Compound Name

SMILES String

CN1C2=NCCN2c2ncn(CC(=O)Nc3nc(cs3)-c3ccc(Br)cc3)c2C1=O |t:2|

CN1C2=NCCN2c2ncn(CC(=O)Nc3nc(cs3)-c3ccc(cc3)C(C)(C)C)c2C1=O |t:2|

Cn1c2cccc(CC(=O)Nc3nc(cs3)-c3ccc(Br)cc3)c2c(=O)n(C)c1=O

Cn1c2cccc(CC(=O)Nc3nc(cs3)-c3ccc(Cl)c(Cl)c3)c2c(=O)n(C)c1=O

Cn1c2cccc(CC(=O)Nc3nc(cs3)-c3ccc(I)cc3)c2c(=O)n(C)c1=O

Cc1ccc(cc1)-c1csc(NC(=O)Cc2cccc3n(C)c(=O)n(C)c(=O)c23)n1

Cn1c2cccc(CC(=O)Nc3nc(cs3)-c3cccc(c3)C(F)(F)F)c2c(=O)n(C)c1=O

Cn1c2cccc(CC(=O)Nc3ccn(n3)-c3ccc(Cl)cc3)c2c(=O)n(C)c1=O

Cn1c2cccc(CC(=O)Nc3nc(cs3)-c3cccc(Cl)c3)c2c(=O)n(C)c1=O

Cn1c2cccc(CC(=O)Nc3nc(cs3)-c3ccc(cc3)C3CCCCC3)c2c(=O)n(C)c1=O

Cn1c2cccc(CC(=O)Nc3nc(cs3)-c3ccc(cc3)C(F)(F)F)c2c(=O)n(C)c1=O

Cn1c2cccc(CC(=O)Nc3nc(cs3)-c3ccc(cc3)C(C)(C)C)c2c(=O)n(C)c1=O

Cn1c2cccc(CC(=O)Nc3nc(cs3)-c3ccc(F)cc3F)c2c(=O)n(C)c1=O

CC(C)c1ccc(cc1)-c1csc(NC(=O)Cc2cccc3n(C)c(=O)n(C)c(=O)c23)n1

Cn1c2cccc(CC(=O)Nc3nc(cs3)-c3ccc(F)c(Cl)c3)c2c(=O)n(C)c1=O

Cn1c2cccc(CC(=O)Nc3ccn(n3)-c3cccc(c3)C(F)(F)F)c2c(=O)n(C)c1=O

CCc1ccc(cc1)-c1csc(NC(=O)Cc2cccc3n(C)c(=O)n(C)c(=O)c23)n1

Cn1c2cccc(CC(=O)Nc3nc(cs3)-c3ccc(c(F)c3)C(F)(F)F)c2c(=O)n(C)c1=O

Cn1c2cccc(CC(=O)Nc3nc(cs3)-c3ccc(cc3F)C(F)(F)F)c2c(=O)n(C)c1=O

Cn1c2cccc(CC(=O)Nc3nc(cs3)-c3ccc(F)c(c3)C(F)(F)F)c2c(=O)n(C)c1=O

Cn1c2cccc(CC(=O)Nc3nc(cs3)-c3ccc(Cl)c(c3)C(F)(F)F)c2c(=O)n(C)c1=O

CC(C)CCOc1ccc(cc1)-c1csc(NC(=O)Cc2cccc3n(C)c(=O)n(C)c(=O)c23)n1

CC(C)COc1ccc(cc1)-c1csc(NC(=O)Cc2cccc3n(C)c(=O)n(C)c(=O)c23)n1

Cn1c2cccc(CC(=O)Nc3nc(cs3)-c3cc(Cl)ccc3F)c2c(=O)n(C)c1=O

Cn1c2cccc(CC(=O)Nc3nc(cs3)-c3cccc(Cl)c3F)c2c(=O)n(C)c1=O

Cn1c2cccc(CC(=O)Nc3nc(cs3)-c3cccc(OC(F)(F)F)c3)c2c(=O)n(C)c1=O

Cn1c2cccc(CC(=O)Nc3nc(cs3)-c3cccc(F)c3F)c2c(=O)n(C)c1=O

Cn1c2cccc(CC(=O)Nc3nc(cs3)-c3ccc(c(F)c3F)C(F)(F)F)c2c(=O)n(C)c1=O

Cn1c2cccc(CC(=O)Nc3nc(cs3)-c3ccc(OC(F)(F)F)c(F)c3)c2c(=O)n(C)c1=O

Cn1c2cccc(CC(=O)Nc3nc(cs3)-c3ccc(OC(F)F)c(Cl)c3)c2c(=O)n(C)c1=O

Cn1c2cccc(CC(=O)Nc3nc(cs3)-c3ccc(F)c(c3F)C(F)(F)F)c2c(=O)n(C)c1=O

Cn1c2cccc(CC(=O)Nc3nc(cs3)-c3cc(F)c(OCC(F)(F)F)c(F)c3)c2c(=O)n(C)c1=O

Cn1c2cccc(CC(=O)Nc3nc(cs3)-c3cc(F)c(c(F)c3)C(F)(F)F)c2c(=O)n(C)c1=O

Cn1c2ccn(CC(=O)Nc3nc(cs3)-c3ccc(OC(F)(F)F)cc3)c2c(=O)n(C)c1=O

Cn1c2ccn(CC(=O)Nc3nc(cs3)-c3cc(Cl)c(OCCC(F)(F)F)c(Cl)c3)c2c(=O)n(C)c1=O

Cn1c2ccn(CC(=O)Nc3nc(cs3)-c3ccc(c(F)c3)C(F)(F)F)c2c(=O)n(C)c1=O

Cn1c2cnn(CC(=O)Nc3nc(cs3)-c3cc(Cl)c(OCC(C)(C)C)c(Cl)c3)c2c(=O)n(C)c1=O

Cn1nc2n(C)c(=O)n(C)c(=O)c2c1CC(=O)Nc1nc(cs1)-c1ccc(c(F)c1)C(F)(F)F

Cn1nc2n(C)c(=O)n(C)c(=O)c2c1CC(=O)Nc1nc(cs1)-c1ccc(cc1)C(F)(F)F

Cn1c2cnn(CC(=O)Nc3nc(cs3)-c3cc(F)c(OCC(C)(C)C)c(F)c3)c2c(=O)n(C)c1=O

Cn1nc2n(C)c(=O)n(C)c(=O)c2c1CC(=O)Nc1nc(cs1)-c1ccc(OC(F)(F)F)c(F)c1

Cn1c2cnn(CC(=O)Nc3nc(cs3)-c3cc(F)c(OCC(C)(C)C)c(Cl)c3)c2c(=O)n(C)c1=O

Cn1c2cnn(CC(=O)Nc3nc(cs3)-c3cc(F)c(OCC4CCC4)c(F)c3)c2c(=O)n(C)c1=O

Cn1c2cnn(CC(=O)Nc3nc(cs3)-c3ccc(OCC(C)(C)C)c(F)c3)c2c(=O)n(C)c1=O

CC(C)c1sc2n(C)c(=O)n(C)c(=O)c2c1CC(=O)Nc1nc(cs1)-c1ccc(c(F)c1)C(F)(F)F

Cc1sc2n(C)c(=O)n(C)c(=O)c2c1CC(=O)Nc1nc(cs1)-c1ccc(Cl)c(Cl)c1

CCc1sc2n(C)c(=O)n(C)c(=O)c2c1CC(=O)Nc1nc(cs1)-c1cc(F)c(OC(F)F)c(F)c1

CCc1sc2n(C)c(=O)n(C)c(=O)c2c1CC(=O)Nc1nc(cs1)-c1cc(F)c(OCC(F)(F)F)c(F)c1

CCc1sc2n(C)c(=O)n(C)c(=O)c2c1CC(=O)Nc1nc(cs1)-c1ccc(c(F)c1)C(F)(F)F

Cn1c2scc(CC(=O)Nc3nc(cs3)-c3ccc(F)c(c3F)C(F)(F)F)c2c(=O)n(C)c1=O

CC(C)COc1c(F)cc(cc1F)-c1csc(NC(=O)Cc2coc3n(C)c(=O)n(C)c(=O)c23)n1

Cn1c2occ(CC(=O)Nc3nc(cs3)-c3ccc(c(F)c3)C(F)(F)F)c2c(=O)n(C)c1=O

Cn1c2occ(CC(=O)Nc3nc(cs3)-c3cc(F)cc(c3)C(F)(F)F)c2c(=O)n(C)c1=O

Cn1c2occ(CC(=O)Nc3nc(cs3)-c3cc(F)c(CCC(F)(F)F)c(F)c3)c2c(=O)n(C)c1=O

Cn1c2occ(CC(=O)Nc3nc(cs3)-c3cc(Cl)c(OCC(F)(F)F)c(Cl)c3)c2c(=O)n(C)c1=O

Cn1c2occ(CC(=O)Nc3nc(cs3)-c3ccc(F)c(c3)C(F)(F)F)c2c(=O)n(C)c1=O

Cn1c2occ(CC(=O)Nc3nc(cs3)-c3cccc(c3F)C(F)(F)F)c2c(=O)n(C)c1=O

Cn1c2occ(CC(=O)Nc3nc(cs3)-c3cc(F)c(OCC(F)(F)F)c(Cl)c3)c2c(=O)n(C)c1=O

Cc1oc2n(C)c(=O)n(C)c(=O)c2c1CC(=O)Nc1nc(cs1)-c1cc(F)cc(c1)C(F)(F)F

Cc1oc2n(C)c(=O)n(C)c(=O)c2c1CC(=O)Nc1nc(cs1)-c1cc(F)c(OCC(F)(F)F)c(F)c1

Cc1oc2n(C)c(=O)n(C)c(=O)c2c1CC(=O)Nc1nc(cs1)-c1ccc(Cl)c(OC(F)(F)F)c1

Cc1oc2n(C)c(=O)n(C)c(=O)c2c1CC(=O)Nc1nc(cs1)-c1ccc(F)c(c1F)C(F)(F)F

Cc1oc2n(C)c(=O)n(C)c(=O)c2c1CC(=O)Nc1nc(cs1)-c1ccc(cc1F)C(F)(F)F

Cc1oc2n(C)c(=O)n(C)c(=O)c2c1CC(=O)Nc1nc(cs1)-c1cc(F)c(OCC(C)(C)C)c(F)c1

Cc1oc2n(C)c(=O)n(C)c(=O)c2c1CC(=O)Nc1nc(cs1)-c1cccc(c1F)C(F)(F)F

Cc1oc2n(C)c(=O)n(C)c(=O)c2c1CC(=O)Nc1nc(cs1)-c1ccc(F)c(OC(F)(F)F)c1

Cc1oc2n(C)c(=O)n(C)c(=O)c2c1CC(=O)Nc1nc(cs1)-c1ccc(F)c(c1)C(F)(F)F

Cc1oc2n(C)c(=O)n(C)c(=O)c2c1CC(=O)Nc1nc(cs1)-c1ccc(OC(F)(F)F)c(F)c1

Cc1oc2n(C)c(=O)n(C)c(=O)c2c1CC(=O)Nc1nc(cs1)-c1ccc(Cl)c(c1)C(F)(F)F

Cc1oc2n(C)c(=O)n(C)c(=O)c2c1CC(=O)Nc1nc(cs1)-c1cc(F)c(c(F)c1)C(F)(F)F

Cc1oc2n(C)c(=O)n(C)c(=O)c2c1CC(=O)Nc1nc(cs1)-c1ccc(OC(F)(F)F)c(Cl)c1

Cc1oc2n(C)c(=O)n(C)c(=O)c2c1CC(=O)Nc1nc(cs1)-c1ccc(OCC(F)(F)F)c(Cl)c1

CC(C)COc1c(Cl)cc(cc1Cl)-c1csc(NC(=O)Cc2c(C)oc3n(C)c(=O)n(C)c(=O)c23)n1

Cc1oc2n(C)c(=O)n(C)c(=O)c2c1CC(=O)Nc1nc(cs1)-c1ccc(c(F)c1F)C(F)(F)F

Cn1c2snc(CC(=O)Nc3nc(cs3)-c3ccc(F)c(c3F)C(F)(F)F)c2c(=O)n(C)c1=O

Cn1c2snc(CC(=O)Nc3nc(cs3)-c3ccc(cc3F)C(F)(F)F)c2c(=O)n(C)c1=O

Cn1c2snc(CC(=O)Nc3nc(cs3)-c3cccc(c3F)C(F)(F)F)c2c(=O)n(C)c1=O

Cn1c2snc(CC(=O)Nc3nc(cs3)-c3ccc(OC(F)(F)F)c(Cl)c3)c2c(=O)n(C)c1=O

Cn1c2snc(CC(=O)Nc3nc(cs3)-c3ccc(c(F)c3)C(F)(F)F)c2c(=O)n(C)c1=O

Cn1c2snc(CC(=O)Nc3nc(cs3)-c3ccc(OC(F)(F)F)c(F)c3)c2c(=O)n(C)c1=O

Cn1c2snc(CC(=O)Nc3nc(cs3)-c3cc(F)cc(c3)C(F)(F)F)c2c(=O)n(C)c1=O

Cn1c2snc(CC(=O)Nc3nc(cs3)-c3ccc(c(F)c3F)C(F)(F)F)c2c(=O)n(C)c1=O

Cn1c2nccc(CC(=O)Nc3nc(cs3)-c3ccc(c(F)c3)C(F)(F)F)c2c(=O)n(C)c1=O

Cn1c2nccc(CC(=O)Nc3nc(cs3)-c3cc(F)c(OCC(F)(F)F)c(F)c3)c2c(=O)n(C)c1=O

Cn1c2nccc(CC(=O)Nc3nc(cs3)-c3ccc(F)c(c3F)C(F)(F)F)c2c(=O)n(C)c1=O

Cn1c2nccc(CC(=O)Nc3nc(cs3)-c3ccc(OC(F)(F)F)c(F)c3)c2c(=O)n(C)c1=O

CC\C(=N/O)\C(\C)=C\c1ccc(F)cc1

COCCCOc1cccc(c1)C1NC(=S)NC2=C1C(=O)c1ccccc21 |c:18|

Cn1c2ncn(CC(=O)Nc3nc(cs3)-c3ccc(Br)cc3)c2c(=O)n(C)c1=O

Cn1c2noc(CC(=O)Nc3nc(cs3)-c3ccc(F)c(c3F)C(F)(F)F)c2c(=O)n(C)c1=O

Cc1oc2n(C)c(=O)n(C)c(=O)c2c1CC(=O)\N=c1/scc(-c2ccc(OC(F)(F)F)c(Cl)c2)n1COP(O)(O)=O

