iodoph...)
Affinity DataIC50: 0.110nMpH: 7.5 T: 2°CAssay Description:PDE activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using scintillation proximity assay (SPA). [3H]-AMP was captured by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM677003(US11993596, Compound WX004 | US20240294526, Compou...)
Affinity DataIC50: 0.120nMAssay Description:Experimental objective: to determine the AMP/GMP expression based on fluorescence polarization, i.e., to trace binding of AMP/GMP to antibody so as t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2024
Entry Details
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B [387-1112](Human)
Merck Research Laboratories

LigandPNGBDBM15329(3-[4-({2-[(2,6-dichlorophenyl)methyl]-3-oxocyclohe...)
Affinity DataIC50: 0.130nMAssay Description:PDE activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using scintillation proximity assay (SPA). [3H]-AMP was captured by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B [387-1112](Human)
Merck Research Laboratories

LigandPNGBDBM15304((5R)-6-[4-({2-[(2-methoxyphenyl)methyl]-3-oxocyclo...)
Affinity DataIC50: 0.130nMpH: 7.5 T: 2°CAssay Description:PDE activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using scintillation proximity assay (SPA). [3H]-AMP was captured by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM677018(US11993596, Compound WX047 | US20240294526, Compou...)
Affinity DataIC50: 0.160nMAssay Description:Experimental objective: to determine the AMP/GMP expression based on fluorescence polarization, i.e., to trace binding of AMP/GMP to antibody so as t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2024
Entry Details
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM677022(US11993596, Compound WX052 | US20240294526, Compou...)
Affinity DataIC50: 0.180nMAssay Description:Experimental objective: to determine the AMP/GMP expression based on fluorescence polarization, i.e., to trace binding of AMP/GMP to antibody so as t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2024
Entry Details
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B [387-1112](Human)
Merck Research Laboratories

LigandPNGBDBM15302((5R)-6-{4-[(2-benzyl-3-oxocyclohex-1-en-1-yl)amino...)
Affinity DataIC50: 0.190nMpH: 7.5 T: 2°CAssay Description:PDE activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using scintillation proximity assay (SPA). [3H]-AMP was captured by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM677007(US11993596, Compound WX016 | US20240294526, Compou...)
Affinity DataIC50: 0.240nMAssay Description:Experimental objective: to determine the AMP/GMP expression based on fluorescence polarization, i.e., to trace binding of AMP/GMP to antibody so as t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2024
Entry Details
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B [387-1112](Human)
Merck Research Laboratories

LigandPNGBDBM15318(6-{4-[(2-benzyl-3-oxocyclohex-1-en-1-yl)amino]-2-f...)
Affinity DataIC50: 0.240nMAssay Description:PDE activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using scintillation proximity assay (SPA). [3H]-AMP was captured by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM677021(US11993596, Compound WX050 | US20240294526, Compou...)
Affinity DataIC50: 0.240nMAssay Description:Experimental objective: to determine the AMP/GMP expression based on fluorescence polarization, i.e., to trace binding of AMP/GMP to antibody so as t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2024
Entry Details
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B [387-1112](Human)
Merck Research Laboratories

LigandPNGBDBM15319(6-{4-[(2-benzyl-3-oxocyclohex-1-en-1-yl)amino]-3-f...)
Affinity DataIC50: 0.260nMAssay Description:PDE activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using scintillation proximity assay (SPA). [3H]-AMP was captured by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B [654-1073](Human)
Merck Research Laboratories

LigandPNGBDBM15337(dihydropyridazinone 14e | (5R)-6-[4-({2-[(3-iodoph...)
Affinity DataIC50: 0.270nMpH: 7.5 T: 2°CAssay Description:PDE activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using scintillation proximity assay (SPA). [3H]-AMP was captured by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM50532267(CHEMBL131355)
Affinity DataIC50: 0.270nMAssay Description:Inhibition of human His-tagged PDE3B catalytic domain expressed in Escherichia coli BL21(DE3) pLysS cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM677019(US11993596, Compound WX048 | US20240294526, Compou...)
Affinity DataIC50: 0.270nMAssay Description:Experimental objective: to determine the AMP/GMP expression based on fluorescence polarization, i.e., to trace binding of AMP/GMP to antibody so as t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2024
Entry Details
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM50532267(CHEMBL131355)
Affinity DataIC50: 0.270nMAssay Description:Inhibition of human His-tagged PDE3B catalytic domain expressed in Escherichia coli BL21(DE3) pLysS cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B [387-1112](Human)
Merck Research Laboratories