Cn1nc2n(C)c(=O)n(C)c(=O)c2c1CC(=O)\N=c1/scc(-c2ccc(F)c(c2F)C(F)(F)F)n1COP(O)(O)=O

CC(C)[C@H](N)C(=O)OCn1c(cs\c1=N/C(=O)Cc1c(C)oc2n(C)c(=O)n(C)c(=O)c12)-c1ccc(OC(F)(F)F)c(Cl)c1 |r|

Cn1c2oc(Cl)c(CC(=O)Nc3nc(cs3)-c3ccc(c(F)c3)C(F)(F)F)c2c(=O)n(C)c1=O

Cn1c2oc(Cl)c(CC(=O)Nc3nc(cs3)-c3cc(F)cc(c3)C(F)(F)F)c2c(=O)n(C)c1=O

Cn1c2oc(Cl)c(CC(=O)Nc3nc(cs3)-c3ccc(F)c(c3F)C(F)(F)F)c2c(=O)n(C)c1=O

Cn1c2oc(Cl)c(CC(=O)Nc3nc(cs3)-c3ccc(OC(F)(F)F)c(F)c3)c2c(=O)n(C)c1=O

Cn1c2oc(Cl)c(CC(=O)Nc3nc(cs3)-c3ccc(F)c(OC(F)(F)F)c3)c2c(=O)n(C)c1=O

Cn1c2oc(Cl)c(CC(=O)Nc3nc(cs3)-c3ccc(c(F)c3F)C(F)(F)F)c2c(=O)n(C)c1=O

Cc1c(cc(n1CCCN1CCOCC1)C(C)(C)C)C(=O)Nc1cccc(c1)C(F)(F)F

Cc1c(cc(-c2ccccc2)n1CCCO)C(=O)Nc1cccc(c1)C(F)(F)F

Cc1c(ccn1CCCN1CCOCC1)C(=O)Nc1cccc(c1)C(F)(F)F

Cc1c(cc(-c2ccccc2)n1CCCN1CCCCC1)C(=O)Nc1cccc(c1)C(F)(F)F

Cc1c(cc(-c2ccccc2)n1CCCN1CCOCC1)C(=O)Nc1ccccc1

COCCCn1c(C)c(cc1-c1ccccc1)C(=O)Nc1cccc(c1)C(F)(F)F

CC(=O)N1CCN(CCCn2c(C)c(cc2-c2ccccc2)C(=O)Nc2cccc(c2)C(F)(F)F)CC1

Cc1c(cc(-c2ccccc2)n1CCCN(CCO)CCO)C(=O)Nc1cccc(c1)C(F)(F)F

CN(C)CCCn1c(C)c(cc1-c1ccccc1)C(=O)Nc1cccc(c1)C(F)(F)F

Cc1c(cc(-c2cccnc2)n1CCCN1CCOCC1)C(=O)Nc1cccc(c1)C(F)(F)F

Cc1c(cc(-c2ccccc2)n1CCCN1CCOCC1)C(=O)Nc1ccccc1C(F)(F)F

Cc1c(cc(-c2ccccc2)n1CCCN1CCOCC1)C(=O)Nc1ccc(cc1)C(F)(F)F

CC(=O)NCCCn1c(C)c(cc1-c1ccccc1)C(=O)Nc1cccc(c1)C(F)(F)F

Cc1c(cc(-c2ccccc2)n1CCCNS(C)(=O)=O)C(=O)Nc1cccc(c1)C(F)(F)F

COC(=O)NCCCn1c(C)c(cc1-c1ccccc1)C(=O)Nc1cccc(c1)C(F)(F)F

FC(F)(F)c1c(cc(-c2ccccc2)n1CCCN1CCOCC1)C(=O)Nc1cccc(c1)C(F)(F)F

CC(C)CN(C)CCCn1c(C)c(cc1-c1ccccc1)C(=O)Nc1cccc(c1)C(F)(F)F

CN(CCCn1c(C)c(cc1-c1ccccc1)C(=O)Nc1cccc(c1)C(F)(F)F)C(=O)C1CCCC1

CN(CCCn1c(C)c(cc1-c1ccccc1)C(=O)Nc1cccc(c1)C(F)(F)F)C(=O)c1ccno1

CN(CCCn1c(C)c(cc1-c1ccccc1)C(=O)Nc1cccc(c1)C(F)(F)F)C(C)=O

Cc1c(cc(-c2ccccc2)n1CCCN1CCNC(=O)C1)C(=O)Nc1cccc(c1)C(F)(F)F

Cc1c(cc(C2CCCCC2)n1CCCN1CCOCC1)C(=O)Nc1cccc(c1)C(F)(F)F

Cc1c(cc(-c2ccccn2)n1CCCN1CCOCC1)C(=O)Nc1cccc(c1)C(F)(F)F

Cc1c(cc(-c2ccncc2)n1CCCN1CCOCC1)C(=O)Nc1cccc(c1)C(F)(F)F

Cc1c(cc(C2CCN(CC2)C(=O)OCc2ccccc2)n1CCCN1CCOCC1)C(=O)Nc1cccc(c1)C(F)(F)F

Cc1c(cc(C2CCNCC2)n1CCCN1CCOCC1)C(=O)Nc1cccc(c1)C(F)(F)F

CC(=O)N1CCC(CC1)c1cc(C(=O)Nc2cccc(c2)C(F)(F)F)c(C)n1CCCN1CCOCC1

Cc1c(cc(C2CCN(CC2)S(C)(=O)=O)n1CCCN1CCOCC1)C(=O)Nc1cccc(c1)C(F)(F)F

Cc1c(cc(C#N)n1CCCN1CCOCC1)C(=O)Nc1cccc(c1)C(F)(F)F

Cc1c(NS(=O)(=O)c2cccc(c2)C(F)(F)F)cc(-c2ccccc2)n1CCCN1CCOCC1

Cc1c(NC(=O)Nc2cccc(c2)C(F)(F)F)cc(-c2ccccc2)n1CCCN1CCOCC1

Cc1c(cc(-c2ccccc2)n1CCN1CCOCC1)C(=O)Nc1cccc(c1)C(F)(F)F

Cc1c(cc(-c2ccccc2)n1CCSCc1c(F)cccc1Cl)C(=O)Nc1cccc(c1)C(F)(F)F

FC(F)(F)c1cccc(NC(=O)c2cc(nn2CCCN2CCOCC2)-c2ccccc2)c1

FC(F)(F)c1cccc(NC(=O)c2cc(-c3ccccc3)n(CCCN3CCOCC3)n2)c1

Cc1c(nc(-c2ccccc2)n1CCCN1CCOCC1)C(=O)Nc1cccc(c1)C(F)(F)F

FC(F)(F)c1cccc(NC(=O)c2cnc(c(CCCN3CCOCC3)c2)-c2ccccc2)c1

FC(F)(F)c5cccc(Nc1ccc3c(c1)cc(c2ccccc2)n3CCCN4CCOCC4)c5

CCOC(=O)CCn1c(C)c(cc1C(C)(C)C)C(=O)Nc1cccc(c1)C(F)(F)F

Cc1c(cc(n1CCC(=O)N1CCOCC1)C(C)(C)C)C(=O)Nc1cccc(c1)C(F)(F)F

CNC(=O)CCn1c(C)c(cc1C(C)(C)C)C(=O)Nc1cccc(c1)C(F)(F)F

Cc1c(cc(n1CCC(=O)N1CCNCC1)C(C)(C)C)C(=O)Nc1cccc(c1)C(F)(F)F

CNS(=O)(=O)CCn1c(C)c(cc1C(C)(C)C)C(=O)Nc1cccc(c1)C(F)(F)F

Cc1c(cc(n1CCS(=O)(=O)N1CCOCC1)C(C)(C)C)C(=O)Nc1cccc(c1)C(F)(F)F

CNC(C)CCn1c(C)c(cc1C(C)(C)C)C(=O)Nc1cccc(c1)C(F)(F)F

CC(CCn1c(C)c(cc1C(C)(C)C)C(=O)Nc1cccc(c1)C(F)(F)F)N1CCOCC1

Cc1c(cc(n1CCS(=O)(=O)N1CCNCC1)C(C)(C)C)C(=O)Nc1cccc(c1)C(F)(F)F

Cc1c(cc(n1C1CCNCC1)C(C)(C)C)C(=O)Nc1cccc(c1)C(F)(F)F

CNCC(C)(C)Cn1c(C)c(cc1C(C)(C)C)C(=O)Nc1cccc(c1)C(F)(F)F

CC(=O)N1CCC(CC1)n1c(C)c(cc1C(C)(C)C)C(=O)Nc1cccc(c1)C(F)(F)F

Cc1c(cc(n1C1CCN(CC1)S(C)(=O)=O)C(C)(C)C)C(=O)Nc1cccc(c1)C(F)(F)F

CNCCCn1c(C)c(cc1C(C)(C)C)S(=O)(=O)NCc1cccc(c1)C(F)(F)F

Cc1c(cc(n1CCCN1CCOCC1)C(C)(C)C)S(=O)(=O)NCc1cccc(c1)C(F)(F)F

Cc1c(cc(n1CCCN1CCNCC1)C(C)(C)C)S(=O)(=O)NCc1cccc(c1)C(F)(F)F

CN1CCC(CC1)n1c(C)c(cc1C(C)(C)C)C(=O)Nc1cccc(c1)C(F)(F)F

COC(=O)CN1CCC(CC1)n1c(C)c(cc1C(C)(C)C)C(=O)Nc1cccc(c1)C(F)(F)F

Cc1c(cc(n1CC(C)(C)CN1CCOCC1)C(C)(C)C)C(=O)Nc1cccc(c1)C(F)(F)F

Cc1c(cc(n1C1CCN(CC1)C1CCNCC1)C(C)(C)C)C(=O)Nc1cccc(c1)C(F)(F)F

Cc1c(cc(n1C1CCN(CCO)CC1)C(C)(C)C)C(=O)Nc1cccc(c1)C(F)(F)F

Cc1c(cc(n1[C@H]1CC[C@H](N)CC1)C(C)(C)C)C(=O)Nc1cccc(c1)C(F)(F)F |r,wU:6.6,wD:9.10,(-.52,.49,;-1.85,1.26,;-2.33,2.72,;-3.87,2.72,;-4.34,1.26,;-3.1,.36,;-3.1,-1.18,;-1.76,-1.95,;-1.76,-3.49,;-3.1,-4.26,;-3.1,-5.8,;-4.43,-3.49,;-4.43,-1.95,;-5.68,.49,;-7.01,1.26,;-7.01,-.28,;-5.68,-1.05,;-.99,3.49,;-.99,5.03,;.34,2.72,;1.67,3.49,;1.67,5.03,;3.01,5.8,;4.34,5.03,;4.39,3.47,;3.01,2.72,;5.72,2.7,;7.06,1.93,;4.95,1.36,;6.49,4.03,)|

CN[C@H]1CC[C@@H](CC1)n1c(C)c(cc1C(C)(C)C)C(=O)Nc1cccc(c1)C(F)(F)F |r,wU:5.8,wD:2.1,(-4.43,-6.19,;-3.1,-5.42,;-3.1,-3.88,;-1.76,-3.11,;-1.76,-1.57,;-3.1,-.8,;-4.43,-1.57,;-4.43,-3.11,;-3.1,.74,;-1.85,1.65,;-.52,.88,;-2.33,3.11,;-3.87,3.11,;-4.34,1.65,;-5.68,.88,;-7.01,1.65,;-7.01,.11,;-5.68,-.66,;-.99,3.88,;-.99,5.42,;.34,3.11,;1.67,3.88,;1.67,5.42,;3.01,6.19,;4.34,5.42,;4.39,3.85,;3.01,3.11,;5.72,3.08,;7.06,2.31,;4.95,1.75,;6.49,4.42,)|

CN(C)[C@H]1CC[C@@H](CC1)n1c(C)c(cc1C(C)(C)C)C(=O)Nc1cccc(c1)C(F)(F)F |r,wU:6.9,wD:3.2,(-4.43,-6.19,;-3.1,-5.42,;-1.76,-6.19,;-3.1,-3.88,;-1.76,-3.11,;-1.76,-1.57,;-3.1,-.8,;-4.43,-1.57,;-4.43,-3.11,;-3.1,.74,;-1.85,1.65,;-.52,.88,;-2.33,3.11,;-3.87,3.11,;-4.34,1.65,;-5.68,.88,;-7.01,1.65,;-7.01,.11,;-5.68,-.66,;-.99,3.88,;-.99,5.42,;.34,3.11,;1.67,3.88,;1.67,5.42,;3.01,6.19,;4.34,5.42,;4.39,3.85,;3.01,3.11,;5.72,3.08,;7.06,2.31,;4.95,1.75,;6.49,4.42,)|

Cc1c(cc(n1[C@H]1CC[C@@H](CC1)NS(C)(=O)=O)C(C)(C)C)C(=O)Nc1cccc(c1)C(F)(F)F |r,wU:6.6,wD:9.13,(-.52,1.65,;-1.85,2.42,;-2.33,3.88,;-3.87,3.88,;-4.34,2.42,;-3.1,1.51,;-3.1,-.03,;-1.76,-.8,;-1.76,-2.34,;-3.1,-3.11,;-4.43,-2.34,;-4.43,-.8,;-3.1,-4.65,;-1.76,-5.42,;-1.76,-6.96,;-.43,-6.19,;-.99,-4.09,;-5.68,1.65,;-7.01,2.42,;-7.01,.88,;-5.68,.11,;-.99,4.65,;-.99,6.19,;.34,3.88,;1.67,4.65,;1.67,6.19,;3.01,6.96,;4.34,6.19,;4.39,4.62,;3.01,3.88,;5.72,3.85,;7.06,3.08,;4.95,2.52,;6.49,5.19,)|

Cc1c(cc(n1[C@@H]1CC[C@@H](CC1)NS(C)(=O)=O)C(C)(C)C)C(=O)Nc1cccc(c1)C(F)(F)F |r,wU:6.6,9.13,(-.52,1.65,;-1.85,2.42,;-2.33,3.88,;-3.87,3.88,;-4.34,2.42,;-3.1,1.51,;-3.1,-.03,;-4.43,-.8,;-4.43,-2.34,;-3.1,-3.11,;-1.76,-2.34,;-1.76,-.8,;-3.1,-4.65,;-1.76,-5.42,;-1.76,-6.96,;-.99,-4.09,;-.22,-5.42,;-5.68,1.65,;-7.01,2.42,;-7.01,.88,;-5.68,.11,;-.99,4.65,;-.99,6.19,;.34,3.88,;1.67,4.65,;1.67,6.19,;3.01,6.96,;4.34,6.19,;4.39,4.62,;3.01,3.88,;5.72,3.85,;7.06,3.08,;4.95,2.52,;6.49,5.19,)|

Cc1c(cc(n1[C@@H]1CC[C@H](N)CC1)C(C)(C)C)C(=O)Nc1cccc(c1)C(F)(F)F |r,wU:6.6,9.10,(-.52,.49,;-1.85,1.26,;-2.33,2.72,;-3.87,2.72,;-4.34,1.26,;-3.1,.36,;-3.1,-1.18,;-4.43,-1.95,;-4.43,-3.49,;-3.1,-4.26,;-3.1,-5.8,;-1.76,-3.49,;-1.76,-1.95,;-5.68,.49,;-7.01,1.26,;-7.01,-.28,;-5.68,-1.05,;-.99,3.49,;-.99,5.03,;.34,2.72,;1.67,3.49,;1.67,5.03,;3.01,5.8,;4.34,5.03,;4.39,3.47,;3.01,2.72,;5.72,2.7,;7.06,1.93,;4.95,1.36,;6.49,4.03,)|

CNCCCn1c(C)c(cc1C(C)(C)C)S(=O)(=O)Nc1cccc(c1)C(F)(F)F

Cc1c(cc(n1CCCN1CCOCC1)C(C)(C)C)S(=O)(=O)Nc1cccc(c1)C(F)(F)F

CN[C@H]1CC[C@H](CC1)n1c(C)c(cc1C(C)(C)C)S(=O)(=O)Nc1cccc(c1)C(F)(F)F |r,wU:5.8,2.1,(-1.76,-6.19,;-3.1,-5.42,;-3.1,-3.88,;-4.43,-3.11,;-4.43,-1.57,;-3.1,-.8,;-1.76,-1.57,;-1.76,-3.11,;-3.1,.74,;-1.85,1.65,;-.52,.88,;-2.33,3.11,;-3.87,3.11,;-4.34,1.65,;-5.68,.88,;-7.01,1.65,;-7.01,.11,;-5.68,-.66,;-.99,3.88,;-1.76,5.21,;-.22,5.21,;.34,3.11,;1.67,3.88,;1.67,5.42,;3.01,6.19,;4.34,5.42,;4.39,3.85,;3.01,3.11,;5.72,3.08,;7.06,2.31,;4.95,1.75,;6.49,4.42,)|

CN([C@H]1CC[C@H](CC1)n1c(C)c(cc1C(C)(C)C)C(=O)Nc1cccc(c1)C(F)(F)F)S(C)(=O)=O |r,wU:5.8,2.1,(-4.43,-5.52,;-3.1,-4.75,;-3.1,-3.21,;-4.43,-2.44,;-4.43,-.9,;-3.1,-.13,;-1.76,-.9,;-1.76,-2.44,;-3.1,1.41,;-1.85,2.31,;-.52,1.54,;-2.33,3.78,;-3.87,3.78,;-4.34,2.31,;-5.68,1.54,;-7.01,2.31,;-7.01,.77,;-5.68,0,;-.99,4.55,;-.99,6.09,;.34,3.78,;1.67,4.55,;1.67,6.09,;3.01,6.86,;4.34,6.09,;4.39,4.52,;3.01,3.78,;5.72,3.75,;7.06,2.98,;4.95,2.42,;6.49,5.08,;-1.76,-5.52,;-.43,-4.75,;-2.53,-6.86,;-.99,-6.86,)|