LigandPNGBDBM15307((5R)-6-[4-({2-[(3-bromophenyl)methyl]-3-oxocyclohe...)
Affinity DataIC50: 0.300nMpH: 7.5 T: 2°CAssay Description:PDE activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using scintillation proximity assay (SPA). [3H]-AMP was captured by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B [387-1112](Human)
Merck Research Laboratories

LigandPNGBDBM15335(3-[(2-{[4-(4,4-dimethyl-5-oxo-4,5-dihydro-1H-pyraz...)
Affinity DataIC50: 0.330nMAssay Description:PDE activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using scintillation proximity assay (SPA). [3H]-AMP was captured by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B [387-1112](Human)
Merck Research Laboratories

LigandPNGBDBM15305((5R)-5-methyl-6-{4-[(3-oxo-2-{[2-(trifluoromethyl)...)
Affinity DataIC50: 0.350nMpH: 7.5 T: 2°CAssay Description:PDE activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using scintillation proximity assay (SPA). [3H]-AMP was captured by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM677016(US11993596, Compound WX036 | US20240294526, Compou...)
Affinity DataIC50: 0.410nMAssay Description:Experimental objective: to determine the AMP/GMP expression based on fluorescence polarization, i.e., to trace binding of AMP/GMP to antibody so as t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2024
Entry Details
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM677008(US11993596, Compound WX017 | US20240294526, Compou...)
Affinity DataIC50: 0.430nMAssay Description:Experimental objective: to determine the AMP/GMP expression based on fluorescence polarization, i.e., to trace binding of AMP/GMP to antibody so as t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2024
Entry Details
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM677014(US11993596, Compound WX025 | US20240294526, Compou...)
Affinity DataIC50: 0.440nMAssay Description:Experimental objective: to determine the AMP/GMP expression based on fluorescence polarization, i.e., to trace binding of AMP/GMP to antibody so as t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2024
Entry Details
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM677011(US11993596, Compound WX020 | US20240294526, Compou...)
Affinity DataIC50: 0.470nMAssay Description:Experimental objective: to determine the AMP/GMP expression based on fluorescence polarization, i.e., to trace binding of AMP/GMP to antibody so as t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2024
Entry Details
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM677010(US11993596, Compound WX019 | US20240294526, Compou...)
Affinity DataIC50: 0.480nMAssay Description:Experimental objective: to determine the AMP/GMP expression based on fluorescence polarization, i.e., to trace binding of AMP/GMP to antibody so as t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2024
Entry Details
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B [387-1112](Human)
Merck Research Laboratories

LigandPNGBDBM15328(3-[4-({2-[(2-chlorophenyl)methyl]-3-oxocyclohex-1-...)
Affinity DataIC50: 0.530nMAssay Description:PDE activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using scintillation proximity assay (SPA). [3H]-AMP was captured by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM677006(US11993596, Compound WX015 | US20240294526, Compou...)
Affinity DataIC50: 0.560nMAssay Description:Experimental objective: to determine the AMP/GMP expression based on fluorescence polarization, i.e., to trace binding of AMP/GMP to antibody so as t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2024
Entry Details
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B [387-1112](Human)
Merck Research Laboratories

LigandPNGBDBM15316(6-{4-[(2-benzyl-3-oxocyclohex-1-en-1-yl)amino]-3-m...)
Affinity DataIC50: 0.610nMAssay Description:PDE activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using scintillation proximity assay (SPA). [3H]-AMP was captured by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B [387-1112](Human)
Merck Research Laboratories

LigandPNGBDBM15321(6-{4-[(2-benzyl-3-oxocyclohex-1-en-1-yl)amino]-2,5...)
Affinity DataIC50: 0.620nMAssay Description:PDE activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using scintillation proximity assay (SPA). [3H]-AMP was captured by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B [387-1112](Human)
Merck Research Laboratories

LigandPNGBDBM15312((5R)-6-[4-({2-[(4-methoxyphenyl)methyl]-3-oxocyclo...)
Affinity DataIC50: 0.700nMpH: 7.5 T: 2°CAssay Description:PDE activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using scintillation proximity assay (SPA). [3H]-AMP was captured by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B [387-1112](Human)
Merck Research Laboratories

LigandPNGBDBM15306((5R)-6-[4-({2-[(3-fluorophenyl)methyl]-3-oxocycloh...)
Affinity DataIC50: 0.700nMpH: 7.5 T: 2°CAssay Description:PDE activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using scintillation proximity assay (SPA). [3H]-AMP was captured by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B [387-1112](Human)
Merck Research Laboratories