CNCC(F)(F)Cn1c(C)c(cc1C(C)(C)C)C(=O)Nc1cccc(c1)C(F)(F)F

Cc1c(cc(n1CC(F)(F)CN1CCOCC1)C(C)(C)C)C(=O)Nc1cccc(c1)C(F)(F)F

Cc1c(cc(n1CC(C)(C)CN1CCNCC1)C(C)(C)C)C(=O)Nc1cccc(c1)C(F)(F)F

CC(CCn1c(C)c(cc1C(C)(C)C)C(=O)Nc1cccc(c1)C(F)(F)F)N1CCNCC1

Cc1c(cc(n1CC(F)(F)CN1CCNCC1)C(C)(C)C)C(=O)Nc1cccc(c1)C(F)(F)F

Cc1c(cc(n1CCCN1CCNCC1)C(C)(C)C)-c1nc2ccccc2o1

Cc1c(cc(n1CCCN1CCOCC1)C(C)(C)C)-c1nc2ccccc2[nH]1

Cc1c(cc(n1CCCN1CCNCC1)C(C)(C)C)-c1nc2ccccc2[nH]1

CNCCCn1c(C)c(cc1C(C)(C)C)-c1nc2ccccc2[nH]1

Cc1c(cc(n1CCCN1CCOCC1)C(C)(C)C)C(=O)OCc1ccccc1

Cc1c(cc(-c2ccccc2)n1CCCN1CCOCC1)C(=O)Nc1cnccn1

Cc1c(cc(-c2ccccc2)n1CCCN1CCOCC1)C(=O)Nc1ccc(Cl)cn1

CCOC(=O)Cc1csc(NC(=O)c2cc(-c3ccccc3)n(CCCN3CCOCC3)c2C)n1

Cc1c(cc(-c2ccccc2)n1CCCNc1ccccc1)C(=O)Nc1cccc(c1)C(F)(F)F

CN(CCCn1c(C)c(cc1-c1ccccc1)C(=O)Nc1cccc(c1)C(F)(F)F)c1ccccc1

Cc1c(cc(-c2ccccc2)n1CCCN1CCOCC1)C(=O)Nc1cccc(Cl)c1

Cc1c(cc(-c2ccccc2)n1CCCN1CCNCC1)C(=O)Nc1cccc(c1)C(F)(F)F

Cc1cc(C(=O)Nc2cccc(c2)C(F)(F)F)c(C)n1CCCN1CCOCC1

Cc1c(cc(-c2ccccc2)n1CCCN1CCOCC1)C(=O)Nc1nccs1

Cc1c(cc(-c2ccccc2)n1CCCN1CCOCC1)C(=O)Nc1nc2ccccc2s1

Cc1c(cc(-c2ccccc2)n1CCCN)C(=O)Nc1cccc(c1)C(F)(F)F

CC(C)c1cccc(NC(=O)c2cc(-c3ccccc3)n(CCCN3CCOCC3)c2C)c1

CN(CCCn1c(C)c(cc1-c1ccccc1)C(=O)Nc1cccc(c1)C(F)(F)F)C(=O)OC(C)(C)C

CNCCCn1c(C)c(cc1-c1ccccc1)C(=O)Nc1cccc(c1)C(F)(F)F

CN(CCCn1c(C)c(cc1-c1ccccc1)C(=O)Nc1cccc(c1)C(F)(F)F)CC1CC1

CN(CCCn1c(C)c(cc1-c1ccccc1)C(=O)Nc1cccc(c1)C(F)(F)F)CCOCc1ccccc1

CN(CCCn1c(C)c(cc1-c1ccccc1)C(=O)Nc1cccc(c1)C(F)(F)F)CC[C@H](O)[C@H](O)CO |r|

CN(CCCn1c(C)c(cc1-c1ccccc1)C(=O)Nc1cccc(c1)C(F)(F)F)CC1CCOC1

CCOC(=O)C1CC1CN(C)CCCn1c(C)c(cc1-c1ccccc1)C(=O)Nc1cccc(c1)C(F)(F)F

CN(C)CC(C)(C)CN(C)CCCn1c(C)c(cc1-c1ccccc1)C(=O)Nc1cccc(c1)C(F)(F)F

CN(CCCn1c(C)c(cc1-c1ccccc1)C(=O)Nc1cccc(c1)C(F)(F)F)CC1CCN(C)CC1

CN(CCCn1c(C)c(cc1-c1ccccc1)C(=O)Nc1cccc(c1)C(F)(F)F)CC1CCOCC1

COC(=O)CCCN(C)CCCn1c(C)c(cc1-c1ccccc1)C(=O)Nc1cccc(c1)C(F)(F)F

CN(CCCn1c(C)c(cc1-c1ccccc1)C(=O)Nc1cccc(c1)C(F)(F)F)C(=O)C1CCCCC1

CN(CCCn1c(C)c(cc1-c1ccccc1)C(=O)Nc1cccc(c1)C(F)(F)F)C(=O)c1ccco1

CN(CCCn1c(C)c(cc1-c1ccccc1)C(=O)Nc1cccc(c1)C(F)(F)F)C(=O)c1cccs1

COCC(=O)N(C)CCCn1c(C)c(cc1-c1ccccc1)C(=O)Nc1cccc(c1)C(F)(F)F

CN(CCCn1c(C)c(cc1-c1ccccc1)C(=O)Nc1cccc(c1)C(F)(F)F)C(=O)Cc1cccs1

CN(CCCn1c(C)c(cc1-c1ccccc1)C(=O)Nc1cccc(c1)C(F)(F)F)C(=O)c1ccncc1

CN(CCCn1c(C)c(cc1-c1ccccc1)C(=O)Nc1cccc(c1)C(F)(F)F)C(=O)c1ccc2OCOc2c1

COCCOCC(=O)N(C)CCCn1c(C)c(cc1-c1ccccc1)C(=O)Nc1cccc(c1)C(F)(F)F

CC(C)C(=O)N(C)CCCn1c(C)c(cc1-c1ccccc1)C(=O)Nc1cccc(c1)C(F)(F)F

CN(CCCn1c(C)c(cc1-c1ccccc1)C(=O)Nc1cccc(c1)C(F)(F)F)C(=O)C1CC1

CN(CCCn1c(C)c(cc1-c1ccccc1)C(=O)Nc1cccc(c1)C(F)(F)F)C(=O)c1cccnc1

CN(CCCn1c(C)c(cc1-c1ccccc1)C(=O)Nc1cccc(c1)C(F)(F)F)C(=O)c1ccccn1

CN(CCCn1c(C)c(cc1-c1ccccc1)C(=O)Nc1cccc(c1)C(F)(F)F)C(=O)c1ccc2ccccc2n1

CN(CCCn1c(C)c(cc1-c1ccccc1)C(=O)Nc1cccc(c1)C(F)(F)F)C(=O)c1ccc(NC(C)=O)cc1

CN(CCCn1c(C)c(cc1-c1ccccc1)C(=O)Nc1cccc(c1)C(F)(F)F)C(=O)C1CCN(CC1)C(C)=O

CN(CCCn1c(C)c(cc1-c1ccccc1)C(=O)Nc1cccc(c1)C(F)(F)F)C(=O)c1ccc2occc2c1

CN(CCCn1c(C)c(cc1-c1ccccc1)C(=O)Nc1cccc(c1)C(F)(F)F)C(=O)C1CCC1

CN(C)c1ccc(cc1)C(=O)N(C)CCCn1c(C)c(cc1-c1ccccc1)C(=O)Nc1cccc(c1)C(F)(F)F

CN(CCCn1c(C)c(cc1-c1ccccc1)C(=O)Nc1cccc(c1)C(F)(F)F)C(=O)c1csc(n1)-c1ccccc1

CN(CCCn1c(C)c(cc1-c1ccccc1)C(=O)Nc1cccc(c1)C(F)(F)F)C(=O)c1csc(n1)-c1cccs1

CN(CCCn1c(C)c(cc1-c1ccccc1)C(=O)Nc1cccc(c1)C(F)(F)F)C(=O)C(Cl)(Cl)Cl

COc1ccc(OC)c(CC(=O)N(C)CCCn2c(C)c(cc2-c2ccccc2)C(=O)Nc2cccc(c2)C(F)(F)F)c1

CN(CCCn1c(C)c(cc1-c1ccccc1)C(=O)Nc1cccc(c1)C(F)(F)F)C(=O)c1cnc2ccccc2n1

CN(CCCn1c(C)c(cc1-c1ccccc1)C(=O)Nc1cccc(c1)C(F)(F)F)C(=O)C(=O)c1c[nH]c2ccccc12

CN(CCCn1c(C)c(cc1-c1ccccc1)C(=O)Nc1cccc(c1)C(F)(F)F)C(=O)C1CCOCC1

CN(C)c1cccc(c1)C(=O)N(C)CCCn1c(C)c(cc1-c1ccccc1)C(=O)Nc1cccc(c1)C(F)(F)F

Cc1c(NC(=O)c2cccc(c2)C(F)(F)F)cc(-c2ccccc2)n1CCCN1CCOCC1

OC[C@]1(O)CN(C[C@@H]1Cc1ccc(C#N)c(F)c1)S(=O)(=O)c1ccc(Cl)cc1Cl |r|

OC[C@]1(O)CN(C[C@@H]1Cc1ccc(cc1)C#N)S(=O)(=O)c1ccc(cc1Cl)C(F)(F)F |r|

OC[C@]1(O)CN(C[C@@H]1Cc1ccc(cc1OCC(F)(F)F)C#N)S(=O)(=O)c1ccc(Cl)cn1 |r|

OC[C@@]1(O)CN(C[C@@H]1Cc1ccc(C#N)c(F)c1)S(=O)(=O)c1ccc(Cl)cc1Cl |r|

OC[C@]1(O)CN(C[C@@H]1Cc1ccc(C#N)c(F)c1)S(=O)(=O)c1ccc(cc1C#N)C(F)(F)F |r|

OC[C@]1(O)CN(C[C@@H]1Cc1ccc(C#N)c(F)c1)S(=O)(=O)c1ccc(cc1Cl)C#N |r|

NC[C@]1(O)CN(C[C@@H]1Cc1ccc(C#N)c(F)c1)S(=O)(=O)c1ccc(Cl)cn1 |r|

CCC(=O)c1sc(nc1[O-])-c1cccc(F)c1

OC[C@]1(O)CN(C[C@@H]1S(=O)(=O)c1ccc(Cl)cn1)S(=O)(=O)c1ccc(cc1Cl)C#N |r|

OC[C@]1(O)CN(C[C@@H]1S(=O)(=O)c1ccc(Cl)cc1)S(=O)(=O)c1ccc(cc1Cl)C#N |r|

OC[C@@]1(O)CN(C[C@@H]1S(=O)(=O)c1ccc(C#N)c(F)c1)S(=O)(=O)c1ccc(cc1Cl)C#N |r|

OC[C@@]1(O)CN(C[C@@H]1S(=O)(=O)c1ccc(C#N)c(F)c1)S(=O)(=O)c1ccccc1Cl |r|

Fc1cc(S)cc(F)c1C#N

Fc1cc(S)ccc1C#N

Fc1cc(C#N)c(F)cc1S

Sc1ccc(C#N)c(Cl)c1

FC(F)(F)c1ccc(S)cn1

OC[C@]1(O)CN(C[C@@H]1S(=O)(=O)c1ccc(C#N)c(F)c1)S(=O)(=O)c1ccc(cc1Cl)C#N |r|

OC[C@]1(O)CN(C[C@@H]1S(=O)(=O)c1ccc(C#N)c(F)c1)S(=O)(=O)c1ccccc1Cl |r|

OC[C@]1(O)CN(C[C@@H]1S(=O)(=O)c1ccc(C#N)c(F)c1)S(=O)(=O)c1ccc(F)cc1Cl |r|

Cc1ccc(c(Cl)c1)S(=O)(=O)N1C[C@@H]([C@](O)(CO)C1)S(=O)(=O)c1ccc(C#N)c(F)c1 |r|

FC(F)c1ccc(c(Cl)c1)S(Cl)(=O)=O

FC(F)Oc1ncccc1S(Cl)(=O)=O

COc1cc(Cl)ccc1S(Cl)(=O)=O

OC[C@]1(O)CN(C[C@@H]1S(=O)(=O)c1ccc(Cl)cc1)S(=O)(=O)c1ccc(Cl)cc1C#N |r|

FC(F)(F)c1cc(ccc1S(Cl)(=O)=O)C#N

OC[C@]1(O)CN(C[C@@H]1S(=O)(=O)c1ccc(Cl)cc1)S(=O)(=O)c1ccc(cc1C(F)(F)F)C#N |r|

CCOc1cc(ccc1S(Cl)(=O)=O)C#N

OC[C@]1(O)CN(C[C@@H]1S(=O)(=O)c1ccc(Cl)cc1)S(=O)(=O)c1ccc(cc1F)C#N |r|

OC[C@@]1(O)CN(C[C@@H]1S(=O)(=O)c1ccc(Cl)cc1)S(=O)(=O)c1ccc(cc1Cl)C#N |r|

OC[C@@]1(O)CN(C[C@@H]1S(=O)(=O)c1ccc(Br)cc1)S(=O)(=O)c1ccc(cc1Cl)C#N |r|

OC[C@]1(O)CN(C[C@@H]1S(=O)(=O)c1ccc(cc1)C#N)S(=O)(=O)c1ccc(Cl)cc1C(F)(F)F |r|

OC[C@]1(O)CN(C[C@@H]1S(=O)(=O)c1ccc(nc1)C(F)(F)F)S(=O)(=O)c1ccc(cc1Cl)C#N |r|

OC[C@]1(O)CN(C[C@@H]1S(=O)(=O)c1ccc(nc1)C(F)(F)F)S(=O)(=O)c1ccc(cc1C(F)(F)F)C#N |r|

Cc1cc(ccc1S(=O)(=O)N1C[C@@H]([C@](O)(CO)C1)S(=O)(=O)c1ccc(cc1)C#N)C(F)(F)F |r|

OC[C@]1(O)CN(C[C@@H]1S(=O)(=O)c1ccc(cc1)C#N)S(=O)(=O)c1ccc(F)cc1C(F)(F)F |r|

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OC[C@]1(O)CN(C[C@@H]1S(=O)(=O)c1ccc(cc1)C#N)S(=O)(=O)c1ccc(cc1Cl)C(F)F |r|

Cc1ccc(c(Cl)c1)S(=O)(=O)N1C[C@@H]([C@](O)(CO)C1)S(=O)(=O)c1ccc(cc1)C#N |r|

OC[C@]1(O)CN(C[C@@H]1S(=O)(=O)c1ccc(cc1)C#N)S(=O)(=O)c1ccc(cc1Cl)C#N |r|

CCc1cc(ccc1S(=O)(=O)N1C[C@@H]([C@](O)(CO)C1)S(=O)(=O)c1ccc(Cl)cc1)C#N |r|

OC[C@]1(O)CN(C[C@@H]1S(=O)(=O)c1ccc(Cl)cc1)S(=O)(=O)c1ccccc1C#N |r|

OC[C@]1(O)CN(C[C@@H]1S(=O)(=O)c1ccc(Cl)cc1)S(=O)(=O)c1ccc(cc1C(F)F)C#N |r|

CCOc1cc(ccc1S(=O)(=O)N1C[C@@H]([C@](O)(CO)C1)S(=O)(=O)c1ccc(Cl)cc1)C#N |r|

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COc1cc(Cl)ccc1S(=O)(=O)N1C[C@@H]([C@](O)(CO)C1)S(=O)(=O)c1ccc(cc1)C#N |r|

COc1cc(Br)ccc1S(=O)(=O)N1C[C@@H]([C@](O)(CO)C1)S(=O)(=O)c1ccc(cc1)C#N |r|

OC[C@]1(O)CN(C[C@@H]1S(=O)(=O)c1ccc(cc1)C(F)(F)F)S(=O)(=O)c1ccccc1C#N |r|

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OC[C@]1(O)CN(C[C@@H]1S(=O)(=O)c1ccc(cc1)C#N)S(=O)(=O)c1ccc(Cl)cc1Br |r|

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OCC(=O)c1ccc(cc1)S(=O)(=O)[C@H]1CN(C[C@@]1(O)CO)S(=O)(=O)c1ccc(Cl)cc1C(F)F |r|

OC[C@]1(O)CN(C[C@@H]1S(=O)(=O)c1ccc(Cl)cc1)S(=O)(=O)c1ccc(Cl)cc1C(F)F |r|

OC[C@]1(O)CN(C[C@@H]1S(=O)(=O)c1ccc(Cl)cc1)S(=O)(=O)c1ccc(Cl)cc1CC#N |r|

OC[C@]1(O)CN(C[C@@H]1S(=O)(=O)c1ccc(Cl)cc1)S(=O)(=O)c1cccnc1 |r|

OC[C@]1(O)CN(C[C@@H]1S(=O)(=O)c1nccs1)S(=O)(=O)c1ccc(cc1Cl)C#N |r|

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OC[C@]1(O)CN(C[C@@H]1S(=O)(=O)c1ccc(Br)cc1)S(=O)(=O)c1ccc(cc1Cl)C#N |r|

OC[C@@]1(O)CN(C[C@@H]1S(=O)(=O)c1ccc(C#N)c(F)c1)S(=O)(=O)c1ccc(Cl)cc1Cl |r|

OC[C@@]1(O)CN(C[C@@H]1S(=O)(=O)c1ccc(Cl)c(F)c1)S(=O)(=O)c1ccc(Cl)cc1Cl |r|

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OC[C@]1(O)CN(C[C@@H]1S(=O)(=O)c1ccc(cc1)C#N)S(=O)(=O)c1ccc(Cl)cc1Cl |r|

OC[C@]1(O)CN(C[C@@H]1S(=O)(=O)c1ccc(C#N)c(F)c1)S(=O)(=O)c1ccc(Cl)cc1Cl |r|

OC[C@]1(O)CN(C[C@@H]1S(=O)(=O)c1ccc(cc1)C#N)S(=O)(=O)c1ccc(Cl)cc1C#N |r|

OC[C@]1(O)CN(C[C@@H]1S(=O)(=O)c1ccc(F)c(F)c1)S(=O)(=O)c1ccc(Cl)cc1Cl |r|

OC[C@]1(O)CN(C[C@@H]1S(=O)(=O)c1ccc(cc1F)C#N)S(=O)(=O)c1ccc(Cl)cc1Cl |r|

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C[C@H](O)[C@]1(O)CN(C[C@@H]1S(=O)(=O)c1ccc(Cl)cn1)S(=O)(=O)c1ccc(cc1Cl)C#N |r|

C[C@@H](O)[C@]1(O)CN(C[C@@H]1S(=O)(=O)c1ccc(Cl)cn1)S(=O)(=O)c1ccc(cc1Cl)C#N |r|

NC[C@]1(O)CN(C[C@@H]1S(=O)(=O)c1ccc(Cl)cn1)S(=O)(=O)c1ccc(cc1Cl)C#N |r|

NC[C@@]1(O)CN(C[C@@H]1S(=O)(=O)c1ccc(Cl)cc1)S(=O)(=O)c1ccc(cc1Cl)C#N |r|

NC[C@]1(O)CN(C[C@@H]1S(=O)(=O)c1ccc(Cl)cc1)S(=O)(=O)c1ccc(cc1Cl)C#N |r|

CNC[C@]1(O)CN(C[C@@H]1S(=O)(=O)c1ccc(Cl)cc1)S(=O)(=O)c1ccc(cc1Cl)C#N |r|

NC[C@@]1(O)CN(C[C@@H]1S(=O)(=O)c1ccc(Cl)cn1)S(=O)(=O)c1ccc(cc1Cl)C#N |r|

NC[C@]1(O)CN(C[C@@H]1S(=O)(=O)c1ccc(Cl)cc1)S(=O)(=O)c1ccc(cc1)C#N |r|

NC[C@@]1(O)CN(C[C@@H]1S(=O)(=O)c1ccc(Cl)cc1)S(=O)(=O)c1ccc(cc1)C#N |r|

O[C@]1(CNCC(F)(F)F)CN(C[C@@H]1S(=O)(=O)c1ccc(Cl)cc1)S(=O)(=O)c1ccc(cc1Cl)C#N |r|

Clc1ccc(nc1)S(=O)(=O)[C@H]1CN(C[C@]11CNCCO1)S(=O)(=O)c1ccc(cc1Cl)C#N |r|

COc1ccc(CN2C[C@@]3(CCC[C@](CC#N)(Cn4cnc5ccc(cc45)C#N)C3)OC2=O)cc1 |r|

C[C@]1(Cn2cnc3ccc(cc23)C#N)CCC[C@@]2(CN(Cc3ccccc3F)C(=O)O2)C1 |r|

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OC(=O)c1ccc(cc1)S(=O)(=O)N(Cc1ccc(OC(F)(F)F)cc1)c1ncc(cc1Cl)C(F)(F)F

COc1ccc(cc1)S(=O)(=O)Nc1c(C)cc(C)cc1C

CC(C)N1CCN(CC1)S(=O)(=O)c1ccc(NC(=O)c2ccc(cc2[N+]([O-])=O)C(F)(F)F)cc1

CC(C)N1CCN(CC1)S(=O)(=O)c1ccc(NC(=O)c2ccc(cc2N)C(F)(F)F)cc1

CC(C)N1CCN(CC1)S(=O)(=O)c1ccc(NC(=O)c2ccc(cc2C(F)(F)F)C(F)(F)F)cc1

CC(C)N1CCN(CC1)S(=O)(=O)c1ccc(NC(=O)c2ccc(cc2F)C(F)(F)F)cc1

CC(C)N1CCN(CC1)S(=O)(=O)c1ccc(NC(=O)c2ccc(cc2)S(F)(F)(F)(F)F)cc1

CN(C)S(=O)(=O)c1ccc(NC(=O)c2ccc(cc2)C(F)(F)F)cc1

CC(C)N1CCN(CC1)C(=O)c1ccc(NC(=O)c2ccc(cc2)C(F)(F)F)cc1

CC(C)N1CCN(CC1)S(=O)(=O)c1ccc(NS(=O)(=O)c2ccc(cc2)C(F)(F)F)cc1

CC(C)N1CCN(CC1)S(=O)(=O)c1ccc(NC(=O)c2cccc(c2)C(F)(F)F)cc1

CC(C)N1CCN(CC1)S(=O)(=O)c1ccc(NC(=O)c2ccc(cc2)C(F)(F)F)cc1

CC(C)N1CCN(CC1)S(=O)(=O)c1ccc(NC(=O)c2ccc(cc2)C(C)(C)C)cc1

CC(C)N1CCN(CC1)S(=O)(=O)c1ccc(NC(=O)c2ccc(cc2)-c2ncccc2Cl)cc1

CC(C)N1CCN(CC1)S(=O)(=O)c1ccc(NC(=O)c2ccc(cc2)-c2ccccn2)cc1

CC(C)N1CCN(CC1)S(=O)(=O)c1ccc(NC(=O)c2ccccc2)cc1

FC(F)(F)c1ccc(cc1)C(=O)Nc1ccc(cc1)S(=O)(=O)N1CCN(CC1)C1CCCC1

CCN(C)C1CCN(CC1)S(=O)(=O)c1ccc(NC(=O)c2ccc(cc2)C(F)(F)F)cc1

CCN(CC)C1CCN(CC1)S(=O)(=O)c1ccc(NC(=O)c2ccc(cc2)C(F)(F)F)cc1

CN(C)C1CCN(CC1)S(=O)(=O)c1ccc(NC(=O)c2ccc(cc2)C(F)(F)F)cc1

CC(C)N1CCCN(CC1)S(=O)(=O)c1ccc(NC(=O)c2ccc(cc2)C(F)(F)F)cc1

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Cc1nc(C)c(s1)-c1csc(Nc2ccc(cn2)C(=O)N2[C@H]3CC[C@@H]2C[C@H](N)C3)n1 |r|

[H][C@]12CC[C@]([H])(C\C(C1)=N/OCCO)N2C(=O)c1ccc(Nc2nc(cs2)-c2sc(C)nc2C)nc1 |r|

CC(=O)N1CC2CCC(C1)N2C(=O)c1ccc(Nc2nc(cs2)-c2sc(C)nc2C)nc1

Cc1nc(C)c(s1)-c1csc(Nc2ccc(cn2)C(=O)N2C3CCC2CN(C3)c2ccc(Cl)cc2)n1

Cc1nc(C)c(s1)-c1csc(Nc2ccc(cn2)C(=O)N2[C@H]3CC[C@@H]2C[C@@H](C3)OC(=O)NCCF)n1 |r|

Cc1nc(C)c(s1)-c1csc(Nc2ccc(cn2)C(=O)N2C3CNCC2COC3)n1

[H][C@]12CC[C@]([H])(C\C(C1)=N/OC[C@@H](O)C(F)(F)F)N2C(=O)c1ccc(Nc2nc(cs2)-c2sc(C)nc2C)nc1 |r|

Cc1nc(C)c(s1)-c1csc(Nc2ccc(cn2)C(=O)N2[C@H]3CC[C@@H]2C[C@H](CO)C3)n1 |r|

COC(=O)N1CC2CCCC(C1)N2C(=O)c1ccc(Nc2nc(cs2)-c2sc(C)nc2C)nc1

Cc1nc(C)c(s1)-c1csc(Nc2ccc(cn2)C(=O)N2C3CCC2CC(=O)C3)n1

CO[C@@H]1C[C@@H]2CC[C@H](C1)N2C(=O)c1ccc(Nc2nc(cs2)-c2sc(C)nc2C)nc1 |r|

COC(=O)N1CCN(C(C1)C(F)(F)F)C(=O)c1ccc(Nc2nc(cs2)-c2sc(C)nc2C)nc1

Cc1nc(C)c(s1)-c1csc(Nc2ccc(cn2)C(=O)N2C3CCC2CNC3)n1

COC(=O)N1CCN(CC1)C(=O)c1ccc(Nc2nc(cs2)-c2sc(C)nc2C)nc1

[H][C@]12CC[C@]([H])(C\C(C1)=N/OCC(F)(F)F)N2C(=O)c1ccc(Nc2nc(cs2)-c2sc(C)nc2C)nc1 |r|

[H][C@]12CC[C@]([H])(C\C(C1)=N/OC)N2C(=O)c1ccc(Nc2nc(cs2)-c2sc(C)nc2C)nc1 |r|

Cc1nc(C)c(s1)-c1csc(Nc2ccc(cn2)C(=O)N2C3CCC2CN(C3)c2ncc(cn2)C(F)(F)F)n1

[H][C@]12CC[C@]([H])(C\C(C1)=N/OCC(N)=O)N2C(=O)c1ccc(Nc2nc(cs2)-c2sc(C)nc2C)nc1 |r|

Cc1nc(C)c(s1)-c1csc(Nc2ccc(cn2)C(=O)N2C3CCC2CN(C3)c2ncc(Cl)cn2)n1

Cc1nc(C)c(s1)-c1csc(Nc2ccc(cn2)C(=O)N2[C@H]3CC[C@@H]2C[C@@H](O)C3)n1 |r|

Cc1nc(C)c(s1)-c1csc(Nc2ccc(cn2)C(=O)N2[C@H]3CC[C@@H]2C[C@@H](C3)OCCO)n1 |r|

CC(=O)N[C@@H]1C[C@@H]2CC[C@H](C1)N2C(=O)c1ccc(Nc2nc(cs2)-c2sc(C)nc2C)nc1 |r|

Cc1nc(C)c(s1)-c1csc(Nc2ccc(cn2)C(=O)N2[C@H]3CC[C@@H]2C[C@@H](C3)NC(=O)CC(F)(F)F)n1 |r|

[H][C@]12CC[C@]([H])(CC(C1)=NOCC(C)(C)O)N2C(=O)c1ccc(Nc2nc(cs2)-c2sc(C)nc2C)nc1 |r|

COC(=O)N1CC2CCC(C1)N2C(=O)c1ccc(Nc2nc(cs2)-c2sc(C)nc2C)nc1

CNC(=O)N1CC2CCC(C1)N2C(=O)c1ccc(Nc2nc(cs2)-c2sc(C)nc2C)nc1

Cc1nc(C)c(s1)-c1csc(Nc2ccc(cn2)C(=O)N2C3CCC2CN(C3)C2CCCCC2)n1

Cc1nc(C)c(s1)-c1csc(Nc2ccc(cn2)C(=O)N2C3CCC2CN(C3)c2ccc(Cl)cn2)n1

Cc1c(cc(-c2ccccc2)n1CCCN1CCOCC1)C(=O)Nc1cccc(c1)C(F)(F)F

[H][C@]12CC[C@]([H])(C\C(C1)=N/OCCCO)N2C(=O)c1ccc(Nc2nc(cs2)-c2sc(C)nc2C)nc1 |r|

Cc1nc(C)c(s1)-c1csc(Nc2ccc(cn2)C(=O)N2C3COCC2CC(=O)C3)n1

Cc1nc(C)c(s1)-c1csc(Nc2ccc(cn2)C(=O)N2[C@H]3CC[C@@H]2C[C@@H](C3)Oc2ncc(cn2)C(F)(F)F)n1 |r|

[H][C@]12CC[C@]([H])(C\C(C1)=N/O)N2C(=O)c1ccc(Nc2nc(cs2)-c2sc(C)nc2C)nc1 |r|

Cc1nc(C)c(s1)-c1csc(Nc2ccc(cn2)C(=O)N2C3CCC2CN(CC(F)(F)F)C3)n1

CCNC(=O)O[C@@H]1C[C@@H]2CC[C@H](C1)N2C(=O)c1ccc(Nc2nc(cs2)-c2sc(C)nc2C)nc1 |r|

[H][C@]12CC[C@]([H])(C\C(C1)=N/OC1CCN(C)CC1)N2C(=O)c1ccc(Nc2nc(cs2)-c2sc(C)nc2C)nc1 |r|

CC1CC(=O)CC(C)N1C(=O)c1ccc(Nc2nc(cs2)-c2sc(C)nc2C)nc1

Cc1nc(C)c(s1)-c1csc(Nc2ccc(cn2)S(=O)(=O)Nc2ccc(Cl)cc2)n1

Cc1nc(C)c(s1)-c1csc(Nc2cccc(n2)C#N)n1

Cc1nc(C)c(s1)-c1csc(Nc2ccccn2)n1

Cc1nc(C)c(s1)-c1csc(Nc2ccc(NS(=O)(=O)c3ccc(Cl)cc3)cn2)n1

Cc1nc(C)c(s1)-c1csc(Nc2ccc(NC(=O)c3ccc(Cl)cc3)cn2)n1

Cc1nc(C)c(s1)-c1csc(Nc2ncccn2)n1

Cc1nc(C)c(s1)-c1csc(Nc2ccc(cn2)C(=O)N2CCC(=O)CC2)n1

Cc1nc(C)c(s1)-c1csc(Nc2cccnc2)n1

CC1CCCC(C)N1C(=O)c1ccc(Nc2nc(cs2)-c2sc(C)nc2C)nc1

Cc1nc(C)c(s1)-c1csc(Nc2ccc(cn2)C(=O)NC2CCCCC2)n1

Cc1nc(C)c(s1)-c1csc(Nc2ccc(cn2)C(=O)NCc2ccc(Cl)cc2)n1

Cc1nc(C)c(s1)-c1csc(Nc2ccc(cn2)C(=O)Nc2ccc(Cl)cc2)n1

CCOC(=O)c1ccc(Nc2nc(cs2)-c2sc(C)nc2C)nc1

Cc1nc(C)c(s1)-c1csc(Nc2ncccc2C#N)n1

COc1ccc(Nc2nc(cs2)-c2sc(C)nc2C)nc1

COc1ccnc(Nc2nc(cs2)-c2sc(C)nc2C)c1

Cc1nc(C)c(s1)-c1csc(Nc2ccncc2)n1

Cc1nc(C)c(s1)-c1csc(Nc2ccc(cn2)C(O)=O)n1

Cc1nc(C)c(s1)-c1csc(Nc2ccccc2)n1

COc1cccnc1Nc1nc(cs1)-c1sc(C)nc1C

CN(C(=O)c1ccc(Nc2nc(cs2)-c2sc(C)nc2C)nc1)c1ccc(Cl)cc1

Cc1nc(C)c(s1)-c1csc(Nc2ccc(cn2)C(=O)N2CCCCC2)n1

CCNC(=O)c1ccc(Nc2nc(cs2)-c2sc(C)nc2C)nc1

Cc1nc(C)c(s1)-c1csc(Nc2ccc(cn2)C#N)n1

COc1cccc(Nc2nc(cs2)-c2sc(C)nc2C)n1

Cc1nc(C)c(s1)-c1csc(Nc2ccc(Br)cc2)n1

Cc1nc(C)c(s1)-c1csc(Nc2cc(ccn2)C#N)n1

C[C@@H](N([C@@H](C(N)=O)c1ccccc1)C(=O)c1ccccc1)c1cc(F)cc(F)c1 |r|

CC(=O)Nc1cccc(Nc2ncnc(n2)N2CCC(CC2)OCc2ccc(OC(F)(F)F)cc2)c1C

C[C@@H](NC(=O)c1c(CN2CCC(CC2)N2CCCCC2)c(nc2ccccc12)-c1ccccc1)c1ccccc1 |r|

COc1cccc(c1)-c1nc2ccccc2c(C(=O)N[C@@H](C)c2ccccc2)c1CN1CCC(CC1)N1CCCCC1 |r|

C[C@H](NC(=O)c1c(CN2CCC(CC2)N2CCCCC2)c(nc2ccccc12)-c1cccc(c1)C(F)(F)F)c1ccccc1 |r|

C[C@H](NC(=O)c1c(CN2CCC(CC2)N2CCCCC2)c(nc2ccccc12)-c1cccc(Cl)c1)c1ccccc1 |r|

COc1ccc(cc1)-c1nc2ccccc2c(C(=O)N[C@@H](C)c2ccccc2)c1CN1CCC(CC1)N1CCCCC1 |r|

C[C@H](NC(=O)c1c(CN2CCC(CC2)N2CCCCC2)c(nc2ccccc12)-c1ccc(cc1)C(F)(F)F)c1ccccc1 |r|

C[C@H](NC(=O)c1c(CN2CCC(CC2)N2CCCCC2)c(nc2ccccc12)-c1ccc(Cl)cc1)c1ccccc1 |r|

C[C@H](NC(=O)c1c(CN2CCC(CC2)N2CCCCC2)c(nc2ccccc12)-c1ccccc1)c1ccccc1 |r|

COc1ccc2c(C(=O)NC3(CC3)c3ccccc3)c(CN3CCC(CC3)N3CCCCC3)c(nc2c1)-c1cccc(c1)C(F)(F)F

FC(F)(F)c1cccc(c1)-c1nc2cc(Br)ccc2c(C(=O)NC2(CC2)c2ccccc2)c1CN1CCC(CC1)N1CCCCC1

COc1ccc2c(C(=O)N[C@H](c3ccccc3)C(F)(F)F)c(CN3CCC(CC3)N3CCCCC3)c(nc2c1)-c1cccc(c1)C(F)(F)F |r|

FC(F)(F)[C@H](NC(=O)c1c(CN2CCC(CC2)N2CCCCC2)c(nc2cc(Br)ccc12)-c1cccc(c1)C(F)(F)F)c1ccccc1 |r|

FC(F)(F)[C@H](NC(=O)c1c(CN2CCC(CC2)N2CCCCC2)c(nc2ccc(Br)cc12)-c1cccc(c1)C(F)(F)F)c1ccccc1 |r|

CC(C)(NC(=O)c1c(CN2CCC(CC2)N2CCCCC2)c(nc2ccccc12)-c1cccc(c1)C(F)(F)F)c1ccccc1

FC(F)(F)[C@@H](NC(=O)c1c(CN2CCC(CC2)N2CCCCC2)c(nc2ccccc12)-c1cccc(c1)C(F)(F)F)c1ccccc1 |r|

FC(F)(F)[C@H](NC(=O)c1c(CN2CCC(CC2)N2CCCCC2)c(nc2ccccc12)-c1cccc(c1)C(F)(F)F)c1ccccc1 |r|

CC[C@H](NC(=O)c1c(CN2CCC(CC2)N2CCCCC2)c(nc2ccccc12)-c1cccc(c1)C(F)(F)F)c1ccccc1 |r|