LigandPNGBDBM15309((5R)-5-methyl-6-[4-({2-[(3-nitrophenyl)methyl]-3-o...)
Affinity DataIC50: 0.940nMpH: 7.5 T: 2°CAssay Description:PDE activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using scintillation proximity assay (SPA). [3H]-AMP was captured by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B [387-1112](Human)
Merck Research Laboratories

LigandPNGBDBM15301(benzyl N-[4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyri...)
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:PDE activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using scintillation proximity assay (SPA). [3H]-AMP was captured by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM744654((5S)-6-[4-(cyclopentylamino)-3-(trifluoromethyl)ph...)
Affinity DataIC50: 1nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2025
Entry Details
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM744653((5S)-6-[4-(3-hydroxy-3-methylazetidin-1-yl)-3-(tri...)
Affinity DataIC50: 1nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2025
Entry Details
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B [387-1112](Human)
Merck Research Laboratories

LigandPNGBDBM15330(3-[2-fluoro-4-({2-[(2-fluorophenyl)methyl]-3-oxocy...)
Affinity DataIC50: 1.10nMAssay Description:PDE activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using scintillation proximity assay (SPA). [3H]-AMP was captured by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM677012(US11993596, Compound WX021 | US20240294526, Compou...)
Affinity DataIC50: 1.10nMAssay Description:Experimental objective: to determine the AMP/GMP expression based on fluorescence polarization, i.e., to trace binding of AMP/GMP to antibody so as t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2024
Entry Details
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM677028(US11993596, Compound WX064 | US20240294526, Compou...)
Affinity DataIC50: 1.40nMAssay Description:Experimental objective: to determine the AMP/GMP expression based on fluorescence polarization, i.e., to trace binding of AMP/GMP to antibody so as t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2024
Entry Details
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM677017(US11993596, Compound WX037 | US20240294526, Compou...)
Affinity DataIC50: 1.70nMAssay Description:Experimental objective: to determine the AMP/GMP expression based on fluorescence polarization, i.e., to trace binding of AMP/GMP to antibody so as t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2024
Entry Details
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM677023(US11993596, Compound WX053 | US20240294526, Compou...)
Affinity DataIC50: 1.90nMAssay Description:Experimental objective: to determine the AMP/GMP expression based on fluorescence polarization, i.e., to trace binding of AMP/GMP to antibody so as t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2024
Entry Details
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM677025(US11993596, Compound WX055 | US20240294526, Compou...)
Affinity DataIC50: 2.10nMAssay Description:Experimental objective: to determine the AMP/GMP expression based on fluorescence polarization, i.e., to trace binding of AMP/GMP to antibody so as t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2024
Entry Details
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM677002(US11993596, Compound WX003 | US20240294526, Compou...)
Affinity DataIC50: 2.20nMAssay Description:Experimental objective: to determine the AMP/GMP expression based on fluorescence polarization, i.e., to trace binding of AMP/GMP to antibody so as t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2024
Entry Details
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM677015(US11993596, Compound WX026 | US20240294526, Compou...)
Affinity DataIC50: 2.5nMAssay Description:Experimental objective: to determine the AMP/GMP expression based on fluorescence polarization, i.e., to trace binding of AMP/GMP to antibody so as t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2024
Entry Details
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B [387-1112](Human)
Merck Research Laboratories

LigandPNGBDBM15325(3-{4-[(2-benzyl-3-oxocyclohex-1-en-1-yl)amino]-2-f...)
Affinity DataIC50: 2.5nMAssay Description:PDE activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using scintillation proximity assay (SPA). [3H]-AMP was captured by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B [387-1112](Human)
Merck Research Laboratories

LigandPNGBDBM15314(6-{4-[(2-benzyl-3-oxocyclohex-1-en-1-yl)amino]-2-m...)
Affinity DataIC50: 2.60nMpH: 7.5 T: 2°CAssay Description:PDE activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using scintillation proximity assay (SPA). [3H]-AMP was captured by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM677024(US11993596, Compound WX054 | US20240294526, Compou...)
Affinity DataIC50: 2.70nMAssay Description:Experimental objective: to determine the AMP/GMP expression based on fluorescence polarization, i.e., to trace binding of AMP/GMP to antibody so as t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2024
Entry Details
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B [387-1112](Human)
Merck Research Laboratories

LigandPNGBDBM15332(3-[2-fluoro-4-({2-[(4-fluorophenyl)methyl]-3-oxocy...)
Affinity DataIC50: 3.10nMAssay Description:PDE activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using scintillation proximity assay (SPA). [3H]-AMP was captured by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
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