FC(F)(F)c1cccc(c1)-c1nc2ccccc2c(C(=O)NCc2ccccc2)c1CN1CCC(CC1)N1CCCCC1

C[C@H](NC(=O)c1c(CN2CCC(CC2)C2CCCCC2)c(nc2ccccc12)-c1cccc(c1)C(F)(F)F)c1ccccc1 |r|

C[C@H](NC(=O)c1c(CN2CCC(CC2)N(C)C)c(nc2ccccc12)-c1cccc(c1)C(F)(F)F)c1ccccc1 |r|

C[C@H](NC(=O)c1c(CN2CCC(CC2)N2CCOCC2)c(nc2ccccc12)-c1cccc(c1)C(F)(F)F)c1ccccc1 |r|

C[C@@H](NC(=O)c1c(CN2CCC(CC2)N2CCCCC2)c(nc2ccccc12)-c1cccc(c1)C(F)(F)F)c1ccccc1 |r|

C[C@H](NC(=O)c1c(CN2CCC(CC2)N2CCCCC2)c(nc2ccccc12)-c1cccc(C)c1)c1ccccc1 |r|

C[C@H](NC(=O)c1c(CN2CCC(CC2)N2CCCCC2)c(nc2ccccc12)-c1ccc(C)cc1)c1ccccc1 |r|

CC(C)NCCN(C(C)C)S(=O)(=O)c1ccc(Cl)cc1Cl

FC(F)(F)c1cccc(c1)-c1nc2ccccc2c(C(=O)NC2(CC2)c2ccccc2)c1CN1CCC(CC1)N1CCCCC1

C[C@H](NC(=O)c1c(CN2CCCCC2)c(nc2ccccc12)-c1cccc(c1)C(F)(F)F)c1ccccc1 |r|

CCOc1ccc2c(C(=O)NC3(CC3)c3ccccc3)c(CN3CCC(CC3)N3CCCCC3)c(nc2c1)-c1cccc(c1)C(F)(F)F

CCOc1ccc2c(C(=O)N[C@H](c3ccccc3)C(F)(F)F)c(CN3CCC(CC3)N3CCCCC3)c(nc2c1)-c1cccc(c1)C(F)(F)F |r|

CC(C)[C@H](NC(=O)c1c(CN2CCC(CC2)N2CCCCC2)c(nc2ccccc12)-c1cccc(c1)C(F)(F)F)c1ccccc1 |r|

C[C@H](NC(=O)c1c(CN2CCC(CC2)N2CCNCC2)c(nc2ccccc12)-c1cccc(c1)C(F)(F)F)c1ccccc1 |r|

CCCCCC(=O)O[C@@H]1[C@@H](C)[C@]2(O)[C@@H]3C=C(C)C(=O)[C@]3(O)CC(CO)=C[C@H]2[C@@H]2C(C)(C)[C@]12OC(=O)CCCCC |r,c:25,t:14|

CCCCCCCCCC(=O)O[C@@H]1[C@@H](C)[C@@]2(O)[C@H]([C@@H]3C(C)(C)[C@]13OC(=O)CCCCCCCCC)C1C3[C@@H]2[C@H]2CC1(CO)C3(C)C2=O |r,THB:46:45:39.40:37.36|

CCCCCCCCCC(=O)O[C@@H]1[C@H]([C@]2([C@@H](C=C(C[C@@]3([C@H]2C=C(C3=O)C)O)CO)[C@H]4C1(C4(C)C)OC(=O)CCCCCCCCC)O)C

CCCCCCCCCC(=O)O[C@]12[C@H]([C@@H]3C=C(CO)C[C@]4(O)[C@@H](C=C(C)C4=O)[C@@]3(O)[C@H](C)[C@H]1O)C2(C)C |r,t:15,23|

CCCCCCCCCCCCCC(=O)O[C@@H]1[C@@H](C)[C@]2(O)[C@@H]3C=C(C)C(=O)[C@]3(O)CC(CO)=C[C@H]2[C@@H]2C(C)(C)[C@]12OC(=O)CCCCCCCCCCCCC |r,c:33,t:22|

CCCC(=O)O[C@@H]1[C@H]([C@]2([C@@H](C=C(C[C@]3([C@H]2C=C(C3=O)C)O)CO)[C@H]4[C@@]1(C4(C)C)OC(=O)CCC)O)C

C[C@@H]1[C@@H](OC(C)=O)[C@]2(OC(C)=O)[C@H]([C@@H]3C=C(CO)C[C@]4(O)[C@@H](C=C(C)C4=O)[C@@]13O)C2(C)C |r,t:14,22|

CCCCCCCC(=O)O[C@@H]1[C@@H](C)[C@]2(O)[C@@H]3C=C(C)C(=O)[C@]3(O)CC(CO)=C[C@H]2[C@@H]2C(C)(C)[C@]12OC(=O)CCCCCCC |r,c:27,t:16|

CCCCCCCCC(=O)O[C@@H]1[C@@H](C)[C@]2(O)[C@@H]3C=C(C)C(=O)[C@]3(O)CC(CO)=C[C@H]2[C@@H]2C(C)(C)[C@]12OC(=O)CCCCCCCC |r,c:28,t:17|

CCCCCCCCCC(=O)O[C@@H]1[C@@H](C)[C@]2(O)[C@@H]3C=C(C)C(=O)[C@@H]3CC(CO)=C[C@H]2[C@@H]2C(C)(C)[C@]12OC(=O)CCCCCCCCC |r,c:28,t:18|

Cc1nc(C)c(s1)-c1csc(Nc2ccc(cn2)C(=O)N2C3CCC2CN(C3)c2cnc(nc2)C(F)(F)F)n1

CC1(CCc2c1c(cc(c2)NC(=O)[C@H]3c4ccc(nc4CCN3C(=O)CCCC(=O)O)OC)F)C

Cc1cc(-c2csc(Nc3ccc(cn3)C(=O)N3C4CCC3CN(C4)c3ncc(cn3)C(F)(F)F)n2)n(C)n1

CC(O)c1nc(C)c(s1)-c1csc(Nc2ccc(cn2)C(=O)N2C3CCC2CN(C3)c2ncc(cn2)C(F)(F)F)n1

C[C@H]1CN(CCN1C(=O)c1ccc(Nc2nc(cs2)-c2sc(C)nc2C)nc1)c1ncc(cn1)C(F)(F)F |r|

C[C@@H]1CN(CCN1C(=O)c1ccc(Nc2nc(cs2)-c2sc(C)nc2C)nc1)c1ncc(cn1)C(F)(F)F |r|

Cc1nc(C)c(s1)-c1csc(Nc2ccc(cn2)C(=O)N2CCN(CC2C(F)(F)F)c2ncc(cn2)C(F)(F)F)n1

C[C@H]1CN(CCN1c1ncc(cn1)C(F)(F)F)C(=O)c1ccc(Nc2nc(cs2)-c2sc(C)nc2C)nc1 |r|

Cc1nc(C)c(s1)-c1csc(Nc2ccc(cn2)C(=O)N2CC3CCC(C2)N3c2ncc(cn2)C(F)(F)F)n1

Cc1nn(C)cc1-c1nsc(Nc2ccc(cn2)C(=O)N2C3CCC2CN(C3)c2ncc(cn2)C(F)(F)F)n1

Cc1nc(C)c(s1)-c1csc(Nc2ccc(cn2)C(=O)N2C3CCC2CN(C3)c2ccc(cc2)C(F)(F)F)n1

Cc1nc(C)c(s1)-c1csc(Nc2ccc(cn2)C(=O)N2C3CCC2CN(C3)c2ccc(cn2)C(F)(F)F)n1

Cc1nc(C)c(s1)-c1csc(Nc2ccc(cn2)C(=O)N2C3CCC2CN(C3)c2ccc(nn2)C(F)(F)F)n1

Cc1nc(C)c(s1)-c1csc(Nc2ccc(cn2)C(=O)N2C3CCC2CN(C3)c2ncccn2)n1

Cc1nc(C)c(s1)-c1csc(Nc2ccc(cn2)C(=O)N2C3CCC2CN(C3)c2ncc(Br)cn2)n1

Cc1nc(C)c(s1)-c1csc(Nc2ccc(cn2)C(=O)N2C3CCC2CN(C3)c2ncc(cn2)C#N)n1

Cc1nc(C)c(s1)-c1csc(Nc2ccc(cn2)C(=O)N2C3CCC2CN(C3)c2ncc(CO)cn2)n1

Cc1nc(C)c(s1)-c1csc(Nc2ccc(cn2)C(=O)N2C3CCC2CN(C3)c2ncc(cn2)C(O)=O)n1

Cc1nc(C)c(s1)-c1csc(Nc2ccc(cn2)C(=O)N2CCN(CC2)c2ncc(cn2)C(F)(F)F)n1

Cc1nc(C)c(s1)-c1csc(Nc2ccc(cn2)C(=O)N2CCN(CC2CO)c2ncc(cn2)C(F)(F)F)n1

C[C@@H]1CN(CCN1c1ncc(cn1)C(F)(F)F)C(=O)c1ccc(Nc2nc(cs2)-c2sc(C)nc2C)nc1 |r|

Cc1nn(C)cc1-c1csc(Nc2ccc(cn2)C(=O)N2C3CCC2CN(C3)c2ncc(cn2)C(F)(F)F)n1

Cc1nc(C)c(s1)-c1csc(Nc2ccc(cn2)C(=O)N2C3CCC2CN(C3)c2cnc(cn2)C(F)(F)F)n1

Cc1nc(C)c(s1)-c1csc(Nc2ccc(cn2)C(=O)N2C3CCC2CN(C3)c2ncc(F)cn2)n1

Cc1nc(C)c(s1)-c1csc(Nc2ccc(cn2)C(=O)N2C3CCC2CN(C3)c2ncc(cn2)S(C)(=O)=O)n1

Cc1nc(C)c(s1)-c1csc(Nc2ccc(cn2)C(=O)N2C3CCC2CN(C3)c2ncc(cn2)C(N)=O)n1

Cc1nc(C)c(s1)-c1nsc(Nc2ccc(cn2)C(=O)N2C3CCC2CN(C3)c2ncc(cn2)C(F)(F)F)n1

CC(C)c1ccc(NC(=O)Cn2cnc3n(C)c(=O)n(C)c(=O)c23)cc1

Cc1nc(Nc2cccc3CC[C@@H](O)Cc23)oc1-c1ccc(cc1)C(F)(F)F |r|

CCCCCc1cc(O)c-2c(OC(C)(C)c3ccc(C)cc-23)c1

CCCc1cc(O)c-2c(OC(C)(C)c3ccc(C)cc-23)c1

CC(C)Nc1nc2c(C(=O)N(C)C)c(Cl)c(Cl)cc2n1C1CCN(CC1)c1ccc(cc1)C(C)(C)C#N

CC(C)Nc1nc2c(C(=O)N(C)C)c(Cl)c(Cl)cc2n1C1CCN(CC1)c1ccc(cc1)C1(CCOCC1)C#N

CC(C)Nc1nc2c(C(=O)N(C)C)c(Cl)c(Cl)cc2n1C1CCN(CC1)c1ccc(cc1)C(C)(C)C(O)=O

COC(=O)C(C)(C)c1ccc(cc1)N1CCC(CC1)n1c(NC(C)C)nc2c(C(=O)N(C)C)c(Cl)c(Cl)cc12

CC(C)Nc1nc2c(C(=O)N(C)C)c(Cl)c(Cl)cc2n1C1CCN(CC1)c1ccc(OC(C)C)cc1

CC(C)Nc1nc2c(C(=O)N(C)C)c(Cl)c(Cl)cc2n1C1CCN(CC1)c1ccc(cc1)C1CCCCC1

CC(C)Nc1nc2c(C(=O)N(C)C)c(Cl)c(Cl)cc2n1C1CCN(CC1)c1ccc(cc1)C(C)(C)C

CC(C)Nc1nc2c(C(=O)N(C)C)c(Cl)c(Cl)cc2n1C1CCN(CC1)c1ccc(C)cc1

CC(C)Nc1nc2c(C(=O)N(C)C)c(Cl)c(Cl)cc2n1C1CCN(CC1)c1cccc(C)c1

CC(C)Nc1nc2c(C(=O)N(C)C)c(Cl)c(Cl)cc2n1C1CCN(CC1)C(=O)c1ccc(cc1)C(C)(C)C

CC(C)Nc1nc2c(C(=O)N(C)C)c(Cl)c(Cl)cc2n1C1CCN(CC1)C(=O)Nc1ccccc1

CC(C)Nc1nc2c(C(=O)N(C)C)c(Cl)c(Cl)cc2n1C1CCN(CC1)c1ccccc1

CC(C)Nc1nc2c(C(=O)N(C)C)c(Cl)c(Cl)cc2n1CC1CCN(CC1)c1ccccc1

CC(C)Nc1nc2c(C(=O)N(C)C)c(Cl)c(Cl)cc2n1-c1ccc(cc1)N1CCCCC1

CC(C)Nc1nc2c(C(=O)N(C)C)c(Cl)c(Cl)cc2n1C1CCN(Cc2ccccc2)CC1

CC(C)Nc1nc2c(C(=O)N(C)C)c(Cl)c(Cl)cc2n1C1CCN(CC1)S(=O)(=O)c1ccc(Cl)cc1

Clc1ccc(c(Cl)c1)S(=O)(=O)N1CCN(Cc2ccccc2)CC1

C[C@H]1CCCN([C@H]1C)C(=O)c1nc(Nc2ccc(Cl)cc2F)sc1C |r|

CC1CCCN(C1C)C(=O)c1csc(Nc2ccc(C)cc2)n1

O[C@@H]1CN(C[C@@H]1Oc1ccc(C#N)c(F)c1)S(=O)(=O)c1ccc(Cl)cc1Cl |r|

OC[C@H]1CN(C[C@@H]1Oc1ccc(C#N)c(F)c1)S(=O)(=O)c1ccc(Cl)cc1Cl |r|

OC1(COc2ccc(C#N)c(F)c2)CCN(CC1)S(=O)(=O)c1ccc(Cl)cc1Cl

OC1(COc2ccc(C#N)c(F)c2)CN(C1)S(=O)(=O)c1ccc(Cl)cc1Cl

Fc1cc(OCC2CCN(CC2)S(=O)(=O)c2ccc(Cl)cc2Cl)ccc1C#N

OC[C@]1(O)CN(C[C@@H]1Oc1ccc(C#N)c(F)c1)S(=O)(=O)c1ccc(Cl)cc1Cl |r|

OC1(COc2ccc(C#N)c(F)c2)CCN(C1)S(=O)(=O)c1ccc(Cl)cc1Cl

O[C@@H]1CN(C[C@@H]1COc1ccc(C#N)c(F)c1)S(=O)(=O)c1ccc(Cl)cc1Cl |r|

O[C@@H]1CN(C[C@H]1COc1ccc(C#N)c(F)c1)S(=O)(=O)c1ccc(Cl)cc1Cl |r|

O[C@H]1CN(C[C@]1(O)COc1ccc(C#N)c(F)c1)S(=O)(=O)c1ccc(Cl)cc1Cl |r|

OC[C@@]1(O)CN(C[C@@H]1Oc1ccc(C#N)c(F)c1)S(=O)(=O)c1ccc(Cl)cc1Cl |r|

Fc1cc(OC2CCN(C2)S(=O)(=O)c2ccc(Cl)cc2Cl)ccc1C#N

OC[C@@H]1CN(C[C@@H]1Oc1ccc(C#N)c(F)c1)S(=O)(=O)c1ccc(Cl)cc1Cl |r|

O[C@H]1CN(C[C@@H]1Oc1ccc(C#N)c(F)c1)S(=O)(=O)c1ccc(Cl)cc1Cl |r|

OC[C@]1(O)CN(C[C@@H]1Oc1ccc(C#N)c(F)c1)S(=O)(=O)c1ccc(cc1C#N)C(F)(F)F |r|

CCCCCc1cc(O)c2CCC(C)(CCCC(C)(C)c3ccc(C)cc3)Oc2c1

[H][C@]12Cc3c(O)cc(CCCCC)cc3O[C@]1(C)CCCC2(C)C |r|

[H][C@]12Cc3c(O)cc(CCCCC)cc3O[C@@]1(C)CCCC2(C)C |r|

CCCCCc1cc2O[C@]3(Cc2c(O)c1)[C@@H](C)CCCC3(C)C |r|

[H][C@]12Cc3c(O)cc(CCCCC)cc3O[C@]1(C)CC[C@@H](I)C2(C)C |r|

CCCCCc1cc2O[C@]3(Cc2c(O)c1)[C@H](C)CCCC3(C)C |r|

OC(=O)c1ccc(nc1)C(=O)N[C@@H](c1ccc(OC(F)(F)F)c(F)c1)c1ncccc1F |r|

CC(C)(C)N1C[C@@]2(CCC[C@H](Cn3cnc4ccc(cc34)C#N)C2)OC1=O |r|

COc1ccccc1N1C[C@@]2(CCC[C@H](Cn3cnc4ccc(cc34)C#N)C2)OC1=O |r|

C[C@]1(Cn2cnc3ccc(cc23)C#N)CCC[C@@]2(CN(C(=O)O2)c2cnc(cn2)C2CC2)C1 |r|

CC(C)(C)CN1C[C@@]2(CCC[C@@H](C2)C(C)(C)n2cnc3ccc(cc23)C#N)OC1=O |r|

CC(C)(C)CN1C[C@@]2(CCC[C@](C)(Cn3cnc4ccc(cc34)C#N)C2)OC1=O |r|

Fc1ccc(cc1)N1C[C@@]2(CCC[C@H](Cn3cnc4ccc(cc34)C#N)C2)OC1=O |r|

CCOc1ccc(cc1)N1C[C@@]2(CCC[C@H](Cn3cnc4ccc(cc34)C#N)C2)OC1=O |r|

CCOc1cccc(c1)N1C[C@@]2(CCC[C@H](Cn3cnc4ccc(cc34)C#N)C2)OC1=O |r|

Clc1ccccc1N1C[C@@]2(CCC[C@H](Cn3cnc4ccc(cc34)C#N)C2)OC1=O |r|

Fc1ccccc1N1C[C@@]2(CCC[C@H](Cn3cnc4ccc(cc34)C#N)C2)OC1=O |r|

Cc1ccccc1N1C[C@@]2(CCC[C@H](Cn3cnc4ccc(cc34)C#N)C2)OC1=O |r|

COc1ccccc1N1C[C@@]2(CCC[C@](C)(Cn3cnc4ccc(cc34)C#N)C2)OC1=O |r|

CCOc1ccc(cn1)N1C[C@@]2(CCC[C@](C)(Cn3cnc4ccc(cc34)C#N)C2)OC1=O |r|

CCOc1cnc(cn1)N1C[C@@]2(CCC[C@](C)(Cn3cnc4ccc(cc34)C#N)C2)OC1=O |r|

COc1cnc(cn1)N1C[C@@]2(CCC[C@](C)(Cn3cnc4ccc(cc34)C#N)C2)OC1=O |r|

Cc1cnc(cn1)N1C[C@@]2(CCC[C@](C)(Cn3cnc4ccc(cc34)C#N)C2)OC1=O |r|

C[C@@]1(CCC[C@]2(C1)CN(C(=O)O2)c3cnc(cn3)C(C)(C)O)Cn4cnc5c4cc(cc5)C#N

C[C@]1(Cn2cnc3ccc(cc23)C#N)CCC[C@@]2(CNC(=O)O2)C1 |r|

C[C@]1(Cn2cnc3ccc(cc23)C#N)CCC[C@@]2(CN(C(=O)O2)c2ccccc2F)C1 |r|

Cc1ccccc1N1C[C@@]2(CCC[C@](C)(Cn3cnc4ccc(cc34)C#N)C2)OC1=O |r|

O=C1O[C@@]2(CN1c1ccccc1)CCC[C@H](Cn1cnc3ccc(cc13)C#N)C2 |r|

Clc1cccc(c1)N1C[C@@]2(CCC[C@H](Cn3cnc4ccc(cc34)C#N)C2)OC1=O |r|

CCOc1ccc(cc1)N1C[C@@]2(CCC[C@](C)(Cn3cnc4ccc(cc34)C#N)C2)OC1=O |r|

CCOc1ccc(nn1)N1C[C@@]2(CCC[C@](C)(Cn3cnc4ccc(cc34)C#N)C2)OC1=O |r|

CC(C)(C)c1cnc(cn1)N1C[C@@]2(CCC[C@](C)(Cn3cnc4ccc(cc34)C#N)C2)OC1=O |r|

CCOc1cccc(c1)N1C[C@@]2(CCC[C@](C)(Cn3cnc4ccc(cc34)C#N)C2)OC1=O |r|

CC(C)(C)CN1C[C@@]2(CCC[C@H](Cn3cnc4ccc(cc34)C#N)C2)OC1=O |r|

C[C@]1(Cn2cnc3ccc(cc23)C#N)CCC[C@@]2(CN(C(=O)O2)c2ccc(F)cc2)C1 |r|

C[C@]1(Cn2cnc3ccc(cc23)C#N)CCC[C@@]2(CN(C(=O)O2)c2cccc(Cl)c2)C1 |r|

C[C@]1(Cn2cnc3ccc(cc23)C#N)CCC[C@@]2(CN(C(=O)O2)c2ccccc2Cl)C1 |r|

OC[C@]1(O)CN(C[C@@H]1Oc1ccc(C#N)c(F)c1)S(=O)(=O)c1ccccc1C#N |r|

OC[C@]1(O)CN(C[C@@H]1Oc1ccc(C#N)c(F)c1)S(=O)(=O)c1ccc(Cl)cc1 |r|

OC[C@]1(O)CN(C[C@@H]1Oc1ccc(C#N)c(F)c1)S(=O)(=O)c1ccc(cc1)C(F)(F)F |r|

OC[C@]1(O)CN(C[C@@H]1Oc1ccc(C#N)c(F)c1)S(=O)(=O)c1ccc(Cl)cn1 |r|

OC[C@]1(O)CN(C[C@@H]1S(=O)(=O)c1ccc(cc1)C#N)S(=O)(=O)c1ccc(Cl)cn1 |r|

c1cc(c(cc1O[C@H]2CN(C[C@]2(CN)O)S(=O)(=O)c3ccc(cn3)Cl)F)C#N

NC[C@]1(O)CN(C[C@@H]1Oc1ccc(C#N)c(F)c1)S(=O)(=O)c1ccc(Cl)cc1Cl |r|

OC[C@]1(O)CN(C[C@@H]1Oc1ccc(C#N)c(F)c1)S(=O)(=O)c1ccc(nc1)C(F)(F)F |r|

OC[C@@]1(O)CN(C[C@@H]1Oc1ccc(C#N)c(F)c1)S(=O)(=O)c1ccc(Cl)cn1 |r|

c1ccc2c(c1)nc(n2Cc3ccc(cc3)Cl)CN4CCCC4

O[C@H]1CN(C[C@@H]1Oc1ccc(cc1)C#N)S(=O)(=O)c1ccc(Cl)cc1Cl |r|

CC(C)(C)c1cc(no1)N1C[C@@]2(CCC[C@](C)(Cn3cnc4ccc(cc34)C#N)C2)OC1=O |r|

OC[C@]1(O)CN(C[C@@H]1S(=O)(=O)c1ccc(Cl)cc1)S(=O)(=O)c1ccc(nc1C(F)(F)F)C#N |r|

OC[C@]1(O)CN(C[C@@H]1S(=N)(=O)c1ccc(Cl)cc1)S(=O)(=O)c1ccc(cc1Cl)C#N |r|

OC[C@]1(O)CN(C[C@@H]1S(=O)(=O)c1ccc(Cl)cc1)S(=N)(=O)c1ccc(cc1Cl)C#N |r|

OC[C@]1(O)CN(C[C@H]1S(=O)(=O)c1ccc(cc1)C#N)S(=O)(=O)c1ccc(Cl)cc1Cl |r|

OC[C@@]1(O)CN(C[C@@H]1S(=O)(=O)c1ccc(cc1)C#N)S(=O)(=O)c1ccc(Cl)cc1Cl |r|

O[C@H]1CN(C[C@@H]1S(=O)(=O)c1ccc(cc1)C#N)S(=O)(=O)c1ccc(Cl)cc1Cl |r|

OC[C@@]1(O)CN(C[C@H]1S(=O)(=O)c1ccc(cc1)C#N)S(=O)(=O)c1ccc(Cl)cc1Cl |r|

OC[C@]1(O)CN(C[C@@H]1S(=O)(=O)c1ccc(Cl)cc1)S(=O)(=O)c1ccc(nc1)C#N |r|

[H][C@]12C[C@@H](C)C[C@@H](C(O)=O)[C@]1([H])[C@](C)([C@@H](\C(C)=C\C)C(C)=C2)C(=O)c1cccnc1 |r,c:21|

CN1CCN(CC1)c1sc(NC(=O)c2cnn(c2C)-c2ccc(cc2)C#N)nc1C1CCC1

CN1CCN(CC1)c1sc(NC(=O)c2cnn(c2C)-c2ccccc2)nc1C1CCC1

Cc1c(cnn1-c1ccc(F)cn1)C(=O)Nc1nc(C2CCC2)c(CCN2CCCCC2)s1

Cc1c(cnn1-c1ccc(F)cc1)C(=O)Nc1nc(C2CCC2)c(CCN2CCCCC2)s1

COc1cc(OC)cc(c1)C(=O)Nc1nc(c(CN2CCCCC2)s1)-c1ccccc1

COc1cc(OC)cc(c1)C(=O)Nc1nc(c(CCCN2CCN(C)CC2)s1)-c1ccccc1

COc1cc(OC)cc(c1)C(=O)Nc1nc(c(CCCN2CCOCC2)s1)-c1ccccc1

COc1cc(OC)cc(c1)C(=O)Nc1nc(c(CCCN(C)C)s1)-c1ccccc1

CN1CCN(CC1)c1sc(NC(=O)c2cnn(Cc3ccc(F)cc3)c2C)nc1C1CCC1

CN1CCN(CC1)c1sc(NC(=O)c2cnn(C3CCC(F)(F)CC3)c2C)nc1C1CCC1

CN1CCN(CC1)c1sc(NC(=O)c2cnn(c2C)C(C)(C)C)nc1C1CCC1

CN1CCN(CC1)c1sc(NC(=O)c2oc(nc2C)-c2ccccc2)nc1C1CCC1

CN1CCN(CC1)c1sc(NC(=O)c2cc(-c3ccccc3)n(C)n2)nc1C1CCC1

CN1CCN(CC1)c1sc(NC(=O)c2cc(cs2)-c2ccccc2)nc1C1CCC1

COc1cc(OC)cc(c1)C(=O)Nc1nc(C2CCC2)c(s1)N1CCN(C)CC1

COc1cc(OC)cc(c1)C(=O)Nc1nc(C2CC2)c(s1)N1CCN(C)CC1

COc1cc(OC)cc(c1)C(=O)Nc1nc(c(s1)N1CCN(C)CC1)-c1ccccn1

COc1cc(OC)cc(c1)C(=O)Nc1nc(c(s1)N1CCN(C)CC1)-c1ccccc1

COc1cc(OC)cc(c1)C(=O)Nc1nc(c(CCCN2CCCCC2)s1)-c1ccccc1

CN1CCN(CC1)c1sc(NC(=O)c2cnn(C3CCCCC3)c2C)nc1C1CCC1

CN1CCN(CC1)c1sc(NC(=O)c2cnn(C)c2C)nc1C1CCC1

CN1CCN(CC1)c1sc(NC(=O)c2cnn(c2C)-c2ccc(F)cc2)nc1C1CCC1

COc1cc(OC)cc(c1)C(=O)Nc1nc(c(s1)N1CCN(C)CC1)-c1ccncc1

COc1cc(OC)cc(c1)C(=O)Nc1nc(c(CCN2CCCCC2)s1)-c1ccccc1

COc1cc(OC)cc(c1)C(=O)Nc1nc(c(s1)C1CCN(C)CC1)-c1ccccc1

CN1CCN(CC1)c1sc(NC(=O)c2cnn(C3CCOCC3)c2C)nc1C1CCC1

CN1CCN(CC1)c1sc(NC(=O)c2ccc(o2)-c2ccccc2)nc1C1CCC1

COc1cc(OC)cc(c1)C(=O)Nc1nc(c(s1)N1CCN(C)CC1)-c1cccnc1

Cc1nn(cc1C(=O)Nc1nc(C2CCC2)c(CCN2CCCCC2)s1)-c1ccc(F)cn1

CN1CCN(CC1)c1nc2cc(F)ccc2c(=O)n1-c1ccc(OC(F)(F)F)cc1

COc1ccc(cc1)-n1c(nc2cc(F)ccc2c1=O)N1CCN(C)CC1

CC(C)C[C@H](NC(=O)c1cc2ccccc2s1)C(=O)NCCCN(C)S(=O)(=O)c1ccc(Cl)cc1Cl |r|

CN1CCN(CC1)c1nc2c(F)cccc2c(=O)n1-c1ccc(Oc2ccccc2)cc1

CN1CCN(CC1)c1nc2ccc(F)cc2c(=O)n1-c1ccc(OC(F)(F)F)cc1

CN1CCN(CC1)c1nc2c(F)cccc2c(=O)n1-c1ccc(OC(F)(F)F)cc1

CC(C)c1ccc(cc1)-n1c(nc2c(F)cccc2c1=O)N1CCN(C)CC1

C[C@@H]1CN(C)CCN1c1nc2cc(F)ccc2c(=O)n1-c1ccc(cc1)C(F)(F)F |r|

CN1CCN(CC1(C)C)c1nc2cc(F)ccc2c(=O)n1-c1ccc(cc1)C(F)(F)F

CC(C)[C@H]1CN(CCN1C)c1nc2cc(F)ccc2c(=O)n1-c1ccc(cc1)C(F)(F)F |r|

CN1CCN(CC1)c1nc2c(F)cccc2c(=O)n1-c1ccc(Cc2ccccc2)cc1

CN1CCN(CC1)C2=Nc3c(cccc3F)C(=O)N2c4ccc(cc4)Oc5ccc(cc5)F

CN1CCN(CC1)c1nc2c(F)cccc2c(=O)n1-c1ccc(SC(F)(F)F)cc1

CN1CCN(CC1)c1nc2c(F)cccc2c(=O)n1-c1ccc(OC2CCOCC2)cc1

CCN1CCN(CC1)c1nc2cc(F)ccc2c(=O)n1-c1ccc(OC)cc1

CC(C)C[C@@H](C(=O)N1CCN(CC1)C(=O)[C@H](CO)NS(=O)(=O)c2ccc(cc2Cl)Cl)NC(=O)c3cc4ccccc4s3

CN1CCN(CC1)c1nc2cccc(F)c2c(=O)n1-c1ccc(OC(F)(F)F)cc1

CN1CCN(CC1)c1nc2c(F)cccc2c(=O)n1-c1ccc(cc1)C(F)(F)F

CCOC(=O)c1ccc(cc1)-n1c(nc2c(F)cccc2c1=O)N1CCN(C)CC1

COc1cc2CCN([C@@H](c3ccccc3)c2cc1OC)C(=O)N1CCc2cc(OC)c(OC)cc2[C@@H]1c1ccccc1 |r|

COc1cc2CCN([C@@H](c3ccc(F)cc3)c2cc1OC)C(=O)N1CCc2cc(OC)c(OC)cc2[C@@H]1c1ccc(F)cc1 |r|

[H][C@@]12Cc3c(OC)c(C)c(OC)c(OC)c3[C@H](N1C(=O)\C(NC2=O)=C\c1cc(OC)c(OC)c(C)c1OC)c1ccccc1 |r|

COc1cc2CCN([C@@H](c3ccc(Cl)cc3)c2cc1OC)C(=O)N1CCc2cc(OC)c(OC)cc2[C@@H]1c1ccc(Cl)cc1 |r|

CCCCC\C=C/C\C=C/C\C=C/CC1OC1CCCC(O)=O

[O-][N+](=O)c1cc(Cl)ccc1S(=O)(=O)N1CCN(Cc2ccccc2)CC1

CC(C)C[C@H](NC(=O)c1cc2ccccc2s1)C(=O)N1CCN(CC1)C(=O)[C@H](CO)NS(=O)(=O)c1ccccc1 |r|

[H][C@@]12[#8]-[#6](=O)-c3ccccc3-[#7]1-[#6@@H](\[#6]=[#6]\[#6])[C@@]([H])([#6@@H](-[#7]-c1ccccc1-[#6](-[#8])=O)-c1c3-[#8]C([#6])([#6])[#6@@H](-[#8])-[#6](=O)-c3cc(-[#6]\[#6]=[#6](\[#6])-[#6])c1\[#6]=[#6]\[#6]=[#6]\[#6])c1c(-[#6]\[#6]=[#6](\[#6])-[#6])cc3-[#6](=O)-[#6@@H](-[#8])C([#6])([#6])[#8]-c3c21 |r|

[#6]\[#6]=[#6]\[#6]=[#6]\c1c(-[#6]\[#6]=[#6](\[#6])-[#6])cc(-[#6]\[#6]=[#6](\[#6])-[#6])c(-[#8])c1-[#6]-[#8]

CCCCCc1cc(c(c(c1)O)[C@@H]2C=C(CC[C@H]2C(=C)C)C)O

CCCCCc1cc(O)c([C@@H]2C=C(C)CC[C@H]2C(C)=C)c(O)c1Cc1c(CCCCC)cc(O)c([C@@H]2C=C(C)CC[C@H]2C(C)=C)c1O |r,t:11,38|

Cc1ncccc1C(=O)N([C@@H](C(N)=O)c1ccccc1)[C@@H]1CCc2c1cc(Cl)cc2F |r|

OC(CCNS(=O)(=O)c1ccc(Cl)cc1Cl)COc1ccc(C#N)c(F)c1

NC(CCNS(=O)(=O)c1ccc(Cl)cc1Cl)COc1ccc(C#N)c(F)c1

CN(CCC(O)COc1ccc(C#N)c(F)c1)S(=O)(=O)c1ccc(Cl)cc1Cl

CN(CCC(N)COc1ccc(C#N)c(F)c1)S(=O)(=O)c1ccc(Cl)cc1Cl

N[C@@H](CCNS(=O)(=O)c1ccc(Cl)cc1Cl)COc1ccc(C#N)c(F)c1 |r|

N[C@H](CCNS(=O)(=O)c1ccc(Cl)cc1Cl)COc1ccc(C#N)c(F)c1 |r|

NC(CCNS(=O)(=O)c1ccccc1)COc1ccc(C#N)c(F)c1

NC(CCNS(=O)(=O)c1ccccc1Cl)COc1ccc(C#N)c(F)c1

NC(CCNS(=O)(=O)c1cccc(Cl)c1)COc1ccc(C#N)c(F)c1

NC(CCNS(=O)(=O)c1ccc(Cl)cc1)COc1ccc(C#N)c(F)c1

N[C@@H](CCNS(=O)(=O)c1ccc(cc1)C(F)(F)F)COc1ccc(C#N)c(F)c1 |r|

N[C@@H](CCNS(=O)(=O)c1ccc(cc1)C#N)COc1ccc(C#N)c(F)c1 |r|

COc1ccccc1S(=O)(=O)NCC[C@H](N)COc1ccc(C#N)c(F)c1 |r|

Cc1ccccc1S(=O)(=O)NCC[C@H](N)COc1ccc(C#N)c(F)c1 |r|

N[C@@H](CCNS(=O)(=O)c1ccccc1-c1ccccc1)COc1ccc(C#N)c(F)c1 |r|

N[C@@H](CCNS(=O)(=O)c1ccccc1OC(F)(F)F)COc1ccc(C#N)c(F)c1 |r|

N[C@@H](CCNS(=O)(=O)c1ccccc1C(F)(F)F)COc1ccc(C#N)c(F)c1 |r|

N[C@@H](CCNS(=O)(=O)c1ccccc1[N+]([O-])=O)COc1ccc(C#N)c(F)c1 |r|

N[C@@H](CCNS(=O)(=O)c1ccc(Cl)cc1C(F)(F)F)COc1ccc(C#N)c(F)c1 |r|

N[C@@H](CCNS(=O)(=O)c1ccc(cc1C(F)(F)F)C#N)COc1ccc(C#N)c(F)c1 |r|

N[C@@H](CCNS(=O)(=O)c1ccc(cc1Cl)C(F)(F)F)COc1ccc(C#N)c(F)c1 |r|

NC(CCNS(=O)(=O)c1ccc(Cl)cc1Cl)COc1ccccc1

NC(CCNS(=O)(=O)c1ccc(Cl)cc1Cl)COc1ccc(cc1)C#N

NC(CCNS(=O)(=O)c1ccc(Cl)cc1Cl)COc1cccc(c1)C#N

NC(CCNS(=O)(=O)c1ccc(Cl)cc1Cl)COc1ccccc1C#N

NC(CCNS(=O)(=O)c1ccc(Cl)cc1Cl)COc1cccc(F)c1

NC(CCNS(=O)(=O)c1ccc(Cl)cc1Cl)COc1cccc(Cl)c1

Cc1cccc(OCC(N)CCNS(=O)(=O)c2ccc(Cl)cc2Cl)c1

COc1cccc(OCC(N)CCNS(=O)(=O)c2ccc(Cl)cc2Cl)c1

N[C@@H](CCNS(=O)(=O)c1ccc(Cl)cc1Cl)COc1cc(ccc1N)C#N |r|

COc1ccc(cc1OC[C@@H](N)CCNS(=O)(=O)c1ccc(Cl)cc1Cl)C#N |r|

Cc1ccc(cc1OC[C@@H](N)CCNS(=O)(=O)c1ccc(Cl)cc1Cl)C#N |r|

N[C@@H](CCNS(=O)(=O)c1ccc(Cl)cc1Cl)COc1cc(ccc1F)C#N |r|

N[C@@H](CCNS(=O)(=O)c1ccc(Cl)cc1Cl)COc1cc(ccc1Cl)C#N |r|

Cn1c(Cl)cnc1CNc1ccc2sncc2c1

Clc1cnc(CNc2ccc3sncc3c2)s1

Clc1cnc(CNc2ccc3cnsc3c2)s1

c1c2cnsc2cc(c1Cl)NCc3ncc(s3)Cl

CC(C)(O)c1cnc(cn1)N1C[C@@]2(CC[C@@H](O)[C@](C)(Cn3cnc4ccc(cc34)C#N)C2)OC1=O |r|

CCCc1cc(c2c(c1)OC([C@H]3[C@H]2C=C(CC3)C)(C)C)O

[H][C@]1(CCC(C)=C[C@H]1c1c(O)cc(CCC)cc1O)C(C)=C |r,c:5|

[#6]-[#6]-[#6]-[#6]-[#6]-c1cc(-[#8])c(-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])c(-[#8])c1

[#6]-[#6]-[#6]-[#6]-[#6]-c1cc(-[#8])c2-[#6]=[#6]C([#6])([#6]-[#6]\[#6]=[#6](\[#6])-[#6])[#8]-c2c1 |c:10|

OC[C@H]1Cc2cc(ccc2[C@H](N1)c1cc(F)cc(Cl)c1)C#N |r|

COc1cc(CNC(=O)CCCc2ccc(I)s2)ccc1O

COc1cc(CNC(=O)CCCc2ccc(s2)-c2cccnc2)ccc1O

COc1cc(CNC(=O)CCCc2ccc(s2)-c2ccccc2)ccc1O

CC(C)Nc1nc2c(ncnc2n1C1CCN(CC1)c1ccc(cc1)N1c2ccccc2C(C)(C)c2ccccc12)C(=O)N(C)C

CC(C)Nc1nc2c(NC(C)=O)c(Cl)c(Cl)cc2n1C1CCN(CC1)c1ccc(cc1)C(C)(C)C#N

CC(C)Nc1nc2cc(ccc2n1C1CCN(CC1)c1ccc(cc1)C(C)(C)C#N)S(C)(=O)=O

CC(C)Nc1nc2ccc(cc2n1C1CCN(CC1)c1ccc(cc1)C(C)(C)C#N)C#N

CC(C)Nc1nc2c(NC(C)=O)c(Cl)c(Cl)cc2n1C1CCN(CC1)c1ccc(cc1)C1(CCC1)C#N

CC(C)Nc1nc2c(NC(C)=O)c(Cl)c(Cl)cc2n1C1CCN(CC1)c1ccc(cc1)C1(CCCC1)C#N

CC(C)Nc1nc2c(NC(C)=O)c(Cl)c(Cl)cc2n1C1CCN(CC1)c1ccc(cc1)C1(CCOCC1)C#N

CC(C)Nc1nc2c(NC(C)=O)c(Cl)c(Cl)cc2n1C1CCN(CC1)c1ccc(cc1)C(F)(F)F

CC(C)Nc1nc2c(NC(C)=O)c(Cl)c(Cl)cc2n1C1CCN(CC1)c1ccc(cc1)[N+]([O-])=O

CC(C)Nc1nc2cc(ccc2n1C1CCN(CC1)c1ccc(cc1)-n1c2ccccc2c2ccccc12)S(C)(=O)=O

CC(C)(C)c1ccc2[C@@H](CCc2c1)NC(=O)Nc1cccc2[nH]ncc12

COc1ccc(C2COc3cc(OCc4c(C)cc(C)cc4C)ccc3C2=O)cc1